Study the Effect of Ultrasonic Irradiation and Surfactant/Fe ions Weight Ratio on Morphology and Particle Size of Magnetite Nanoparticles Synthesised by co-precipitation for Medical Application

A biocompatible ferrofluid have been prepared by coprecipitation of FeCl2.4H2O and FeCl3.6H2O under ultrasonic irradiation and with NaOH as alkaline agent. Cystein was also used as capping agent in the solution. Magnetic properties of the produced ferrofluid were then determined by VSM test and magnetite nanoparticles were characterized by XRD and TEM techniques. The effect of surfactant to Fe ion weight ratio was also studied during this project by using two different amount of Dextran. Results showed the presence of a biocompatible superparamagnetic ferrofluid including magnetite nanoparticles with particle size ranging under 20 nm. The increase in the surfactant content results in the narrowing of the size distribution and reduction of the particle size and more solution stability.

A Study of Dose Distribution and Image Quality under an Automatic Tube Current Modulation (ATCM) System for a Toshiba Aquilion 64 CT Scanner Using a New Design of Phantom

Automatic tube current modulation (ATCM) systems are available for all CT manufacturers and are used for the majority of patients. Understanding how the systems work and their influence on patient dose and image quality is important for CT users, in order to gain the most effective use of the systems. In the present study, a new phantom was used for evaluating dose distribution and image quality under the ATCM operation for the Toshiba Aquilion 64 CT scanner using different ATCM options and a fixed mAs technique. A routine chest, abdomen and pelvis (CAP) protocol was selected for study and Gafchromic film was used to measure entrance surface dose (ESD), peripheral dose and central axis dose in the phantom. The results show the dose reductions achievable with various ATCM options, in relation with the target noise. The doses and image noise distribution were more uniform when the ATCM system was implemented compared with the fixed mAs technique. The lower limit set for the tube current will affect the modulations especially for the lower dose option. This limit prevented the tube current being reduced further and therefore the lower dose ATCM setting resembled a fixed mAs technique. Selection of a lower tube current limit is likely to reduce doses for smaller patients in scans of chest and neck regions.

Average Switching Thresholds and Average Throughput for Adaptive Modulation using Markov Model

The motivation for adaptive modulation and coding is to adjust the method of transmission to ensure that the maximum efficiency is achieved over the link at all times. The receiver estimates the channel quality and reports it back to the transmitter. The transmitter then maps the reported quality into a link mode. This mapping however, is not a one-to-one mapping. In this paper we investigate a method for selecting the proper modulation scheme. This method can dynamically adapt the mapping of the Signal-to- Noise Ratio (SNR) into a link mode. It enables the use of the right modulation scheme irrespective of changes in the channel conditions by incorporating errors in the received data. We propose a Markov model for this method, and use it to derive the average switching thresholds and the average throughput. We show that the average throughput of this method outperforms the conventional threshold method.

Predicting DHF Incidence in Northern Thailand using Time Series Analysis Technique

This study aimed at developing a forecasting model on the number of Dengue Haemorrhagic Fever (DHF) incidence in Northern Thailand using time series analysis. We developed Seasonal Autoregressive Integrated Moving Average (SARIMA) models on the data collected between 2003-2006 and then validated the models using the data collected between January-September 2007. The results showed that the regressive forecast curves were consistent with the pattern of actual values. The most suitable model was the SARIMA(2,0,1)(0,2,0)12 model with a Akaike Information Criterion (AIC) of 12.2931 and a Mean Absolute Percent Error (MAPE) of 8.91713. The SARIMA(2,0,1)(0,2,0)12 model fitting was adequate for the data with the Portmanteau statistic Q20 = 8.98644 ( x20,95= 27.5871, P>0.05). This indicated that there was no significant autocorrelation between residuals at different lag times in the SARIMA(2,0,1)(0,2,0)12 model.

A Comparative Analysis of Modulation Control Strategies for Cascade H-Bridge 11-Level Inverter

The range of the output power is a very important and evident limitation of two-level inverters. In order to overcome this disadvantage, multilevel inverters are introduced. Recently, Cascade H-Bridge inverters have emerged as one of the popular converter topologies used in numerous industrial applications. The modulation switching strategies such as phase shifted carrier based Pulse Width Modulation (PWM) technique and Stair case modulation with Selective Harmonic Elimination (SHE) PWM technique are generally used. NR method is used to solve highly non linear transcendental equations which are formed by SHEPWM method. Generally NR method has a drawback of requiring good initial guess but in this paper a new approach is implemented for NR method with any random initial guess. A three phase CHB 11-level inverter is chosen for analysis. MATLAB/SIMULINK programming environment and harmonic profiles are compared. Finally this paper presents a method at fundamental switching frequency with least % THDV.

New EEM/BEM Hybrid Method for Electric Field Calculation in Cable Joints

A power cable is widely used for power supply in power distributing networks and power transmission lines. Due to limitations in the production, delivery and setting up power cables, they are produced and delivered in several separate lengths. Cable itself, consists of two cable terminations and arbitrary number of cable joints, depending on the cable route length. Electrical stress control is needed to prevent a dielectric breakdown at the end of the insulation shield in both the air and cable insulation. Reliability of cable joint depends on its materials, design, installation and operating environment. The paper describes design and performance results for new modeled cable joints. Design concepts, based on numerical calculations, must be correct. An Equivalent Electrodes Method/Boundary Elements Method-hybrid approach that allows electromagnetic field calculations in multilayer dielectric media, including inhomogeneous regions, is presented.

Utilization of Glycerol Derived from Jatropha-s Biodiesel Production as a Cement Grinding Aid

Biodiesel production results in glycerol production as the main by-product in biodiesel industry.One of the utilizations of glycerol obtained from biodiesel production is as a cement grinding aid (CGA). Results showed that crude glycerol content was 40.19% whereas pure glycerol content was 82.15%. BSS value of the cement with CGA supplementation was higher than that of nonsupplemented cement (blank) indicating that CGA-supplemented cement had higher fineness than the non-supplemented one. It was also found that pure glycerol 95% and TEA 5% at 80ºC was the optimum CGA used to result in finest cement with BSS value of 4.836 cm2/g. Residue test showed that the smallest percent residue value (0.11%) was obtained in cement with supplementation of pure glycerol 95% and TEA 5%. Results of residue test confirmed those of BSS test showing that cement with supplementation of pure glycerol 95% and TEA 5% had the finest particle size.

A Review of Survey Methodology Employedin IT Outsourcing

The purpose of this paper is to provide an overview on methodological aspects of the information technology outsourcing (ITO) surveys, in an attempt to improve the data quality and reporting in survey research. It is based on a review of thirty articles on ITO surveys and focuses on two commonly explored dimensions of ITO, namely what are outsourced and why should there be ITO. This study highlights weaknesses in ITO surveys including lack of a clear definition of population, lack of information regarding the sampling method used, not citing the response rate, no information pertaining to pilot testing of survey instrument and absence of information on internal validity in the use or reporting of surveys. This study represents an attempt with a limited scope to point to shortfalls in the use survey methodology in ITO, and thus raise awareness among researchers in enhancing the reliability of survey findings.

Experimental Investigation of Phase Distributions of Two-phase Air-silicone Oil Flow in a Vertical Pipe

This paper reports the results of an experimental study conducted to characterise the gas-liquid multiphase flows experienced within a vertical riser transporting a range of gas-liquid flow rates. The scale experiments were performed using an air/silicone oil mixture within a 6 m long riser. The superficial air velocities studied ranged from 0.047 to 2.836 m/ s, whilst maintaining a liquid superficial velocity at 0.047 m/ s. Measurements of the mean cross-sectional and time average radial void fraction were obtained using a wire mesh sensor (WMS). The data were recorded at an acquisition frequency of 1000 Hz over an interval of 60 seconds. For the range of flow conditions studied, the average void fraction was observed to vary between 0.1 and 0.9. An analysis of the data collected concluded that the observed void fraction was strongly affected by the superficial gas velocity, whereby the higher the superficial gas velocity, the higher was the observed average void fraction. The average void fraction distributions observed were in good agreement with the results obtained by other researchers. When the air-silicone oil flows were fully developed reasonably symmetric profiles were observed, with the shape of the symmetry profile being strongly dependent on the superficial gas velocity.

Artificial Neural Network Model for a Low Cost Failure Sensor: Performance Assessment in Pipeline Distribution

This paper describes an automated event detection and location system for water distribution pipelines which is based upon low-cost sensor technology and signature analysis by an Artificial Neural Network (ANN). The development of a low cost failure sensor which measures the opacity or cloudiness of the local water flow has been designed, developed and validated, and an ANN based system is then described which uses time series data produced by sensors to construct an empirical model for time series prediction and classification of events. These two components have been installed, tested and verified in an experimental site in a UK water distribution system. Verification of the system has been achieved from a series of simulated burst trials which have provided real data sets. It is concluded that the system has potential in water distribution network management.

Migration from Commercial to in-House Developed Learning Management Systems

The Learning Management Systems present learning environment which offers a collection of e-learning tools in a package that allows a common interface and information sharing among the tools. South East European University initial experience in LMS was with the usage of the commercial LMS-ANGEL. After a three year experience on ANGEL usage because of expenses that were very high it was decided to develop our own software. As part of the research project team for the in-house design and development of the new LMS, we primarily had to select the features that would cover our needs and also comply with the actual trends in the area of software development, and then design and develop the system. In this paper we present the process of LMS in-house development for South East European University, its architecture, conception and strengths with a special accent on the process of migration and integration with other enterprise applications.

Design of QFT-Based Self-Tuning Deadbeat Controller

This paper presents a design method of self-tuning Quantitative Feedback Theory (QFT) by using improved deadbeat control algorithm. QFT is a technique to achieve robust control with pre-defined specifications whereas deadbeat is an algorithm that could bring the output to steady state with minimum step size. Nevertheless, usually there are large peaks in the deadbeat response. By integrating QFT specifications into deadbeat algorithm, the large peaks could be tolerated. On the other hand, emerging QFT with adaptive element will produce a robust controller with wider coverage of uncertainty. By combining QFT-based deadbeat algorithm and adaptive element, superior controller that is called selftuning QFT-based deadbeat controller could be achieved. The output response that is fast, robust and adaptive is expected. Using a grain dryer plant model as a pilot case-study, the performance of the proposed method has been evaluated and analyzed. Grain drying process is very complex with highly nonlinear behaviour, long delay, affected by environmental changes and affected by disturbances. Performance comparisons have been performed between the proposed self-tuning QFT-based deadbeat, standard QFT and standard dead-beat controllers. The efficiency of the self-tuning QFTbased dead-beat controller has been proven from the tests results in terms of controller’s parameters are updated online, less percentage of overshoot and settling time especially when there are variations in the plant.

In Vitro Antibacterial and Antifungal Effects of a 30 kDa D-Galactoside-Specific Lectin from the Demosponge, Halichondria okadai

The present study has been taken to explore the screening of in vitro antimicrobial activities of D-galactose-binding sponge lectin (HOL-30). HOL-30 was purified from the marine demosponge Halichondria okadai by affinity chromatography. The molecular mass of the lectin was determined to be 30 kDa with a single polypeptide by SDS-PAGE under non-reducing and reducing conditions. HOL-30 agglutinated trypsinized and glutaraldehydefixed rabbit and human erythrocytes with preference for type O erythrocytes. The lectin was subjected to evaluation for inhibition of microbial growth by the disc diffusion method against eleven human pathogenic gram-positive and gram-negative bacteria. The lectin exhibited strong antibacterial activity against gram-positive bacteria, such as Bacillus megaterium and Bacillus subtilis. However, it did not affect against gram-negative bacteria such as Salmonella typhi and Escherichia coli. The largest zone of inhibition was recorded of Bacillus megaterium (12 in diameter) and Bacillus subtilis (10 mm in diameter) at a concentration of the lectin (250 μg/disc). On the other hand, the antifungal activity of the lectin was investigated against six phytopathogenic fungi based on food poisoning technique. The lectin has shown maximum inhibition (22.83%) of mycelial growth of Botrydiplodia theobromae at a concentration of 100 μg/mL media. These findings indicate that the lectin may be of importance to clinical microbiology and have therapeutic applications.

Radiation Dose Distribution for Workers in South Korean Nuclear Power Plants

A total of 33,680 nuclear power plants (NPPs) workers were monitored and recorded from 1990 to 2007. According to the record, the average individual radiation dose has been decreasing continually from it 3.20 mSv/man in 1990 to 1.12 mSv/man at the end of 2007. After the International Commission on Radiological Protection (ICRP) 60 recommendation was generalized in South Korea, no nuclear power plant workers received above 20 mSv radiation, and the numbers of relatively highly exposed workers have been decreasing continuously. The age distribution of radiation workers in nuclear power plants was composed of mainly 20-30- year-olds (83%) for 1990 ~ 1994 and 30-40-year-olds (75%) for 2003 ~ 2007. The difference in individual average dose by age was not significant. Most (77%) of NPP radiation exposures from 1990 to 2007 occurred mostly during the refueling period. With regard to exposure type, the majority of exposures were external exposures, representing 95% of the total exposures, while internal exposures represented only 5%. External effective dose was affected mainly by gamma radiation exposure, with an insignificant amount of neutron exposure. As for internal effective dose, tritium (3H) in the pressurized heavy water reactor (PHWR) was the biggest cause of exposure.

FEA- Aided Design, Optimization and Development of an Axial Flux Motor for Implantable Ventricular Assist Device

This paper presents the optimal design and development of an axial flux motor for blood pump application. With the design objective of maximizing the motor efficiency and torque, different topologies of AFPM machine has been examined. Selection of optimal magnet fraction, Halbach arrangement of rotor magnets and the use of Soft Magnetic Composite (SMC) material for the stator core results in a novel motor with improved efficiency and torque profile. The results of the 3D Finite element analysis for the novel motor have been shown.

Gene Expressions Associated with Ultrastructural Changes in Vascular Endothelium of Atherosclerotic Lesion

Attachment of the circulating monocytes to the endothelium is the earliest detectable events during formation of atherosclerosis. The adhesion molecules, chemokines and matrix proteases genes were identified to be expressed in atherogenesis. Expressions of these genes may influence structural integrity of the luminal endothelium. The aim of this study is to relate changes in the ultrastructural morphology of the aortic luminal surface and gene expressions of the endothelial surface, chemokine and MMP-12 in normal and hypercholesterolemic rabbits. Luminal endothelial surface from rabbit aortic tissue was examined by scanning electron microscopy (SEM) using low vacuum mode to ascertain ultrastructural changes in development of atherosclerotic lesion. Gene expression of adhesion molecules, MCP-1 and MMP-12 were studied by Real-time PCR. Ultrastructural observations of the aortic luminal surface exhibited changes from normal regular smooth intact endothelium to irregular luminal surface including marked globular appearance and ruptures of the membrane layer. Real-time PCR demonstrated differentially expressed of studied genes in atherosclerotic tissues. The appearance of ultrastructural changes in aortic tissue of hypercholesterolemic rabbits is suggested to have relation with underlying changes of endothelial surface molecules, chemokine and MMP-12 gene expressions.

Enhanced Differentiation of Stromal Cells and Embryonic Stem Cells with Vitamin D3

In-vitro mouse co-culture of E14 embryonic stem cells (ESCs) and OP9 stromal cells can recapitulate the earliest stages of haematopoietic development, not accessible in human embryos, supporting both haemogenic precursors and their primitive haematopoietic progeny. 1α, 25-Dihydroxy-vitamin D3 (VD3) has been demonstrated to be a powerful differentiation inducer for a wide variety of neoplastic cells, and could enhance early differentiation of ESCs into blood cells in E14/OP9 co-culture. This study aims to ascertain whether VD3 is key in promoting differentiation and suppressing proliferation, by separately investigating the effects of VD3 on the proliferation phase of the E14 cell line and on stromal OP9 cells.The results showed that VD3 inhibited the proliferation of the cells in a dose-dependent manner, quantitatively by decreased cell number, and qualitatively by alkaline-phosphatase staining that revealed significant differences between VD3-treated and untreated cells, characterised by decreased enzyme expression (colourless cells). Propidium-iodide cell-cycle analyses showed no significant percentage change in VD3-treated E14 and OP9 cells within their G and S-phases, compared to the untreated controls, despite the increased percentage of G-phase compared to the S-phase in a dosedependent manner. These results with E14 and OP9 cells indicate that adequate VD3 concentration enhances cellular differentiation and inhibits proliferation. The results also suggest that if E14 and OP9 cells were co-cultured andVD3-treated, there would be furtherenhanced differentiation of ESCs into blood cells.

Simulation Study of DFIG Wind Turbine under Grid Fault

During recent years wind turbine technology has undergone rapid developments. Growth in size and the optimization of wind turbines has enabled wind energy to become increasingly competitive with conventional energy sources. As a result today-s wind turbines participate actively in the power production of several countries around the world. These developments raise a number of challenges to be dealt with now and in the future. The penetration of wind energy in the grid raises questions about the compatibility of the wind turbine power production with the grid. In particular, the contribution to grid stability, power quality and behavior during fault situations plays therefore as important a role as the reliability. In the present work, we addressed two fault situations that have shown their influence on the generator and the behavior of the wind over the defects which are briefly discussed based on simulation results.

Contact Problem for an Elastic Layered Composite Resting on Rigid Flat Supports

In this study, the contact problem of a layered composite which consists of two materials with different elastic constants and heights resting on two rigid flat supports with sharp edges is considered. The effect of gravity is neglected. While friction between the layers is taken into account, it is assumed that there is no friction between the supports and the layered composite so that only compressive tractions can be transmitted across the interface. The layered composite is subjected to a uniform clamping pressure over a finite portion of its top surface. The problem is reduced to a singular integral equation in which the contact pressure is the unknown function. The singular integral equation is evaluated numerically and the results for various dimensionless quantities are presented in graphical forms.

Numerical Analysis of All-Optical Microwave Mixing and Bandpass Filtering in an RoF Link

In this paper, all-optical signal processors that perform both microwave mixing and bandpass filtering in a radio-over-fiber (RoF) link are presented. The key device is a Mach-Zehnder modulator (MZM) which performs all-optical microwave mixing. An up-converted microwave signal is obtained and other unwanted frequency components are suppressed at the end of the fiber span.