L. - Journal Author

A Nanosensor System Based On Disuccinimydyl–CYP2E1 for Amperometric Detection of the Anti-Tuberculosis Drug, Pyrazinamide

Year: 2014 Volume: 8 Issue: 2 67 - 71 Pages

Abstract: Pyrazinamide (PZA) is among the first-line pro-drugs in the tuberculosis (TB) combination chemotherapy used to treat Mycobacterium tuberculosis. Numerous reports have suggested that hepatotoxicity due to pyrazinamide in patients is due to inappropriate dosing. It is, therefore necessary to develop sensitive and reliable techniques for determining the PZA metabolic profile of diagnosed patients promptly and at point-of-care. This study reports the determination of PZA based on nanobiosensor systems developed from disuccinimidyl octanedioate modified Cytochrome P450-2E1 (CYP2E1) electrodeposited on gold substrates derivatised with (poly(8-anilino-1-napthalene sulphonic acid) PANSA/PVP-AgNPs nanocomposites. The rapid and sensitive amperometric PZA detection gave a dynamic linear range of 2µM to 16µM revealing a limit of detection of 0.044µM and a sensitivity of 1.38µA/µM. The Michaelis-Menten parameters; KM, KM app and IMAX were calculated to be 6.0µM, 1.41µM and 1.51x10-6 A, respectively, indicating a nanobiosensor suitable for use in serum.

The Estimation of Human Vital Signs Complexity

Year: 2014 Volume: 8 Issue: 1 39 - 44 Pages

Abstract: Nonstationary and nonlinear signals generated by living complex systems defy traditional mechanistic approaches, which are based on homeostasis. Previous our studies have shown that the evaluation of the interactions of physiological signals by using special analysis methods is suitable for observation of physiological processes. It is demonstrated the possibility of using deep physiological model, based on the interpretation of the changes of the human body’s functional states combined with an application of the analytical method based on matrix theory for the physiological signals analysis, which was applied on high risk cardiac patients. It is shown that evaluation of cardiac signals interactions show peculiar for each individual functional changes at the onset of hemodynamic restoration procedure. Therefore, we suggest that the alterations of functional state of the body, after patients overcome surgery can be complemented by the data received from the suggested approach of the evaluation of functional variables’ interactions.

Incidence of Gastrointestinal Parasites among Workers in Major Abattoirs in Port Harcourt, Rivers State, Nigeria

Year: 2013 Volume: 7 Issue: 11 750 - 752 Pages

Abstract: Gastrointestinal parasitic infections are common health problems in sub-Saharan Africa. A cross- sectional study was carried out to determine the prevalence of gastrointestinal parasites among workers in major abattoirs in Port Harcourt, Nigeria. These abattoirs are located in Trans-Amadi, Rumuodumaya, Mile III and Easter-by-Pass. Formol-ether concentration technique was used to isolate the ova and cysts from faecal samples. Out of 201 workers (herdsmen, butchers, and cleaners) investigated for the presence of these parasites, 89 (44.2%) were infected with one or more parasites. The prevalence of the parasites among herdsmen and cleaners was significantly (P0.05) difference in the prevalence of gastrointestinal parasites in relation to age. Parasites identified included Ascaris lumbricoide (33.3%), tapeworm (4.97%), Entamoeba histolytica (5.47%), hookworms (13.9%), Trichuris trichiura (9.95%), Gardia lamblia (3.48%), and Schistosoma mansoni (1.9%). The frequency of A. lumbricoide was significantly (P

Effect of Partial Rootzone Drying on Growth, Yield and Biomass Partitioning of a Soilless Tomato Crop

Year: 2013 Volume: 7 Issue: 11 1082 - 1085 Pages

Abstract: The object of the present research was to assess the effects of partial rootzone drying (PRD) on tomato growth, productivity, biomass allocation and water use efficiency (WUE). Plants were grown under greenhouse, on a sand substrate. Three treatments were applied: a control that was fully and conventionally irrigated, PRD-70 and PRD-50 in which, respectively, 70% and 50% of water requirements were supplied using PRD. Alternation of irrigation between the two root halves took place each three days. The Control produces the highest total yield (252tons/ha). In terms of fruit number, PRD-50 showed 23% and 16% less fruits than PRD-70 and control, respectively. Fruit size was affected by treatment with PRD-50 treatment producing 66% and 53% more class 3 fruits than, control and PRD-70, respectively. For plant growth, the difference was not significant when comparing control to PRD-70 but was significant when comparing PRD-70 and control to PRD-50. No effect was on total biomass but root biomass was higher for stressed plants compared to control. WUE was 66% and 27% higher for PRD-50 and PRD-70 respectively compared to control.

Antimicrobial Effect of Essential Oil of Plant Schinus molle on Some Bacteria Pathogens

Year: 2013 Volume: 7 Issue: 12 1041 - 1043 Pages

Authors:
Mehani M.
Segni L.

Abstract: Humans use plants for thousands of years to treat various ailments, in many developing countries; much of the population relies on traditional doctors and their collections of medicinal plants to cure them. Essential oils have many therapeutic properties. In herbal medicine, they are used for their antiseptic properties against infectious diseases of fungal origin, against dermatophytes, those of bacterial origin. The aim of our study is to determine the antimicrobial effect of essential oils of the plant Schinus molle on some pathogenic bacteria. It is a medicinal plant used in traditional therapy. Essential oils have many therapeutic properties. In herbal medicine, they are used for their antiseptic properties against infectious diseases of fungal origin, against dermatophytes, those of bacterial origin. The test adopted, is based on the diffusion method on solid medium (Antibiogram), this method allows to determine the susceptibility or resistance of an organism according to the sample studied. Our study reveals that the essential oil of the plant Schinus molle has a different effect on the resistance of germs: for Pseudomonas aeruginosa strain is a moderately sensitive with an inhibition zone of 10mm, further Enterobacter, Escherichia coli and Proteus are strains that represent a high sensitivity, a zone of inhibition equal to 14.66 mm.

Phase-Averaged Analysis of Three-Dimensional Vorticity in the Wake of Two Yawed Side-By-Side Circular Cylinders

Year: 2014 Volume: 8 Issue: 1 27 - 36 Pages

Abstract: Thewake flow behind two yawed side-by-sidecircular cylinders is investigated using athree-dimensional vorticity probe. Four yaw angles (α), namely, 0°, 15°, 30° and 45° and twocylinder spacing ratios T* of 1.7 and 3.0 were tested. For T* = 3.0, there exist two vortex streets and the cylinders behave as independent and isolated ones. The maximum contour value of the coherent streamwise vorticity ~* ωx is only about 10% of that of the spanwise vorticity ~* ωz . With the increase of α, ~* ωx increases whereas ~* ωz decreases. At α = 45°, ~* ωx is about 67% of ~* ωz .For T* = 1.7, only a single peak is detected in the energy spectrum. The spanwise vorticity contours have an organized pattern only at α = 0°. The maximum coherent vorticity contours of ~* ω x and ~* ωz for T* = 1.7 are about 30% and 7% of those for T* = 3.0.The independence principle (IP)in terms of Strouhal numbers is applicable in both wakes when α< 40°.

A Novel Application of Network Equivalencing Method in Time Domain to Precise Calculation of Dead Time in Power Transmission Title

Year: 2013 Volume: 7 Issue: 3 343 - 348 Pages

Abstract: Various studies have showed that about 90% of single line to ground faults occurred on High voltage transmission lines have transient nature. This type of faults is cleared by temporary outage (by the single phase auto-reclosure). The interval between opening and reclosing of the faulted phase circuit breakers is named “Dead Time” that is varying about several hundred milliseconds. For adjustment of traditional single phase auto-reclosures that usually are not intelligent, it is necessary to calculate the dead time in the off-line condition precisely. If the dead time used in adjustment of single phase auto-reclosure is less than the real dead time, the reclosing of circuit breakers threats the power systems seriously. So in this paper a novel approach for precise calculation of dead time in power transmission lines based on the network equivalencing in time domain is presented. This approach has extremely higher precision in comparison with the traditional method based on Thevenin equivalent circuit. For comparison between the proposed approach in this paper and the traditional method, a comprehensive simulation by EMTP-ATP is performed on an extensive power network.

Spark Breakdown Voltage and Surface Degradation of Multiwalled Carbon Nanotube Electrode Surfaces

Year: 2013 Volume: 7 Issue: 2 347 - 352 Pages

Abstract: Silicon substrates coated with multiwalled carbon nanotubes (MWCNTs) were experimentally investigated to determine spark breakdown voltages relative to uncoated surfaces, the degree of surface degradation associated with the spark discharge, and techniques to minimize the surface degradation. The results may be applicable to instruments or processes that use MWCNT as a means of increasing local electric field strength and where spark breakdown is a possibility that might affect the devices’ performance or longevity. MWCNTs were shown to reduce the breakdown voltage of a 1mm gap in air by 30-50%. The relative decrease in breakdown voltage was maintained over gap distances of 0.5 to 2mm and gauge pressures of 0 to 4 bar. Degradation of the MWCNT coated surfaces was observed. Several techniques to improve durability were investigated. These included: chromium and gold-palladium coatings, tube annealing, and embedding clusters of MWCNT in a ceramic matrix.

Isolation and Screening of Fungi for Aerobic Delignification and Reduction of AOX of Pulp and Paper Mill Effluent

Year: 2013 Volume: 7 Issue: 12 1167 - 1171 Pages

Abstract: Water pollution is a major concern for the pulp and paper industry due to the large quantities of effluents generated. Biodegradation of industrial Lignin and AOX by a fungal isolate identified as Aspergillus flavus, white rot fungi which was isolated from Pulp and Paper effluent was studied in batch flask system with industrial effluent and synthetic solution. The flasks were operated at temperature 32°C at 200rpm for eight days in continuous mode. The average overall pH, Temperature, DO, C.O.D, T.D.S, T.S.S, Lignin, AOX were up to 4.56, 32oC, 4.2mg/l, 104mg/l, 6000 mg/l, 4000mg/l, 575.5mg/l, 2195 mg/l respectively after treatment. The Aspergillus flavus sp was the most effective in the biodegradation of Lignin of pulp industry for 94% at 480nm, AOX for 62% at 510nm and of chemical oxygen demand levels for 45% after 8 days of incubation. The optimal conditions found were 4 pH and 32oC temperature for lignin and AOX degradation.

Conceptual Synthesis of Multi-Source Renewable Energy Based Microgrid

Year: 2013 Volume: 7 Issue: 12 1687 - 1692 Pages

Abstract: Microgrids are increasingly being considered to provide electricity for the expanding energy demand in the grid distribution network and grid isolated areas. However, the technical challenges associated with the operation and controls are immense. Management of dynamic power balances, power flow, and network voltage profiles imposes unique challenges in the context of microgrids. Stability of the microgrid during both grid-connected and islanded mode is considered as the major challenge during its operation. Traditional control methods have been employed are based on the assumption of linear loads. For instance the concept of PQ, voltage and frequency control through decoupled PQ are some of very useful when considering linear loads, but they fall short when considering nonlinear loads. The deficiency of traditional control methods of microgrid suggests that more research in the control of microgrids should be done. This research aims at introducing the dq technique concept into decoupled PQ for dynamic load demand control in inverter interfaced DG system operating as isolated LV microgrid. Decoupled PQ in exact mathematical formulation in dq frame is expected to accommodate all variations of the line parameters (resistance and inductance) and to relinquish forced relationship between the DG variables such as power, voltage and frequency in LV microgrids and allow for individual parameter control (frequency and line voltages). This concept is expected to address and achieve accurate control, improve microgrid stability and power quality at all load conditions.

Behaviours of Energy Spectrum at Low Reynolds Numbers in Grid Turbulence

Year: 2013 Volume: 7 Issue: 12 2446 - 2450 Pages

Abstract: This paper reports an experimental investigation of the energy spectrum of turbulent velocity fields at low Reynolds numbers in grid turbulence. Hot wire measurements are carried out in grid turbulence with subjected to a 1.36:1 contraction of the wind tunnel. Three different grids are used: (i) large square perforated grid (mesh size 43.75mm), (ii) small square perforated grid (mesh size 14. and (iii) woven mesh grid (mesh size 5mm). The results indicate that the energy spectrum at small Reynolds numbers does not follow Kolmogorov’s universal scaling. It is further found that the critical Reynolds number, below which the scaling breaks down, is around 25.

The Biomechanics of Cycling with a Transtibial Prosthesis: A Case Study of a Professional Cyclist

Year: 2013 Volume: 7 Issue: 12 816 - 821 Pages

Abstract: The article deals with biomechanics of cyclist with unilateral transtibial amputation. Transtibial amputation completely removes ankle and part of muscles of a lower leg which are responsible for production of force during pedaling and causes significant geometric and power asymmetry between the limbs during cycling movement. The primary goal of this work is to assess the effects of length adjustment of the crank on the kinematics and muscle activity of cyclist. The paper presents experimental work, which aims to find a suitable ratio of the length of kinematic components to improve overall athletic performance. The study presents the results of the kinematic analysis of the cycling movement with different crank length realized by tracking camera system together with the results of muscle activity measurements captured by electromyography and measurement of forces in the cranks by strain gauges.

A Comparison of Transdiagnostic Components in Generalized Anxiety Disorder, Unipolar Mood Disorder and Nonclinical Population

Year: 2013 Volume: 7 Issue: 12 807 - 815 Pages

Abstract: Background: Dimensional and transdiagnostic approaches as a result of high comorbidity among mental disorders have captured researchers and clinicians interests for exploring the latent factors to development and maintenance of some psychological disorders. The goal of present study is comparing some of these common factors between generalized anxiety disorder and unipolar mood disorder. Methods: 27 patients with generalized anxiety disorder, 29 patients with depression disorder were recruited by using SCID-I and 69 non-clinical populations were selected by using GHQ cut off point. MANCOVA was used for analyzing data. Results: The results show that worry, rumination, intolerance of uncertainty, maladaptive metacognitive beliefs, and experiential avoidance were all significantly different between GAD and unipolar mood disorder groups. However, there weren’t any significant differences in difficulties in emotion regulation and neuroticism between GAD and unipolar mood disorder groups. Discussion: Results indicate that although there are some transdiagnostic and common factors in GAD and unipolar mood disorder, there may be some specific vulnerability factors for each disorder. Further study is needed for answering these questions.

The Optimal Indirect Vector Controller Design via an Adaptive Tabu Search Algorithm

Year: 2013 Volume: 7 Issue: 11 1434 - 1439 Pages

Abstract: The paper presents how to design the indirect vector control of three-phase induction motor drive systems using the artificial intelligence technique called the adaptive tabu search. The results from the simulation and the experiment show that the drive system with the controller designed from the proposed method can provide the best output speed response compared with those of the conventional method. The controller design using the proposed technique can be used to create the software package for engineers to achieve the optimal controller design of the induction motor speed control based on the indirect vector concept.

Observation and Experience of Using Mechanically Activated Fly Ash in Concrete

Year: 2013 Volume: 7 Issue: 11 860 - 863 Pages

Abstract: Paper focuses on experimental testing of possibilities of mechanical activation of fly ash and observation of influence of specific surface and granulometry on final properties of fresh and hardened concrete. Mechanical grinding prepared various fineness of fly ash, which was classed by specific surface in accordance with Blain and their granulometry was determined by means of laser granulometer. Then, sets of testing specimens were made from mix designs of identical composition with 25% or Portland cement CEM I 42.5 R replaced with fly ash with various specific surface and granulometry. Mix design with only Portland cement was used as reference. Mix designs were tested on consistency of fresh concrete and compressive strength after 7, 28, 60 and 90 days.

Exercise and Cognitive Function: Time Course of the Effects

Year: 2013 Volume: 7 Issue: 11 2941 - 2946 Pages

Abstract: Previous research has indicated a variable effect of exercise on adolescents’ cognitive function. However, comparisons between studies are difficult to make due to differences in: the mode, intensity and duration of exercise employed; the components of cognitive function measured (and the tests used to assess them); and the timing of the cognitive function tests in relation to the exercise. Therefore, the aim of the present study was to assess the time course (10 and 60min post-exercise) of the effects of 15min intermittent exercise on cognitive function in adolescents. 45 adolescents were recruited to participate in the study and completed two main trials (exercise and resting) in a counterbalanced crossover design. Participants completed 15min of intermittent exercise (in cycles of 1 min exercise, 30s rest). A battery of computer based cognitive function tests (Stroop test, Sternberg paradigm and visual search test) were completed 30 min pre- and 10 and 60min post-exercise (to assess attention, working memory and perception respectively).The findings of the present study indicate that on the baseline level of the Stroop test, 10min following exercise response times were slower than at any other time point on either trial (trial by session time interaction, p = 0.0308). However, this slowing of responses also tended to produce enhanced accuracy 10min post-exercise on the baseline level of the Stroop test (trial by session time interaction, p = 0.0780). Similarly, on the complex level of the visual search test there was a slowing of response times 10 min post-exercise (trial by session time interaction, p = 0.0199). However, this was not coupled with an improvement in accuracy (trial by session time interaction, p = 0.2349). The mid-morning bout of exercise did not affect response times or accuracy across the morning on the Sternberg paradigm. In conclusion, the findings of the present study suggest an equivocal effect of exercise on adolescents' cognitive function. The mid-morning bout of exercise appears to cause a speed-accuracy trade off immediately following exercise on the Stroop test (participants become slower but more accurate), whilst slowing response times on the visual search test and having no effect on performance on the Sternberg paradigm. Furthermore, this work highlights the importance of the timing of the cognitive function tests relative to the exercise and the components of cognitive function examined in future studies.

Soil Compaction in Tropical Organic Farming Systems and Its Impact on Natural Soil-Borne Disease Suppression: Challenges for Management

Year: 2013 Volume: 7 Issue: 11 2938 - 2940 Pages

Authors:
Ishak
L.
McHenry
M. T.
Brown
P. H.

Abstract: Organic farming systems still depend on intensive, mechanical soil tillage. Frequent passes by machinery traffic cause substantial soil compaction that threatens soil health. Adopting practices as reduced tillage and organic matter retention on the soil surface are considered effective ways to control soil compaction. In tropical regions, however, the acceleration of soil organic matter decomposition and soil carbon turnover on the topsoil layer is influenced more rapidly by the oscillation process of drying and wetting. It is hypothesized therefore, that rapid reduction in soil organic matter hastens the potential for compaction to occur in organic farming systems. Compaction changes soil physical properties and as a consequence it has been implicated as a causal agent in the inhibition of natural disease suppression in soils. Here we describe relationships between soil management in organic vegetable systems, soil compaction, and declining soil capacity to suppress pathogenic microorganisms.

Q-Learning with Eligibility Traces to Solve Non-Convex Economic Dispatch Problems

Year: 2012 Volume: 6 Issue: 7 730 - 737 Pages

Abstract: Economic Dispatch is one of the most important power system management tools. It is used to allocate an amount of power generation to the generating units to meet the load demand. The Economic Dispatch problem is a large scale nonlinear constrained optimization problem. In general, heuristic optimization techniques are used to solve non-convex Economic Dispatch problem. In this paper, ideas from Reinforcement Learning are proposed to solve the non-convex Economic Dispatch problem. Q-Learning is a reinforcement learning techniques where each generating unit learn the optimal schedule of the generated power that minimizes the generation cost function. The eligibility traces are used to speed up the Q-Learning process. Q-Learning with eligibility traces is used to solve Economic Dispatch problems with valve point loading effect, multiple fuel options, and power transmission losses.

Creeping Insulation - Hong Kong Green Wall

Year: 2013 Volume: 7 Issue: 11 748 - 753 Pages

Abstract: Hong Kong is a densely populated city suffering badly from the urban heat island effect. Green wall offers a means of ameliorating the situation but there are doubts over its suitability in Hong Kong’s unique environment. In this paper, we look at the potential for green walls in Hong Kong first by summarizing some of the Chinese green walling systems and associated vegetation in use, then by an introduction to three existing green walls in Hong Kong, and finally through a small experiment aimed at identifying the likely main effects of green walled housing. The results indicate that green walling in Hong Kong is likely to provide enhanced internal house environment in terms of warm weather temperature reduction, stabilization and damping, with direct energy savings in air-conditioning and indirect district benefits of reduced heat island effect and carbon emissions. The green walling insulation properties also suggest the possibility of warmer homes in winter and/or energy savings in mechanical heating provision.

Effect of Nutrient Supply on Yield and Photosynthetic Parameters of Maize Hybrids

Year: 2013 Volume: 7 Issue: 11 1035 - 1038 Pages

Abstract: We examined the crop yield results of hybrids in 2012. We found out that in the control treatments the lowest yield was reached with the hybrid PR37M81: 10,012 kg ha-1. The highest yield was in case of hybrid P37N01: 11,581 kg ha-1. As we raised the nutrient doses the lowest yield of all examined nutrient levels was in case of hybrid PR37M81. We measured at N60+PK nutrient level 12,517 kg ha-1, at N120+PK nutrient level 12,760 kg ha-1, and at N150+PK nutrient level 12,535 kg ha-1 yield results. At N60+PK and N120+PK nutrient level the highest yield was reached with the hybrid P9494 (N60+PK: 13,970 kg ha-1, N120+PK: 13,871 kg ha-1). In case of the N150+PK fertilization treatment the hybrid P37N01 gave the highest yield results (13,962 kg ha-1).

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