Abstract: MiRNAs participate in gene regulation of translation.
Some studies have investigated the interactions between genes and
intragenic miRNAs. It is important to study the miRNA binding sites
of genes involved in carcinogenesis. RNAHybrid 2.1 and ERNAhybrid
programmes were used to compute the hybridization free
energy of miRNA binding sites. Of these 54 mRNAs, 22.6%, 37.7%,
and 39.7% of miRNA binding sites were present in the 5'UTRs,
CDSs, and 3'UTRs, respectively. The density of the binding sites for
miRNAs in the 5'UTR ranged from 1.6 to 43.2 times and from 1.8 to
8.0 times greater than in the CDS and 3'UTR, respectively. Three
types of miRNA interactions with mRNAs have been revealed: 5'-
dominant canonical, 3'-compensatory, and complementary binding
sites. MiRNAs regulate gene expression, and information on the
interactions between miRNAs and mRNAs could be useful in
molecular medicine. We recommend that newly described sites
undergo validation by experimental investigation.
Abstract: The study is based on the assumption that media products are appropriate subjects for the exploration of social and cultural identities as a keystone of value orientations of their authors, producers and target audiences. The research object of the study is the title page of the book cover of a professional publication that serves as a medium of marketing, scientific and intercultural communication, which is the result of semiotic and intercultural transfer. The study aims to answer the question whether the book cover is an expression of conceptualization and tool for social identity construction. It attempts to determine what value orientations and what concepts of social and cultural identities are hidden in the narrative structures of the book cover of the Czech translation of the book by G. Ritzer The McDonaldization of Society (1993), issued after the fall of the iron curtain in 1996 in the Czech Republic.
Abstract: Medical image registration is the key technology in image guided radiation therapy (IGRT) systems. On the basis of the previous work on our IGRT prototype with a biorthogonal x-ray imaging system, we described a method focused on the 2D/2D rigid-body registration using multiresolution pyramid based mutual information in this paper. Three key steps were involved in the method ： firstly, four 2D images were obtained including two x-ray projection images and two digital reconstructed radiographies（DRRs ） as the input for the registration ； Secondly, each pair of the corresponding x-ray image and DRR image were matched using multiresolution pyramid based mutual information under the ITK registration framework ； Thirdly, we got the final couch offset through a coordinate transformation by calculating the translations acquired from the two pairs of the images. A simulation example of a parotid gland tumor case and a clinical example of an anthropomorphic head phantom were employed in the verification tests. In addition, the influence of different CT slice thickness were tested. The simulation results showed that the positioning errors were 0.068±0.070, 0.072±0.098, 0.154±0.176mm along three axes which were lateral, longitudinal and vertical. The clinical test indicated that the positioning errors of the planned isocenter were 0.066, 0.07, 2.06mm on average with a CT slice thickness of 2.5mm. It can be concluded that our method with its verified accuracy and robustness can be effectively used in IGRT systems for patient setup.
Abstract: Developed tool is one of system tools for easier access to various scientific areas and real time interactive learning between
lecturer and for hearing impaired students. There is no demand for the lecturer to know Sign Language (SL). Instead, the new software
tools will perform the translation of the regular speech into SL, after
which it will be transferred to the student. On the other side, the
questions of the student (in SL) will be translated and transferred to
the lecturer in text or speech. One of those tools is presented tool. It-s
too for developing the correct Speech Visemes as a root of total communication method for hearing impared students.
Abstract: In this paper, the effects of the restoring force device on the response of a space frame structure resting on sliding type of bearing with a restoring force device is studied. The NS component of the El - Centro earthquake and harmonic ground acceleration is considered for earthquake excitation. The structure is modeled by considering six-degrees of freedom (three translations and three rotations) at each node. The sliding support is modeled as a fictitious spring with two horizontal degrees of freedom. The response quantities considered for the study are the top floor acceleration, base shear, bending moment and base displacement. It is concluded from the study that the displacement of the structure reduces by the use of the restoring force device. Also, the peak values of acceleration, bending moment and base shear also decreases. The simulation results show the effectiveness of the developed and proposed method.
Abstract: One major difficulty that faces developers of
concurrent and distributed software is analysis for concurrency based
faults like deadlocks. Petri nets are used extensively in the
verification of correctness of concurrent programs. ECATNets [2] are
a category of algebraic Petri nets based on a sound combination of
algebraic abstract types and high-level Petri nets. ECATNets have
'sound' and 'complete' semantics because of their integration in
rewriting logic [12] and its programming language Maude [13].
Rewriting logic is considered as one of very powerful logics in terms
of description, verification and programming of concurrent systems.
We proposed in [4] a method for translating Ada-95 tasking
programs to ECATNets formalism (Ada-ECATNet). In this paper,
we show that ECATNets formalism provides a more compact
translation for Ada programs compared to the other approaches based
on simple Petri nets or Colored Petri nets (CPNs). Such translation
doesn-t reduce only the size of program, but reduces also the number
of program states. We show also, how this compact Ada-ECATNet
may be reduced again by applying reduction rules on it. This double
reduction of Ada-ECATNet permits a considerable minimization of
the memory space and run time of corresponding Maude program.
Abstract: We study the dynamic response of a wind turbine
structure subjected to theoretical seismic motions, taking into account
the rotational component of ground shaking. Models are generated
for a shallow moderate crustal earthquake in the Madrid Region
(Spain). Synthetic translational and rotational time histories are
computed using the Discrete Wavenumber Method, assuming a point
source and a horizontal layered earth structure. These are used to
analyze the dynamic response of a wind turbine, represented by a
simple finite element model. Von Mises stress values at different
heights of the tower are used to study the dynamical structural
response to a set of synthetic ground motion time histories
Abstract: Internet Protocol version 4 (IPv4) address is decreasing and a rapid transition method to the next generation IP address (IPv6) should be established. This study aims to evaluate and select the best performance of the IPv6 address network transitionmechanisms, such as IPv4/IPv6 dual stack, transport Relay Translation (TRT) and Reverse Proxy with additional features. It is also aim to prove that faster access can be done while ensuring optimal usage of available resources used during the test and actual implementation. This study used two test methods such asInternet Control Message Protocol (ICMP)ping and ApacheBenchmark (AB) methodsto evaluate the performance.Performance metrics for this study include aspects ofaverageaccessin one second,time takenfor singleaccess,thedata transfer speed and the costof additional requirements.Reverse Proxy with Caching featureis the most efficientmechanism because of it simpler configurationandthe best performerfrom the test conducted.
Abstract: Feature-based registration is an effective technique for clinical use, because it can greatly reduce computational costs. However, this technique, which estimates the transformation by using feature points extracted from two images, may cause misalignments. To handle with this limitation, we propose to extract the salient edges and extracted control points (CP) of medical images by using efficiency of multiresolution representation of data nonsubsampled contourlet transform (NSCT) that finds the best feature points. The MR images were first decomposed using the NSCT, and then Edge and CP were extracted from bandpass directional subband of NSCT coefficients and some proposed rules. After edge and CP extraction, mutual information was adopted for the registration of feature points and translation parameters are calculated by using particle swarm optimization (PSO). The experimental results showed that the proposed method produces totally accurate performance for registration medical CT-MR images.
Abstract: This paper presents an online method that learns the
corresponding points of an object from un-annotated grayscale images
containing instances of the object. In the first image being
processed, an ensemble of node points is automatically selected
which is matched in the subsequent images. A Bayesian posterior
distribution for the locations of the nodes in the images is formed.
The likelihood is formed from Gabor responses and the prior assumes
the mean shape of the node ensemble to be similar in a translation
and scale free space. An association model is applied for separating
the object nodes and background nodes. The posterior distribution is
sampled with Sequential Monte Carlo method. The matched object
nodes are inferred to be the corresponding points of the object
instances. The results show that our system matches the object nodes
as accurately as other methods that train the model with annotated
training images.
Abstract: Word sense disambiguation is one of the most important open problems in natural language processing applications such as information retrieval and machine translation. Many approach strategies can be employed to resolve word ambiguity with a reasonable degree of accuracy. These strategies are: knowledgebased, corpus-based, and hybrid-based. This paper pays attention to the corpus-based strategy that employs an unsupervised learning method for disambiguation. We report our investigation of Latent Semantic Indexing (LSI), an information retrieval technique and unsupervised learning, to the task of Thai noun and verbal word sense disambiguation. The Latent Semantic Indexing has been shown to be efficient and effective for Information Retrieval. For the purposes of this research, we report experiments on two Thai polysemous words, namely /hua4/ and /kep1/ that are used as a representative of Thai nouns and verbs respectively. The results of these experiments demonstrate the effectiveness and indicate the potential of applying vector-based distributional information measures to semantic disambiguation.
Abstract: An effective visual error concealment method has been presented by employing a robust rotation, scale, and translation (RST) invariant partial patch matching model (RSTI-PPMM) and
exemplar-based inpainting. While the proposed robust and inherently
feature-enhanced texture synthesis approach ensures the generation
of excellent and perceptually plausible visual error concealment results, the outlier pruning property guarantees the significant quality improvements, both quantitatively and qualitatively. No intermediate
user-interaction is required for the pre-segmented media and the
presented method follows a bootstrapping approach for an automatic
visual loss recovery and the image and video error concealment.
Abstract: Representation and description of object shapes by the
slopes of their contours or borders are proposed. The idea is to capture
the essence of the features that make it easier for a shape to be
stored, transmitted, compared and recognized. These features must
be independent of translation, rotation and scaling of the shape. A
approach is proposed to obtain high performance, efficiency and to
merge the boundaries into sequence of straight line segments with
the fewest possible segments. Evaluation on the performance of the
proposed method is based on its comparison with established method
of object shape description.
Abstract: Mutations of the telomeric copy of the survival motor neuron 1 (SMN1) gene cause spinal muscular atrophy. A deletion of the Eef1a2 gene leads to lower motor neuron degeneration in wasted mice. Indirect evidences have been shown that the eEF1A protein family may interact with SMN, and our previous study showed that abnormalities of neuromuscular junctions in wasted mice were similar to those of Smn mutant mice. To determine potential colocalization between SMN and tissue-specific translation elongation factor 1A2 (eEF1A2), an immunochemical analysis of HeLa cells transfected with the plasmid pcDNA3.1(+)C-hEEF1A2- myc and a new quantitative test of colocalization by intensity correlation analysis (ICA) was used to explore the association of SMN and eEF1A2. Here the results showed that eEF1A2 redistributed from the cytoplasm to the nucleus in response to serum and epidermal growth factor. In the cytoplasm, compelling evidence showed that staining for myc-tagged eEF1A2 varied in synchrony with that for SMN, consistent with the formation of a SMN-eEF1A2 complex in the cytoplasm of HeLa cells. These findings suggest that eEF1A2 may colocalize with SMN in the cytoplasm and may be a component of the SMN complex. However, the limitation of the ICA method is an inability to resolve colocalization in components of small organelles such as the nucleus.
Abstract: An important step in three-dimensional reconstruction
and computer vision is camera calibration, whose objective is to
estimate the intrinsic and extrinsic parameters of each camera. In this
paper, two linear methods based on the different planes are given. In
both methods, the general plane is used to replace the calibration
object with very good precision. In the first method, after controlling
the camera to undergo five times- translation movements and taking
pictures of the orthogonal planes, a set of linear constraints of the
camera intrinsic parameters is then derived by means of homography
matrix. The second method is to get all camera parameters by taking
only one picture of a given radius circle. experiments on simulated
data and real images,indicate that our method is reasonable and is a
good supplement to camera calibration.
Abstract: Photoplethysmography is a simple measurement of the
variation in blood volume in tissue. It detects the pulse signal of heart
beat as well as the low frequency signal of vasoconstriction and
vasodilation. The transmission type measurement is limited to only a
few specific positions for example the index finger that have a short
path length for light. The reflectance type measurement can be
conveniently applied on most parts of the body surface. This study
analyzed the factors that determine the quality of reflectance
photoplethysmograph signal including the emitter-detector distance,
wavelength, light intensity, and optical properties of skin tissue.
Light emitting diodes (LEDs) with four different visible
wavelengths were used as the light emitters. A phototransistor was
used as the light detector. A micro translation stage adjusts the
emitter-detector distance from 2 mm to 15 mm.
The reflective photoplethysmograph signals were measured on
different sites. The optimal emitter-detector distance was chosen to
have a large dynamic range for low frequency drifting without signal
saturation and a high perfusion index. Among these four wavelengths,
a yellowish green (571nm) light with a proper emitter-detection
distance of 2mm is the most suitable for obtaining a steady and reliable
reflectance photoplethysmograph signal
Abstract: This article addresses the procedures to validate the Arabic version of Multiple Intelligence Development Assessment Scale (MIDAS). The content validity was examined based on the experts- judgments on the MIDAS-s items in the Arabic version. The content of eleven items in the Arabic version of MIDAS was modified to match the Arabic context. Then a translation from original English version of MIDAS into Arabic language was performed. The reliability of the Arabic MIDAS was calculated based on test and retest method and found to be 0.85 for the overall MIDAS and for the different subscales ranging between 0.78 - 0.87. The examination of construct validity for the overall Arabic MIDAS and its subscales was established by using Winsteps program version 6 based on Rasch model in order to fit the items into the Arabic context. The findings indicated that, the eight subscales in Arabic version of MIDAS scale have a unidimensionality, and the total number of kept items in the overall scale is 108 items.
Abstract: Selecting the word translation from a set of target
language words, one that conveys the correct sense of source word
and makes more fluent target language output, is one of core
problems in machine translation. In this paper we compare the 3
methods of estimating word translation probabilities for selecting the
translation word in Thai – English Machine Translation. The 3
methods are (1) Method based on frequency of word translation, (2)
Method based on collocation of word translation, and (3) Method
based on Expectation Maximization (EM) algorithm. For evaluation
we used Thai – English parallel sentences generated by NECTEC.
The method based on EM algorithm is the best method in comparison
to the other methods and gives the satisfying results.
Abstract: Random Access Memory (RAM) is an important
device in computer system. It can represent the snapshot on how the
computer has been used by the user. With the growth of its
importance, the computer memory has been an issue that has been
discussed in digital forensics. A number of tools have been developed
to retrieve the information from the memory. However, most of the
tools have their limitation in the ability of retrieving the important
information from the computer memory. Hence, this paper is aimed
to discuss the limitation and the setback for two main techniques such
as process signature search and process enumeration. Then, a new
hybrid approach will be presented to minimize the setback in both
individual techniques. This new approach combines both techniques
with the purpose to retrieve the information from the process block
and other objects in the computer memory. Nevertheless, the basic
theory in address translation for x86 platforms will be demonstrated
in this paper.
Abstract: The primary objective of this paper was to construct a
“kinematic parameter-independent modeling of three-axis machine
tools for geometric error measurement" technique. Improving the
accuracy of the geometric error for three-axis machine tools is one of
the machine tools- core techniques. This paper first applied the
traditional method of HTM to deduce the geometric error model for
three-axis machine tools. This geometric error model was related to the
three-axis kinematic parameters where the overall errors was relative
to the machine reference coordinate system. Given that the
measurement of the linear axis in this model should be on the ideal
motion axis, there were practical difficulties. Through a measurement
method consolidating translational errors and rotational errors in the
geometric error model, we simplified the three-axis geometric error
model to a kinematic parameter-independent model. Finally, based on
the new measurement method corresponding to this error model, we
established a truly practical and more accurate error measuring
technique for three-axis machine tools.