Abstract: Oxidative stress makes up common incidents in
eukaryotic metabolism. The presence of diverse components
disturbing the equilibrium during oxygen metabolism increases
oxidative damage unspecifically in living cells. Body´s own
ubiquinone (Q10) seems to be a promising drug in defending the
heightened appearance of reactive oxygen species (ROS). Though, its
lipophilic properties require a new strategy in drug formulation to
overcome their low bioavailability. Consequently, the manufacture of
heterogeneous nanodispersions is in focus for medical applications.
The composition of conventional nanodispersions is made up of a
drug-consisting core and a surfactive agent, also named as surfactant.
Long-termed encapsulation of the surfactive components into tissues
might be the consequence of the use during medical therapeutics. The
potential of provoking side-effects is given by their nonbiodegradable
properties. Further improvements during fabrication
process use the incorporation of biodegradable components such as
modified γ-polyglutamic acid which decreases the potential of
prospective side-effects.
Abstract: Policies that support entrepreneurship are keys to the
generation of new business. In Brazil, seed capital, installation of
technology parks, programs and zero interest financing, economic
subsidy as Program First Innovative Company (PRIME) are
examples of incentive policies. For the implementation of PRIME, in
particular the Brazilian Innovation Agency (FINEP) decentralized
operationalization so that business incubators could select innovative
projects. This paper analyzes the program PRIME Business Incubator
Center of the State of Sergipe (CISE) after calculating the mean and
standard deviation of the grades obtained by companies in the factors
of innovation, market potential, financial return economic, market
strategy and staff and application of the Mann-Whitney test.
Abstract: Rural villagers in Thailand have unique skill for producing craft using local materials. However, the appearance and function of their products are not suited to the demand of international market. The Thai government policy on sustainable economy emphasises the necessity to incorporate a design strategy that will draw out the unique qualities and add value to the products, while raising the satisfaction of international consumer. As an industrial designer, the author sees opportunities that design can enhance sustainability of Thai local products through the potentials that available in village-based enterprises. This research attempts to address, how best use design to practically solve the problems in the development of Thais product in. The privilege solution is expressed through the design of design strategy that supports sustain economic development of microenterprise in Thailand in the way that aligns with product design development. This consideration integrates together with global business outlook in the development of products from rural communities.
Abstract: Omni directional mobile robots have been popularly
employed in several applications especially in soccer player robots
considered in Robocup competitions. However, Omni directional
navigation system, Omni-vision system and solenoid kicking
mechanism in such mobile robots have not ever been combined. This
situation brings the idea of a robot with no head direction into
existence, a comprehensive Omni directional mobile robot. Such a
robot can respond more quickly and it would be capable for more
sophisticated behaviors with multi-sensor data fusion algorithm for
global localization base on the data fusion. This paper has tried to
focus on the research improvements in the mechanical, electrical and
software design of the robots of team ADRO Iran. The main
improvements are the world model, the new strategy framework,
mechanical structure, Omni-vision sensor for object detection, robot
path planning, active ball handling mechanism and the new kicker
design, , and other subjects related to mobile robot
Abstract: The implicit block methods based on the backward
differentiation formulae (BDF) for the solution of stiff initial value
problems (IVPs) using variable step size is derived. We construct a
variable step size block methods which will store all the coefficients
of the method with a simplified strategy in controlling the step size
with the intention of optimizing the performance in terms of
precision and computation time. The strategy involves constant,
halving or increasing the step size by 1.9 times the previous step size.
Decision of changing the step size is determined by the local
truncation error (LTE). Numerical results are provided to support the
enhancement of method applied.
Abstract: In the LFC problem, the interconnections among some areas are the input of disturbances, and therefore, it is important to suppress the disturbances by the coordination of governor systems. In contrast, tie-line power flow control by TCPS located between two areas makes it possible to stabilize the system frequency oscillations positively through interconnection, which is also expected to provide a new ancillary service for the further power systems. Thus, a control strategy using controlling the phase angle of TCPS is proposed for provide active control facility of system frequency in this paper. Also, the optimum adjustment of PID controller's parameters in a robust way under bilateral contracted scenario following the large step load demands and disturbances with and without TCPS are investigated by Particle Swarm Optimization (PSO), that has a strong ability to find the most optimistic results. This newly developed control strategy combines the advantage of PSO and TCPS and has simple stricture that is easy to implement and tune. To demonstrate the effectiveness of the proposed control strategy a three-area restructured power system is considered as a test system under different operating conditions and system nonlinearities. Analysis reveals that the TCPS is quite capable of suppressing the frequency and tie-line power oscillations effectively as compared to that obtained without TCPS for a wide range of plant parameter changes, area load demands and disturbances even in the presence of system nonlinearities.
Abstract: The IDR(s) method based on an extended IDR theorem was proposed by Sonneveld and van Gijzen. The original IDR(s) method has excellent property compared with the conventional iterative methods in terms of efficiency and small amount of memory. IDR(s) method, however, has unexpected property that relative residual 2-norm stagnates at the level of less than 10-12. In this paper, an effective strategy for stagnation detection, stagnation avoidance using adaptively information of parameter s and improvement of convergence rate itself of IDR(s) method are proposed in order to gain high accuracy of the approximated solution of IDR(s) method. Through numerical experiments, effectiveness of adaptive tuning IDR(s) method is verified and demonstrated.
Abstract: Evolvable hardware (EHW) refers to a selfreconfiguration
hardware design, where the configuration is under
the control of an evolutionary algorithm (EA). A lot of research has
been done in this area several different EA have been introduced.
Every time a specific EA is chosen for solving a particular problem,
all its components, such as population size, initialization, selection
mechanism, mutation rate, and genetic operators, should be selected
in order to achieve the best results. In the last three decade a lot of
research has been carried out in order to identify the best parameters
for the EA-s components for different “test-problems". However
different researchers propose different solutions. In this paper the
behaviour of mutation rate on (1+λ) evolution strategy (ES) for
designing logic circuits, which has not been done before, has been
deeply analyzed. The mutation rate for an EHW system modifies
values of the logic cell inputs, the cell type (for example from AND
to NOR) and the circuit output. The behaviour of the mutation has
been analyzed based on the number of generations, genotype
redundancy and number of logic gates used for the evolved circuits.
The experimental results found provide the behaviour of the mutation
rate to be used during evolution for the design and optimization of
logic circuits. The researches on the best mutation rate during the last
40 years are also summarized.
Abstract: The main objective of this study was to demonstrate that differentiation of infected and vaccinated animals (DIVA) strategy using different ELISA tests is possible when a subunit vaccine (Haemagglutinin protein) is used to prevent Avian influenza. Special emphasis was placed on the differentiation in the serological response to different components of the AIV (Nucleoprotein, Neuraminidase, Haemagglutinin, Nucleocapsid) between chickens that were vaccinated with a whole virus kill vaccine and recombinant vaccine. Furthermore, the potential use of this DIVA strategy using ELISA assays to detect Neuraminidase 1 (N1) was analyzed as strategy in countries where the field virus is H5N1 and the vaccine used is formulated with H5N2. Detection of AIV-s antibodies to any component in serum was negative for all animals on the study days 0-13. At study day 14 the titers of antibodies against Nucleoprotein (NP) and Nucleocapsid (NC) rose in the experimental groups vaccinated with Volvac® AI KV and were negatives during all the trial in the experimental groups vaccinated with a subunit H5; significant statistically differences were observed between these groups (p < 0.05). The seroconversion either Haemagglutinin or Neuraminidase was evident after 21 days post-vaccination in the experimental groups vaccinated with the respective viral fraction. Regarding the main aim of this study and according with the results that were obtained, use a combination of different ELISA test as a DIVA strategy is feasible when the vaccination is carry out with a subunit H5 vaccine. Also is possible to use the ELISA kit to detect Neuraminidase (either N1 or N2) as a DIVA concept in countries where H5N1 is present and the vaccination programs are done with H5N2 vaccine.
Abstract: This work is focused on the numerical prediction of the fracture resistance of a flat stiffened panel made of the aluminium alloy 2024 T3 under a monotonic traction condition. The performed numerical simulations have been based on the micromechanical Gurson-Tvergaard (GT) model for ductile damage. The applicability of the GT model to this kind of structural problems has been studied and assessed by comparing numerical results, obtained by using the WARP 3D finite element code, with experimental data available in literature. In the sequel a home-made procedure is presented, which aims to increase the residual strength of a cracked stiffened aluminum panel and which is based on the stochastic design improvement (SDI) technique; a whole application example is then given to illustrate the said technique.
Abstract: According to the density of the chips, designers are
trying to put so any facilities of computational and storage on single
chips. Along with the complexity of computational and storage
circuits, the designing, testing and debugging become more and more
complex and expensive. So, hardware design will be built by using
very high speed hardware description language, which is more
efficient and cost effective. This paper will focus on the
implementation of 32-bit ALU design based on Verilog hardware
description language. Adder and subtracter operate correctly on both
unsigned and positive numbers. In ALU, addition takes most of the
time if it uses the ripple-carry adder. The general strategy for
designing fast adders is to reduce the time required to form carry
signals. Adders that use this principle are called carry look- ahead
adder. The carry look-ahead adder is to be designed with combination
of 4-bit adders. The syntax of Verilog HDL is similar to the C
programming language. This paper proposes a unified approach to
ALU design in which both simulation and formal verification can
co-exist.
Abstract: The purpose is to study the model and characteristic of
participation of the suitable community to lead to develop permanent
water marketing in Bang Noi Floating Market, Bangkonti District,
Samutsongkhram Province. A total of 342 survey questionnaire was
administered to potential respondents. The researchers interviewed
the leader of the community. Appreciation Influence Control (AIC)
was used to talk with 20 villagers on arena. The findings revealed
that overall, most people had the middle level of the participation in
developing the durable Bang Noi Floating Market, Bangkonti,
Samutsongkhram Province and in aspects of gaining benefits from
developing it with atmosphere and a beautiful view for tourism. For
example, the landscape is beautiful with public utilities. The
participation in preserving and developing Bang Noi Floating Market
remains in the former way of life. The basic factor of person affects
to the participation of people such as age, level of education, career,
and income per month. Most participants are the original hosts that
have houses and shops located in the marketing and neighbor. These
people involve with the benefits and have the power to make a water
marketing strategy, the major role to set the information database. It
also found that the leader and the villagers play the important role in
setting a five-physical database. Data include level of information
such as position of village, territory of village, road, river, and
premises. Information of culture consists of a two-level of
information, interesting point, and Itinerary. The information occurs
from presenting and practicing by the leader and villagers in the
community.All of phases are presented for listening and investigating
database together in both the leader and villagers in the process of
participation.
Abstract: Biological evolution has generated a rich variety of
successful solutions; from nature, optimized strategies can be
inspired. One interesting example is the ant colonies, which are able
to exhibit a collective intelligence, still that their dynamic is simple.
The emergence of different patterns depends on the pheromone trail,
leaved by the foragers. It serves as positive feedback mechanism for
sharing information.
In this paper, we use the dynamic of TASEP as a model of
interaction at a low level of the collective environment in the ant-s
traffic flow. This work consists of modifying the movement rules of
particles “ants" belonging to the TASEP model, so that it adopts with
the natural movement of ants. Therefore, as to respect the constraints
of having no more than one particle per a given site, and in order to
avoid collision within a bidirectional circulation, we suggested two
strategies: decease strategy and waiting strategy. As a third work
stage, this is devoted to the study of these two proposed strategies-
stability. As a final work stage, we applied the first strategy to the
whole environment, in order to get to the emergence of traffic flow,
which is a way of learning.
Abstract: In a wind power generator using doubly fed induction
generator (DFIG), the three-phase pulse width modulation (PWM)
voltage source converter (VSC) is used as grid side converter (GSC)
and rotor side converter (RSC). The standard linear control laws
proposed for GSC provides not only instablity against comparatively
large-signal disturbances, but also the problem of stability due to
uncertainty of load and variations in parameters. In this paper, a
nonlinear controller is designed for grid side converter (GSC) of a
DFIG for wind power application. The nonlinear controller is
designed based on the input-output feedback linearization control
method. The resulting closed-loop system ensures a sufficient
stability region, make robust to variations in circuit parameters and
also exhibits good transient response. Computer simulations and
experimental results are presented to confirm the effectiveness of the
proposed control strategy.
Abstract: In this paper an efficient incomplete factorization preconditioner is proposed for the Least Mean Squares (LMS) adaptive filter. The proposed preconditioner is approximated from a priori knowledge of the factors of input correlation matrix with an incomplete strategy, motivated by the sparsity patter of the upper triangular factor in the QRD-RLS algorithm. The convergence properties of IPLMS algorithm are comparable with those of transform domain LMS(TDLMS) algorithm. Simulation results show efficiency and robustness of the proposed algorithm with reduced computational complexity.
Abstract: The improvement of quality of life is the main visible
integrated indicator of state well-being. More and more states pay
attention to define and to achieve social standards of quality of life as
social-economic strategy of development. These standards are
determinate by state features, complex of needs and interests of
individual, family and society.
It still remains in open question: “What is middle class" in
contemporary Kazakhstan. Appearance of new social standards of
quality of life is important indicator of its successful establishment.
The middle class as agent of social, politic and economic reforms
promotes to improve the quality of life of the country. But if consider
a low and a middle stratums of middle class, we can see that high
social expectations and real achievements are still significantly
different.
The article relies on the sociological data, collected during of
search of household-s standards of living in Almaty city and Almaty
region, and case-study of cottage city “Jana Kuat".
Abstract: Current trends in manufacturing are characterized by
production broadening, innovation cycle shortening, and the products
having a new shape, material and functions. The production strategy
focused on time needed change from the traditional functional
production structure to flexible manufacturing cells and lines.
Production by automated manufacturing system (AMS) is one of the
most important manufacturing philosophies in the last years. The
main goals of the project we are involved in lies on building a
laboratory in which will be located a flexible manufacturing system
consisting of at least two production machines with NC control
(milling machines, lathe). These machines will be linked to a
transport system and they will be served by industrial robots. Within
this flexible manufacturing system a station for the quality control
consisting of a camera system and rack warehouse will be also
located. The design, analysis and improvement of this manufacturing
system, specially with a special focus on the communication among
devices constitute the main aims of this paper. The key determining
factors for the manufacturing system design are: the product, the
production volume, the used machines, the disposable manpower, the
disposable infrastructure and the legislative frame for the specific
cases.
Abstract: This paper will focus on modeling, analysis and simulation of a 42V/14V dc/dc converter based architecture. This architecture is considered to be technically a viable solution for automotive dual-voltage power system for passenger car in the near further. An interleaved dc/dc converter system is chosen for the automotive converter topology due to its advantages regarding filter reduction, dynamic response, and power management. Presented herein, is a model based on one kilowatt interleaved six-phase buck converter designed to operate in a Discontinuous Conduction Mode (DCM). The control strategy of the converter is based on a voltagemode- controlled Pulse Width Modulation (PWM) with a Proportional-Integral-Derivative (PID). The effectiveness of the interleaved step-down converter is verified through simulation results using control-oriented simulator, MatLab/Simulink.
Abstract: A semi-active control strategy for suspension
systems of passenger cars is presented employing
Magnetorheological (MR) dampers. The vehicle is modeled with
seven DOFs including the, roll pitch and bounce of car body, and
the vertical motion of the four tires. In order to design an optimal
controller based on the actuator constraints, a Linear-Quadratic
Regulator (LQR) is designed. The design procedure of the LQR
consists of selecting two weighting matrices to minimize the energy
of the control system. This paper presents a hybrid optimization
procedure which is a combination of gradient-based and
evolutionary algorithms to choose the weighting matrices with
regards to the actuator constraint. The optimization algorithm is
defined based on maximum comfort and actuator constraints. It is
noted that utilizing the present control algorithm may significantly
reduce the vibration response of the passenger car, thus, providing
a comfortable ride.
Abstract: A subjectively influenced router for vehicles in a fourjunction
traffic system is presented. The router is based on a 3-layer
Backpropagation Neural Network (BPNN) and a greedy routing
procedure. The BPNN detects priorities of vehicles based on the
subjective criteria. The subjective criteria and the routing procedure
depend on the routing plan towards vehicles depending on the user.
The routing procedure selects vehicles from their junctions based on
their priorities and route them concurrently to the traffic system. That
is, when the router is provided with a desired vehicles selection
criteria and routing procedure, it routes vehicles with a reasonable
junction clearing time. The cost evaluation of the router determines
its efficiency. In the case of a routing conflict, the router will route
the vehicles in a consecutive order and quarantine faulty vehicles.
The simulations presented indicate that the presented approach is an
effective strategy of structuring a subjective vehicle router.