Design of Salbutamol Sulphate Gastroretentive Nanoparticles via Surface Charge Manipulation

In the present study, development of salbutamol sulphate nanoparticles that adhere to gastric mucus was investigated. Salbutamol sulphate has low bioavailability due to short transit time in gastric. It also has a positive surface charge that provides hurdles to be encapsulated by the positively strong mucoadhesive polymer of chitosan. To overcome the difficulties, the surface charge of active ingredient was modified using several nonionic and anionic stomach-specific polymers. The nanoparticles were prepared using ionotropic gelation technique. The evaluation involved determination of particle size, zeta potential, entrapment efficiency, in vitro drug release and in vitro mucoadhesion test. Results exhibited that the use of anionic alginate polymer was more satisfactory than that of nonionic polymer. Characteristics of the particles was nano-size, high encapsulation efficiency, fulfilled the drug release requirements and adhesive towards stomach for around 11 hours. This result shows that the salbutamol sulphate nanoparticles can be utilized for improvement its delivery.

Overviews of Rainwater Harvesting and Utilization in Thailand: Bangsaiy Municipality

In developing countries located in monsoon areas like Thailand where rainwater is currently of no value for urban dwellers due to easily access to piped water supply at each household, studies in rainwater harvesting for domestic use are of low interest. However it is needed to undertake research to find out appropriate rainwater harvesting systems particularly for small urban communities that are recently developed from a full rural structure to urban context. As a matter of fact, in such transitional period, relying on only common water resources is risky. With some specific economic settings, land use patterns, and historical and cultural context that dominate perceptions of water users in the study area, the level of service in this study may certainly be different from megacities or cities located in industrial zone. The overviews of some available technologies and background of rainwater harvesting including alternate resource are included in this paper. Among other sources of water supply, ground water use as the water resource of Thailand and also in the study area.

Thermal Stability and Crystallization Behaviour of Modified ABS/PP Nanocomposites

In this research work, poly (acrylonitrile-butadienestyrene)/ polypropylene (ABS/PP) blends were processed by melt compounding in a twin-screw extruder. Upgrading of the thermal characteristics of the obtained materials was attempted by the incorporation of organically modified montmorillonite (OMMT), as well as, by the addition of two types of compatibilizers; polypropylene grafted with maleic anhydride (PP-g-MAH) and ABS grafted with maleic anhydride (ABS-g-MAH). The effect of the above treatments was investigated separately and in combination. Increasing the PP content in ABS matrix seems to increase the thermal stability of their blend and the glass transition temperature (Tg) of SAN phase of ABS. From the other part, the addition of ABS to PP promotes the formation of its β-phase, which is maximum at 30 wt% ABS concentration, and increases the crystallization temperature (Tc) of PP. In addition, it increases the crystallization rate of PP.The β-phase of PP in ABS/PP blends is reduced by the addition of compatibilizers or/and organoclay reinforcement. The incorporation of compatibilizers increases the thermal stability of PP and reduces its melting (ΔΗm) and crystallization (ΔΗc) enthalpies. Furthermore it decreases slightly the Tgs of PP and SAN phases of ABS/PP blends. Regarding the storage modulus of the ABS/PP blends, it presents a change in their behavior at about 10°C and return to their initial behavior at ~110°C. The incorporation of OMMT to no compatibilized and compatibilized ABS/PP blends enhances their storage modulus.

How to Win Passengers and Influence Motorists? Lessons Learned from a Comparative Study of Global Transit Systems

Due to the call of global warming effects, city planners aim at actions for reducing carbon emission. One of the approaches is to promote the usage of public transportation system toward the transit-oriented-development. For example, rapid transit system in Taipei city and Kaohsiung city are opening. However, until November 2008 the average daily patronage counted only 113,774 passengers at Kaohsiung MRT systems, much less than which was expected. Now the crucial questions: how the public transport competes with private transport? And more importantly, what factors would enhance the use of public transport? To give the answers to those questions, our study first applied regression to analyze the factors attracting people to use public transport around cities in the world. It is shown in our study that the number of MRT stations, city population, cost of living, transit fare, density, gasoline price, and scooter being a major mode of transport are the major factors. Subsequently, our study identified successful and unsuccessful cities in regard of the public transport usage based on the diagnosis of regression residuals. Finally, by comparing transportation strategies adopted by those successful cities, our conclusion stated that Kaohsiung City could apply strategies such as increasing parking fees, reducing parking spaces in downtown area, and reducing transfer time by providing more bus services and public bikes to promote the usage of public transport.

Performance Analysis of Quantum Cascaded Lasers

Improving the performance of the QCL through block diagram as well as mathematical models is the main scope of this paper. In order to enhance the performance of the underlined device, the mathematical model parameters are used in a reliable manner in such a way that the optimum behavior was achieved. These parameters play the central role in specifying the optical characteristics of the considered laser source. Moreover, it is important to have a large amount of radiated power, where increasing the amount of radiated power represents the main hopping process that can be predicted from the behavior of quantum laser devices. It was found that there is a good agreement between the calculated values from our mathematical model and those obtained with VisSim and experimental results. These demonstrate the strength of mplementation of both mathematical and block diagram models.

Modeling User Behaviour by Planning

A model of user behaviour based automated planning is introduced in this work. The behaviour of users of web interactive systems can be described in term of a planning domain encapsulating the timed actions patterns representing the intended user profile. The user behaviour recognition is then posed as a planning problem where the goal is to parse a given sequence of user logs of the observed activities while reaching a final state. A general technique for transforming a timed finite state automata description of the behaviour into a numerical parameter planning model is introduced. Experimental results show that the performance of a planning based behaviour model is effective and scalable for real world applications. A major advantage of the planning based approach is to represent in a single automated reasoning framework problems of plan recognitions, plan synthesis and plan optimisation.

Application of Formal Methods for Designing a Separation Kernel for Embedded Systems

A separation-kernel-based operating system (OS) has been designed for use in secure embedded systems by applying formal methods to the design of the separation-kernel part. The separation kernel is a small OS kernel that provides an abstract distributed environment on a single CPU. The design of the separation kernel was verified using two formal methods, the B method and the Spin model checker. A newly designed semi-formal method, the extended state transition method, was also applied. An OS comprising the separation-kernel part and additional OS services on top of the separation kernel was prototyped on the Intel IA-32 architecture. Developing and testing of a prototype embedded application, a point-of-sale application, on the prototype OS demonstrated that the proposed architecture and the use of formal methods to design its kernel part are effective for achieving a secure embedded system having a high-assurance separation kernel.

Knowledge Modelling for a Hotel Recommendation System

Knowledge modelling, a main activity for the development of Knowledge Based Systems, have no set standards and are mostly done in an ad hoc way. There is a lack of support for the transition from abstract level to implementation. In this paper, a methodology for the development of the knowledge model, which is inspired by both Software and Knowledge Engineering, is proposed. Use of UML which is the de-facto standard for modelling in the software engineering arena is explored for knowledge modelling. The methodology proposed, is used to develop a knowledge model of a knowledge based system for recommending suitable hotels for tourists visiting Mauritius.

Interactive Model Based On an Extended CPN

The UML modeling of complex distributed systems often is a great challenge due to the large amount of parallel real-time operating components. In this paper the problems of verification of such systems are discussed. ECPN, an Extended Colored Petri Net is defined to formally describe state transitions of components and interactions among components. The relationship between sequence diagrams and Free Choice Petri Nets is investigated. Free Choice Petri Net theory helps verifying the liveness of sequence diagrams. By converting sequence diagrams to ECPNs and then comparing behaviors of sequence diagram ECPNs and statecharts, the consistency among models is analyzed. Finally, a verification process for an example model is demonstrated.

Assessing Land Cover Change Trajectories in Olomouc, Czech Republic

Olomouc is a unique and complex landmark with widespread forestation and land use. This research work was conducted to assess important and complex land use change trajectories in Olomouc region. Multi-temporal satellite data from 1991, 2001 and 2013 were used to extract land use/cover types by object oriented classification method. To achieve the objectives, three different aspects were used: (1) Calculate the quantity of each transition; (2) Allocate location based landscape pattern (3) Compare land use/cover evaluation procedure. Land cover change trajectories shows that 16.69% agriculture, 54.33% forest and 21.98% other areas (settlement, pasture and water-body) were stable in all three decade. Approximately 30% of the study area maintained as a same land cove type from 1991 to 2013. Here broad scale of political and socioeconomic factors was also affect the rate and direction of landscape changes. Distance from the settlements was the most important predictor of land cover change trajectories. This showed that most of landscape trajectories were caused by socio-economic activities and mainly led to virtuous change on the ecological environment.

Manufacturers-Retailers: The New Actor in the U.S. Furniture Industry. Characteristics and Implications for the Chinese Furniture Industry

Since the 1990s the American furniture industry faces a transition period. Manufacturers, one of its most important actors made its entrance into the retail industry. This shift has had deep consequences not only for the American furniture industry as a whole, but also for other international furniture industries, especially the Chinese. The present work aims to analyze this actor based on the distinction provided by the Global Commodity Chain Theory. It stresses its characteristics, structure, operational way and importance for both the U.S. and the Chinese furniture industries.

Unsteady Laminar Boundary Layer Forced Flow in the Region of the Stagnation Point on a Stretching Flat Sheet

This paper analyses the unsteady, two-dimensional stagnation point flow of an incompressible viscous fluid over a flat sheet when the flow is started impulsively from rest and at the same time, the sheet is suddenly stretched in its own plane with a velocity proportional to the distance from the stagnation point. The partial differential equations governing the laminar boundary layer forced convection flow are non-dimensionalised using semi-similar transformations and then solved numerically using an implicit finitedifference scheme known as the Keller-box method. Results pertaining to the flow and heat transfer characteristics are computed for all dimensionless time, uniformly valid in the whole spatial region without any numerical difficulties. Analytical solutions are also obtained for both small and large times, respectively representing the initial unsteady and final steady state flow and heat transfer. Numerical results indicate that the velocity ratio parameter is found to have a significant effect on skin friction and heat transfer rate at the surface. Furthermore, it is exposed that there is a smooth transition from the initial unsteady state flow (small time solution) to the final steady state (large time solution).

Transmission Mains Earthing Design: Under Ground to Over Head Pole Transition

The demand on High voltage (HV) infrastructures is growing due to the corresponding growth in industries and population. New or upgraded HV infrastructure has safety implications since Transmission mains usually occupy the same easement in the vicinity of neighbouring residents. Transmission mains consist of underground (UG) and overhead (OH) sections and the transition between the UG and OH section is known as the UGOH pole. The existence of two transmission mains in the same easement can dictate to resort to more complicated earthing design in order to mitigate the effect of AC interference, and in some cases it can also necessitates completing a Split Study of the system. This paper provides an overview of the AC interference, Split Study and the earthing of an underground feeder including the UGOH pole .In addition, this paper discusses the use of different link boxes on the UG feeder and presents a case study that represent a clear example of the Ac interference and Split factor. Finally, a few recommendations are provided to achieve a safety zone in the area beyond the boundary of the HV system.

Intelligent BRT in Tehran

an intelligent BRT system is necessary when communities looking for new ways to use high capacity rapid transit at a reduced cost.This paper will describe the intelligent control system that works with Datacenter. With the help of GPS system, the data center can monitor the situation of each bus and bus station. Through RFID technology, bus station and traffic light can transfer data with bus and by Wimax communication technology all of parts can talk together; data center learns all information about the location of bus, the arrival of bus in each station and the number of passengers in station and bus.Finally, the paper presents the case study of those theories in Tehran BRT.

Congo Red Photocatalytic Decolourization using Modified Titanium

A study concerning the photocatalytic decolourization of Congo red (CR) dye, over artificial UV irradiation is presented. Photocatalysts based on a commercial titanium dioxide (TiO2) modified with transition metals (Ni, Cu and Zn) were used. The dopage method used was wet impregnation. A TiO2 sample without salt was subjected to the same hydrothermal treatment to be used as reference. Congo red solutions to several pH conditions (natural and basic) were used to evaluate photocatalytic performance of each doped catalysts. Photodecolourization percentage was measured spectrofotrometically after 3 h of treatment to 499 nm as response variable. Kinetics investigations of photodegradation indicated that reactions obey to Langmuir-Hinshelwood model and pseudo–first order law. The rate constant studies of photocatalytic decolourization reactions for Zn–TiO2 and Cu–TiO2 photocatalysts indicated that in all cases the rate constant of the reaction was higher than that of TiO2 undoped. These results show that nature of the metal modifying the TiO2 influence on the efficiency of the photocatalyst evaluated in process. Ni does not present an additional effect compared with TiO2, while Zn enhances the photoactivity due to its electronic properties.

Perceived Constraints on Sport Participation among Young Koreans in Australia

The purpose of this study was to examine a broader range of sport constraints perceived by young Koreans in Australia who may need to adjust to changing behavioral expectations due to the socio-cultural transitions. Regardless of gender, in terms of quantitative findings, the most important participation constraints within the seven categories were resources, access, interpersonal, affective, religious, socio-cultural, and physical in that order. The most important constraining items were a lack of time, access, information, adaptive skills, and parental and family support in that order. Qualitative research found young Korean’s participation constraints among three categories (time, parental control and interpersonal constraints). It is possible that different ethnic groups would be constrained by different factors; however, this is outside the scope of this study.

Abai Kunanbayev's Role in Enrichment of the Kazakh Language

Abai Kunanbayev is famous for being enlightener, composer, interpreter, social agent, philosopher, reformer, who wanted to enrich Kazakh literature by emergence with Russian and European culture, and also as a founder of Kazakh written literary language. Abai Kunanbayev was born in 1845 in East Kazakhstan area and passed away in 1904 in his hometown. His oeuvre absorbed and reflected all changes in the life of Kazakh society of the second half of XIX century. Because ХІХ century, especially its second half, was an important transition period for Kazakhstan, which radically changed traditional way of Kazakh society and predetermined further development in consequence of activation of Russian colonial policy and approval of commodity-money relations in Steppe Land.Abai Kunanbayev, besides Arabic and Persian common words and loanwords from Quran in his words of edification, had used a lot of words of Arabic, Persian, Latin, Russian, Nogai, Shaghatai, Polish, Greek, Turkish, which are used in the Kazakh language.

Development of Mechanical Properties of Self Compacting Concrete Contain Rice Husk Ash

Self-compacting concrete (SCC), a new kind of high performance concrete (HPC) have been first developed in Japan in 1986. The development of SCC has made casting of dense reinforcement and mass concrete convenient, has minimized noise. Fresh self-compacting concrete (SCC) flows into formwork and around obstructions under its own weight to fill it completely and self-compact (without any need for vibration), without any segregation and blocking. The elimination of the need for compaction leads to better quality concrete and substantial improvement of working conditions. SCC mixes generally have a much higher content of fine fillers, including cement, and produce excessively high compressive strength concrete, which restricts its field of application to special concrete only. To use SCC mixes in general concrete construction practice, requires low cost materials to make inexpensive concrete. Rice husk ash (RHA) has been used as a highly reactive pozzolanic material to improve the microstructure of the interfacial transition zone (ITZ) between the cement paste and the aggregate in self compacting concrete. Mechanical experiments of RHA blended Portland cement concretes revealed that in addition to the pozzolanic reactivity of RHA (chemical aspect), the particle grading (physical aspect) of cement and RHA mixtures also exerted significant influences on the blending efficiency. The scope of this research was to determine the usefulness of Rice husk ash (RHA) in the development of economical self compacting concrete (SCC). The cost of materials will be decreased by reducing the cement content by using waste material like rice husk ash instead of. This paper presents a study on the development of Mechanical properties up to 180 days of self compacting and ordinary concretes with rice-husk ash (RHA), from a rice paddy milling industry in Rasht (Iran). Two different replacement percentages of cement by RHA, 10%, and 20%, and two different water/cementicious material ratios (0.40 and 0.35), were used for both of self compacting and normal concrete specimens. The results are compared with those of the self compacting concrete without RHA, with compressive, flexural strength and modulus of elasticity. It is concluded that RHA provides a positive effect on the Mechanical properties at age after 60 days. Base of the result self compacting concrete specimens have higher value than normal concrete specimens in all test except modulus of elasticity. Also specimens with 20% replacement of cement by RHA have the best performance.

Transient Population Dynamics of Phase Singularities in 2D Beeler-Reuter Model

The paper presented a transient population dynamics of phase singularities in 2D Beeler-Reuter model. Two stochastic modelings are examined: (i) the Master equation approach with the transition rate (i.e., λ(n, t) = λ(t)n and μ(n, t) = μ(t)n) and (ii) the nonlinear Langevin equation approach with a multiplicative noise. The exact general solution of the Master equation with arbitrary time-dependent transition rate is given. Then, the exact solution of the mean field equation for the nonlinear Langevin equation is also given. It is demonstrated that transient population dynamics is successfully identified by the generalized Logistic equation with fractional higher order nonlinear term. It is also demonstrated the necessity of introducing time-dependent transition rate in the master equation approach to incorporate the effect of nonlinearity.

Pressure Study on Mn Doped KDP System under Hydrostatic Pressure

High Pressure Raman scattering measurements of KDP:Mn were performed at room temperatures. The X-ray powder diffraction patterns taken at room temperature by Rietveld refinement showed that doped samples of KDP-Mn have the same tetragonal structure of a pure KDP crystal, but with a contraction of the crystalline cell. The behavior of the Raman spectra, in particular the emergence of a new modes at 330 cm-1, indicates that KDP:Mn undergoes a structural phase transition with onset at around 4 GP. First principle density-functional theory (DFT) calculations indicate that tetrahedral rotation with pressure is predominantly around the c crystalline direction. Theoretical results indicates that pressure induced tetrahedral rotations leads to change tetrahedral neighborhood, activating librations/bending modes observed for high pressure phase of KDP:Mn with stronger Raman activity.