Abstract: Rapid Prototyping (RP) is a technology that produces models and prototype parts from 3D CAD model data, CT/MRI scan data, and model data created from 3D object digitizing systems. There are several RP process like Stereolithography (SLA), Solid Ground Curing (SGC), Selective Laser Sintering (SLS), Fused Deposition Modeling (FDM), 3D Printing (3DP) among them SLS and FDM RP processes are used to fabricate pattern of custom cranial implant. RP technology is useful in engineering and biomedical application. This is helpful in engineering for product design, tooling and manufacture etc. RP biomedical applications are design and development of medical devices, instruments, prosthetics and implantation; it is also helpful in planning complex surgical operation. The traditional approach limits the full appreciation of various bony structure movements and therefore the custom implants produced are difficult to measure the anatomy of parts and analyze the changes in facial appearances accurately. Cranioplasty surgery is a surgical correction of a defect in cranial bone by implanting a metal or plastic replacement to restore the missing part. This paper aims to do a comparative study on the dimensional error of CAD and SLS RP Models for reconstruction of cranial defect by comparing the virtual CAD with the physical RP model of a cranial defect.
Abstract: Images are important in disease research, education,
and clinical medicine. This paper presents a Web Service Platform
(WSP) for support multiple programming languages to access image
from biomedical databases. The main function WSP is to allow web
users access image from biomedical databases. The WSP will
receive web user-s queries. After that, it will send to Querying
Server (QS) and the QS will search and retrieve data from
biomedical databases. Finally, the information will display to the
web users. Simple application is developed and tested for
experiment purpose. Result from experiment indicated WSP can be
used in biomedical environment.
Abstract: One of the essential requirements in order to have a
realistic surgical simulator is real-time interaction by means of a
haptic interface is. In fact, reproducing haptic sensations increases
the realism of the simulation. However, the interaction need to be
performed in real-time, since a delay between the user action and the
system reaction reduces the user immersion. In this paper, we present
a prototype of the coronary stent implant simulator developed in the
HERMES Project; this system allows real-time interactions with a
artery by means of a specific haptic device; thus the user can
interactively navigate in a reconstructed artery and force feedback is
produced when contact occurs between the artery walls and the
medical instruments
Abstract: In this paper, computational fluid dynamics (CFD) is utilized to characterize a prototype biolistic delivery system, the biomedical device based on the contoured-shock-tube design (CST), with the aim at investigating shocks induced flow instabilities within the contoured shock tube. The shock/interface interactions, the growth of perturbation at an interface between two fluids of different density are interrogated. The key features of the gas dynamics and gas-particle interaction are discussed
Abstract: The counting and analysis of blood cells allows the
evaluation and diagnosis of a vast number of diseases. In particular,
the analysis of white blood cells (WBCs) is a topic of great interest to
hematologists. Nowadays the morphological analysis of blood cells is
performed manually by skilled operators. This involves numerous
drawbacks, such as slowness of the analysis and a nonstandard
accuracy, dependent on the operator skills. In literature there are only
few examples of automated systems in order to analyze the white
blood cells, most of which only partial. This paper presents a
complete and fully automatic method for white blood cells
identification from microscopic images. The proposed method firstly
individuates white blood cells from which, subsequently, nucleus and
cytoplasm are extracted. The whole work has been developed using
MATLAB environment, in particular the Image Processing Toolbox.
Abstract: Deformable active contours are widely used in
computer vision and image processing applications for image
segmentation, especially in biomedical image analysis. The active
contour or “snake" deforms towards a target object by controlling the
internal, image and constraint forces. However, if the contour
initialized with a lesser number of control points, there is a high
probability of surpassing the sharp corners of the object during
deformation of the contour. In this paper, a new technique is
proposed to construct the initial contour by incorporating prior
knowledge of significant corners of the object detected using the
Harris operator. This new reconstructed contour begins to deform, by
attracting the snake towards the targeted object, without missing the
corners. Experimental results with several synthetic images show the
ability of the new technique to deal with sharp corners with a high
accuracy than traditional methods.
Abstract: In this work a surgical simulator is produced which
enables a training otologist to conduct a virtual, real-time prosthetic
insertion. The simulator provides the Ear, Nose and Throat surgeon
with real-time visual and haptic responses during virtual cochlear
implantation into a 3D model of the human Scala Tympani (ST). The
parametric model is derived from measured data as published in the
literature and accounts for human morphological variance, such as
differences in cochlear shape, enabling patient-specific pre- operative
assessment. Haptic modeling techniques use real physical data and
insertion force measurements, to develop a force model which
mimics the physical behavior of an implant as it collides with the ST
walls during an insertion. Output force profiles are acquired from the
insertion studies conducted in the work, to validate the haptic model.
The simulator provides the user with real-time, quantitative insertion
force information and associated electrode position as user inserts the
virtual implant into the ST model. The information provided by this
study may also be of use to implant manufacturers for design
enhancements as well as for training specialists in optimal force
administration, using the simulator. The paper reports on the methods
for anatomical modeling and haptic algorithm development, with
focus on simulator design, development, optimization and validation.
The techniques may be transferrable to other medical applications
that involve prosthetic device insertions where user vision is
obstructed.