Abstract: A rare phenomenon of SDS-induced activation of a latent protease activity associated with the purified silkworm excretory red fluorescent protein (SE-RFP) was noticed. SE-RFP aliquots incubated with SDS for different time intervals indicated that the protein undergoes an obligatory breakdown into a number of subunits which exhibit autoproteolytic (acting upon themselves) and/or heteroproteolytic (acting on other proteins) activities. A strong serine protease activity of SE-RFP subunits on Bombyx mori nucleopolyhedrovirus (BmNPV) polyhedral protein was detected by zymography technique. A complete inhibition of BmNPV infection to silkworms was observed by the oral administration assay of the SE-RFP. Here, it is proposed that the SE-RFP prevents the initial infection of BmNPV to silkworms by obliterating the polyhedral protein. This is the first report on a silkworm red fluorescent protein that exhibits a protease activity on exposure to SDS. The present studies would help in understanding the antiviral mechanism of silkworm red fluorescent proteins.
Abstract: Automatic reusability appraisal could be helpful in
evaluating the quality of developed or developing reusable software
components and in identification of reusable components from
existing legacy systems; that can save cost of developing the software
from scratch. But the issue of how to identify reusable components
from existing systems has remained relatively unexplored. In this
paper, we have mentioned two-tier approach by studying the
structural attributes as well as usability or relevancy of the
component to a particular domain. Latent semantic analysis is used
for the feature vector representation of various software domains. It
exploits the fact that FeatureVector codes can be seen as documents
containing terms -the idenifiers present in the components- and so
text modeling methods that capture co-occurrence information in
low-dimensional spaces can be used. Further, we devised Neuro-
Fuzzy hybrid Inference System, which takes structural metric values
as input and calculates the reusability of the software component.
Decision tree algorithm is used to decide initial set of fuzzy rules for
the Neuro-fuzzy system. The results obtained are convincing enough
to propose the system for economical identification and retrieval of
reusable software components.
Abstract: This paper develops an unscented grid-based filter
and a smoother for accurate nonlinear modeling and analysis
of time series. The filter uses unscented deterministic sampling
during both the time and measurement updating phases, to approximate
directly the distributions of the latent state variable. A
complementary grid smoother is also made to enable computing
of the likelihood. This helps us to formulate an expectation
maximisation algorithm for maximum likelihood estimation of
the state noise and the observation noise. Empirical investigations
show that the proposed unscented grid filter/smoother compares
favourably to other similar filters on nonlinear estimation tasks.
Abstract: The aim of this study was to estimate the frequency of
EBV infection in Hodgkin's lymphoma (HL) and non-Hodgkin's
lymphoma (NHL) occurring in Jordanian patients. A total of 55
patients with lymphoma were examined in this study. Of 55 patients,
30 and 25 were diagnosed as HL and NHL, respectively. The four
HL subtypes were observed with the majority of the cases exhibited
the mixed cellularity (MC) subtype followed by the nodular sclerosis
(NS). The high grade was found to be the commonest subtype of
NHL in our sample, followed by the low grade. The presence of EBV
virus was detected by immunostating for expression of latent
membrane protein-1 (LMP-1). The frequency of LMP-1 expression
occurred more frequent in patients with HL (60.0%) than in patients
with NHL (32.0%). The frequency of LMP-1 expression was also
higher in patients with MC subtype (61.11%) than those patients with
NS (28.57%). No age or gender difference in occurrence of EBV
infection was observed among patient with HL. By contrast, the
prevalence of EBV infection in NHL patients aged below 50 was
lower (16.66%) than in NHL patients aged 50 or above (46.15%). In
addition, EBV infection was more frequent in females with NHL
(38.46%) than in male with NHL (25%). In NHL cases, the
frequency of EBV infection in intermediate grade (60.0%) was high
when compared with frequency of low (25%) or high grades (25%).
In conclusion, analysis of LMP-1 expression indicates an important
role for this viral oncogene in the pathogenesis of EBV-associated
malignant lymphomas. These data also support the previous findings
that people with EBV may develop lymphoma and that efforts to
maintain low lymphoma should be considered for people with EBV
infection.
Abstract: In this research, a latent class vector model for pairwise data is formulated. As compared to the basic vector model, this model yields consistent estimates of the parameters since the number of parameters to be estimated does not increase with the number of subjects. The result of the analysis reveals that the model was stable and could classify each subject to the latent classes representing the typical scales used by these subjects.
Abstract: The present paper was concerned primarily with the
analysis, simulation of the air flow and thermal patterns in a lecture
room. The paper is devoted to numerically investigate the influence
of location and number of ventilation and air conditioning supply and
extracts openings on air flow properties in a lecture room. The work
focuses on air flow patterns, thermal behaviour in lecture room where
large number of students. The effectiveness of an air flow system is
commonly assessed by the successful removal of sensible and latent
loads from occupants with additional of attaining air pollutant at a
prescribed level to attain the human thermal comfort conditions and
to improve the indoor air quality; this is the main target during the
present paper. The study is carried out using computational fluid
dynamics (CFD) simulation techniques as embedded in the
commercially available CFD code (FLUENT 6.2). The CFD
modelling techniques solved the continuity, momentum and energy
conservation equations in addition to standard k – ε model equations
for turbulence closure.
Throughout the investigations, numerical validation is carried out by
way of comparisons of numerical and experimental results. Good
agreement is found among both predictions.
Abstract: Nevertheless the widespread application of finite
mixture models in segmentation, finite mixture model selection is
still an important issue. In fact, the selection of an adequate number
of segments is a key issue in deriving latent segments structures and
it is desirable that the selection criteria used for this end are effective.
In order to select among several information criteria, which may
support the selection of the correct number of segments we conduct a
simulation study. In particular, this study is intended to determine
which information criteria are more appropriate for mixture model
selection when considering data sets with only categorical
segmentation base variables. The generation of mixtures of
multinomial data supports the proposed analysis. As a result, we
establish a relationship between the level of measurement of
segmentation variables and some (eleven) information criteria-s
performance. The criterion AIC3 shows better performance (it
indicates the correct number of the simulated segments- structure
more often) when referring to mixtures of multinomial segmentation
base variables.
Abstract: The malfunction of thermal protection system (TPS) caused by aerodynamic heating is a latent trouble to aircraft structure safety. Accurately predicting the structure temperature field is quite important for the TPS design of hypersonic vehicle. Since Thornton’s work in 1988, the coupled method of aerodynamic heating and heat transfer has developed rapidly. However, little attention has been paid to the influence of structural deformation on aerodynamic heating and structural temperature field. In the flight, especially the long-endurance flight, the structural deformation, caused by the aerodynamic heating and temperature rise, has a direct impact on the aerodynamic heating and structural temperature field. Thus, the coupled interaction cannot be neglected. In this paper, based on the method of static aero-thermo-elasticity, considering the influence of aero-thermo-elasticity deformation, the aerodynamic heating and heat transfer coupled results of hypersonic vehicle wing model were calculated. The results show that, for the low-curvature region, such as fuselage or center-section wing, structure deformation has little effect on temperature field. However, for the stagnation region with high curvature, the coupled effect is not negligible. Thus, it is quite important for the structure temperature prediction to take into account the effect of elastic deformation. This work has laid a solid foundation for improving the prediction accuracy of the temperature distribution of aircraft structures and the evaluation capacity of structural performance.
Abstract: The aim of this research was to calculate the thermal
properties of Au3Ni Nanowire. The molecular dynamics (MD)
simulation technique was used to obtain the effect of radius size on
the energy, the melting temperature and the latent heat of fusion at
the isobaric-isothermal (NPT) ensemble. The Quantum Sutton-Chen
(Q-SC) many body interatomic potentials energy have been used for
Gold (Au) and Nickel (Ni) elements and a mixing rule has been
devised to obtain the parameters of these potentials for nanowire
stats. Our MD simulation results show the melting temperature and
latent heat of fusion increase upon increasing diameter of nanowire.
Moreover, the cohesive energy decreased with increasing diameter of
nanowire.
Abstract: PCMs have always been viewed as a suitable
candidate for off peak thermal storage, particularly for refrigeration
systems, due to the high latent energy densities of these materials.
However, due to the need to have them encapsulated within a
container this density is reduced. Furthermore, PCMs have a low
thermal conductivity which reduces the useful amount of energy
which can be stored. To consider these factors, the true energy
storage density of a PCM system was proposed and optimised for
PCMs encapsulated in slabs. Using a validated numerical model of
the system, a parametric study was undertaken to investigate the
impact of the slab thickness, gap between slabs and the mass flow
rate. The study showed that, when optimised, a PCM system can
deliver a true energy storage density between 53% and 83% of the
latent energy density of the PCM.
Abstract: The purpose of this study was to develop a “teachers’
self-efficacy scale for high school physical education teachers
(TSES-HSPET)” in Taiwan. This scale is based on the self-efficacy
theory of Bandura [1], [2]. This study used exploratory and
confirmatory factor analyses to test the reliability and validity. The
participants were high school physical education teachers in Taiwan.
Both stratified random sampling and cluster sampling were used to
sample participants for the study. 350 teachers were sampled in the
first stage and 234 valid scales (male 133, female 101) returned.
During the second stage, 350 teachers were sampled and 257 valid
scales (male 143, female 110, 4 did not indicate gender) returned. The
exploratory factor analysis was used in the first stage, and it got
60.77% of total variance for construct validity. The Cronbach’s alpha
coefficient of internal consistency was 0.91 for sumscale, and
subscales were 0.84 and 0.90. In the second stage, confirmatory factor
analysis was used to test construct validity. The result showed that the
fit index could be accepted (χ2 (75) =167.94, p
Abstract: The study and development of an innovative material
for building insulation is really important for a sustainable society in order to improve comfort and reducing energy consumption. The aim of this work is the development of insulating panels for
sustainable buildings based on an innovative material made by
cardboard and Phase Change Materials (PCMs).
The research has consisted in laboratory tests whose purpose has been the obtaining of the required properties for insulation panels: lightweight, porous structures and mechanical resistance. PCMs have been used for many years in the building industry as
smart insulation technology because of their properties of storage and release high quantity of latent heat at useful specific temperatures [1]- [2].
The integration of PCMs into cellulose matrix during the waste paper recycling process has been developed in order to obtain a
composite material.
Experiments on the productive process for the realization of insulating panels were done in order to make the new material
suitable for building application. The addition of rising agents
demonstrated the possibility to obtain a lighter structure with better
insulation properties.
Several tests were conducted to verify the new panel properties. The results obtained have shown the possibility to realize an
innovative and sustainable material suitable to replace insulating panels currently used.
Abstract: In the present work an investigation of the effects of
the air frontal velocity, relative humidity and dry air temperature on
the heat transfer characteristics of plain finned tube evaporator has
been conducted. Using an appropriate correlation for the air side heat
transfer coefficient the temperature distribution along the fin surface
was calculated using a dimensionless temperature distribution. For a
constant relative humidity and bulb temperature, it is found that the
temperature distribution decreases with increasing air frontal
velocity. Apparently, it is attributed to the condensate water film
flowing over the fin surface. When dry air temperature and face
velocity are being kept constant, the temperature distribution
decreases with the increase of inlet relative humidity. An increase in
the inlet relative humidity is accompanied by a higher amount of
moisture on the fin surface. This results in a higher amount of latent
heat transfer which involves higher fin surface temperature. For the
influence of dry air temperature, the results here show an increase in
the dimensionless temperature parameter with a decrease in bulb
temperature. Increasing bulb temperature leads to higher amount of
sensible and latent heat transfer when other conditions remain
constant.
Abstract: In this research work, investigations are carried out on
Continuous Wave (CW) Nd:YAG laser welding system after
preliminary experimentation to understand the influencing parameters
associated with laser welding of AISI 304. The experimental
procedure involves a series of laser welding trials on AISI 304
stainless steel sheets with various combinations of process parameters
like beam power, beam incident angle and beam incident angle. An
industrial 2 kW CW Nd:YAG laser system, available at Welding
Research Institute (WRI), BHEL Tiruchirappalli, is used for
conducting the welding trials for this research. After proper tuning of
laser beam, laser welding experiments are conducted on AISI 304
grade sheets to evaluate the influence of various input parameters on
weld bead geometry i.e. bead width (BW) and depth of penetration
(DOP). From the laser welding results, it is noticed that the beam
power and welding speed are the two influencing parameters on
depth and width of the bead. Three dimensional finite element
simulation of high density heat source have been performed for laser
welding technique using finite element code ANSYS for predicting
the temperature profile of laser beam heat source on AISI 304
stainless steel sheets. The temperature dependent material properties
for AISI 304 stainless steel are taken into account in the simulation,
which has a great influence in computing the temperature profiles.
The latent heat of fusion is considered by the thermal enthalpy of
material for calculation of phase transition problem. A Gaussian
distribution of heat flux using a moving heat source with a conical
shape is used for analyzing the temperature profiles. Experimental
and simulated values for weld bead profiles are analyzed for stainless
steel material for different beam power, welding speed and beam
incident angle. The results obtained from the simulation are
compared with those from the experimental data and it is observed
that the results of numerical analysis (FEM) are in good agreement
with experimental results, with an overall percentage of error
estimated to be within ±6%.
Abstract: Bidding is a very important business function to find
latent contractors of construction projects. Moreover, bid markup is
one of the most important decisions for a bidder to gain a reasonable
profit. Since the bidding system is a complex adaptive system, bidding
agent need a learning process to get more valuable knowledge for a bid,
especially from past public bidding information. In this paper, we
proposed an iterative agent leaning model for bidders to make markup
decisions. A classifier for public bidding information named PIBS is
developed to make full use of history data for classifying new bidding
information. The simulation and experimental study is performed to
show the validity of the proposed classifier. Some factors that affect
the validity of PIBS are also analyzed at the end of this work.
Abstract: This paper discusses the classification process for medical data. In this paper, we use the data from ACM KDDCup 2008 to demonstrate our classification process based on latent topic discovery. In this data set, the target set and outliers are quite different in their nature: target set is only 0.6% size in total, while the outliers consist of 99.4% of the data set. We use this data set as an example to show how we dealt with this extremely biased data set with latent topic discovery and noise reduction techniques. Our experiment faces two major challenge: (1) extremely distributed outliers, and (2) positive samples are far smaller than negative ones. We try to propose a suitable process flow to deal with these issues and get a best AUC result of 0.98.
Abstract: Web usage mining algorithms have been widely
utilized for modeling user web navigation behavior. In this study we
advance a model for mining of user-s navigation pattern. The model
makes user model based on expectation-maximization (EM)
algorithm.An EM algorithm is used in statistics for finding maximum
likelihood estimates of parameters in probabilistic models, where the
model depends on unobserved latent variables. The experimental
results represent that by decreasing the number of clusters, the log
likelihood converges toward lower values and probability of the
largest cluster will be decreased while the number of the clusters
increases in each treatment.
Abstract: Unified Theory of Acceptance and Use of Technology
(UTAUT) model has demonstrated the influencing factors for generic
information systems use such as tablet personal computer (TPC) and
mobile communication. However, in the context of digital library
system, there has been very little effort to determine factors affecting
the intention to use digital library based on the UTAUT model. This
paper investigates factors that are expected to influence the intention
of postgraduate students to use digital library based on modified
UTAUT model. The modified model comprises of constructs
represented by several latent variables, namely performance
expectancy (PE), effort expectancy (EE), information quality (IQ)
and service quality (SQ) and moderated by age, gender and
experience in using digital library. Results show that performance
expectancy, effort expectancy and information quality are positively
related to the intention to use digital library, while service quality is
negatively related to the intention to use digital library. Age and
gender have shown no evidence of any significant interactions, while
experience in using digital library significantly interacts with effort
expectancy and intention to use digital library. This has provided the
evidence of a moderating effect of experience in the intention to use
digital library. It is expected that this research will shed new lights
into research of acceptance and intention to use the library in a digital
environment.
Abstract: Deprivation indices are widely used in public health
study. These indices are also referred as the index of inequalities or
disadvantage. Even though, there are many indices that have been
built before, it is believed to be less appropriate to use the existing
indices to be applied in other countries or areas which had different
socio-economic conditions and different geographical characteristics.
The objective of this study is to construct the index based on the
geographical and socio-economic factors in Peninsular Malaysia
which is defined as the weighted household-based deprivation index.
This study has employed the variables based on household items,
household facilities, school attendance and education level obtained
from Malaysia 2000 census report. The factor analysis is used to
extract the latent variables from indicators, or reducing the
observable variable into smaller amount of components or factor.
Based on the factor analysis, two extracted factors were selected,
known as Basic Household Amenities and Middle-Class Household
Item factor. It is observed that the district with a lower index values
are located in the less developed states like Kelantan, Terengganu
and Kedah. Meanwhile, the areas with high index values are located
in developed states such as Pulau Pinang, W.P. Kuala Lumpur and
Selangor.
Abstract: The excessive consumption of fossil energies (electrical energy) during summer caused by the technological development involves more and more climate warming.
In order to reduce the worst impact of gas emissions produced from classical air conditioning, heat driven solar absorption chiller is pretty promising; it consists on using solar as motive energy which is clean and environmentally friendly to provide cold.
Solar absorption machine is composed by four components using Lithium Bromide /water as a refrigerating couple. LiBr- water is the most promising in chiller applications due to high safety, high volatility ratio, high affinity, high stability and its high latent heat. The lithium bromide solution is constitute by the salt lithium bromide which absorbs water under certain conditions of pressure and temperature however if the concentration of the solution is high in the absorption chillers; which exceed 70%, the solution will crystallize.
The main aim of this article is to study the phenomena of the crystallization and to evaluate how the dependence between the electric conductivity and the concentration which should be controlled.