Abstract: Characterization and evaluation of the activity of Vespa basalis DPP-IV, which expressed in Spodoptera frugiperda 21 cells. The expression of rDPP-IV was confirmed by SDS–PAGE, Western blot analyses, LC-MS/MS and measurement of its peptidase specificity. One-step purification by Ni-NTA affinity chromatography and the total amount of rDPP-IV recovered was approximately 6.4mg per liter from infected culture medium; an equivalent amount would be produced by 1x109 infected Sf21 insect cells. Through the affinity purification led to highly stable rDPP-IV enzyme was recovered and with significant peptidase activity. The rDPP-IV exhibited classical Michaelis–Menten kinetics, with kcat/Km in the range of 10-500 mM-1×S-1 for the five synthetic substrates and optimum substrate is Ala-Pro-pNA. As expected in inhibition assay, the enzymatic activity of rDPP-IV was significantly reduced by 80 or 60% in the presence of sitagliptin (a DPP-IV inhibitor) or PMSF (a serine protease inhibitor), but was not apparently affected by iodoacetamide (a cysteine protease inhibitor).
Abstract: This paper aims to develop a model that assists the
international retailer in selecting the country that maximizes the
degree of fit between the retailer-s goals and the country
characteristics in his initial internationalization move. A two-stage
multi criteria decision model is designed integrating the Analytic
Hierarchy Process (AHP) and Goal Programming. Ethical, cultural,
geographic and economic proximity are identified as the relevant
constructs of the internationalization decision. The constructs are
further structured into sub-factors within analytic hierarchy. The
model helps the retailer to integrate, rank and weigh a number of
hard and soft factors and prioritize the countries accordingly. The
model has been implemented on a Turkish luxury goods retailer who
was planning to internationalize. Actual entry of the specific retailer
in the selected country is a support for the model. Implementation on
a single retailer limits the generalizability of the results; however, the
emphasis of the paper is on construct identification and model
development. The paper enriches the existing literature by proposing
a hybrid multi objective decision model which introduces new soft
dimensions i.e. perceived distance, ethical proximity, humane
orientation to the decision process and facilitates effective decision
making.
Abstract: We report the size dependence of 1D superconductivity in ultrathin (10-130 nm) nanowires produced by coating suspended carbon nanotubes with a superconducting NbN thin film. The resistance-temperature characteristic curves for samples with ≧25 nm wire width show the superconducting transition. On the other hand, for the samples with 10-nm width, the superconducting transition is not exhibited owing to the quantum size effect. The differential resistance vs. current density characteristic curves show some peak, indicating that Josephson junctions are formed in nanowires. The presence of the Josephson junctions is well explained by the measurement of the magnetic field dependence of the critical current. These understanding allow for the further expansion of the potential application of NbN, which is utilized for single photon detectors and so on.
Abstract: In the present paper, we propose numerical methods for solving the Stein equation AXC - X - D = 0 where the matrix A is large and sparse. Such problems appear in discrete-time control problems, filtering and image restoration. We consider the case where the matrix D is of full rank and the case where D is factored as a product of two matrices. The proposed methods are Krylov subspace methods based on the block Arnoldi algorithm. We give theoretical results and we report some numerical experiments.
Abstract: In recent past, the Unified Modeling Language (UML) has become the de facto industry standard for object-oriented modeling of the software systems. The syntax and semantics rich UML has encouraged industry to develop several supporting tools including those capable of generating deployable product (code) from the UML models. As a consequence, ensuring the correctness of the model/design has become challenging and extremely important task. In this paper, we present an approach for automatic verification of protocol model/design. As a case study, Session Initiation Protocol (SIP) design is verified for the property, “the CALLER will not converse with the CALLEE before the connection is established between them ". The SIP is modeled using UML statechart diagrams and the desired properties are expressed in temporal logic. Our prototype verifier “UML-SMV" is used to carry out the verification. We subjected an erroneous SIP model to the UML-SMV, the verifier could successfully detect the error (in 76.26ms) and generate the error trace.
Abstract: One of the main research methods in humanistic studies is the collection and process of data through questionnaires. This paper reports our experiences of localizing and adapting the phpESP package of electronic surveys, which led to a friendly on-line questionnaire environment offered through our department web site. After presenting the characteristics of this environment, we identify the expected benefits and present a questionnaire carried out through both the traditional and electronic way. We present the respondents' feedback and then we report the researchers' opinions.Finally, we propose ideas we intend to implement in order to further assist and enhance the research based on this web accessed,electronic questionnaire environment.
Abstract: Prior research has examined the relationship between religiosity, religious involvement, and involvement in secular, civic organizations. However, research has not examined the influence of religious involvement on secular, non-civic organizations (i.e. work organizations). This study examines the link between religiosity, religious involvement, and the three-component model of organizational commitment. More specifically, the author hypothesizes that individuals high in religiosity (and religious involvement) will have lower affective, continuance, and normative commitment than less religious (or non-religious) individuals. In addition, it is hypothesized that this relationship is moderated by a third factor: organizational spirituality. Further, the author hypothesizes that for organizations that are spiritual the negative relationship between religiosity and job commitment will be weakened or even negated.
Abstract: Restarted GMRES methods augmented with approximate eigenvectors are widely used for solving large sparse linear systems. Recently a new scheme of augmenting with error approximations is proposed. The main aim of this paper is to develop a restarted GMRES method augmented with the combination of harmonic Ritz vectors and error approximations. We demonstrate that the resulted combination method can gain the advantages of two approaches: (i) effectively deflate the small eigenvalues in magnitude that may hamper the convergence of the method and (ii) partially recover the global optimality lost due to restarting. The effectiveness and efficiency of the new method are demonstrated through various numerical examples.
Abstract: In this paper a fast motion estimation method for
H.264/AVC named Triplet Search Motion Estimation (TS-ME) is
proposed. Similar to some of the traditional fast motion estimation
methods and their improved proposals which restrict the search points
only to some selected candidates to decrease the computation
complexity, proposed algorithm separate the motion search process to
several steps but with some new features. First, proposed algorithm try
to search the real motion area using proposed triplet patterns instead of
some selected search points to avoid dropping into the local minimum.
Then, in the localized motion area a novel 3-step motion search
algorithm is performed. Proposed search patterns are categorized into
three rings on the basis of the distance from the search center. These
three rings are adaptively selected by referencing the surrounding
motion vectors to early terminate the motion search process. On the
other hand, computation reduction for sub pixel motion search is also
discussed considering the appearance probability of the sub pixel
motion vector. From the simulation results, motion estimation speed
improved by a factor of up to 38 when using proposed algorithm than
that of the reference software of H.264/AVC with ignorable picture
quality loss.
Abstract: Double-diffusive natural convection in an open top
square cavity and heated from the side is studied numerically.
Constant temperatures and concentration are imposed along the right
and left walls while the heat balance at the surface is assumed to obey
Newton-s law of cooling. The finite difference method is used to
solve the dimensionless governing equations. The numerical results
are reported for the effect of Marangoni number, Biot number and
Prandtl number on the contours of streamlines, temperature and
concentration. The predicted results for the average Nusselt number
and Sherwood number are presented for various parametric
conditions. The parameters involved are as follows; the thermal
Marangoni number, 0 ≤ MaT ≤1000 , the solutal Marangoni number,
0 1000 c ≤ Ma ≤ , the Biot number, 0 ≤ Bi ≤ 6 , Grashof number,
5 Gr = 10 and aspect ratio 1. The study focused on both flows; thermal
dominated, N = 0.8 , and compositional dominated, N = 1.3 .
Abstract: Prior research has not effectively investigated how the
profitability of Chinese branches affect FDIs in China [1, 2], so this
study for the first time incorporates realistic earnings information
to systematically investigate effects of innovation, imitation, and
profit factors of FDI diffusions from Taiwan to China. Our nonlinear
least square (NLS) model, which incorporates earnings factors,
forms a nonlinear ordinary differential equation (ODE) in numerical
simulation programs. The model parameters are obtained through
a genetic algorithms (GA) technique and then optimized with the
collected data for the best accuracy. Particularly, Taiwanese regulatory
FDI restrictions are also considered in our modified model to meet
the realistic conditions. To validate the model-s effectiveness, this
investigation compares the prediction accuracy of modified model
with the conventional diffusion model, which does not take account
of the profitability factors.
The results clearly demonstrate the internal influence to be positive,
as early FDI adopters- consistent praises of FDI attract potential firms
to make the same move. The former erects a behavior model for the
latter to imitate their foreign investment decision. Particularly, the
results of modified diffusion models show that the earnings from
Chinese branches are positively related to the internal influence. In
general, the imitating tendency of potential consumers is substantially
hindered by the losses in the Chinese branches, and these firms would
invest less into China. The FDI inflow extension depends on earnings
of Chinese branches, and companies will adjust their FDI strategies
based on the returns. Since this research has proved that earning is
an influential factor on FDI dynamics, our revised model explicitly
performs superior in prediction ability than conventional diffusion
model.
Abstract: The aerodynamics characteristics of a blended-wing body (BWB) aircraft were obtained in Universiti Teknologi MARA low speed wind tunnel. The scaled-down of BWB model consisted of a canard as its horizontal stabilizer. There were four canards with different aspect ratio used in the experiments. Canard setting angles were varied from -20q to 20q. All tests were conducted at velocity of 35 m/s, with Mach number 0.1. At low angles of attacks, the increment of lift slope for various canards aspect ratio is small and almost constant. Higher canard aspect ratio will cause higher drag. However, canard has a high effect to the moment at zero lift, CM,0.The visualization using mini tuff was performed to observe the airflow at the upper surface of canard. KeywordsAerodynamics,blended-wing body, canard, wind tunnel.
Abstract: This analysis investigates the distortion of flow
measurement and the increase of cavitation along orifice
flowmeter. The analysis using the numerical method (CFD)
validated the distortion of flow measurement through the inlet
velocity profile considering the convergence and grid
dependency. Realizable k-e model was selected and y+ was
about 50 in this numerical analysis. This analysis also estimated
the vulnerability of cavitation effect due to inlet velocity profile.
The investigation concludes that inclined inlet velocity profile
could vary the pressure which was measured at pressure tab
near pipe wall and it led to distort the pressure values ranged
from -3.8% to 5.3% near the orifice plate and to make the
increase of cavitation. The investigation recommends that the
fully developed inlet velocity flow is beneficial to accurate flow
measurement in orifice flowmeter.
Abstract: Carbon nanotubes (CNTs) possess unique structural,
mechanical, thermal and electronic properties, and have been
proposed to be used for applications in many fields. However, to
reach the full potential of the CNTs, many problems still need to be
solved, including the development of an easy and effective
purification procedure, since synthesized CNTs contain impurities,
such as amorphous carbon, carbon nanoparticles and metal particles.
Different purification methods yield different CNT characteristics
and may be suitable for the production of different types of CNTs. In
this study, the effect of different purification chemicals on carbon
nanotube quality was investigated. CNTs were firstly synthesized by
chemical vapor deposition (CVD) of acetylene (C2H2) on a
magnesium oxide (MgO) powder impregnated with an iron nitrate
(Fe(NO3)3·9H2O) solution. The synthesis parameters were selected
as: the synthesis temperature of 800°C, the iron content in the
precursor of 5% and the synthesis time of 30 min. The liquid phase
oxidation method was applied for the purification of the synthesized
CNT materials. Three different acid chemicals (HNO3, H2SO4, and
HCl) were used in the removal of the metal catalysts from the
synthesized CNT material to investigate the possible effects of each
acid solution to the purification step. Purification experiments were
carried out at two different temperatures (75 and 120 °C), two
different acid concentrations (3 and 6 M) and for three different time
intervals (6, 8 and 15 h). A 30% H2O2 : 3M HCl (1:1 v%) solution
was also used in the purification step to remove both the metal
catalysts and the amorphous carbon. The purifications using this
solution were performed at the temperature of 75°C for 8 hours.
Purification efficiencies at different conditions were evaluated by
thermogravimetric analysis. Thermal and electrical properties of
CNTs were also determined. It was found that the obtained electrical
conductivity values for the carbon nanotubes were typical for organic
semiconductor materials and thermal stabilities were changed
depending on the purification chemicals.
Abstract: Understanding of how and where NOx formation
occurs in industrial burner is very important for efficient and clean
operation of utility burners. Also the importance of this problem is
mainly due to its relation to the pollutants produced by more burners
used widely of gas turbine in thermal power plants and glass and steel
industry.
In this article, a numerical model of an industrial burner operating
in MILD combustion is validated with experimental data.. Then
influence of air flow rate and air temperature on combustor
temperature profiles and NOX product are investigated. In order to
modification this study reports on the effects of fuel and air dilution
(with inert gases H2O, CO2, N2), and also influence of lean-premixed
of fuel, on the temperature profiles and NOX emission.
Conservation equations of mass, momentum and energy, and
transport equations of species concentrations, turbulence, combustion
and radiation modeling in addition to NO modeling equations were
solved together to present temperature and NO distribution inside the
burner.
The results shows that dilution, cause to a reduction in value of
temperature and NOX emission, and suppresses any flame
propagation inside the furnace and made the flame inside the furnace
invisible. Dilution with H2O rather than N2 and CO2 decreases further
the value of the NOX. Also with raise of lean-premix level, local
temperature of burner and the value of NOX product are decreases
because of premixing prevents local “hot spots" within the combustor
volume that can lead to significant NOx formation. Also leanpremixing
of fuel with air cause to amount of air in reaction zone is
reach more than amount that supplied as is actually needed to burn
the fuel and this act lead to limiting NOx formation
Abstract: Physiological control of a left ventricle assist device (LVAD) is generally a complicated task due to diverse operating environments and patient variability. In this work, a tracking control algorithm based on sliding mode and feed forward control for a class of discrete-time single input single output (SISO) nonlinear uncertain systems is presented. The controller was developed to track the reference trajectory to a set operating point without inducing suction in the ventricle. The controller regulates the estimated mean pulsatile flow Qp and mean pulsatility index of pump rotational speed PIω that was generated from a model of the assist device. We recall the principle of the sliding mode control theory then we combine the feed-forward control design with the sliding mode control technique to follow the reference trajectory. The uncertainty is replaced by its upper and lower boundary. The controller was tested in a computer simulation covering two scenarios (preload and ventricular contractility). The simulation results prove the effectiveness and the robustness of the proposed controller
Abstract: Double-diffusive steady convection in a partially
porous cavity with partially permeable walls and under the combined
buoyancy effects of thermal and mass diffusion was analysed
numerically using finite volume method.
The top wall is well insulated and impermeable while the bottom
surface is partially well insulated and impermeable and partially
submitted to constant temperature T1 and concentration C1. Constant
equal temperature T2 and concentration C2 are imposed along the
vertical surfaces of the enclosure. Mass suction/injection and
injection/suction are respectively considered at the bottom of the
porous centred partition and at one of the vertical walls.
Heat and mass transfer characteristics as streamlines and average
Nusselt numbers and Sherwood numbers were discussed for different
values of buoyancy ratio, Rayleigh number, and injection/suction
coefficient.
It is especially noted that increasing the injection factor
disadvantages the exchanges in the case of the injection while the
transfer is augmented in case of suction. On the other hand, a critical
value of the buoyancy ratio was highlighted for which heat and mass
transfers are minimized.
Abstract: A new numerical method for solving the twodimensional,
steady, incompressible, viscous flow equations on a
Curvilinear staggered grid is presented in this paper. The proposed
methodology is finite difference based, but essentially takes
advantage of the best features of two well-established numerical
formulations, the finite difference and finite volume methods. Some
weaknesses of the finite difference approach are removed by
exploiting the strengths of the finite volume method. In particular,
the issue of velocity-pressure coupling is dealt with in the proposed
finite difference formulation by developing a pressure correction
equation in a manner similar to the SIMPLE approach commonly
used in finite volume formulations. However, since this is purely a
finite difference formulation, numerical approximation of fluxes is
not required. Results obtained from the present method are based on
the first-order upwind scheme for the convective terms, but the
methodology can easily be modified to accommodate higher order
differencing schemes.
Abstract: The main objective of seismic rehabilitation in the
foundations is decreasing the range of horizontal and vertical
vibrations and omitting high frequencies contents under the seismic
loading. In this regard, the advantages of micropiles network is
utilized. Reduction in vibration range of foundation can be achieved
by using high dynamic rigidness module such as deep foundations. In
addition, natural frequency of pile and soil system increases in regard
to rising of system rigidness. Accordingly, the main strategy is
decreasing of horizontal and vertical seismic vibrations of the
structure. In this case, considering the impact of foundation, pile and
improved soil foundation is a primary concern. Therefore, in this
paper, effective factors are studied on the seismic rehabilitation of
foundations applying network micropiles in sandy soils with
nonlinear reaction.
Abstract: A model of a system concerning one species of demersal
(inshore) fish and one of pelagic (offshore) fish undergoing fishing
restricted by marine protected areas is proposed in this paper. This
setup was based on the FISH-BE model applied to the Tabina fishery
in Zamboanga del Sur, Philippines. The components of the model
equations have been adapted from widely-accepted mechanisms in
population dynamics. The model employs Gompertz-s law of growth
and interaction on each type of protected and unprotected subpopulation.
Exchange coefficients between protected and unprotected
areas were assumed to be proportional to the relative area of the
entry region. Fishing harvests were assumed to be proportional to
both the number of fishers and the number of unprotected fish. An
extra term was included for the pelagic population to allow for the
exchange between the unprotected area and the outside environment.
The systems were found to be bounded for all parameter values. The
equations for the steady state were unsolvable analytically but the
existence and uniqueness of non-zero steady states can be proven.
Plots also show that an MPA size yielding the maximum steady state
of the unprotected population can be found. All steady states were
found to be globally asymptotically stable for the entire range of
parameter values.