Mining Genes Relations in Microarray Data Combined with Ontology in Colon Cancer Automated Diagnosis System

MATCH project [1] entitle the development of an automatic diagnosis system that aims to support treatment of colon cancer diseases by discovering mutations that occurs to tumour suppressor genes (TSGs) and contributes to the development of cancerous tumours. The constitution of the system is based on a) colon cancer clinical data and b) biological information that will be derived by data mining techniques from genomic and proteomic sources The core mining module will consist of the popular, well tested hybrid feature extraction methods, and new combined algorithms, designed especially for the project. Elements of rough sets, evolutionary computing, cluster analysis, self-organization maps and association rules will be used to discover the annotations between genes, and their influence on tumours [2]-[11]. The methods used to process the data have to address their high complexity, potential inconsistency and problems of dealing with the missing values. They must integrate all the useful information necessary to solve the expert's question. For this purpose, the system has to learn from data, or be able to interactively specify by a domain specialist, the part of the knowledge structure it needs to answer a given query. The program should also take into account the importance/rank of the particular parts of data it analyses, and adjusts the used algorithms accordingly.

GODYS-PC: a Software Package for Modeling,Simulating and Analyzing Dynamic Systems

In this paper, we introduce GODYS-PC software package for modeling, simulating and analyzing dynamic systems. To illustrate the use of GODYS-PC we present a few examples which concern modeling and simulating of engineering systems. In order to compare GODYS-PC with widely used in academia and industry Simulink®, the same examples are provided both in GODYS-PC and Simulink®.

Convection through Light Weight Timber Constructions with Mineral Wool

The major part of light weight timber constructions consists of insulation. Mineral wool is the most commonly used insulation due to its cost efficiency and easy handling. The fiber orientation and porosity of this insulation material enables flowthrough. The air flow resistance is low. If leakage occurs in the insulated bay section, the convective flow may cause energy losses and infiltration of the exterior wall with moisture and particles. In particular the infiltrated moisture may lead to thermal bridges and growth of health endangering mould and mildew. In order to prevent this problem, different numerical calculation models have been developed. All models developed so far have a potential for completion. The implementation of the flow-through properties of mineral wool insulation may help to improve the existing models. Assuming that the real pressure difference between interior and exterior surface is larger than the prescribed pressure difference in the standard test procedure for mineral wool ISO 9053 / EN 29053, measurements were performed using the measurement setup for research on convective moisture transfer “MSRCMT". These measurements show, that structural inhomogeneities of mineral wool effect the permeability only at higher pressure differences, as applied in MSRCMT. Additional microscopic investigations show, that the location of a leak within the construction has a crucial influence on the air flow-through and the infiltration rate. The results clearly indicate that the empirical values for the acoustic resistance of mineral wool should not be used for the calculation of convective transfer mechanisms.

Graphical Password Security Evaluation by Fuzzy AHP

In today's day and age, one of the important topics in information security is authentication. There are several alternatives to text-based authentication of which includes Graphical Password (GP) or Graphical User Authentication (GUA). These methods stems from the fact that humans recognized and remembers images better than alphanumerical text characters. This paper will focus on the security aspect of GP algorithms and what most researchers have been working on trying to define these security features and attributes. The goal of this study is to develop a fuzzy decision model that allows automatic selection of available GP algorithms by taking into considerations the subjective judgments of the decision makers who are more than 50 postgraduate students of computer science. The approach that is being proposed is based on the Fuzzy Analytic Hierarchy Process (FAHP) which determines the criteria weight as a linear formula.

Palmprint based Cancelable Biometric Authentication System

A cancelable palmprint authentication system proposed in this paper is specifically designed to overcome the limitations of the contemporary biometric authentication system. In this proposed system, Geometric and pseudo Zernike moments are employed as feature extractors to transform palmprint image into a lower dimensional compact feature representation. Before moment computation, wavelet transform is adopted to decompose palmprint image into lower resolution and dimensional frequency subbands. This reduces the computational load of moment calculation drastically. The generated wavelet-moment based feature representation is used to generate cancelable verification key with a set of random data. This private binary key can be canceled and replaced. Besides that, this key also possesses high data capture offset tolerance, with highly correlated bit strings for intra-class population. This property allows a clear separation of the genuine and imposter populations, as well as zero Equal Error Rate achievement, which is hardly gained in the conventional biometric based authentication system.

Database Development and Discrimination Algorithms for Membrane Protein Functions

We have developed a database for membrane protein functions, which has more than 3000 experimental data on functionally important amino acid residues in membrane proteins along with sequence, structure and literature information. Further, we have proposed different methods for identifying membrane proteins based on their functions: (i) discrimination of membrane transport proteins from other globular and membrane proteins and classifying them into channels/pores, electrochemical and active transporters, and (ii) β-signal for the insertion of mitochondrial β-barrel outer membrane proteins and potential targets. Our method showed an accuracy of 82% in discriminating transport proteins and 68% to classify them into three different transporters. In addition, we have identified a motif for targeting β-signal and potential candidates for mitochondrial β-barrel membrane proteins. Our methods can be used as effective tools for genome-wide annotations.

Account Management Method with Blind Signature Scheme

Reducing the risk of information leaks is one of the most important functions of identity management systems. To achieve this purpose, Dey et al. have already proposed an account management method for a federated login system using a blind signature scheme. In order to ensure account anonymity for the authentication provider, referred to as an IDP (identity provider), a blind signature scheme is utilized to generate an authentication token on an authentication service and the token is sent to an IDP. However, there is a problem with the proposed system. Malicious users can establish multiple accounts on an IDP by requesting such accounts. As a measure to solve this problem, in this paper, the authors propose an account checking method that is performed before account generation.

2D Image Processing for DSO Astrophotography

The new concept of two–dimensional (2D) image processing implementation for auto-guiding system is shown in this paper. It is dedicated to astrophotography and operates with astronomy CCD guide cameras or with self-guided dual-detector CCD cameras and ST4 compatible equatorial mounts. This idea was verified by MATLAB model, which was used to test all procedures and data conversions. Next the circuit prototype was implemented at Altera MAX II CPLD device and tested for real astronomical object images. The digital processing speed of CPLD prototype board was sufficient for correct equatorial mount guiding in real-time system.

The Tyrosinase and Cyclooxygenase Inhibitory Activities and Cytotoxicity Screening of Tamarindus indica Seeds

The methanolic extracts from seeds of tamarind (Tamarindus indica) was prepared by Soxhlet apparatus extraction and evaluated for total phenolic content by Folin-Ciocalteu method. Then, methanolic extract was screened biological activities (In vitro) for anti-melanogenic activity by tyrosinase inhibition test, antiinflammation activity by cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) inhibition test, and cytotoxic screening test with Vero cells. The results showed that total phenolic content, which contained in extract, was contained 27.72 mg of gallic acid equivalent per g of dry weight. The ability to inhibit tyrosinase enzyme, which exerted by Tamarind seed extracts (1 mg/ml) was 52.13 ± 0.42 %. The extract was not possessed inhibitory effect to COX-1 and COX-2 enzymes and cytotoxic effect to Vero cells. The finding is concludes that tested seed extract was possessed antimelanogenic activity with non-toxic effects. However, there was not exhibited anti-inflammatory activity. Further studies include the use of advance biological models to confirm this biological activity, as well as, the isolation and characterization of the purified compounds that it was contained.

Characterization of Chemically Modified Biomass as a Coating Material for Controlled Released Urea by Contact Angle Measurement

Controlled release urea has become popular in agricultural industry as it helps to solve environmental issues and increase crop yield. Recently biomass was identified to replace the polymer used as a coating material in the conventional coated urea. In this paper spreading and contact angle of biomass droplet (lignin, cellulose and clay) on urea surface are investigated experimentally. There were two tests were conducted, sessile drop for contact angle measurement and pendant drop for contact angle measurement. A different concentration of biomass droplet was released from 30 mm above a substrate. Glass was used as a controlled substrate. Images were recorded as soon as the droplet impacted onto the urea before completely adsorb into the urea. Digitized droplets were then used to identify the droplet-s surface tension and contact angle. There is large difference observed between the low surface tension and high surface tension liquids, where the wetting and spreading diameter is higher for lower surface tension. From the contact angle results, the data showed that the biomass coating films were possible as wetting liquid (θ < 90º). Contact angle of biomass coating material gives good indication for the wettablity of a liquid on urea surface.

A Novel Method for Behavior Modeling in Uncertain Information Systems

None of the processing models in the software development has explained the software systems performance evaluation and modeling; likewise, there exist uncertainty in the information systems because of the natural essence of requirements, and this may cause other challenges in the processing of software development. By definition an extended version of UML (Fuzzy- UML), the functional requirements of the software defined uncertainly would be supported. In this study, the behavioral description of uncertain information systems by the aid of fuzzy-state diagram is crucial; moreover, the introduction of behavioral diagrams role in F-UML is investigated in software performance modeling process. To get the aim, a fuzzy sub-profile is used.

Weighted Harmonic Arnoldi Method for Large Interior Eigenproblems

The harmonic Arnoldi method can be used to find interior eigenpairs of large matrices. However, it has been shown that this method may converge erratically and even may fail to do so. In this paper, we present a new method for computing interior eigenpairs of large nonsymmetric matrices, which is called weighted harmonic Arnoldi method. The implementation of the method has been tested by numerical examples, the results show that the method converges fast and works with high accuracy.

The Influence of using Compost Leachate on Soil Reaction

In the area where the high quality water is not available, unconventional water sources are used to irrigate. Household leachate is one of the sources which are used in dry and semi dry areas in order to water the barer trees and plants. It meets the plants needs and also has some effects on the soil, but at the same time it might cause some problems as well. This study in order to evaluate the effect of using Compost leachate on the density of soil iron in form of a statistical pattern called ''Split Plot'' by using two main treatments, one subsidiary treatment and three repetitions of the pattern in a three month period. The main N treatments include: irrigation using well water as a blank treatments and the main I treatments include: irrigation using leachate and well water concurrently. Some subsidiary treatments were DI (Drop Irrigation) and SDI (Sub Drop Irrigation). Then in the established plots, 36 biannual pine and cypress shrubs were randomly grown. Two months later the treatment begins. The results revealed that there was a significant variation between the main treatment and the instance regarding pH decline in the soil which was related to the amount of leachate injected into the soil. After some time and using leachate the pH level fell, as much as 0.46 and also increased due to the great amounts of leachate. The underneath drop irrigation ends in better results than sub drop irrigation since it keeps the soil texture fixed.

Parametric Transition as a Spiral Curve and Its Application in Spur Gear Tooth with FEA

The exploration of this paper will focus on the Cshaped transition curve. This curve is designed by using the concept of circle to circle where one circle lies inside other. The degree of smoothness employed is curvature continuity. The function used in designing the C-curve is Bézier-like cubic function. This function has a low degree, flexible for the interactive design of curves and surfaces and has a shape parameter. The shape parameter is used to control the C-shape curve. Once the C-shaped curve design is completed, this curve will be applied to design spur gear tooth. After the tooth design procedure is finished, the design will be analyzed by using Finite Element Analysis (FEA). This analysis is used to find out the applicability of the tooth design and the gear material that chosen. In this research, Cast Iron 4.5 % Carbon, ASTM A-48 is selected as a gear material.

From Forbidden States to Linear Constraints

This paper deals with the problem of constructing constraints in non safe Petri Nets and then reducing the number of the constructed constraints. In a system, assigning some linear constraints to forbidden states is possible. Enforcing these constraints on the system prevents it from entering these states. But there is no a systematic method for assigning constraints to forbidden states in non safe Petri Nets. In this paper a useful method is proposed for constructing constraints in non safe Petri Nets. But when the number of these constraints is large enforcing them on the system may complicate the Petri Net model. So, another method is proposed for reducing the number of constructed constraints.

Rapid Urbanization and the Challenge of SustainableUrban Development in Palestinian Cities

Palestinian cities face the challenges of land scarcity, high population growth rates, rapid urbanization, uneven development and territorial fragmentation. Due to geopolitical constrains and the absence of an effective Palestinian planning institution, urban development in Palestinian cities has not followed any discernable planning scheme. This has led to a number of internal contradictions in the structure of cities, and adversely affected land use, the provision of urban services, and the quality of the living environment. This paper explores these challenges, and the potential that exists for introducing a more sustainable urban development pattern in Palestinian cities. It assesses alternative development approaches with a particular focus on sustainable development, promoting ecodevelopment imperatives, limiting random urbanization, and meeting present and future challenges, including fulfilling the needs of the people and conserving the scarce land and limited natural resources. This paper concludes by offering conceptual proposals and guidelines for promoting sustainable physical development in Palestinian cities.

En-Face Optical Coherence Tomography and Fluorescence in Evaluation of Orthodontic Interfaces

Bonding has become a routine procedure in several dental specialties – from prosthodontics to conservative dentistry and even orthodontics. In many of these fields it is important to be able to investigate the bonded interfaces to assess their quality. All currently employed investigative methods are invasive, meaning that samples are destroyed in the testing procedure and cannot be used again. We have investigated the interface between human enamel and bonded ceramic brackets non-invasively, introducing a combination of new investigative methods – optical coherence tomography (OCT), fluorescence OCT and confocal microscopy (CM). Brackets were conventionally bonded on conditioned buccal surfaces of teeth. The bonding was assessed using these methods. Three dimensional reconstructions of the detected material defects were developed using manual and semi-automatic segmentation. The results clearly prove that OCT, fluorescence OCT and CM are useful in orthodontic bonding investigations.

Application of Biogas Technology in Turkey

The potential, opportunities and drawbacks of biogas technology use in Turkey are evaluated in this paper. Turkey is dependent on foreign sources of energy. Therefore, use of biogas technology would provide a safe way of waste disposal and recovery of renewable energy, particularly from a sustainable domestic source, which is less unlikely to be influenced by international price or political fluctuations. Use of biogas technology would especially meet the cooking, heating and electricity demand in rural areas and protect the environment, additionally creating new job opportunities and improving social-economical conditions.

Performance of Ground Clay Bricks as Partial Cement Replacement in Grade 30 Concrete

Demolitions of buildings have created a lot of waste and one of it is clay bricks. The waste clay bricks were ground to roughly cement fineness and used to partially replaced cement at 10%, 20% and 30% with w/b ratio of 0.6 and tested at 7, 28, 60, 90 and 120 days. The result shows that the compressive strength of GCB concrete increases over age however, decreases as the level of replacements increases. It was also found that 10% replacement of GCB gave the highest compressive strength, however for optimum replacement, 30% was chosen as it still attained strength of grade 30 concrete. In terms of durability performances, results show that GCB replacement up to 30% was found to be efficient in reducing water absorption as well as water permeability. These studies show that GCB has the potential to be used as partial cement replacement in making concrete.

Photogrammetric Survey on the Natural Gas Pipeline Projects of Iran-Turkey- Europe (ITE)

The ITE Project is a project that has 1800 km length and across the Turkey's land through east to west. The project of pipeline enters geographically from Iran to Doğubayazit (Turkey) in the east, exits to Greece from Ipsala province of Turkey in the west. This project is the one of the international projects in such scale that provides the natural gas of Iran and Caspian Sea through the European continent. In this investigation, some information will be given about the methods used to verify the direction of the pipeline and the technical properties of the results obtained. The cost of project itself entirely depends on the direction of the pipeline which would be as short as possible and the specifications of the land cover. Production standards of 1/2000 scaled digital orthophoto and vectoral maps as a results of the use of map production materials and methods (such as high resolution satellite images, and digital aerial images captured from digital aerial cameras), will also be given in this report. According to Turkish national map production standards, TM ((Transversal Mercator, 3 degree) projection is used for large scale map and UTM (Universal Transversal Mercator, 6 degree) is used for small scale map production standards. Some information is also given about the projection used in the ITE natural gas pipeline project.