Spiral Cuff for Fiber-Diameter Selective VNS

In this paper we present the modeling, design, and experimental testing of a nerve cuff multi-electrode system for diameter-selective vagus nerve stimulation. The multi-electrode system contained ninety-nine platinum electrodes embedded within a self-curling spiral silicone sheet. The electrodes were organized in a matrix having nine parallel groups, each containing eleven electrodes. Preliminary testing of the nerve cuff was performed in an isolated segment of a swinish left cervical vagus nerve. For selective vagus nerve stimulation, precisely defined current quasitrapezoidal, asymmetric and biphasic stimulating pulses were applied to preselected locations along the left vagus segment via appointed group of three electrodes within the cuff. Selective stimulation was obtained by anodal block. However, these pulses may not be safe for a long-term application because of a frequently used high imbalance between the cathodic and anodic part of the stimulating pulse. Preliminary results show that the cuff was capable of exciting A and B-fibres, and, that for a certain range of parameters used in stimulating pulses, the contribution of A-fibres to the CAP was slightly reduced and the contribution of B-fibres was slightly larger. Results also showed that measured CAPs are not greatly influenced by the imbalance between a charge Qc injected in cathodic and Qa in anodic phase of quasitrapezoidal, asymmetric and biphasic pulses.

The Effect of Selective Cyclooxygenase (COX) Inhibitors on Japanese Medaka (Oryzias latipes) Reproduction Parameters

Our results showed that treatment with both cyclooxygenase (COX1 or COX2) inhibitors impair reproduction parameters of the medaka. Resveratrol (COX1 inhibitor) caused an decrease in the number of spawning females at the first week of feeding fish with experimental diets. In the group treated with NS- 398 (COX2 inhibitor) we found the lowest sperm velocity parameters and decreased linearity of movement. The ovaries of the medaka fed feed supplemented with Resveratrol or NS-398 were confirmed to have a lower share of matured oocytes however during the experiment (four weeks) the number of eggs spawned by females was similar. Both inhibitors in fish diet (20 mg/kg body weight/day) caused a decrease in the embryo survival. Our results revealed that for the medaka female reproduction, activity of both COX enzymes might be necessary whereas males reproduction competence, as expressed by sperm motility parameters, might be related to COX2 activity.

Implementation of a “DIVA“ Concept withspecific Elisa Kits; When Subunit H5 Avian Influenza Vaccine is used

The main objective of this study was to demonstrate that differentiation of infected and vaccinated animals (DIVA) strategy using different ELISA tests is possible when a subunit vaccine (Haemagglutinin protein) is used to prevent Avian influenza. Special emphasis was placed on the differentiation in the serological response to different components of the AIV (Nucleoprotein, Neuraminidase, Haemagglutinin, Nucleocapsid) between chickens that were vaccinated with a whole virus kill vaccine and recombinant vaccine. Furthermore, the potential use of this DIVA strategy using ELISA assays to detect Neuraminidase 1 (N1) was analyzed as strategy in countries where the field virus is H5N1 and the vaccine used is formulated with H5N2. Detection of AIV-s antibodies to any component in serum was negative for all animals on the study days 0-13. At study day 14 the titers of antibodies against Nucleoprotein (NP) and Nucleocapsid (NC) rose in the experimental groups vaccinated with Volvac® AI KV and were negatives during all the trial in the experimental groups vaccinated with a subunit H5; significant statistically differences were observed between these groups (p < 0.05). The seroconversion either Haemagglutinin or Neuraminidase was evident after 21 days post-vaccination in the experimental groups vaccinated with the respective viral fraction. Regarding the main aim of this study and according with the results that were obtained, use a combination of different ELISA test as a DIVA strategy is feasible when the vaccination is carry out with a subunit H5 vaccine. Also is possible to use the ELISA kit to detect Neuraminidase (either N1 or N2) as a DIVA concept in countries where H5N1 is present and the vaccination programs are done with H5N2 vaccine.

Equilibrium Modeling of Carbon Dioxide Adsorption on Zeolites

High pressure adsorption of carbon dioxide on zeolite 13X was investigated in the pressure range (0 to 4) Mpa and temperatures 298, 308 and 323K. The data fitting is accomplished with the Toth, UNILAN, Dubinin-Astakhov and virial adsorption models which are generally used for micro porous adsorbents such as zeolites. Comparison with experimental data from the literature indicated that the virial model would best determine results. These results may be partly attributed to the flexibility of the virial model which can accommodate as many constants as the data warrants.

Flow Characteristics of Pulp Liquid in Straight Ducts

An experimental investigation was performed on pulp liquid flow in straight ducts with a square cross section. Fully developed steady flow was visualized and the fiber concentration was obtained using a light-section method developed by the author et al. The obtained results reveal quantitatively, in a definite form, the distribution of the fiber concentration. From the results and measurements of pressure loss, it is found that the flow characteristics of pulp liquid in ducts can be classified into five patterns. The relationships among the distributions of mean and fluctuation of fiber concentration, the pressure loss and the flow velocity are discussed, and then the features for each pattern are extracted. The degree of nonuniformity of the fiber concentration, which is indicated by the standard deviation of its distribution, is decreased from 0.3 to 0.05 with an increase in the velocity of the tested pulp liquid from 0.4 to 0.8%.

Multiple Sensors and JPDA-IMM-UKF Algorithm for Tracking Multiple Maneuvering Targets

In this paper, we consider the problem of tracking multiple maneuvering targets using switching multiple target motion models. With this paper, we aim to contribute in solving the problem of model-based body motion estimation by using data coming from visual sensors. The Interacting Multiple Model (IMM) algorithm is specially designed to track accurately targets whose state and/or measurement (assumed to be linear) models changes during motion transition. However, when these models are nonlinear, the IMM algorithm must be modified in order to guarantee an accurate track. In this paper we propose to avoid the Extended Kalman filter because of its limitations and substitute it with the Unscented Kalman filter which seems to be more efficient especially according to the simulation results obtained with the nonlinear IMM algorithm (IMMUKF). To resolve the problem of data association, the JPDA approach is combined with the IMM-UKF algorithm, the derived algorithm is noted JPDA-IMM-UKF.

Physiological and Pathology Demographics of Veteran Rugby Athletes: Golden Oldies Rugby Festival

Recently, the health of retired National Football League players, particularly lineman has been investigated. A number of studies have reported increased cardiometabolic risk, premature ardiovascular disease and incidence of type 2 diabetes. Rugby union players have somatotypes very similar to National Football league players which suggest that rugby players may have similar health risks. The International Golden Oldies World Rugby Festival (GORF) provided a unique opportunity to investigate the demographics of veteran rugby players. METHODOLOGIES: A cross-sectional, observational study was completed using an online web-based questionnaire that consisted of medical history and physiological measures. Data analysis was completed using a one sample t-test (50yrs) and Chi-square test. RESULTS: A total of 216 veteran rugby competitors (response rate = 6.8%) representing 10 countries, aged 35-72 yrs (mean 51.2, S.D. ±8.0), participated in the online survey. As a group, the incidence of current smokers was low at 8.8% (avg 72.4 cigs/wk) whilst the percentage consuming alcohol was high (93.1% (avg 11.2 drinks/wk). Competitors reported the following top six chronic diseases/disorders; hypertension (18.6%), arthritis (OA/RA, 11.5%), asthma (9.3%), hyperlipidemia (8.2%), diabetes (all types, 7.5%) and gout (6%), there were significant differences between groups with regard to cancer (all types) and migraines. When compared to the Australian general population (Australian Bureau of Statistics data, n=18,000), GORF competitors had a Climstein Mike, Walsh Joe (corresponding author) and Burke Stephen School of Exercise Science, Australian Catholic University, 25A Barker Road, Strathfield, Sydney, NSW, 2016, Australia (e-mail: [email protected], [email protected], [email protected]). John Best is with Orthosports, 160 Belmore Rd., Randwick, Sydney,NSW 2031, Australia (e-mail: [email protected]). Heazlewood, Ian Timothy is with School of Environmental and Life Sciences, Faculty Education, Health and Science, Charles Darwin University, Precinct Yellow Building 2, Charles Darwin University, NT 0909, Australia (e-mail: [email protected]). Kettunen Jyrki Arcada University of Applied Sciences, Jan-Magnus Janssonin aukio 1, FI-00550, Helsinki, Finland (e-mail: [email protected]). Adams Kent is with California State University Monterey Bay, Kinesiology Department, 100 Campus Center, Seaside, CA., 93955, USA (email: [email protected]). DeBeliso Mark is with Department of Physical Education and Human Performance, Southern Utah University, 351 West University Blvd, Cedar City, Utah, USA (e-mail: [email protected]). significantly lower incidence of anxiety (p

Iterative Process to Improve Simple Adaptive Subdivision Surfaces Method with Butterfly Scheme

Subdivision surfaces were applied to the entire meshes in order to produce smooth surfaces refinement from coarse mesh. Several schemes had been introduced in this area to provide a set of rules to converge smooth surfaces. However, to compute and render all the vertices are really inconvenient in terms of memory consumption and runtime during the subdivision process. It will lead to a heavy computational load especially at a higher level of subdivision. Adaptive subdivision is a method that subdivides only at certain areas of the meshes while the rest were maintained less polygons. Although adaptive subdivision occurs at the selected areas, the quality of produced surfaces which is their smoothness can be preserved similar as well as regular subdivision. Nevertheless, adaptive subdivision process burdened from two causes; calculations need to be done to define areas that are required to be subdivided and to remove cracks created from the subdivision depth difference between the selected and unselected areas. Unfortunately, the result of adaptive subdivision when it reaches to the higher level of subdivision, it still brings the problem with memory consumption. This research brings to iterative process of adaptive subdivision to improve the previous adaptive method that will reduce memory consumption applied on triangular mesh. The result of this iterative process was acceptable better in memory and appearance in order to produce fewer polygons while it preserves smooth surfaces.

The use of a Bespoke Computer Game For Teaching Analogue Electronics

An implementation of a design for a game based virtual learning environment is described. The game is developed for a course in analogue electronics, and the topic is the design of a power supply. This task can be solved in a number of different ways, with certain constraints, giving the students a certain amount of freedom, although the game is designed not to facilitate trial-and error approach. The use of storytelling and a virtual gaming environment provides the student with the learning material in a MMORPG environment. The game is tested on a group of second year electrical engineering students with good results.

Optimal One Bit Time Reversal For UWB Impulse Radio In Multi-User Wireless Communications

In this paper, with the purpose of further reducing the complexity of the system, while keeping its temporal and spatial focusing performance, we investigate the possibility of using optimal one bit time reversal (TR) system for impulse radio ultra wideband multi-user wireless communications. The results show that, by optimally selecting the number of used taps in the pre-filter the optimal one bit TR system can outperform the full one bit TR system. In some cases, the temporal and spatial focusing performance of the optimal one bit TR system appears to be compatible with that of the original TR system. This is a significant result as the overhead cost is much lower than it is required in the original TR system.

On Solving Single-Period Inventory Model under Hybrid Uncertainty

Inventory decisional environment of short life-cycle products is full of uncertainties arising from randomness and fuzziness of input parameters like customer demand requiring modeling under hybrid uncertainty. Prior inventory models incorporating fuzzy demand have unfortunately ignored stochastic variation of demand. This paper determines an unambiguous optimal order quantity from a set of n fuzzy observations in a newsvendor inventory setting in presence of fuzzy random variable demand capturing both fuzzy perception and randomness of customer demand. The stress of this paper is in providing solution procedure that attains optimality in two steps with demand information availability in linguistic phrases leading to fuzziness along with stochastic variation. The first step of solution procedure identifies and prefers one best fuzzy opinion out of all expert opinions and the second step determines optimal order quantity from the selected event that maximizes profit. The model and solution procedure is illustrated with a numerical example.

Ornament as a Universal Language of Peace (Based On Comparative Analysis of Cultures of proto-Turkic Peoples and Indian Tribes of North America)

In this article, the authors reviewed and analyzed the survey materials similarities ornament proto-Turkic and northern Indians. The study examined the materials scientists - geneticists, archaeologists, anthropologists. Numerous studies of scientists from different directions once again prove the relevance of the topic. The authors approached the subject from an artistic side. The study authors have made the appropriate conclusions. This publication is based on the proceedings of the investigation.

Design and Development of Pico-hydro Generation System for Energy Storage Using Consuming Water Distributed to Houses

This paper describes the design and development of pico-hydro generation system using consuming water distributed to houses. Water flow in the domestic pipes has kinetic energy that potential to generate electricity for energy storage purposes in addition to the routine activities such as laundry, cook and bathe. The inherent water pressure and flow inside the pipe from utility-s main tank that used for those usual activities is also used to rotate small scale hydro turbine to drive a generator for electrical power generation. Hence, this project is conducted to develop a small scale hydro generation system using consuming water distributed to houses as an alternative electrical energy source for residential use.

Numerical Simulation of Cavitation and Aeration in Discharge Gated Tunnel of a Dam Based on the VOF Method

Cavitation, usually known as a destructive phenomenon, involves turbulent unsteady two-phase flow. Having such features, cavitating flows have been turned to a challenging topic in numerical studies and many researches are being done for better understanding of bubbly flows and proposing solutions to reduce its consequent destructive effects. Aeration may be regarded as an effective protection against cavitation erosion in many hydraulic structures, like gated tunnels. The paper concerns numerical simulation of flow in discharge gated tunnel of a dam using ing RNG k -ε model coupled with the volume of fluid (VOF) method and the zone which is susceptible of cavitation inception in the tunnel is predicted. In the second step, a vent is considered in the mentioned zone for aeration and the numerical simulation is done again to study the effects of aeration. The results show that aeration is an impressively useful method to exclude cavitation in mentioned tunnels.

A Computational Comparison between Revetec Engine and Conventional Internal Combustion Engines on the Indicated Torque

This paper investigates the effect of replacing crankshaft with cam on the indicated torque during compression and power strokes in internal combustion engines. A Cycloidal cam profile was used in Revetec engine to calculate and compare the torque to a conventional engine, using a computational method. Firstly, the cylinder pressure was calculated using Ferguson equation, and then the torque calculated depending on cylinder pressure values in every crank angle. the results showed that by using Cycloidal cam profile in Revetec engine the torque can increased by 14% compared with conventional engines, which means an increase in engine efficiency.

Degree and the Effect of Order in the Family on Violence against Women (VAW)

The purpose of this study attempts to emphasize the factors relating to intra-family relationships (order point of view) on violence against the women, For this purpose a survey technique on the sample size amounted 100 women of married of city of Ilam in country of Iran were considered. For measurement of violence against the women , the CTS scaled has been used .violence against the women be measured in four dimension ( emotional violence, psycho violence, physical violence, neglect violence). highest violence was related to emotional violence and after are as follow respectively : physical violence and neglect violence. The results showed that women have experienced the violence more than once during the last year, degree of order in family is high. Explanation result indicated that the order variables in family including collective thinking, empathy and communal co-circumstance have significant effects on violence against the women. Via multiple regression analysis variables of empathy, religious tenet and education of husband had significant effect on violence against women. In other words relationships among family effect on violence in family.

Synchronization for Impulsive Fuzzy Cohen-Grossberg Neural Networks with Time Delays under Noise Perturbation

In this paper, we investigate a class of fuzzy Cohen- Grossberg neural networks with time delays and impulsive effects. By virtue of stochastic analysis, Halanay inequality for stochastic differential equations, we find sufficient conditions for the global exponential square-mean synchronization of the FCGNNs under noise perturbation. In particular, the traditional assumption on the differentiability of the time-varying delays is no longer needed. Finally, a numerical example is given to show the effectiveness of the results in this paper.

Antibacterial Capacity of Plumeria alba Petals

Antibacterial activity of Plumeria alba (Frangipani) petals methanolic extracts were evaluated against Escherichia coli, Proteus vulgaris,Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus saprophyticus, Enterococcus faecalis and Serratia marcescens by using disk diffusion method. Concentration extracts (80 %) showed the highest inhibition zone towards Escherichia coli (14.3 mm). Frangipani extract also showed high antibacterial activity against Staphylococcus saprophyticus, Proteus vulgaris and Serratia marcescens, but not more than the zones of the positive control used. Comparison between two broad specrum antibiotics to frangipani extracts showed that the 80 % concentration extracts produce the same zone of inhibition as Streptomycin. Frangipani extracts showed no bacterial activity towards Klebsiella pneumoniae, Pseudomonas aeruginosa and Enterococcus faecalis. There are differences in the sensitivity of different bacteria to frangipani extracts, suggesting that frangipani-s potency varies between these bacteria. The present results indicate that frangipani showed significant antibacterial activity especially to Escherichia coli.

Behavior of Generated Gas in Lost Foam Casting

In the Lost Foam Casting process, melting point temperature of metal, as well as volume and rate of the foam degradation have significant effect on the mold filling pattern. Therefore, gas generation capacity and gas gap length are two important parameters for modeling of mold filling time of the lost foam casting processes. In this paper, the gas gap length at the liquidfoam interface for a low melting point (aluminum) alloy and a high melting point (Carbon-steel) alloy are investigated by the photography technique. Results of the photography technique indicated, that the gas gap length and the mold filling time are increased with increased coating thickness and density of the foam. The Gas gap lengths measured in aluminum and Carbon-steel, depend on the foam density, and were approximately 4-5 and 25-60 mm, respectively. By using a new system, the gas generation capacity for the aluminum and steel was measured. The gas generation capacity measurements indicated that gas generation in the Aluminum and Carbon-steel lost foam casting was about 50 CC/g and 3200 CC/g polystyrene, respectively.

Rotor Flow Analysis using Animplicit Harmonic Balance Method

This paper is an extension of a previous work where a diagonally implicit harmonic balance method was developed and applied to simulate oscillatory motions of pitching airfoil and wing. A more detailed study on the accuracy, convergence, and the efficiency of the method is carried out in the current paperby varying the number of harmonics in the solution approximation. As the main advantage of the method is itsusage for the design optimization of the unsteady problems, its application to more practical case of rotor flow analysis during forward flight is carried out and compared with flight test data and time-accurate computation results.