Abstract: Recently, the Field Programmable Gate Array (FPGA) technology offers the potential of designing high performance systems at low cost. The discrete wavelet transform has gained the reputation of being a very effective signal analysis tool for many practical applications. However, due to its computation-intensive nature, current implementation of the transform falls short of meeting real-time processing requirements of most application. The objectives of this paper are implement the Haar and Daubechies wavelets using FPGA technology. In addition, the Bit Error Rate (BER) between the input audio signal and the reconstructed output signal for each wavelet is calculated. From the BER, it is seen that the implementations execute the operation of the wavelet transform correctly and satisfying the perfect reconstruction conditions. The design procedure has been explained and designed using the stat-ofart Electronic Design Automation (EDA) tools for system design on FPGA. Simulation, synthesis and implementation on the FPGA target technology has been carried out.
Abstract: Mammalian genomes contain large number of
retroelements (SINEs, LINEs and LTRs) which could affect
expression of protein coding genes through associated transcription
factor binding sites (TFBS). Activity of the retroelement-associated
TFBS in many genes is confirmed experimentally but their global
functional impact remains unclear. Human SINEs (Alu repeats) and
mouse SINEs (B1 and B2 repeats) are known to be clustered in GCrich
gene rich genome segments consistent with the view that they
can contribute to regulation of gene expression. We have shown
earlier that Alu are involved in formation of cis-regulatory modules
(clusters of TFBS) in human promoters, and other authors reported
that Alu located near promoter CpG islands have an increased
frequency of CpG dinucleotides suggesting that these Alu are
undermethylated. Human Alu and mouse B1/B2 elements have an
internal bipartite promoter for RNA polymerase III containing
conserved sequence motif called B-box which can bind basal
transcription complex TFIIIC. It has been recently shown that TFIIIC
binding to B-box leads to formation of a boundary which limits
spread of repressive chromatin modifications in S. pombe. SINEassociated
B-boxes may have similar function but conservation of
TFIIIC binding sites in SINEs located near mammalian promoters
has not been studied earlier. Here we analysed abundance and
distribution of retroelements (SINEs, LINEs and LTRs) in annotated
sequences of the Database of mammalian transcription start sites
(DBTSS). Fractions of SINEs in human and mouse promoters are
slightly lower than in all genome but >40% of human and mouse
promoters contain Alu or B1/B2 elements within -1000 to +200 bp
interval relative to transcription start site (TSS). Most of these SINEs
is associated with distal segments of promoters (-1000 to -200 bp
relative to TSS) indicating that their insertion at distances >200 bp
upstream of TSS is tolerated during evolution. Distribution of SINEs
in promoters correlates negatively with the distribution of CpG
sequences. Using analysis of abundance of 12-mer motifs from the
B1 and Alu consensus sequences in genome and DBTSS it has been
confirmed that some subsegments of Alu and B1 elements are poorly
conserved which depends in part on the presence of CpG
dinucleotides. One of these CpG-containing subsegments in B1
elements overlaps with SINE-associated B-box and it shows better
conservation in DBTSS compared to genomic sequences. It has been
also studied conservation in DBTSS and genome of the B-box
containing segments of old (AluJ, AluS) and young (AluY) Alu
repeats and found that CpG sequence of the B-box of old Alu is
better conserved in DBTSS than in genome. This indicates that Bbox-
associated CpGs in promoters are better protected from
methylation and mutation than B-box-associated CpGs in genomic
SINEs. These results are consistent with the view that potential
TFIIIC binding motifs in SINEs associated with human and mouse
promoters may be functionally important. These motifs may protect
promoters from repressive histone modifications which spread from
adjacent sequences. This can potentially explain well known
clustering of SINEs in GC-rich gene rich genome compartments and
existence of unmethylated CpG islands.
Abstract: In mammalian reproductive tract, the oviduct secretes
huge number of growth factors and cytokines that create an optimal
micro-environment for the initial stages of preimplantation embryos.
Secretion of these growth factors is stage-specific. Among them,
VEGF is a potent mitogen for vascular endothelium and stimulates
vascular permeability. Apart from angiogenesis, VEGF in the oviduct
may be involved in regulating the oocyte maturation and subsequent
developmental process during embryo production in vitro. In
experiment 1, to evaluate the effect of VEGF during IVM of porcine
COC and subsequent developmental ability after PA and SCNT. The
results from these experiments indicated that maturation rates among
the different VEGF concentrations were not significant different. In
experiment 2, total intracellular GSH concentrations of oocytes
matured with VEGF (5-50 ng/ml) were increased significantly
compared to a control and VEGF group (500 ng/ml). In experiment 3,
the blastocyst formation rates and total cell number per blastocyst
after parthenogenesis of oocytes matured with VEGF (5-50 ng/ml)
were increased significantly compared to a control and VEGF group
(500 ng/ml). Similarly, in experiment 4, the blastocyst formation rate
and total cell number per blastocyst after SCNT and IVF of oocytes
matured with VEGF (5 ng/ml) were significantly higher than that of
oocytes matured without VEGF group. In experiment 5, at 10 hour
after the onset of IVF, pronuclear formation rate was evaluated.
Monospermy was significantly higher in VEGF-matured oocytes than
in the control, and polyspermy and sperm penetration per oocyte
were significantly higher in the control group than in the VEGFmatured
oocytes. Supplementation with VEGF during IVM
significantly improved male pronuclear formation as compared with
the control. In experiment 6, type III cortical granule distribution in
oocytes was more common in VEGF-matured oocytes than in the
control. In conclusion, the present study suggested that
supplementation of VEGF during IVM may enhance the
developmental potential of porcine in vitro embryos through increase
of the intracellular GSH level, higher MPN formation and increased
fertilization rate as a consequence of an improved cytoplasmic
maturation.
Abstract: Nano fibers produced by electrospinning are of industrial and scientific attention due to their special characteristics such as long length, small diameter and high surface area. Applications of electrospun structures in nanotechnology are included tissue scaffolds, fibers for drug delivery, composite reinforcement, chemical sensing, enzyme immobilization, membrane-based filtration, protective clothing, catalysis, solar cells, electronic devices and others. Many polymer and ceramic precursor nano fibers have been successfully electrospun with diameters in the range from 1 nm to several microns. The process is complex so that fiber diameter is influenced by various material, design and operating parameters. The objective of this work is to apply genetic algorithm on the parameters of electrospinning which have the most significant effect on the nano fiber diameter to determine the optimum parameter values before doing experimental set up. Effective factors including initial polymer concentration, initial jet radius, electrical potential, relaxation time, initial elongation, viscosity and distance between nozzle and collector are considered to determine finest diameter which is selected by user.
Abstract: The ongoing effort to develop an in-house
compressible solver with multi-disciplinary physics is presented in
this paper. Basic compressible solver combined with IBM technique
provides us an effective numerical tool able to tackle the physics
phenomena and especially physic phenomena involved in Solid
Rocket Motors (SRMs). Main principles are introduced step by step
describing its implementation. This paper sheds light on the whole
potentiality of our proposed numerical model and we strongly believe
a way to introduce multi-physics mechanisms strongly coupled is
opened to ablation in nozzle, fluid/structure interaction and burning
propellant surface with time.
Abstract: Schools today face ever-increasing demands in their attempts to ensure that students are well equipped to enter the workforce and navigate a complex world. Research indicates that computer technology can help support learning, implementation of various experiments or learning games, and that it is especially useful in developing the higher-order skills of critical thinking, observation, comprehension, implementation, comparison, analysis and active attention to activities such as research, field work, simulations and scientific inquiry. The ICT in education supports the learning procedure by enabling it to be more flexible and effective, create a rich and attractive training environment and equip the students with knowledge and potential useful for the competitive social environment in which they live. This paper presents the design, the development, and the results of the evaluation analysis of an interactive educational game which using real electric vehicles - toys (material) on a toy race track. When the game starts each student selects a specific vehicle toy. Then students are answering questionnaires in the computer. The vehicles' speed is related to the percentage of right answers in a multiple choice questionnaire (software). Every question has its own significant value depending of the different level of questionnaire. Via the developed software, each right or wrong answers in questionnaire increase or decrease the real time speed of their vehicle toys. Moreover the rate of vehicle's speed increase or decrease depends on the difficulty level of each question. The aim of the work is to attract the student’s interest in a learning process and also to improve their scores. The developed real time game was tested using independent populations of students of age groups: 8-10, 11-14, 15-18 years. Standard educational and statistical analysis tools were used for the evaluation analysis of the game. Results reveal that students using the developed real time control game scored much higher (60%) than students using a traditional simulation game on the same questionnaire. Results further indicate that student's interest in repeating the developed real time control gaming was far higher (70%) than the interest of students using a traditional simulation game.
Abstract: The use of plastic materials in agriculture causes
serious hazards to the environment. The introduction of biodegradable materials, which can be disposed directly into the soil
can be one possible solution to this problem. In the present research results of experimental tests carried out on biodegradable film
fabricated from natural waste (corn husk) are presented. The film was
characterized by Fourier transform infrared spectroscopy (FTIR),
differential scanning calorimeter (DSC), thermal gravimetric analysis
(TGA) and atomic force microscope (AFM) observation. The film is
shown to be readily degraded within 7-9 months under controlled soil
conditions, indicating a high biodegradability rate. The film
fabricated was use to produce biodegradable pot (BioPot) for
seedlings plantation. The introduction and the expanding use of
biodegradable materials represent a really promising alternative for
enhancing sustainable and environmentally friendly agricultural
activities.
Abstract: Particle swarm optimization (PSO) technique is applied to design the water distribution pipeline network. A simulation-optimization model is formulated with the objective of minimizing cost and is applied to a benchmark water distribution system optimization problem. The benchmark problem taken for the application of PSO technique to optimize the pipe size of the water distribution network is New York City water supply system problem. The results from the analysis infer that PSO is a potential alternative optimization technique when compared to other heuristic techniques for optimal sizing of water distribution systems.
Abstract: Air pollution is still considered as one of the major
environmental and health issues. There is enough research evidence
to show a strong relationship between exposure to air contaminants
and respiratory illnesses among children and adults. In this paper we
used the Copula approach to study a potential relationship between
selected air pollutants (PM10 and NO2) and hospital admissions for
respiratory diseases. Kendall-s tau and Spearman-s rho rank
correlation coefficients are calculated and used in Copula method.
This paper demonstrates that copulas can be used to provide
additional information as a measure of an association when compared
to the standard correlation coefficients. The results find a significant
correlation between the selected air pollutants and hospital
admissions for most of the selected respiratory illnesses.
Abstract: The objective of this study is to present the test
results of variable air volume (VAV) air conditioning system
optimized by two objective genetic algorithm (GA). The objective
functions are energy savings and thermal comfort. The optimal set
points for fuzzy logic controller (FLC) are the supply air temperature
(Ts), the supply duct static pressure (Ps), the chilled water
temperature (Tw), and zone temperature (Tz) that is taken as the
problem variables. Supply airflow rate and chilled water flow rate are
considered to be the constraints. The optimal set point values are
obtained from GA process and assigned into fuzzy logic controller
(FLC) in order to conserve energy and maintain thermal comfort in
real time VAV air conditioning system. A VAV air conditioning
system with FLC installed in a software laboratory has been taken for
the purpose of energy analysis. The total energy saving obtained in
VAV GA optimization system with FLC compared with constant air
volume (CAV) system is expected to achieve 31.5%. The optimal
duct static pressure obtained through Genetic fuzzy methodology
attributes to better air distribution by delivering the optimal quantity
of supply air to the conditioned space. This combination enhanced
the advantages of uniform air distribution, thermal comfort and
improved energy savings potential.
Abstract: The African Great Lakes Region refers to the zone
around lakes Victoria, Tanganyika, Albert, Edward, Kivu, and
Malawi. The main source of electricity in this region is hydropower
whose systems are generally characterized by relatively weak,
isolated power schemes, poor maintenance and technical deficiencies
with limited electricity infrastructures. Most of the hydro sources are
rain fed, and as such there is normally a deficiency of water during
the dry seasons and extended droughts. In such calamities fossil fuels
sources, in particular petroleum products and natural gas, are
normally used to rescue the situation but apart from them being nonrenewable,
they also release huge amount of green house gases to our
environment which in turn accelerates the global warming that has at
present reached an amazing stage. Wind power is ample, renewable,
widely distributed, clean, and free energy source that does not
consume or pollute water. Wind generated electricity is one of the
most practical and commercially viable option for grid quality and
utility scale electricity production. However, the main shortcoming
associated with electric wind power generation is fluctuation in its
output both in space and time. Before making a decision to establish
a wind park at a site, the wind speed features there should therefore
be known thoroughly as well as local demand or transmission
capacity. The main objective of this paper is to utilise monthly
average wind speed data collected from one prospective site within
the African Great Lakes Region to demonstrate that the available
wind power there is high enough to generate electricity. The mean
monthly values were calculated from records gathered on hourly
basis for a period of 5 years (2001 to 2005) from a site in Tanzania.
The documentations that were collected at a height of 2 m were
projected to a height of 50 m which is the standard hub height of
wind turbines. The overall monthly average wind speed was found to
be 12.11 m/s whereas June to November was established to be the
windy season as the wind speed during the session is above the
overall monthly wind speed. The available wind power density
corresponding to the overall mean monthly wind speed was evaluated
to be 1072 W/m2, a potential that is worthwhile harvesting for the
purpose of electric generation.
Abstract: Diesel Engines emit complex mixtures of inorganic
and organic compounds in the form of both solid and vapour phase
particles. Most of the particulates released are ultrafine nanoparticles
which are detrimental to human health and can easily enter the body
by respiration. The emissions standards on particulate matter release
from diesel engines are constantly upgraded within the European
Union and with future regulations based on the particles numbers
released instead of merely mass, the need for effective aftertreatment
devices will increase. Standard particulate filters in the form of wall
flow filters can have problems with high soot accumulation,
producing a large exhaust backpressure. A potential solution would
be to combine the standard filter with a flow through filter to reduce
the load on the wall flow filter. In this paper soot particle trapping has
been simulated in different continuous flow filters of monolithic
structure including the use of promoters, at laminar flow conditions.
An Euler Lagrange model, the discrete phase model in Ansys used
with user defined functions for forces acting on particles. A method
to quickly screen trapping of 5 nm and 10 nm particles in different
catalysts designs with tracers was also developed.
Simulations of square duct monoliths with promoters show that the
strength of the vortices produced are not enough to give a high
amount of particle deposition on the catalyst walls. The smallest
particles in the simulations, 5 and 10 nm particles were trapped to a
higher extent, than larger particles up to 1000 nm, in all studied
geometries with the predominant deposition mechanism being
Brownian diffusion. The comparison of the different filters designed
with a wall flow filter does show that the options for altering a design
of a flow through filter, without imposing a too large pressure drop
penalty are good.
Abstract: A new approach to predict the 3D structures of proteins by combining the knowledge-based method and Molecular Dynamics Simulation is presented on the chicken villin headpiece subdomain (HP-36). Comparative modeling is employed as the knowledge-based method to predict the core region (Ala9-Asn28) of the protein while the remaining residues are built as extended regions (Met1-Lys8; Leu29-Phe36) which then further refined using Molecular Dynamics Simulation for 120 ns. Since the core region is built based on a high sequence identity to the template (65%) resulting in RMSD of 1.39 Å from the native, it is believed that this well-developed core region can act as a 'nucleation center' for subsequent rapid downhill folding. Results also demonstrate that the formation of the non-native contact which tends to hamper folding rate can be avoided. The best 3D model that exhibits most of the native characteristics is identified using clustering method which then further ranked based on the conformational free energies. It is found that the backbone RMSD of the best model compared to the NMR-MDavg is 1.01 Å and 3.53 Å, for the core region and the complete protein, respectively. In addition to this, the conformational free energy of the best model is lower by 5.85 kcal/mol as compared to the NMR-MDavg. This structure prediction protocol is shown to be effective in predicting the 3D structure of small globular protein with a considerable accuracy in much shorter time compared to the conventional Molecular Dynamics simulation alone.
Abstract: Learning using labeled and unlabelled data has
received considerable amount of attention in the machine learning
community due its potential in reducing the need for expensive
labeled data. In this work we present a new method for combining
labeled and unlabeled data based on classifier ensembles. The model
we propose assumes each classifier in the ensemble observes the
input using different set of features. Classifiers are initially trained
using some labeled samples. The trained classifiers learn further
through labeling the unknown patterns using a teaching signals that is
generated using the decision of the classifier ensemble, i.e. the
classifiers self-supervise each other. Experiments on a set of object
images are presented. Our experiments investigate different classifier
models, different fusing techniques, different training sizes and
different input features. Experimental results reveal that the proposed
self-supervised ensemble learning approach reduces classification
error over the single classifier and the traditional ensemble classifier
approachs.
Abstract: Spatial understanding and the understanding of
dynamic change in the spatial structure of molecules during a
reaction is essential for designing new molecules. Knowing the
physical processes in the reactions helps to speed up the designing
process. To support the designer with the correct representation of
the designed molecule as well as showing the dynamic behavior of
the whole reacting system is the goal of our application. Our system
shows the spatial deformation of the molecules at every time interval
by minimizing the energy level of the molecules. The position and
orientation of the molecules can be intuitively controlled by
manipulating objects of the real world using Augmented Reality
techniques. Our approach has the potential to speed up the design of
new molecules and help students to understand the chemical
processes better.
Abstract: This paper considers the design of a motion planner
that will simultaneously accomplish control and motion planning of a
n-link nonholonomic mobile manipulator, wherein, a n-link
holonomic manipulator is coupled with a nonholonomic mobile
platform, within an obstacle-ridden environment. This planner,
derived from the Lyapunov-based control scheme, generates
collision-free trajectories from an initial configuration to a final
configuration in a constrained environment cluttered with stationary
solid objects of different shapes and sizes. We demonstrate the
efficiency of the control scheme and the resulting acceleration
controllers of the mobile manipulator with results through computer
simulations of an interesting scenario.
Abstract: A new design approach for three-stage operational
amplifiers (op-amps) is proposed. It allows to actually implement a
symmetrical push-pull class-AB amplifier output stage for wellestablished
three-stage amplifiers using a feedforward
transconductance stage. Compared with the conventional design
practice, the proposed approach leads to a significant
improvement of the symmetry between the positive and the
negative op-amp step response, resulting in similar values of the
positive/negative settling time. The new approach proves to be very
useful in order to fully exploit the potentiality allowed by the op-amp
in terms of speed performances. Design examples in a commercial
0.35-μm CMOS prove the effectiveness of theproposed strategy.
Abstract: Magnesium wastes are produced by many industrial activities. This waste problem is becoming a future problem for the world. Magnesium borates have many advantages such as; high corrosion resistance, heat resistance, high coefficient of elasticity and can also be used in the production of material against radiation. Addition, magnesium borates have great potential in sectors
including ceramic and detergents industry and superconducting materials.
In this study, using the starting materials of waste magnesium and H3BO3 the hydrothermal method was applied at a moderate
temperature of 70oC. Several mole ratios of waste magnesium to H3BO3 are selected as; 1:2, 1:4, 1:6, 1:8, 1:10. Reaction time was determined as 1 hour. After the synthesis, X-Ray Diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FT-IR) techniques are applied to products. As a result the forms of mcallisterite “Mg2(B6O7(OH)6)2.9(H2O)”, admontite “MgO(B2O3)3.7(H2O)” and magnesium boron hydrate (MgO(B2O3)3.6(H2O)” are obtained.
Abstract: Many problems in computer vision and image
processing present potential for parallel implementations through one
of the three major paradigms of geometric parallelism, algorithmic
parallelism and processor farming. Static process scheduling
techniques are used successfully to exploit geometric and algorithmic
parallelism, while dynamic process scheduling is better suited to
dealing with the independent processes inherent in the process
farming paradigm. This paper considers the application of parallel or
multi-computers to a class of problems exhibiting spatial data
characteristic of the geometric paradigm. However, by using
processor farming paradigm, a dynamic scheduling technique is
developed to suit the MIMD structure of the multi-computers. A
hybrid scheme of scheduling is also developed and compared with
the other schemes. The specific problem chosen for the investigation
is the Hough transform for line detection.
Abstract: Because road traffic accidents are a major source of death worldwide, attempts have been made to create Advanced Driver Assistance Systems (ADAS) able to detect vehicle, driver and
environmental conditions that are cues for possible potential accidents. This paper presents continued work on a novel Nonintrusive
Intelligent Driver Assistance and Safety System (Ni-DASS)
for assessing driver attention and hazard awareness. It uses two onboard
CCD cameras – one observing the road and the other observing
the driver-s face. The windscreen is divided into cells and analysis of
the driver-s eye-gaze patterns allows Ni-DASS to determine the windscreen cell the driver is focusing on using eye-gesture templates.
Intersecting the driver-s field of view through the observed
windscreen cell with subsections of the camera-s field of view containing a potential hazard allows Ni-DASS to estimate the
probability that the driver has actually observed the hazard. Results
have shown that the proposed technique is an accurate enough
measure of driver observation to be useful in ADAS systems.