Abstract: Mutations of the telomeric copy of the survival motor neuron 1 (SMN1) gene cause spinal muscular atrophy. A deletion of the Eef1a2 gene leads to lower motor neuron degeneration in wasted mice. Indirect evidences have been shown that the eEF1A protein family may interact with SMN, and our previous study showed that abnormalities of neuromuscular junctions in wasted mice were similar to those of Smn mutant mice. To determine potential colocalization between SMN and tissue-specific translation elongation factor 1A2 (eEF1A2), an immunochemical analysis of HeLa cells transfected with the plasmid pcDNA3.1(+)C-hEEF1A2- myc and a new quantitative test of colocalization by intensity correlation analysis (ICA) was used to explore the association of SMN and eEF1A2. Here the results showed that eEF1A2 redistributed from the cytoplasm to the nucleus in response to serum and epidermal growth factor. In the cytoplasm, compelling evidence showed that staining for myc-tagged eEF1A2 varied in synchrony with that for SMN, consistent with the formation of a SMN-eEF1A2 complex in the cytoplasm of HeLa cells. These findings suggest that eEF1A2 may colocalize with SMN in the cytoplasm and may be a component of the SMN complex. However, the limitation of the ICA method is an inability to resolve colocalization in components of small organelles such as the nucleus.
Abstract: Aspheric optical components are an alternative to the use of conventional lenses in the implementation of imaging systems for the visible range. Spherical lenses are capable of producing aberrations. Therefore, they are not able to focus all the light into a single point. Instead, aspherical lenses correct aberrations and provide better resolution even with compact lenses incorporating a small number of lenses.
Metrology of these components is very difficult especially when the resolution requirements increase and insufficient or complexity of conventional tools requires the development of specific approaches to characterization.
This work is part of the problem existed because the objectives are the study and comparison of different methods used to measure surface rays hybrid aspherical lenses.
Abstract: A key aspect of the design of any software system is
its architecture. An architecture description provides a formal model
of the architecture in terms of components and connectors and how
they are composed together. COSA (Component-Object based
Software Structures), is based on object-oriented modeling and
component-based modeling. The model improves the reusability by
increasing extensibility, evolvability, and compositionality of the
software systems. This paper presents the COSA modelling tool
which help architects the possibility to verify the structural coherence
of a given system and to validate its semantics with COSA approach.
Abstract: The paper shows some ability to manage two-phase
flows arising from the use of unsteady effects. In one case, we
consider the condition of fragmentation of the interface between the
two components leads to the intensification of mixing. The problem
is solved when the temporal and linear scale are small for the
appearance of the developed mixing layer. Showing that exist such
conditions for unsteady flow velocity at the surface of the channel,
which will lead to the creation and fragmentation of vortices at Re
numbers of order unity. Also showing that the Re is not a criterion of
similarity for this type of flows, but we can introduce a criterion that
depends on both the Re, and the frequency splitting of the vortices. It
turned out that feature of this situation is that streamlines behave
stable, and if we analyze the behavior of the interface between the
components it satisfies all the properties of unstable flows. The other
problem we consider the behavior of solid impurities in the extensive
system of channels. Simulated unsteady periodic flow modeled
breaths. Consider the behavior of the particles along the trajectories.
It is shown that, depending on the mass and diameter of the particles,
they can be collected in a caustic on the channel walls, stop in a
certain place or fly back. Of interest is the distribution of particle
velocity in frequency. It turned out that by choosing a behavior of the
velocity field of the carrier gas can affect the trajectory of individual
particles including force them to fly back.
Abstract: The paper focuses on the area of context modeling with respect to the specification of context-aware systems supporting ubiquitous applications. The proposed approach, followed within the SIMPLICITY IST project, uses a high-level system ontology to derive context models for system components which consequently are mapped to the system's physical entities. For the definition of user and device-related context models in particular, the paper suggests a standard-based process consisting of an analysis phase using the Common Information Model (CIM) methodology followed by an implementation phase that defines 3GPP based components. The benefits of this approach are further depicted by preliminary examples of XML grammars defining profiles and components, component instances, coupled with descriptions of respective ubiquitous applications.
Abstract: An investigation of noise in a micro stepping motor is
considered to study in this article. Because of the trend towards higher
precision and more and more small 3C (including Computer,
Communication and Consumer Electronics) products, the micro
stepping motor is frequently used to drive the micro system or the
other 3C products. Unfortunately, noise in a micro stepped motor is
too large to accept by the customs. To depress the noise of a micro
stepped motor, the dynamic characteristics in this system must be
studied. In this article, a Visual Basic (VB) computer program speed
controlled micro stepped motor in a digital camera is investigated.
Karman KD2300-2S non-contract eddy current displacement sensor,
probe microphone, and HP 35670A analyzer are employed to analyze
the dynamic characteristics of vibration and noise in a motor. The
vibration and noise measurement of different type of bearings and
different treatment of coils are compared. The rotating components,
bearings, coil, etc. of the motor play the important roles in producing
vibration and noise. It is found that the noise will be depressed about
3~4 dB and 6~7 dB, when substitutes the copper bearing with plastic
one and coats the motor coil with paraffin wax, respectively.
Abstract: Ozone (O3) is considered as one of the most
phytotoxic pollutants with deleterious effects on living and non living
components of Ecosystems. It reduces growth and yield of many
crops as well as alters the physiology and crop quality. The present
study described series of experiments to investigate the effects of
ambient O3 at different locations with different ambient levels of O3
depending on proximity to pollutant source and ranged between 17
ppb/h in control experiment to 112 ppb/h in industrial area
respectively. The ambient levels in other three locations (King Saud
University botanical garden, King Fahd Rd, and Almanakh Garden)
were 61,61,77 ppb/h respectively. Tow legume crops species (vicia
vaba L ; and Pisum sativum) differ in their phenology and sensitivity
were used. The results showed a significant negative effect to ozone
on morphology, number of injured leaves, growth and productivity
with a difference in the degree of response depending on the plant
type. Visia Faba showed sensitivity to ozone to number and leaf area
and the degree of injury leaves 3, pisum sativum show higher
sensitivity for the gas for degree of injury 1,The relative growth rate
and seed weight, it turns out there is no significant difference
between the two plants in plant height and number of seeds.
Abstract: Previous research has demonstrated that negative
attitudes towards people with physical disabilities and obesity are
predicted by a component of perceived vulnerability to disease; germ
aversion. These findings have been suggested as illustrations of an
evolved but over-active mechanism which promotes the avoidance of
pathogen-carrying individuals. To date, this interpretation of attitude
formation has not been explored with regard to people with
intellectual disability, and no attempts have been made to examine
possible mediating factors. This study examined attitudes in 333
adults and demonstrated that the moderate positive relationship
between germ aversion and negative attitudes toward people with
intellectual disability is fully mediated by social dominance
orientation, a general preference for hierarchies and inequalities
among social groups. These findings have implications for the
design of programs which attempt to promote community acceptance
and inclusion of people with disabilities.
Abstract: The ability to recognize humans and their activities by computer vision is a very important task, with many potential application. Study of human motion analysis is related to several research areas of computer vision such as the motion capture, detection, tracking and segmentation of people. In this paper, we describe a segmentation method for extracting human body contour in modified HLS color space. To estimate a background, the modified HLS color space is proposed, and the background features are estimated by using the HLS color components. Here, the large amount of human dataset, which was collected from DV cameras, is pre-processed. The human body and its contour is successfully extracted from the image sequences.
Abstract: The availability of water in adequate quantity and
quality is imperative for sustainable development. Worldwide,
significant imbalance exists with regards to sustainable development
particularly from a water and sanitation perspective. Water is a
critical component of public health, and failure to supply safe water
will place a heavy burden on the entire population. Although the 21st
century has witnessed wealth and advanced development, it has not
been realized everywhere. Billions of people are still striving to
access the most basic human needs which are food, shelter, safe
drinking water and adequate sanitation. The global picture conceals
various inequalities particularly with regards to sanitation coverage in
rural and urban areas. Currently, water scarcity and in particular
water governance is the main challenge which will cause a threat to
sustainable development goals. Within the context of water,
sanitation and health, sustainable development is a confusing concept
primarily when examined from the viewpoint of policy options for
developing countries. This perspective paper aims to summarize and
critically evaluate evidence of published studies in relation to water,
sanitation and health and to identify relevant solutions to reduce
public health impacts. Evidently, improving water and sanitation
services will result in significant and lasting gains in health and
economic development.
Abstract: Quantitative Investigation of impact of the factors' contribution towards measuring the reusability of software components could be helpful in evaluating the quality of developed or developing reusable software components and in identification of reusable component from existing legacy systems; that can save cost of developing the software from scratch. But the issue of the relative significance of contributing factors has remained relatively unexplored. In this paper, we have use the Taguchi's approach in analyzing the significance of different structural attributes or factors in deciding the reusability level of a particular component. The results obtained shows that the complexity is the most important factor in deciding the better Reusability of a function oriented Software. In case of Object Oriented Software, Coupling and Complexity collectively play significant role in high reusability.
Abstract: COSMED K4b2 is a portable electrical device designed to test pulmonary functions. It is ideal for many applications that need the measurement of the cardio-respiratory response either in the field or in the lab is capable with the capability to delivery real time data to a sink node or a PC base station with storing data in the memory at the same time. But the actual sensor outputs and data received may contain some errors, such as impulsive noise which can be related to sensors, low batteries, environment or disturbance in data acquisition process. These abnormal outputs might cause misinterpretations of exercise or living activities to persons being monitored. In our paper we propose an effective and feasible method to detect and identify errors in applications by principal component analysis (PCA) and a back propagation (BP) neural network.
Abstract: For several high speed networks, providing resilience against failures is an essential requirement. The main feature for designing next generation optical networks is protecting and restoring high capacity WDM networks from the failures. Quick detection, identification and restoration make networks more strong and consistent even though the failures cannot be avoided. Hence, it is necessary to develop fast, efficient and dependable fault localization or detection mechanisms. In this paper we propose a new fault localization algorithm for WDM networks which can identify the location of a failure on a failed lightpath. Our algorithm detects the failed connection and then attempts to reroute data stream through an alternate path. In addition to this, we develop an algorithm to analyze the information of the alarms generated by the components of an optical network, in the presence of a fault. It uses the alarm correlation in order to reduce the list of suspected components shown to the network operators. By our simulation results, we show that our proposed algorithms achieve less blocking probability and delay while getting higher throughput.
Abstract: An attempt was made to study of nitrogen
components response of corn (Zea mays L.) to drought stress. A farm
research was done in RCBD as split-plot with four replications in
Khorramabad, west Iran. Drought stress levels as irrigation regimes
after 75 (control), 100, and 120 (stress) mm cumulative evaporation
were in main plots, and four seed corn varieties include 500 (medium
maturity), 647, 700, and 704 (long maturity) were as subplots.
Soluble protein, nitrate and proline amino acid were measured in
shoot and root at flowering stage, and grain yield was measured in
harvesting stage. As the drought progressed, the amount of nitrate
and proline followed an increasing trend, but soluble protein
decreased in shoot and root. The highest amount of nitrate and
proline was observed in longer maturity varieties than shorter ones,
but decrease yield of long maturity varieties was higher than medium
maturity varieties in drought condition, because of long duration of
stress.
Abstract: Automated storage and retrieval systems (AS/RS)
become frequently used systems in warehouses. There has been a
transition from human based forklift applications to fast and safe
AS/RS applications in firm-s warehouse systems. In this study, basic
components and automation systems of the AS/RS are examined.
Proposed system's automation components and their tasks in the
system control algorithm were stated. According to this control
algorithm the control system structure was obtained.
Abstract: In face recognition, feature extraction techniques
attempts to search for appropriate representation of the data. However,
when the feature dimension is larger than the samples size, it brings
performance degradation. Hence, we propose a method called
Normalization Discriminant Independent Component Analysis
(NDICA). The input data will be regularized to obtain the most
reliable features from the data and processed using Independent
Component Analysis (ICA). The proposed method is evaluated on
three face databases, Olivetti Research Ltd (ORL), Face Recognition
Technology (FERET) and Face Recognition Grand Challenge
(FRGC). NDICA showed it effectiveness compared with other
unsupervised and supervised techniques.
Abstract: Several combinations of the preprocessing algorithms,
feature selection techniques and classifiers can be applied to the data
classification tasks. This study introduces a new accurate classifier,
the proposed classifier consist from four components: Signal-to-
Noise as a feature selection technique, support vector machine,
Bayesian neural network and AdaBoost as an ensemble algorithm.
To verify the effectiveness of the proposed classifier, seven well
known classifiers are applied to four datasets. The experiments show
that using the suggested classifier enhances the classification rates for
all datasets.
Abstract: The effects of seawater and slurry ice bleeding methods on the sensory, microbiological and chemical quality changes of cod fillets during chilled storage were examined in this study. The results from sensory evaluation showed that slurry ice bleeding method prolonged the shelf life of cod fillets up to 13-14 days compared to 10-11 days for fish bled in seawater. Slurry ice bleeding method also led to a slower microbial growth and biochemical developments, resulting lower total plate count (TPC), H2S-producing bacteria count, total volatile basic nitrogen (TVB-N), trimethylamine (TMA), free fatty acid (FFA) content and higher phospholipid content (PL) compared to those of samples bled in seawater. The results of principle component analysis revealed that TPC, H2S-producing bacteria, TVB-N, TMA and FFA were in significant correlation. They were also in negative correlation with sensory evaluation (Torry score), PL and water holding capacity (WHC).
Abstract: Following the laser ablation studies leading to a
theory of nuclei confinement by a Debye layer mechanism, we
present here numerical evaluations for the known stable nuclei where
the Coulomb repulsion is included as a rather minor component
especially for lager nuclei. In this research paper the required
physical conditions for the formation and stability of nuclei
particularly endothermic nuclei with mass number greater than to
which is an open astrophysical question have been investigated.
Using the Debye layer mechanism, nuclear surface energy, Fermi
energy and coulomb repulsion energy it is possible to find conditions
under which the process of nucleation is permitted in early universe.
Our numerical calculations indicate that about 200 second after the
big bang at temperature of about 100 KeV and subrelativistic region
with nucleon density nearly equal to normal nuclear density namely,
10cm all endothermic and exothermic nuclei have been
formed.
Abstract: Technology transfer of renewable energy technologies is very often unsuccessful in the developing world. Aside from challenges that have social, economic, financial, institutional and environmental dimensions, technology transfer has generally been misunderstood, and largely seen as mere delivery of high tech equipment from developed to developing countries or within the developing world from R&D institutions to society. Technology transfer entails much more, including, but not limited to: entire systems and their component parts, know-how, goods and services, equipment, and organisational and managerial procedures. Means to facilitate the successful transfer of energy technologies, including the sharing of lessons are subsequently extremely important for developing countries as they grapple with increasing energy needs to sustain adequate economic growth and development. Improving the success of technology transfer is an ongoing process as more projects are implemented, new problems are encountered and new lessons are learnt. Renewable energy is also critical to improve the quality of lives of the majority of people in developing countries. In rural areas energy is primarily traditional biomass. The consumption activities typically occur in an inefficient manner, thus working against the notion of sustainable development. This paper explores the implementation of technology transfer in the developing world (sub-Saharan Africa). The focus is necessarily on RETs since most rural energy initiatives are RETs-based. Additionally, it aims to highlight some lessons drawn from the cited RE projects and identifies notable differences where energy technology transfer was judged to be successful. This is done through a literature review based on a selection of documented case studies which are judged against the definition provided for technology transfer. This paper also puts forth research recommendations that might contribute to improved technology transfer in the developing world. Key findings of this paper include: Technology transfer cannot be complete without satisfying pre-conditions such as: affordability, maintenance (and associated plans), knowledge and skills transfer, appropriate know how, ownership and commitment, ability to adapt technology, sound business principles such as financial viability and sustainability, project management, relevance and many others. It is also shown that lessons are learnt in both successful and unsuccessful projects.