Abstract: Bioinformatics and Cheminformatics use computer as disciplines providing tools for acquisition, storage, processing, analysis, integrate data and for the development of potential applications of biological and chemical data. A chemical database is one of the databases that exclusively designed to store chemical information. NMRShiftDB is one of the main databases that used to represent the chemical structures in 2D or 3D structures. SMILES format is one of many ways to write a chemical structure in a linear format. In this study we extracted Antimicrobial Structures in SMILES format from NMRShiftDB and stored it in our Local Data Warehouse with its corresponding information. Additionally, we developed a searching tool that would response to user-s query using the JME Editor tool that allows user to draw or edit molecules and converts the drawn structure into SMILES format. We applied Quick Search algorithm to search for Antimicrobial Structures in our Local Data Ware House.
Abstract: This study was designed to investigate the role of serum nitric oxide and sialic acid in the development of diabetic nephropathy as disease marker. Total 210 diabetic patients (age and sex matched) were selected followed by informed consent and divided into four groups (70 each) as I: control; II: diabetic; III: diabetic hypertensive; IV: diabetic nephropathy. The blood samples of all subjects were collected and analyzed for serum nitric oxide, sialic acid, fasting blood glucose, serum urea, creatinine, HbA1c and GFR. The BMI, systolic and diastolic blood pressures, blood glucose, HbA1c and serum sialic acid levels were high (p
Abstract: Organochlorine pesticides (OCPs) are known to be
persistent and bioaccumulative toxicants that may cause reproductive
impairments in wildlife as well as human. The current study uses the
snail-eating turtle Malayemys macrocephala, a long-lived animal
commonly distribute in rice field habitat in central part of Thailand,
as a sentinel to monitor OCP contamination in environment. The
nest soil, complete clutch of eggs, and blood of the turtle were
collected from agricultural areas in the Chao Phraya River Basin,
Thailand during the nesting season of 2007-2008. The novel
methods for tissue extraction by an accelerated solvent extractor
(ASE, for egg) and liquid-liquid extraction (for blood) have been
developed. The nineteen OCP residues were analyzed by gas
chromatography with micro-electron captured detector (GC-μECD).
The validated methods have met requirements of the AOAC
standard. The results indicated that significant amounts of OCPs are
still contaminated in nest soil and eggs of the turtle even though the
OCPs had been banned in this area for many years. This suggested
the potential risk to health of wildlife as well as human in the area.
Abstract: In this paper we discuss a set of guidelines which
could be adapted when designing an audio user interface for the
visually impaired. It is based on an audio environment that is
focused on audio positioning. Unlike current applications which only
interpret Graphical User Interface (GUI) for the visually impaired,
this particular audio environment bypasses GUI to provide a direct
auditory output. It presents the capability of two dimensional (2D)
navigation on audio interfaces. This paper highlights the significance
of a 2D audio environment with spatial information in the context
of the visually impaired. A thorough usability study has been conducted
to prove the applicability of proposed design guidelines for
these auditory interfaces. While proving these guidelines, previously
unearthed design aspects have been revealed in this study.
Abstract: This paper deals with the problem of thermal and
mechanical shocks, which rising during operation, mostly at
interrupted cut. Here will be solved their impact on the cutting edge
tool life, the impact of coating technology on resistance to shocks
and experimental determination of tool life in heating flame.
Resistance of removable cutting edges against thermal and
mechanical shock is an important indicator of quality as well as its
abrasion resistance. Breach of the edge or its crumble may occur due
to cyclic loading. We can observe it not only during the interrupted
cutting (milling, turning areas abandoned hole or slot), but also in
continuous cutting. This is due to the volatility of cutting force on
cutting. Frequency of the volatility in this case depends on the type
of rising chips (chip size element). For difficult-to-machine materials
such as austenitic steel particularly happened at higher cutting speeds
for the localization of plastic deformation in the shear plane and for
the inception of separate elements substantially continuous chips.
This leads to variations of cutting forces substantially greater than for
other types of steel.
Abstract: A pilot project was carried out in 2007 by the senior
students of Cyprus International University, aiming to minimize the
total cost of waste collection in Northern Cyprus. Many developed
and developing countries have cut their transportation costs – which
lies between 30-40% – down at a rate of 40% percent, by
implementing network models for their route assignments.
Accordingly, a network model was implemented at Göçmenköy
district, to optimize and standardize waste collection works. The
work environment of the employees were also redesigned to provide
maximum ergonomy and to increase productivity, efficiency and
safety. Following the collection of the required data including waste
densities, lengths of roads and population, a model was constructed
to allocate the optimal route assignment for the waste collection
trucks at Göçmenköy district.
Abstract: Energy consumption is one of the indices in
determining the levels of development of a nation. Therefore,
availability of energy supply to all sectors of life in any country is
crucial for its development. These exists shortage of all kinds of
energy, particularly electricity which is badly needed for economic
development. Electricity from the sun which is quite abundant in
most of the developing countries is used in rural areas to meet basic
electricity needs of a rural community. Today-s electricity supply in
Myanmar is generated by fuel generators and hydroelectric power
plants. However, far-flung areas which are away from National Grids
cannot enjoy the electricity generated by these sources. Since
Myanmar is a land of plentiful sunshine, especially in central and
southern regions of the country, the first form of energy- solar energy
could hopefully become the final solution to its energy supply
problem. The direct conversion of solar energy into electricity using
photovoltaic system has been receiving intensive installation not only
in developed countries but also in developing countries. It is mainly
intended to present solar energy potential and application in
Myanmar. It is also wanted to get the benefits of using solar energy
for people in remote areas which are not yet connected to the national
grids because of the high price of fossil fuel.
Abstract: Caching was suggested as a solution for reducing bandwidth utilization and minimizing query latency in mobile environments. Over the years, different caching approaches have been proposed, some relying on the server to broadcast reports periodically informing of the updated data while others allowed the clients to request for the data whenever needed. Until recently a hybrid cache consistency scheme Scalable Asynchronous Cache Consistency Scheme SACCS was proposed, which combined the two different approaches benefits- and is proved to be more efficient and scalable. Nevertheless, caching has its limitations too, due to the limited cache size and the limited bandwidth, which makes the implementation of cache replacement strategy an important aspect for improving the cache consistency algorithms. In this thesis, we proposed a new cache replacement strategy, the Least Unified Value strategy (LUV) to replace the Least Recently Used (LRU) that SACCS was based on. This paper studies the advantages and the drawbacks of the new proposed strategy, comparing it with different categories of cache replacement strategies.
Abstract: In this paper a novel high output impedance, low input impedance, wide bandwidth, very simple current mirror with input and output voltage requirements less than that of a simple current mirror is presented. These features are achieved with very simple structure avoiding extra large node impedances to ensure high bandwidth operation. The circuit's principle of operation is discussed and compared to simple and low voltage cascode (LVC) current mirrors. Such outstanding features of this current mirror as high output impedance ~384K, low input impedance~6.4, wide bandwidth~178MHz, low input voltage ~ 362mV, low output voltage ~ 38mV and low current transfer error ~4% (all at 50μA) makes it an outstanding choice for high performance applications. Simulation results in BSIM 0.35μm CMOS technology with HSPICE are given in comparison with simple, and LVC current mirrors to verify and validate the performance of the proposed current mirror.
Abstract: Offset Double-Disk Opener (DDO) is a popular
furrow opener in conservation tillage. It has some limitations such as
negative suction to penetrate in the soil, hair pinning and mixing seed
and fertilizer in the slot. Because of importance of separation of seed
and fertilizer in the slot, by adding two horizontal mini disks to DDO
a modified opener was made (MDO) which placed the fertilizer
between and under two rows of seed. To consider performance of
novel opener an indoor comparison test between DDO and MDO was
performed at soil bin. The experiment was conducted with three
working speeds (3, 6 and 8 km h-1), two bulk densities of soil (1.1
and 1.4 Mg m-3) and two levels of residues (1 and 2 ton ha-1). The
experimental design consisted in a (3×2×2) complete randomized
factorial with three replicates for each test. Moisture of seed furrow,
separation of seed and fertilizer, hair pinning and resultant forces
acting on the openers were used as assessing indexes. There was no
significant difference between soil moisture content in slots created
by DDO and MDO at 0-4 cm depth, but at 4-8 cm the in the slot
created by MDO moisture content was higher about 9%. Horizontal
force for both openers increased with increasing speed and soil bulk
density. Vertical force for DDO was negative so it needed additional
weight for penetrating in the soil, but vertical force for MDO was
positive and, which can solve the challenge of penetration in the soil
in DDO. In soft soil with heavy residues some trash was pushed by
DDO into seed furrow (hair pinning) but at MDO seed were placed at
clean groove. Lateral and vertical separation of seed and fertilizer
was performed effectively by MDO (4.5 and 5 cm, respectively)
while DDO put seed and fertilizer close to each other. Overall, the
Modified Offset Double-disks (MDO) had better performance. So by
adapting this opener with no-tillage drillers it would possible to have
higher yield in conservation tillage where the most appropriate
opener is disk type.
Abstract: Domain-specific languages describe specific solutions to problems in the application domain. Traditionally they form a solution composing black-box abstractions together. This, usually, involves non-deep transformations over the target model. In this paper we argue that it is potentially powerful to operate with grey-box abstractions to build a domain-specific software system. We present parametric code templates as grey-box abstractions and conceptual tools to encapsulate and manipulate these templates. Manipulations introduce template-s merging routines and can be defined in a generic way. This involves reasoning mechanisms at the code templates level. We introduce the concept of Neurath Modelling Language (NML) that operates with parametric code templates and specifies a visualisation mapping mechanism for target models. Finally we provide an example of calculating a domain-specific software system with predefined NML elements.
Abstract: This paper introduces a framework that aims to
support the design and development of mobile services. The
traditional innovation process and its supporting instruments in form
of creativity tools, acceptance research and user-generated content
analysis are screened for potentials for improvement. The result is a
reshaped innovation process where acceptance research and usergenerated
content analysis are fully integrated within a creativity
tool. Advantages of this method are the enhancement of design
relevant information for developers and designers and the possibility
to forecast market success.
Abstract: The proper design of RF pulses in magnetic resonance imaging (MRI) has a direct impact on the quality of acquired images, and is needed for many applications. Several techniques have been proposed to obtain the RF pulse envelope given the desired slice profile. Unfortunately, these techniques do not take into account the limitations of practical implementation such as limited amplitude resolution. Moreover, implementing constraints for special RF pulses on most techniques is not possible. In this work, we propose to develop an approach for designing optimal RF pulses under theoretically any constraints. The new technique will pose the RF pulse design problem as a combinatorial optimization problem and uses efficient techniques from this area such as genetic algorithms (GA) to solve this problem. In particular, an objective function will be proposed as the norm of the difference between the desired profile and the one obtained from solving the Bloch equations for the current RF pulse design values. The proposed approach will be verified using analytical solution based RF simulations and compared to previous methods such as Shinnar-Le Roux (SLR) method, and analysis, selected, and tested the options and parameters that control the Genetic Algorithm (GA) can significantly affect its performance to get the best improved results and compared to previous works in this field. The results show a significant improvement over conventional design techniques, select the best options and parameters for GA to get most improvement over the previous works, and suggest the practicality of using of the new technique for most important applications as slice selection for large flip angles, in the area of unconventional spatial encoding, and another clinical use.
Abstract: The Neuro-Fuzzy hybridization scheme has become
of research interest in pattern classification over the past decade. The
present paper proposes a novel Modified Adaptive Fuzzy Inference
Engine (MAFIE) for pattern classification. A modified Apriori
algorithm technique is utilized to reduce a minimal set of decision
rules based on input output data sets. A TSK type fuzzy inference
system is constructed by the automatic generation of membership
functions and rules by the fuzzy c-means clustering and Apriori
algorithm technique, respectively. The generated adaptive fuzzy
inference engine is adjusted by the least-squares fit and a conjugate
gradient descent algorithm towards better performance with a
minimal set of rules. The proposed MAFIE is able to reduce the
number of rules which increases exponentially when more input
variables are involved. The performance of the proposed MAFIE is
compared with other existing applications of pattern classification
schemes using Fisher-s Iris and Wisconsin breast cancer data sets and
shown to be very competitive.
Abstract: This study was aimed for investigating of
manufacturing high aluminum content Mg alloys using a horizontal
twin roll caster. Recently, weight saving has been key issues for lighter
transport equipments as well as electronic component parts. As
alternative materials to aluminum alloys, developing magnesium alloy
with higher strength has been expected. Normally high Aluminum
content Mg alloy has poor ductility and is difficult to be rolled because
of its high strength. However, twin roll casting process is suitable for
manufacturing wrought Mg alloys because materials can be cast
directly from molten metal. In this study, manufacturing of high
aluminum content magnesium alloy sheet using the roll casting
process has been carried out. Effects of manufacturing parameter, such
as roll velocity, pouring temperature and roll gap, on casting was
investigated. A microscopic observation of the crystals of cross section
of as cast strip as well as rolled strip was conducted.
Abstract: The article analyses historical aspects of the formation
of the Kazakh nation in the conditions of the multicultural society.
The authors underline cultural integration as a significant stage of the
cultural advancement of the Kazakh nation. The transition to the
modern-style houses, the adoption and development of the secular
education gave a rise to the development of the society and culture
on the whole.
Abstract: This paper explores the scalability issues associated
with solving the Named Entity Recognition (NER) problem using
Support Vector Machines (SVM) and high-dimensional features. The
performance results of a set of experiments conducted using binary
and multi-class SVM with increasing training data sizes are
examined. The NER domain chosen for these experiments is the
biomedical publications domain, especially selected due to its
importance and inherent challenges. A simple machine learning
approach is used that eliminates prior language knowledge such as
part-of-speech or noun phrase tagging thereby allowing for its
applicability across languages. No domain-specific knowledge is
included. The accuracy measures achieved are comparable to those
obtained using more complex approaches, which constitutes a
motivation to investigate ways to improve the scalability of multiclass
SVM in order to make the solution more practical and useable.
Improving training time of multi-class SVM would make support
vector machines a more viable and practical machine learning
solution for real-world problems with large datasets. An initial
prototype results in great improvement of the training time at the
expense of memory requirements.
Abstract: As an effort to promote wind power industry in Korea,
Korea South-East Power Corporation has been developing 22MW
YeungHeung wind farm consisting of nine 2 to 3MW wind turbines
supplied by three manufacturers. To maximize its availability and
reliability and to solve the difficulty of operating three kinds of
SCADA systems, Korea Electric Power Corporation has been
developing a condition monitoring system integrated with control
functions. This paper presents the developed condition monitoring
system and its application to YeungHeung wind test bed, and the
design of its control functions.
Abstract: Data warehousing success is not high enough. User
dissatisfaction and failure to adhere to time frames and budgets are
too common. Most traditional information systems practices are
rooted in hard systems thinking. Today, the great systems thinkers
are forgotten by information systems developers. A data warehouse
is still a system and it is worth investigating whether systems
thinkers such as Churchman can enhance our practices today. This
paper investigates data warehouse development practices from a
systems thinking perspective. An empirical investigation is done in
order to understand the everyday practices of data warehousing
professionals from a systems perspective. The paper presents a
model for the application of Churchman-s systems approach in data
warehouse development.
Abstract: Dynamic location referencing method is an important technology to shield map differences. These method references objects of the road network by utilizing condensed selection of its real-world geographic properties stored in a digital map database, which overcomes the defections existing in pre-coded location referencing methods. The high attributes completeness requirements and complicated reference point selection algorithm are the main problems of recent researches. Therefore, a dynamic location referencing algorithm combining intersection points selected at the extremities compulsively and road link points selected according to link partition principle was proposed. An experimental system based on this theory was implemented. The tests using Beijing digital map database showed satisfied results and thus verified the feasibility and practicability of this method.