Abstract: This study focuses on examining why the range of
experience with respect to HIV infection is so diverse, especially in
regard to the latency period. An agent-based approach in modelling
the infection is used to extract high-level behaviour which cannot be
obtained analytically from the set of interaction rules at the cellular
level. A prototype model encompasses local variation in baseline
properties, contributing to the individual disease experience, and is
included in a network which mimics the chain of lymph nodes. The
model also accounts for stochastic events such as viral mutations.
The size and complexity of the model require major computational
effort and parallelisation methods are used.
Abstract: This study was conducted to determine the
objectivity, reliability and validity of the 90º push-ups test protocol
among male and female students of Sports Science Program, Faculty
of Sports Science and Coaching Sultan Idris University of Education.
Samples (n = 300), consisted of males (n = 168) and females (n =
132) students were randomly selected for this study. Researchers
tested the 90º push-ups on the sample twice in a single trial, test and
re-test protocol in the bench press test. Pearson-Product Moment
Correlation method's was used to determine the value of objectivity,
reliability and validity testing. The findings showed that the 900 pushups
test protocol showed high consistency between the two testers
with a value of r = .99. Likewise, The reliability value between test
and re-test for the 90º push-ups test for the male (r=.93) and female
(r=.93) students was also high. The results showed a correlation
between 90º push-ups test and bench press test for boys was r = .64
and girls was r = .28. This finding indicates that the use of the 90º
push-ups to test muscular strength and endurance in the upper body
of males has a higher validity values than female students.
Abstract: In this paper, we propose an approach of unsupervised
segmentation with fuzzy connectedness. Valid seeds are first specified
by an unsupervised method based on scale space theory. A region is
then extracted for each seed with a relative object extraction method of
fuzzy connectedness. Afterwards, regions are merged according to the
values between them of an introduced measure. Some theorems and
propositions are also provided to show the reasonableness of the
measure for doing mergence. Experiment results on a synthetic image,
a color image and a large amount of MR images of our method are
reported.
Abstract: Leonotisleonurus a shrub indigenous to Southern
Africa is widely used in traditional medicine to treat a variety of
conditions ranging from skin diseases and cough to epileptic fits and
‘heart problems’. Studies on the aqueous extract of the leaves have
indicated cycloxegenase enzyme inhibitory activity and an
antihypertensive effect.
Five methanol leaf extract fractions (MLEa - MLEe) of L.
leonurus were tested on anaesthetized normotensive male Wistar rats
(AWR) and isolated perfused working rat hearts (IWH). Fraction
MLEc (0.01mg/kg – 0.05mg/kg) induced significant increases in BP
and HR in AWR and positive chronotropic and inotropic effects in
IWH (1.0mg/ml – 5.0mg/ml). Pre-administration of atenolol
(2.0mg/kg) and prazosin (60μg/kg) significantly inhibited MLEc
effect on HR and MAP respectively in vivo, while atenolol
(7.0mg/ml) pre-perfusion significantly inhibited MLEc effect in vitro.
The hypertensive effect of MLEc is probably via β1agonism.
Results also indicate the presence of multiple cardioactive
compounds in L. leonurus.
Abstract: Ultra-low-power (ULP) circuits have received
widespread attention due to the rapid growth of biomedical
applications and Battery-less Electronics. Subthreshold region of
transistor operation is used in ULP circuits. Major research challenge
in the subthreshold operating region is to extract the ULP benefits
with minimal degradation in speed and robustness. Process, Voltage
and Temperature (PVT) variations significantly affect the
performance of subthreshold circuits. Designed performance
parameters of ULP circuits may vary largely due to temperature
variations. Hence, this paper investigates the effect of temperature
variation on device and circuit performance parameters at different
biasing voltages in the subthreshold region. Simulation results clearly
demonstrate that in deep subthreshold and near threshold voltage
regions, performance parameters are significantly affected whereas in
moderate subthreshold region, subthreshold circuits are more
immune to temperature variations. This establishes that moderate
subthreshold region is ideal for temperature immune circuits.
Abstract: Academic digital libraries emerged as a result of advances in computing and information systems technologies, and had been introduced in universities and to public. As results, moving in parallel with current technology in learning and researching environment indeed offers myriad of advantages especially to students and academicians, as well as researchers. This is due to dramatic changes in learning environment through the use of digital library system which giving spectacular impact on these societies- way of performing their study/research. This paper presents a survey of current criteria for evaluating academic digital libraries- performance. The goal is to discuss criteria being applied so far for academic digital libraries evaluation in the context of user-centered design. Although this paper does not comprehensively take into account all previous researches in evaluating academic digital libraries but at least it can be a guide in understanding the evaluation criteria being widely applied.
Abstract: Problem Statement:Rapid technological developments of the 21st century have advanced our daily lives in various ways. Particularly in education, students frequently utilize technological resources to aid their homework and to access information. listen to radio or watch television (26.9 %) and e-mails (34.2 %) [26]. Not surprisingly, the increase in the use of technologies also resulted in an increase in the use of e-mail, instant messaging, chat rooms, mobile phones, mobile phone cameras and web sites by adolescents to bully peers. As cyber bullying occurs in the cyber space, lesser access to technologies would mean lesser cyber-harm. Therefore, the frequency of technology use is a significant predictor of cyber bullying and cyber victims. Cyber bullies try to harm the victim using various media. These tools include sending derogatory texts via mobile phones, sending threatening e-mails and forwarding confidential emails to everyone on the contacts list. Another way of cyber bullying is to set up a humiliating website and invite others to post comments. In other words, cyber bullies use e-mail, chat rooms, instant messaging, pagers, mobile texts and online voting tools to humiliate and frighten others and to create a sense of helplessness. No matter what type of bullying it is, it negatively affects its victims. Children who bully exhibit more emotional inhibition and attribute themselves more negative self-statements compared to non-bullies. Students whose families are not sympathetic and who receive lower emotional support are more prone to bully their peers. Bullies have authoritarian families and do not get along well with them. The family is the place where the children-s physical, social and psychological needs are satisfied and where their personalities develop. As the use of the internet became prevalent so did parents- restrictions on their children-s internet use. However, parents are unaware of the real harm. Studies that explain the relationship between parental attitudes and cyber bullying are scarce in literature. Thus, this study aims to investigate the relationship between cyber bullying and parental attitudes in the primary school. Purpose of Study: This study aimed to investigate the relationship between cyber bullying and parental attitudes. A second aim was to determine whether parental attitudes could predict cyber bullying and if so which variables could predict it significantly. Methods:The study had a cross-sectional and relational survey model. A demographics information form, questions about cyber bullying and a Parental Attitudes Inventory were conducted with a total of 346 students (189 females and 157 males) registered at various primary schools. Data was analysed by multiple regression analysis using the software package SPSS 16.
Abstract: Equilibrium and stability equations of a thin rectangular plate with length a, width b, and thickness h(x)=C1x+C2, made of functionally graded materials under thermal loads are derived based on the first order shear deformation theory. It is assumed that the material properties vary as a power form of thickness coordinate variable z. The derived equilibrium and buckling equations are then solved analytically for a plate with simply supported boundary conditions. One type of thermal loading, uniform temperature rise and gradient through the thickness are considered, and the buckling temperatures are derived. The influences of the plate aspect ratio, the relative thickness, the gradient index and the transverse shear on buckling temperature difference are all discussed.
Abstract: In this paper a multi-objective nonlinear programming
model of cellular manufacturing system is presented which minimize
the intercell movements and maximize the sum of reliability of cells.
We present a genetic approach for finding efficient solutions to the
problem of cell formation for products having multiple routings.
These methods find the non-dominated solutions and according to
decision makers prefer, the best solution will be chosen.
Abstract: Mining Sequential Patterns in large databases has become
an important data mining task with broad applications. It is
an important task in data mining field, which describes potential
sequenced relationships among items in a database. There are many
different algorithms introduced for this task. Conventional algorithms
can find the exact optimal Sequential Pattern rule but it takes a
long time, particularly when they are applied on large databases.
Nowadays, some evolutionary algorithms, such as Particle Swarm
Optimization and Genetic Algorithm, were proposed and have been
applied to solve this problem. This paper will introduce a new kind
of hybrid evolutionary algorithm that combines Genetic Algorithm
(GA) with Particle Swarm Optimization (PSO) to mine Sequential
Pattern, in order to improve the speed of evolutionary algorithms
convergence. This algorithm is referred to as SP-GAPSO.
Abstract: Schema matching plays a key role in many different
applications, such as schema integration, data integration, data
warehousing, data transformation, E-commerce, peer-to-peer data
management, ontology matching and integration, semantic Web,
semantic query processing, etc. Manual matching is expensive and
error-prone, so it is therefore important to develop techniques to
automate the schema matching process. In this paper, we present a
solution for XML schema automated matching problem which
produces semantic mappings between corresponding schema
elements of given source and target schemas. This solution
contributed in solving more comprehensively and efficiently XML
schema automated matching problem. Our solution based on
combining linguistic similarity, data type compatibility and structural
similarity of XML schema elements. After describing our solution,
we present experimental results that demonstrate the effectiveness of
this approach.
Abstract: Grid computing is growing rapidly in the distributed
heterogeneous systems for utilizing and sharing large-scale resources
to solve complex scientific problems. Scheduling is the most recent
topic used to achieve high performance in grid environments. It aims
to find a suitable allocation of resources for each job. A typical
problem which arises during this task is the decision of scheduling. It
is about an effective utilization of processor to minimize tardiness
time of a job, when it is being scheduled. This paper, therefore,
addresses the problem by developing a general framework of grid
scheduling using dynamic information and an ant colony
optimization algorithm to improve the decision of scheduling. The
performance of various dispatching rules such as First Come First
Served (FCFS), Earliest Due Date (EDD), Earliest Release Date
(ERD), and an Ant Colony Optimization (ACO) are compared.
Moreover, the benefit of using an Ant Colony Optimization for
performance improvement of the grid Scheduling is also discussed. It
is found that the scheduling system using an Ant Colony
Optimization algorithm can efficiently and effectively allocate jobs
to proper resources.
Abstract: A new method for color image segmentation using fuzzy logic is proposed in this paper. Our aim here is to automatically produce a fuzzy system for color classification and image segmentation with least number of rules and minimum error rate. Particle swarm optimization is a sub class of evolutionary algorithms that has been inspired from social behavior of fishes, bees, birds, etc, that live together in colonies. We use comprehensive learning particle swarm optimization (CLPSO) technique to find optimal fuzzy rules and membership functions because it discourages premature convergence. Here each particle of the swarm codes a set of fuzzy rules. During evolution, a population member tries to maximize a fitness criterion which is here high classification rate and small number of rules. Finally, particle with the highest fitness value is selected as the best set of fuzzy rules for image segmentation. Our results, using this method for soccer field image segmentation in Robocop contests shows 89% performance. Less computational load is needed when using this method compared with other methods like ANFIS, because it generates a smaller number of fuzzy rules. Large train dataset and its variety, makes the proposed method invariant to illumination noise
Abstract: There are many automotive accidents due to blind spots and driver inattentiveness. Blind spot is the area that is invisible to the driver's viewpoint without head rotation. Several methods are available for assisting the drivers. Simplest methods are — rear mirrors and wide-angle lenses. But, these methods have a disadvantage of the requirement for human assistance. So, the accuracy of these devices depends on driver. Another approach called an automated approach that makes use of sensors such as sonar or radar. These sensors are used to gather range information. The range information will be processed and used for detecting the collision. The disadvantage of this system is — low angular resolution and limited sensing volumes. This paper is a panoramic sensor based automotive vehicle monitoring..
Abstract: The mechanical properties of granular solids are
dependent on the flow of stresses from one particle to another
through inter-particle contact. Although some experimental methods
have been used to study the inter-particle contacts in the past,
preliminary work with these techniques indicated that they do not
have the necessary resolution to distinguish between those contacts
that transmit the load and those that do not, especially for systems
with a wide distribution of particle sizes. In this research, computer
simulations are used to study the nature and distribution of contacts
in a compact with wide particle size distribution, representative of
aggregate size distribution used in asphalt pavement construction.
The packing fraction, the mean number of contacts and the
distribution of contacts were studied for different scenarios. A
methodology to distinguish and compute the fraction of load-bearing
particles and the fraction of space-filling particles (particles that do
not transmit any force) is needed for further investigation.
Abstract: A numerical study is presented on buckling and post
buckling behaviour of laminated carbon fiber reinforced plastic
(CFRP) thin-walled cylindrical shells under axial compression using
asymmetric meshing technique (AMT). Asymmetric meshing
technique is a perturbation technique to introduce disturbance without
changing geometry, boundary conditions or loading conditions.
Asymmetric meshing affects predicted buckling load, buckling mode
shape and post-buckling behaviour. Linear (eigenvalue) and nonlinear
(Riks) analyses have been performed to study the effect of
asymmetric meshing in the form of a patch on buckling behaviour.
The reduction in the buckling load using Asymmetric meshing
technique was observed to be about 15%. An isolated dimple formed
near the bifurcation point and the size of which increased to reach a
stable state in the post-buckling region. The load-displacement curve
behaviour applying asymmetric meshing is quite similar to the curve
obtained using initial geometric imperfection in the shell model.
Abstract: Type 2 diabetes mellitus (T2DM) is a complex
metabolic disorder that characterized by the presence of high glucose
in blood that cause from insulin resistance and insufficiency due to
deterioration β-cell Langerhans functions. T2DM is commonly
caused by the combination of inherited genetic variations as well as
our own lifestyle. Metallothionein (MT) is a known cysteine-rich
protein responsible in helping zinc homeostasis which is important in
insulin signaling and secretion as well as protection our body from
reactive oxygen species (ROS). MT scavenged ROS and free
radicals in our body happen to be one of the reasons of T2DM and its
complications. The objective of this study was to investigate the
association of MT1A and MT2A polymorphisms between T2DM and
control subjects among Malay populations. This study involved 150
T2DM and 120 Healthy individuals of Malay ethnic with mixed
genders. The genomic DNA was extracted from buccal cells and
amplified for MT1A and MT2A loci; the 347bp and 238bp banding
patterns were respectively produced by mean of the Polymerase
Chain Reaction (PCR). The PCR products were digested with Mlucl
and Tsp451 restriction enzymes respectively and producing
fragments lengths of (158/189/347bp) and (103/135/238bp)
respectively. The ANOVA test was conducted and it shown that there
was a significant difference between diabetic and control subjects for
age, BMI, WHR, SBP, FPG, HBA1C, LDL, TG, TC and family
history with (P0.05). The genotype
frequency for AA, AG and GG of MT1A polymorphisms was 72.7%,
22.7% and 4.7% in cases and 15%, 55% and 30% in control
respectively. As for MT2A, genotype frequency of GG, GC and CC
was 42.7%, 27.3% and 30% in case and 5%, 40% and 55% for
control respectively. Both polymorphisms show significant difference
between two investigated groups with (P=0.000). The Post hoc test
was conducted and shows a significant difference between the
genotypes within each polymorphism (P=0. 000). The MT1A and
MT2A polymorphisms were believed to be the reliable molecular
markers to distinguish the T2DM subjects from healthy individuals in
Malay populations.
Abstract: It has been established that microRNAs (miRNAs) play
an important role in gene expression by post-transcriptional regulation
of messengerRNAs (mRNAs). However, the precise relationships
between microRNAs and their target genes in sense of numbers,
types and biological relevance remain largely unclear. Dissecting the
miRNA-target relationships will render more insights for miRNA
targets identification and validation therefore promote the understanding
of miRNA function. In miRBase, miRanda is the key
algorithm used for target prediction for Zebrafish. This algorithm
is high-throughput but brings lots of false positives (noise). Since
validation of a large scale of targets through laboratory experiments
is very time consuming, several computational methods for miRNA
targets validation should be developed. In this paper, we present an
integrative method to investigate several aspects of the relationships
between miRNAs and their targets with the final purpose of extracting
high confident targets from miRanda predicted targets pool. This is
achieved by using the techniques ranging from statistical tests to
clustering and association rules. Our research focuses on Zebrafish.
It was found that validated targets do not necessarily associate with
the highest sequence matching. Besides, for some miRNA families,
the frequency of their predicted targets is significantly higher in the
genomic region nearby their own physical location. Finally, in a case
study of dre-miR-10 and dre-miR-196, it was found that the predicted
target genes hoxd13a, hoxd11a, hoxd10a and hoxc4a of dre-miR-
10 while hoxa9a, hoxc8a and hoxa13a of dre-miR-196 have similar
characteristics as validated target genes and therefore represent high
confidence target candidates.
Abstract: Proximate (moisture, protein, total fat, total ash) and mineral (K, P, Na, Mg, Ca, Zn, Fe, Cu and Mn) composition of chicken giblets (heart, liver and gizzard) were investigated. Phosphorous content, as well as proximate composition, were determined according to recommended ISO methods. The content of all elements, except phosphorus, of the giblets tissues were determined using inductively coupled plasma-optical emission spectrometry (ICP-OES), after dry ashing mineralization. Regarding proximate composition heart was the highest in total fat content, and the lowest in protein content. Liver was the highest in protein and total ash content, while gizzard was the highest in moisture and the lowest in total fat content. Regarding mineral composition liver was the highest for K, P, Ca, Mg, Fe, Zn, Cu, and Mn, while heart was the highest for Na content. The contents of almost all investigated minerals in analysed giblets tissues of chickens from Vojvodina were similar to values reported in the literature, i.e. in national food composition databases of other countries.
Abstract: In the multi objective optimization, in the case when generated set of Pareto optimal solutions is large, occurs the problem to select of the best solution from this set. In this paper, is suggested a method to order of Pareto set. Ordering the Pareto optimal set carried out in conformity with the introduced distance function between each solution and selected reference point, where the reference point may be adjusted to represent the preferences of a decision making agent. Preference information about objective weights from a decision maker may be expressed imprecisely. The developed elicitation procedure provides an opportunity to obtain surrogate numerical weights for the objectives, and thus, to manage impreciseness of preference. The proposed method is a scalable to many objectives and can be used independently or as complementary to the various visualization techniques in the multidimensional case.