Abstract: The similarity comparison of RNA secondary
structures is important in studying the functions of RNAs. In recent
years, most existing tools represent the secondary structures by
tree-based presentation and calculate the similarity by tree alignment
distance. Different to previous approaches, we propose a new method
based on maximum clique detection algorithm to extract the maximum
common structural elements in compared RNA secondary structures.
A new graph-based similarity measurement and maximum common
subgraph detection procedures for comparing purely RNA secondary
structures is introduced. Given two RNA secondary structures, the
proposed algorithm consists of a process to determine the score of the
structural similarity, followed by comparing vertices labelling, the
labelled edges and the exact degree of each vertex. The proposed
algorithm also consists of a process to extract the common structural
elements between compared secondary structures based on a proposed
maximum clique detection of the problem. This graph-based model
also can work with NC-IUB code to perform the pattern-based
searching. Therefore, it can be used to identify functional RNA motifs
from database or to extract common substructures between complex
RNA secondary structures. We have proved the performance of this
proposed algorithm by experimental results. It provides a new idea of
comparing RNA secondary structures. This tool is helpful to those
who are interested in structural bioinformatics.
Abstract: The seismic rehabilitation designs of two reinforced
concrete school buildings, representative of a wide stock of similar
edifices designed under earlier editions of the Italian Technical
Standards, are presented in this paper. The mutual retrofit solution
elaborated for the two buildings consists in the incorporation of a
dissipative bracing system including pressurized fluid viscous springdampers
as passive protective devices. The mechanical parameters,
layouts and locations selected for the constituting elements of the
system; the architectural renovation projects developed to properly
incorporate the structural interventions and improve the appearance
of the buildings; highlights of the installation works already
completed in one of the two structures; and a synthesis of the
performance assessment analyses carried out in original and
rehabilitated conditions, are illustrated. The results of the analyses
show a remarkable enhancement of the seismic response capacities of
both structures. This allows reaching the high performance objectives
postulated in the retrofit designs with much lower costs and
architectural intrusion as compared to traditional rehabilitation
interventions designed for the same objectives.
Abstract: This paper describes the NEAR (Navigating Exhibitions, Annotations and Resources) panel, a novel interactive visualization technique designed to help people navigate and interpret groups of resources, exhibitions and annotations by revealing hidden relations such as similarities and references. NEAR is implemented on A•VI•RE, an extended online information repository. A•VI•RE supports a semi-structured collection of exhibitions containing various resources and annotations. Users are encouraged to contribute, share, annotate and interpret resources in the system by building their own exhibitions and annotations. However, it is hard to navigate smoothly and efficiently in A•VI•RE because of its high capacity and complexity. We present a visual panel that implements new navigation and communication approaches that support discovery of implied relations. By quickly scanning and interacting with NEAR, users can see not only implied relations but also potential connections among different data elements. NEAR was tested by several users in the A•VI•RE system and shown to be a supportive navigation tool. In the paper, we further analyze the design, report the evaluation and consider its usage in other applications.
Abstract: Numerical analysis naturally finds applications in all
fields of engineering and the physical sciences, but in the
21st century, the life sciences and even the arts have adopted
elements of scientific computations. The numerical data analysis
became key process in research and development of all the fields [6].
In this paper we have made an attempt to analyze the specified
numerical patterns with reference to the association rule mining
techniques with minimum confidence and minimum support mining
criteria. The extracted rules and analyzed results are graphically
demonstrated. Association rules are a simple but very useful form of
data mining that describe the probabilistic co-occurrence of certain
events within a database [7]. They were originally designed to
analyze market-basket data, in which the likelihood of items being
purchased together within the same transactions are analyzed.
Abstract: Quality costs are the costs associated with preventing,
finding, and correcting defective work. Since the main language of
corporate management is money, quality-related costs act as means of
communication between the staff of quality engineering departments
and the company managers. The objective of quality engineering is to
minimize the total quality cost across the life of product. Quality
costs provide a benchmark against which improvement can be
measured over time. It provides a rupee-based report on quality
improvement efforts. It is an effective tool to identify, prioritize and
select quality improvement projects. After reviewing through the
literature it was noticed that a simplified methodology for data
collection of quality cost in a manufacturing industry was required.
The quantified standard methodology is proposed for collecting data
of various elements of quality cost categories for manufacturing
industry. Also in the light of research carried out so far, it is felt
necessary to standardise cost elements in each of the prevention,
appraisal, internal failure and external failure costs. . Here an attempt
is made to standardise the various cost elements applicable to
manufacturing industry and data is collected by using the proposed
quantified methodology. This paper discusses the case study carried
in luggage manufacturing industry.
Abstract: Growth and mineral nutrient elemental content were
studied in Mokara chark kuan pink terrestrial orchid and wild
Lantana camara weed agroecosystem. The treated subplots were
encircled with L. camara plants and sprayed weekly with L. camara
10% leaf aqueous extract. Allelopathic interactions were possible
through extensive invading root of L. camara plants into the treated
orchid subplots and weekly L. camara leaf aqueous extract
sprayings. Orchid growth was not significantly different in between
the control and treated plots, but chlorosis and yellowish patches of
leaves were observed in control orchid leaves. Nitrogen content in L.
camara leaf was significantly higher than in orchid leaf, the order of
importance of mineral nutrient contents in L. camara leaf was
K>Mg>Na>N. In treated orchid leaf, the order of importance was
N>K>Mg>Na. Orchid leaf N content from the treated plot was
higher than control, but Mg and Na contents were almost similar.
Abstract: Software maintenance and mainly software
comprehension pose the largest costs in the software lifecycle. In
order to assess the cost of software comprehension, various
complexity measures have been proposed in the literature. This paper
proposes new cognitive-spatial complexity measures, which combine
the impact of spatial as well as architectural aspect of the software to
compute the software complexity. The spatial aspect of the software
complexity is taken into account using the lexical distances (in
number of lines of code) between different program elements and the
architectural aspect of the software complexity is taken into
consideration using the cognitive weights of control structures
present in control flow of the program. The proposed measures are
evaluated using standard axiomatic frameworks and then, the
proposed measures are compared with the corresponding existing
cognitive complexity measures as well as the spatial complexity
measures for object-oriented software. This study establishes that the
proposed measures are better indicators of the cognitive effort
required for software comprehension than the other existing
complexity measures for object-oriented software.
Abstract: When the Malaysian government announced the implementation of the Build-Then-Sell (BTS) system in 2007, the proponents of the BTS have argued that the implementation of this new system may provide houses with low defects. However, there has been no empirical data to support their argument. Therefore, this study is conducted to measure the level of housing defects in the BTS housing delivery system. A survey was conducted to the occupiers in six BTS residential areas. The BTS residential areas have been identified through the media and because of the small number of population, all households in the BTS residential areas were required to participate in the study to enable the researcher to collect the data concerning defects. Questionnaire had been employed as the data collection instrument and was distributed to the respondents of this study. The result has shown that the level of defects in the BTS houses is low, as the rate of defects for all elements are slight. Such low level of defects has apparently only affected the aesthetic value of the houses.
Abstract: Measurement and the following evaluation of
performance represent important part of management. The paper
focuses on indicators as the basic elements of performance
measurement system. It emphasizes a necessity of searching
requirements for quality indicators so that they can become part of
the useful system. It introduces standpoints for a systematic dividing
of indicators so that they have as high as possible informative value
of background sources for searching, analysis, designing and using of
indicators. It draws attention to requirements for indicators' quality
and at the same it deals with some dangers decreasing indicator's
informative value. It submits a draft of questions that should be
answered at the construction of indicator. It is obvious that particular
indicators need to be defined exactly to stimulate the desired
behavior in order to attain expected results. In the enclosure a
concrete example of the defined indicator in the concrete conditions
of a small firm is given. The authors of the paper pay attention to the
fact that a quality indicator makes it possible to get to the basic
causes of the problem and include the established facts into the
company information system. At the same time they emphasize that
developing of a quality indicator is a prerequisite for the utilization
of the system of measurement in management.
Abstract: The nature, prevalence, cellular composition of
leukocyte infiltrates and immunohistochemical characteristics of
their constituent cells in the liver of patients with chronic viral
hepatitis B and C were investigated. It was found that the area of
distribution and cellular composition of infiltrates depended on the
virus type and process activity. The expediency of
immunohistochemical study using leukocyte infiltrates from liver
biopsies of patients with viral hepatitis aimed at clarifying diagnosis,
making prognosis, and choice of optimal treatment with elements of
immune correction is emphasized.
Abstract: Campus sustainability is the goal of a university striving for sustainable development. This study found that of 17 popular approaches, two comprehensive campus sustainability assessment frameworks were developed in the context of Sustainability in Higher Education (SHE), and used by many university campuses around the world. Sustainability Tracking Assessment and Rating Systems (STARS) and the Campus Sustainability Assessment Framework (CSAF) approaches are more comprehensive than others. Therefore, the researchers examined aspects and elements used by CSAF and STARS in the approach to develop a campus sustainability assessment framework for Universiti Kebangsaan Malaysia (UKM). Documents analysis found that CSAF and STARS do not focus on physical development, especially the construction industry, as key elements of campus sustainability assessment. This finding is in accordance with the Sustainable UKM Programme which consists of three main components of sustainable community, ecosystem and physical development.
Abstract: In biological and biomedical research motif finding tools are important in locating regulatory elements in DNA sequences. There are many such motif finding tools available, which often yield position weight matrices and significance indicators. These indicators, p-values and E-values, describe the likelihood that a motif alignment is generated by the background process, and the expected number of occurrences of the motif in the data set, respectively. The various tools often estimate these indicators differently, making them not directly comparable. One approach for comparing motifs from different tools, is computing the E-value as the product of the p-value and the number of possible alignments in the data set. In this paper we explore the combinatorics of the motif alignment models OOPS, ZOOPS, and ANR, and propose a generic algorithm for computing the number of possible combinations accurately. We also show that using the wrong alignment model can give E-values that significantly diverge from their true values.
Abstract: The vibrations produced by a single point defect on
various parts of the bearing under constant radial load are predicted
by using a theoretical model. The model includes variation in the
response due to the effect of bearing dimensions, rotating frequency
distribution of load. The excitation forces are generated when the
defects on the races strike to rolling elements. In case of the outer
ring defect, the pulses generated are with periodicity of outer ring
defect frequency where as for inner ring defect, the pulses are with
periodicity of inner ring defect frequency. The effort has been carried
out in preparing the physical model of the system. Different defect
frequencies are obtained and are used to find out the amplitudes of
the vibration due to excitation of the bearing parts. Increase in the
radial load or severity of the defect produces a significant change in
bearing signature characteristics.
Abstract: In this paper we present a novel design of a wearable
electronic textile. After defining a special application, we used the
specifications of some low power, tiny elements including sensors,
microcontrollers, transceivers, and a fault tolerant special topology to
have the most reliability as well as low power consumption and
longer lifetime. We have considered two different conditions as
normal and bodily critical conditions and set priorities for using
different sensors in various conditions to have a longer effective
lifetime.
Abstract: One part of the total employee-s reward is apart from basic wages or salary, employee-s benefits and intangible elements also so called contingent (variable) pay. Contingent pay is connected to performance, contribution, capcompetency or skills of individual employees, and to team-s or company-wide performance or to combination of few of the mentioned possibilities. Main aim of this article is to define, based on available information, contingent pay, describe reasons for its implementation and arguments for and against this type of remuneration, but also bring information not only about its extent and level of utilization by organizations of the Czech Republic operating in the field of environmental protection, but also mention their practical experience with this type of remuneration.
Abstract: This study examines the inelastic behavior of adjacent planar reinforced concrete (R.C.) frames subjected to strong ground motions. The investigation focuses on the effects of vertical ground motion on the seismic pounding. The examined structures are modeled and analyzed by RUAUMOKO dynamic nonlinear analysis program using reliable hysteretic models for both structural members and contact elements. It is found that the vertical ground motion mildly affects the seismic response of adjacent buildings subjected to structural pounding and, for this reason, it can be ignored from the displacement and interstorey drifts assessment. However, the structural damage is moderately affected by the vertical component of earthquakes.
Abstract: The Institute of Product Development is dealing
with the development, design and dimensioning of micro components
and systems as a member of the Collaborative Research
Centre 499 “Design, Production and Quality Assurance of
Molded micro components made of Metallic and Ceramic Materials".
Because of technological restrictions in the miniaturization
of conventional manufacturing techniques, shape and
material deviations cannot be scaled down in the same proportion
as the micro parts, rendering components with relatively
wide tolerance fields. Systems that include such components
should be designed with this particularity in mind, often requiring
large clearance. On the end, the output of such systems
results variable and prone to dynamical instability. To save
production time and resources, every study of these effects
should happen early in the product development process and
base on computer simulation to avoid costly prototypes. A
suitable method is proposed here and exemplary applied to a
micro technology demonstrator developed by the CRC499. It
consists of a one stage planetary gear train in a sun-planet-ring
configuration, with input through the sun gear and output
through the carrier. The simulation procedure relies on ordinary
Multi Body Simulation methods and subsequently adds
other techniques to further investigate details of the system-s
behavior and to predict its response. The selection of the relevant
parameters and output functions followed the engineering
standards for regular sized gear trains. The first step is to
quantify the variability and to reveal the most critical points of
the system, performed through a whole-mechanism Sensitivity
Analysis. Due to the lack of previous knowledge about the system-s
behavior, different DOE methods involving small and
large amount of experiments were selected to perform the SA.
In this particular case the parameter space can be divided into
two well defined groups, one of them containing the gear-s profile
information and the other the components- spatial location.
This has been exploited to explore the different DOE techniques
more promptly. A reduced set of parameters is derived for
further investigation and to feed the final optimization process,
whether as optimization parameters or as external perturbation
collective. The 10 most relevant perturbation factors and 4 to 6
prospective variable parameters are considered in a new, simplified
model. All of the parameters are affected by the mentioned
production variability. The objective functions of interest
are based on scalar output-s variability measures, so the
problem becomes an optimization under robustness and reliability constrains. The study shows an initial step on the development
path of a method to design and optimize complex micro
mechanisms composed of wide tolerated elements accounting
for the robustness and reliability of the systems- output.
Abstract: Integral Abutment Bridges (IAB) are defined as
simple or multiple span bridges in which the bridge deck is cast
monolithically with the abutment walls. This kind of bridges are
becoming very popular due to different aspects such as good
response under seismic loading, low initial costs, elimination of
bearings, and less maintenance. However the main issue related to
the analysis of this type of structures is dealing with soil-structure
interaction of the abutment walls and the supporting piles. Various
soil constitutive models have been used in studies of soil-structure
interaction in this kind of structures by researchers. This paper is an
effort to review the implementation of various finite elements model
which explicitly incorporates the nonlinear soil and linear structural
response considering various soil constitutive models and finite
element mesh.
Abstract: "Bazaar" is a Persian word from the language of Iranians of 2500 years ago which has entered the languages of other countries. “Bazaar", the trading or marketing place with the architectural principles and concerns, was formed in Iran because of the long experience of marketing. This has become a valuable inheritance of Islamic ideological civilization and Iranian advanced architecture and a model of Islamic-marketing places with spectacular elements and parts, and the place for economical, social and cultural exchanges. “Bazaars" are found in cities of Iran and many Islamic countries in west of Asia and north of Africa. With the stable structure and function as a symbol of social values, this place has become the economic center and the illustration of stable architecture and advanced principles. “Bazaars" as the heart of Iranian cities economy with several major and minor rows of shops, in closed and open areas, along a fixed line or branches with beautiful arcs, patios, and frameworks are among the main national inheritance of Iran and one of the important Iranian architectural treasures because of its Iranian nobility.
Abstract: This paper features the proposed modeling and design
of a Robust Decentralized Periodic Output Feedback (RDPOF)
control technique for the active vibration control of smart flexible
multimodel Euler-Bernoulli cantilever beams for a multivariable
(MIMO) case by retaining the first 6 vibratory modes. The beam
structure is modeled in state space form using the concept of
piezoelectric theory, the Euler-Bernoulli beam theory and the Finite
Element Method (FEM) technique by dividing the beam into 4 finite
elements and placing the piezoelectric sensor / actuator at two finite
element locations (positions 2 and 4) as collocated pairs, i.e., as
surface mounted sensor / actuator, thus giving rise to a multivariable
model of the smart structure plant with two inputs and two outputs.
Five such multivariable models are obtained by varying the
dimensions (aspect ratios) of the aluminum beam, thus giving rise to
a multimodel of the smart structure system. Using model order
reduction technique, the reduced order model of the higher order
system is obtained based on dominant eigen value retention and the
method of Davison. RDPOF controllers are designed for the above 5
multivariable-multimodel plant. The closed loop responses with the
RDPOF feedback gain and the magnitudes of the control input are
observed and the performance of the proposed multimodel smart
structure system with the controller is evaluated for vibration control.