Characterization of Liver Leukocyte Infiltrates and Features of Cytokine Profile under Viral Hepatitis-Induced Immunosuppression
The nature, prevalence, cellular composition of
leukocyte infiltrates and immunohistochemical characteristics of
their constituent cells in the liver of patients with chronic viral
hepatitis B and C were investigated. It was found that the area of
distribution and cellular composition of infiltrates depended on the
virus type and process activity. The expediency of
immunohistochemical study using leukocyte infiltrates from liver
biopsies of patients with viral hepatitis aimed at clarifying diagnosis,
making prognosis, and choice of optimal treatment with elements of
immune correction is emphasized.
[1] K.H. Meyer zum Buschenfelde "Immunopathology of chronic liver
diseases ", Verh. Dtsch. Ges. Pathol., vol. 79, 1995, pp. 186-197.
[2] M. Muller, H.E. Blum, F. Er, R. Thimme, N. Semmo "Cellular immune
response in hepatitis C infection: Role of CD154 expression and clinical
relevance", Dtsch. Med. Wochenschr., vol. 136(20), 2011, pp. 1073-
1077.
[3] A. Weber, Y.T. Boege, F. Reisinger, M. Heikenwälder "Chronic liver
inflammation and hepatocellular carcinoma: persistence matters", Swiss.
Med. Wkly., vol. 141, 2011, pp. 1-9
[1] K.H. Meyer zum Buschenfelde "Immunopathology of chronic liver
diseases ", Verh. Dtsch. Ges. Pathol., vol. 79, 1995, pp. 186-197.
[2] M. Muller, H.E. Blum, F. Er, R. Thimme, N. Semmo "Cellular immune
response in hepatitis C infection: Role of CD154 expression and clinical
relevance", Dtsch. Med. Wochenschr., vol. 136(20), 2011, pp. 1073-
1077.
[3] A. Weber, Y.T. Boege, F. Reisinger, M. Heikenwälder "Chronic liver
inflammation and hepatocellular carcinoma: persistence matters", Swiss.
Med. Wkly., vol. 141, 2011, pp. 1-9
@article{"International Journal of Medical, Medicine and Health Sciences:58202", author = "Olga V. Lebedinskaya and Irina N. Kabanovskaya and Anna S. Lasareva and Nelly K. Akhmatova and Anatoliy P. Godovalov and Andrey V. Horinko and Mikhail V. Kiselevsky", title = "Characterization of Liver Leukocyte Infiltrates and Features of Cytokine Profile under Viral Hepatitis-Induced Immunosuppression", abstract = "The nature, prevalence, cellular composition of
leukocyte infiltrates and immunohistochemical characteristics of
their constituent cells in the liver of patients with chronic viral
hepatitis B and C were investigated. It was found that the area of
distribution and cellular composition of infiltrates depended on the
virus type and process activity. The expediency of
immunohistochemical study using leukocyte infiltrates from liver
biopsies of patients with viral hepatitis aimed at clarifying diagnosis,
making prognosis, and choice of optimal treatment with elements of
immune correction is emphasized.", keywords = "Viral hepatitis, leukocyte infiltration, immunohistochemical characteristics, immunosupression.", volume = "6", number = "12", pages = "677-4", }