Abstract: The present investigation was aimed to develop methodology for the standardization of Marichyadi Vati and its raw materials. Standardization was carried using systematic Pharmacognostical and physicochemical parameters as per WHO guidelines. The detailed standardization of Marichyadi Vati, it is concluded that there are no major differences prevailed in the quality of marketed products and laboratory samples of Marichyadi Vati. However, market samples showed slightly better amount of Piperine than the laboratory sample by both methods. This is the first attempt to generate complete set of standards required for the Marichyadi Vati.
Abstract: MRAM technology provides a combination of fast
access time, non-volatility, data retention and endurance. While a
growing interest is given to two-terminal Magnetic Tunnel Junctions
(MTJ) based on Spin-Transfer Torque (STT) switching as the
potential candidate for a universal memory, its reliability is
dramatically decreased because of the common writing/reading path.
Three-terminal MTJ based on Spin-Orbit Torque (SOT) approach
revitalizes the hope of an ideal MRAM. It can overcome the
reliability barrier encountered in current two-terminal MTJs by
separating the reading and the writing path. In this paper, we study
two possible writing schemes for the SOT-MTJ device based on
recently fabricated samples. While the first is based on precessional
switching, the second requires the presence of permanent magnetic
field. Based on an accurate Verilog-A model, we simulate the two
writing techniques and we highlight advantages and drawbacks of
each one. Using the second technique, pioneering logic circuits based
on the three-terminal architecture of the SOT-MTJ described in this
work are under development with preliminary attractive results.
Abstract: The goal of Gene Expression Analysis is to understand the processes that underlie the regulatory networks and pathways controlling inter-cellular and intra-cellular activities. In recent times microarray datasets are extensively used for this purpose. The scope of such analysis has broadened in recent times towards reconstruction of gene networks and other holistic approaches of Systems Biology. Evolutionary methods are proving to be successful in such problems and a number of such methods have been proposed. However all these methods are based on processing of genotypic information. Towards this end, there is a need to develop evolutionary methods that address phenotypic interactions together with genotypic interactions. We present a novel evolutionary approach, called Phenomic algorithm, wherein the focus is on phenotypic interaction. We use the expression profiles of genes to model the interactions between them at the phenotypic level. We apply this algorithm to the yeast sporulation dataset and show that the algorithm can identify gene networks with relative ease.
Abstract: The first and basic cause of the failure of concrete is repeated freezing (thawing) of moisture contained in the pores, microcracks, and cavities of the concrete. On transition to ice, water existing in the free state in cracks increases in volume, expanding the recess in which freezing occurs. A reduction in strength below the initial value is to be expected and further cycle of freezing and thawing have a further marked effect. By using some experimental parameters like nuclear magnetic resonance variation (NMR), enthalpy-temperature (or heat capacity) variation, we can resolve between the various water states and their effect on concrete properties during cooling through the freezing transition temperature range. The main objective of this paper is to describe the principal type of water responsible for the reduction in strength and structural damage (frost damage) of concrete following repeated freeze –thaw cycles. Some experimental work was carried out at the institute of cryogenics to determine what happens to water in concrete during the freezing transition.
Abstract: COPD is characterized by loss of elastic fibers from
small airways and alveolar walls, with the decrease in elastin
increasing with disease severity. It is unclear why there is a lack of
repair of elastic fibers. We have examined fibroblasts cultured from
lung tissue from normal and COPD subjects to determine if the
secretory profile explains lack of tissue repair. In this study,
fibroblasts were cultured from lung parenchyma of bronchial
carcinoma patients with varying degrees of COPD; controls
(non-COPD, n=5), mild COPD (GOLD 1, n=5) and moderate-severe
COPD (GOLD 2-3, n=12). Measurements were made of proliferation,
senescence-associated beta-galactosidase-1, mRNA expression of
IL-6, IL-8, MMP-1, tropoelastin and versican, and protein levels for
IL-6, IL-8, PGE2, tropoelastin, insoluble elastin, and versican. It was
found that GOLD 2-3 fibroblasts proliferated more slowly (p
Abstract: In this article we explore how computer assisted exercises may allow for bridging the traditional gap between theory and practice in professional education. To educate officers able to master the complexity of the battlefield the Norwegian Military Academy needs to develop a learning environment that allows for creating viable connections between the educational environment and the field of practice. In response to this challenge we explore the conditions necessary to make computer assisted training systems (CATS) a useful tool to create structural similarities between an educational context and the field of military practice. Although, CATS may facilitate work procedures close to real life situations, this case do demonstrate how professional competence also must build on viable learning theories and environments. This paper explores the conditions that allow for using simulators to facilitate professional competence from within an educational setting. We develop a generic didactic model that ascribes learning to participation in iterative cycles of action and reflection. The development of this model is motivated by the need to develop an interdisciplinary professional education rooted in the pattern of military practice.
Abstract: Impact is one of very important subjects which always have been considered in mechanical science. Nature of impact is such that which makes its control a hard task. Therefore it is required to present the transfer of impact to other vulnerable part of a structure, when it is necessary, one of the best method of absorbing energy of impact, is by using Thin-walled tubes these tubes collapses under impact and with absorption of energy, it prevents the damage to other parts.Purpose of recent study is to survey the deformation and energy absorption of tubes with different type of cross section (rectangular or square) and with similar volumes, height, mean cross section thickness, and material under loading with different speeds. Lateral loading of tubes are quasi-static type and beside as numerical analysis, also experimental experiences has been performed to evaluate the accuracy of the results. Results from the surveys is indicates that in a same conditions which mentioned above, samples with square cross section ,absorb more energy compare to rectangular cross section, and also by increscent in speed of loading, energy absorption would be more.
Abstract: Abdominal aortic aneurysms rupture (AAAs) is one of the main causes of death in the world. This is a very complex phenomenon that usually occurs “without previous warning". Currently, criteria to assess the aneurysm rupture risk (peak diameter and growth rate) can not be considered as reliable indicators. In a first approach, the main geometric parameters of aneurysms have been linked into five biomechanical factors. These are combined to obtain a dimensionless rupture risk index, RI(t), which has been validated preliminarily with a clinical case and others from literature. This quantitative indicator is easy to understand, it allows estimating the aneurysms rupture risks and it is expected to be able to identify the one in aneurysm whose peak diameter is less than the threshold value. Based on initial results, a broader study has begun with twelve patients from the Clinic Hospital of Valladolid-Spain, which are submitted to periodic follow-up examinations.
Abstract: Mycotoxin (aflatoxins) contamination of peanuts is a
great concern for human health. A total of 72 samples of unripe,
roasted, and salty peanuts were collected randomly from Pothohar
plateau of Pakistan for the assessment of aflatoxin. Samples were
dried, ground and extracted by acetonitrile (84%). The filtered
extracts were cleaned up by MycoSep-226 and analyzed by high
performance liquid chromatography with flourescence detector.
Quantification limit of Aflatoxin was 1 μg/kg and 70% Recovery was
observed in spiked samples in the range 1–10 μg/kg. The screening
of mycotoxins indicated that aflatoxins were present in most of the
samples being detected in 82%, in concentrations from 14.25 μg/kg
to 98.80 μg/kg. Optimal conditions for mycotoxin production and
fungal growth are frequently found in the crop fields as well as in
store houses. Human exposure of such toxin can be controlled by
pointed out such awareness and implemented the regulations.
Abstract: In the present study, the effect of ferrous sulfate concentration and total solids on bioleaching of heavy metals from sewage sludge has been examined using indigenous iron-oxidizing microorganisms. The experiments on effects of ferrous sulfate concentrations on bioleaching were carried out using ferrous sulfate of different concentrations (5-20 g L-1) to optimize the concentration of ferrous sulfate for maximum bioleaching. A rapid change in the pH and ORP took place in first 2 days followed by a slow change till 16th day in all the sludge samples. A 10 g L-1 ferrous sulfate concentration was found to be sufficient in metal bioleaching in the following order: Zn: 69%>Cu: 52%>Cr: 46%>Ni: 45. Further, bioleaching using 10 g/L ferrous sulfate was found to be efficient up to 20 g L-1 sludge solids concentration. The results of the present study strongly indicate that using 10 g L-1 ferrous sulfate indigenous iron-oxidizing microorganisms can bring down pH to a value needed for significant metal solubilization.
Abstract: Fundamental sensor-motor couplings form the backbone
of most mobile robot control tasks, and often need to be implemented
fast, efficiently and nevertheless reliably. Machine learning
techniques are therefore often used to obtain the desired sensor-motor
competences.
In this paper we present an alternative to established machine
learning methods such as artificial neural networks, that is very fast,
easy to implement, and has the distinct advantage that it generates
transparent, analysable sensor-motor couplings: system identification
through nonlinear polynomial mapping.
This work, which is part of the RobotMODIC project at the
universities of Essex and Sheffield, aims to develop a theoretical understanding
of the interaction between the robot and its environment.
One of the purposes of this research is to enable the principled design
of robot control programs.
As a first step towards this aim we model the behaviour of the
robot, as this emerges from its interaction with the environment, with
the NARMAX modelling method (Nonlinear, Auto-Regressive, Moving
Average models with eXogenous inputs). This method produces
explicit polynomial functions that can be subsequently analysed using
established mathematical methods.
In this paper we demonstrate the fidelity of the obtained NARMAX
models in the challenging task of robot route learning; we present a
set of experiments in which a Magellan Pro mobile robot was taught
to follow four different routes, always using the same mechanism to
obtain the required control law.
Abstract: Concerning the measurement of friction properties of
textiles and fabrics using Kawabata Evaluation System (KES), whose
output is constrained to the surface friction factor of fabric, and no
other data would be generated; this research has been conducted to
gain information about surface roughness regarding its surface
friction factor. To assess roughness properties of light nonwovens, a
3-dimensional model of a surface has been simulated with regular
sinuous waves through it as an ideal surface. A new factor was
defined, namely Surface Roughness Factor, through comparing
roughness properties of simulated surface and real specimens. The
relation between the proposed factor and friction factor of specimens
has been analyzed by regression, and results showed a meaningful
correlation between them. It can be inferred that the new presented
factor can be used as an acceptable criterion for evaluating the
roughness properties of light nonwoven fabrics.
Abstract: This paper proposes and analyses the wireless
telecommunication system with multiple antennas to the emission
and reception MIMO (multiple input multiple output) with space
diversity in a OFDM context. In particular it analyses the
performance of a DTT (Digital Terrestrial Television) broadcasting
system that includes MIMO-OFDM techniques. Different
propagation channel models and configurations are considered for
each diversity scheme. This study has been carried out in the context
of development of the next generation DVB-T/H and WRAN.
Abstract: Oxidative stress is considered to be the cause for onset
and the progression of type 2 diabetes mellitus (T2DM) and
complications including neuropathy. It is a deleterious process that
can be an important mediator of damage to cell structures: protein,
lipids and DNA. Data suggest that in patients with diabetes and
diabetic neuropathy DNA repair is impaired, which prevents effective
removal of lesions. Objective: The aim of our study was to evaluate
the association of the hOGG1 (326 Ser/Cys) and XRCC1 (194
Arg/Trp, 399 Arg/Gln) gene polymorphisms whose protein is
involved in the BER pathway with DNA repair efficiency in patients
with diabetes type 2 and diabetic neuropathy compared to the healthy
subjects. Genotypes were determined by PCR-RFLP analysis in 385
subjects, including 117 with type 2 diabetes, 56 with diabetic
neuropathy and 212 with normal glucose metabolism. The
polymorphisms studied include codon 326 of hOGG1 and 194, 399
of XRCC1 in the base excision repair (BER) genes. Comet assay was
carried out using peripheral blood lymphocytes from the patients and
controls. This test enabled the evaluation of DNA damage in cells
exposed to hydrogen peroxide alone and in the combination with the
endonuclease III (Nth). The results of the analysis of polymorphism
were statistically examination by calculating the odds ratio (OR) and
their 95% confidence intervals (95% CI) using the ¤ç2-tests. Our data
indicate that patients with diabetes mellitus type 2 (including those
with neuropathy) had higher frequencies of the XRCC1 399Arg/Gln
polymorphism in homozygote (GG) (OR: 1.85 [95% CI: 1.07-3.22],
P=0.3) and also increased frequency of 399Gln (G) allele (OR: 1.38
[95% CI: 1.03-1.83], P=0.3). No relation to other polymorphisms
with increased risk of diabetes or diabetic neuropathy. In T2DM
patients complicated by neuropathy, there was less efficient repair of
oxidative DNA damage induced by hydrogen peroxide in both the
presence and absence of the Nth enzyme. The results of our study
suggest that the XRCC1 399 Arg/Gln polymorphism is a significant
risk factor of T2DM in Polish population. Obtained data suggest a
decreased efficiency of DNA repair in cells from patients with
diabetes and neuropathy may be associated with oxidative stress.
Additionally, patients with neuropathy are characterized by even
greater sensitivity to oxidative damage than patients with diabetes,
which suggests participation of free radicals in the pathogenesis of
neuropathy.
Abstract: This paper describes a proposed support system which
enables applications designers to effectively create VR applications
using multiple haptic APIs. When the VR designers create
applications, it is often difficult to handle and understand many
parameters and functions that have to be set in the application program
using documentation manuals only. This complication may disrupt
creative imagination and result in inefficient coding. So, we proposed
the support application which improved the efficiency of VR
applications development and provided the interactive components of
confirmation of operations with haptic sense previously.
In this paper, we describe improvements of our former proposed
support application, which was applicable to multiple APIs and haptic
devices, and evaluate the new application by having participants
complete VR program. Results from a preliminary experiment suggest
that our application facilitates creation of VR applications.
Abstract: The objective of this research was to identify the
vegetation-soil relationships in Nodushan arid rangelands of Yazd. 5
sites were selected for measuring the cover of plant species and soil
attributes. Soil samples were taken in 0-10 and 10-80 cm layers. The
species studied were Salsola tomentosa, Salsola arbuscula, Peganum
harmala, Zygophylum eurypterum and Eurotia ceratoides. Canonical
correspondence analysis (CCA) was used to analyze the data. Based
on the CCA results, 74.9 % of vegetation-soil variation was explained
by axis 1-3. Axis 1, 2 and 3 accounted for 27.2%, 24.9 % and 22.8%
of variance respectively. Correlation between axis 1, 2, 3 and speciesedaphic
variables were 0.995, 0.989, 0.981 respectively. Soil texture,
lime, salinity and organic matter significantly influenced the
distribution of these plant species. Determination of soil-vegetation
relationships will be useful for managing and improving rangelands
in arid and semi arid environments.
Abstract: The objective from this paper is to design a solar
thermal engine for space vehicles orbital control and electricity
generation. A computational model is developed for the prediction of
the solar thermal engine performance for different design parameters and conditions in order to enhance the engine efficiency. The engine is divided into two main subsystems. First, the concentrator dish
which receives solar energy from the sun and reflects them to the
cavity receiver. The second one is the cavity receiver which receives
the heat flux reflected from the concentrator and transfers heat to the
fluid passing over. Other subsystems depend on the application required from the engine. For thrust application, a nozzle is
introduced to the system for the fluid to expand and produce thrust.
Hydrogen is preferred as a working fluid in the thruster application.
Results model developed is used to determine the thrust for a
concentrator dish 4 meters in diameter (provides 10 kW of energy),
focusing solar energy to a 10 cm aperture diameter cavity receiver.
The cavity receiver outer length is 50 cm and the internal cavity is 47
cm in length. The suggested design material of the internal cavity is
tungsten to withstand high temperature. The thermal model and
analysis shows that the hydrogen temperature at the plenum reaches
2000oK after about 250 seconds for hot start operation for a flow rate
of 0.1 g/sec.Using solar thermal engine as an electricity generation
device on earth is also discussed. In this case a compressor and
turbine are used to convert the heat gained by the working fluid (air)
into mechanical power. This mechanical power can be converted into
electrical power by using a generator.
Abstract: This study shows palynomorphological description of
pollen grains of Lamium garganicum, species of the family Labiatae.
Fresh material of this plant is taken in Mount Llogara, in Albania. By
comparison made between palinomorphological characteristics of
pollen grains of Lamium garganicum with those of Lamium
maculatum and Lamium purpureum, showed that granules have
similarities in the number of furrows. The pollen grains of Lamium
garganicum were larger in length and width than those of Lamium
maculatum and almost equal with those of Lamium purpureum.
Furrows are longer than those of pollen grains in Lamium maculatum
and shorter than those of Lamium purpureum. The layer of exine of
Lamium garganicum was thinner than that of two others. The
sculpture of exine was fine reticulate, where reticulas were uniform
whereas in Lamium purpureum was verrucate, with small verrucae; in
Lamium maculatum was reticulate.
Abstract: In this work, the primary compressive strength
components of human femur trabecular bone are qualitatively
assessed using image processing and wavelet analysis. The Primary
Compressive (PC) component in planar radiographic femur trabecular
images (N=50) is delineated by semi-automatic image processing
procedure. Auto threshold binarization algorithm is employed to
recognize the presence of mineralization in the digitized images. The
qualitative parameters such as apparent mineralization and total area
associated with the PC region are derived for normal and abnormal
images.The two-dimensional discrete wavelet transforms are utilized
to obtain appropriate features that quantify texture changes in medical
images .The normal and abnormal samples of the human femur are
comprehensively analyzed using Harr wavelet.The six statistical
parameters such as mean, median, mode, standard deviation, mean
absolute deviation and median absolute deviation are derived at level
4 decomposition for both approximation and horizontal wavelet
coefficients. The correlation coefficient of various wavelet derived
parameters with normal and abnormal for both approximated and
horizontal coefficients are estimated. It is seen that in almost all cases
the abnormal show higher degree of correlation than normals. Further
the parameters derived from approximation coefficient show more
correlation than those derived from the horizontal coefficients. The
parameters mean and median computed at the output of level 4 Harr
wavelet channel was found to be a useful predictor to delineate the
normal and the abnormal groups.
Abstract: The clinical usefulness of heart rate variability is
limited to the range of Holter monitoring software available. These
software algorithms require a normal sinus rhythm to accurately
acquire heart rate variability (HRV) measures in the frequency
domain. Premature ventricular contractions (PVC) or more
commonly referred to as ectopic beats, frequent in heart failure,
hinder this analysis and introduce ambiguity. This investigation
demonstrates an algorithm to automatically detect ectopic beats by
analyzing discrete wavelet transform coefficients. Two techniques
for filtering and replacing the ectopic beats from the RR signal are
compared. One technique applies wavelet hard thresholding
techniques and another applies linear interpolation to replace ectopic
cycles. The results demonstrate through simulation, and signals
acquired from a 24hr ambulatory recorder, that these techniques can
accurately detect PVC-s and remove the noise and leakage effects
produced by ectopic cycles retaining smooth spectra with the
minimum of error.