Abstract: Nowadays, the rapid development of CAD systems’
programming environments results in the creation of multiple
downstream applications, which are developed and becoming
increasingly available. CAD based manufacturing simulations is
gradually following the same trend. Drilling is the most popular holemaking
process used in a variety of industries. A specially built piece
of software that deals with the drilling kinematics is presented. The
cutting forces are calculated based on the tool geometry, the cutting
conditions and the tool/work-piece materials. The results are verified
by experimental work. Finally, the response surface methodology
(RSM) is applied and mathematical models of the total thrust force
and the thrust force developed because of the main cutting edges are
proposed.
Abstract: Metal thin-walled members have been widely used in
building industry. Usually they are utilized as purlins, girts or ceiling
beams. Due to slenderness of thin-walled cross-sections these
structural members are prone to stability problems (e.g. flexural
buckling, lateral torsional buckling). If buckling is not
constructionally prevented their resistance is limited by buckling
strength. In practice planar members of roof or wall cladding can be
attached to thin-walled members. These elements reduce
displacement of thin-walled members and therefore increase their
buckling strength. If this effect is taken into static assessment more
economical sections of thin-walled members might be utilized and
certain savings of material might be achieved. This paper focuses on
problem of determination of critical load of steel thin-walled beams
with lateral continuous restraint which is crucial for lateral torsional
buckling assessment.
Abstract: Aluminium matrix composites with alumina
reinforcements give superior mechanical & physical properties. Their
applications in several fields like automobile, aerospace, defense,
sports, electronics, bio-medical and other industrial purposes are
becoming essential for the last several decades. In the present work,
fabrication of hybrid composite was done by Stir casting technique
using Al 6061 as a matrix with alumina and silicon carbide (SiC) as
reinforcement materials. The weight percentage of alumina is varied
from 2 to 4% and the silicon carbide weight percentage is maintained
constant at 2%. Hardness and wear tests are performed in the as cast
and heat treated conditions. Age hardening treatment was performed
on the specimen with solutionizing at 550°C, aging at two
temperatures (150 and 200°C) for different time durations. Hardness
distribution curves are drawn and peak hardness values are recorded.
Hardness increase was very sensitive with respect to the decrease in
aging temperature. There was an improvement in wear resistance of
the peak aged material when aged at lower temperature. Also
increase in weight percent of alumina, increases wear resistance at
lower temperature but opposite behavior was seen when aged at
higher temperature.
Abstract: This paper addresses a cutting edge method of
business demand forecasting, based on an empirical probability
function when the historical behavior of the data is random.
Additionally, it presents error determination based on the numerical
method technique ‘propagation of errors.’ The methodology was
conducted characterization and process diagnostics demand planning
as part of the production management, then new ways to predict its
value through techniques of probability and to calculate their mistake
investigated, it was tools used numerical methods. All this based on
the behavior of the data. This analysis was determined considering
the specific business circumstances of a company in the sector of
communications, located in the city of Bogota, Colombia. In
conclusion, using this application it was possible to obtain the
adequate stock of the products required by the company to provide its
services, helping the company reduce its service time, increase the
client satisfaction rate, reduce stock which has not been in rotation
for a long time, code its inventory, and plan reorder points for the
replenishment of stock.
Abstract: The present study was aimed to examine the structure
of children’s adaptation during school transition and to identify a
commonality and dissimilarity at the elementary and junior high
school. 1,983 students in the 6th grade and 2,051 students in the 7th
grade were extracted by stratified two-stage random sampling and
completed the ASSESS that evaluated the school adaptation from the
view point of ‘general satisfaction’, ‘teachers’ support’, ‘friends’
support’, ‘anti-bullying relationship’, ‘prosocial skills’, and ‘academic
adaptation’. The 7th graders tend to be worse adaptation than the 6th
graders. A structural equation modeling showed the goodness of fit for
each grades. Both models were very similar but the 7th graders’ model
showed a lower coefficient at the pass from ‘teachers’ support’ to
‘friends’ support’. The role of ‘teachers’ support’ was decreased to
keep a good relation in junior high school. We also discussed how we
provide a continuous assistance for prevention of the 7th graders’ gap.
Abstract: In order to address construction project requirements
and specifications, scholars and practitioners need to establish
taxonomy according to a scheme that best fits their need. While
existing characterization methods are continuously being improved,
new ones are devised to cover project properties which have not been
previously addressed. One such method, the Project Definition Rating
Index (PDRI), has received limited consideration strictly as a
classification scheme. Developed by the Construction Industry
Institute (CII) in 1996, the PDRI has been refined over the last two
decades as a method for evaluating a project's scope definition
completeness during front-end planning (FEP). The main
contribution of this study is a review of practical project classification
methods, and a discussion of how PDRI can be used to classify
projects based on their readiness in the FEP phase. The proposed
model has been applied to 59 construction projects in Ontario, and
the results are discussed.
Abstract: Methicillin/multiple-resistant Staphylococcus aureus
(MRSA) are infectious bacteria that are resistant to common
antibiotics. A previous in silico study in our group has identified a
hypothetical protein SAV1226 as one of the potential drug targets. In
this study, we reported the bioinformatics characterization, as well as
cloning, expression, purification and kinetic assays of hypothetical
protein SAV1226 from methicillin/vancomycin-resistant
Staphylococcus aureus Mu50 strain. MALDI-TOF/MS analysis
revealed a low degree of structural similarity with known proteins.
Kinetic assays demonstrated that hypothetical protein SAV1226 is
neither a domain of an ATP dependent dihydroxyacetone kinase nor
of a phosphotransferase system (PTS) dihydroxyacetone kinase,
suggesting that the function of hypothetical protein SAV1226 might
be misannotated on public databases such as UniProt and
InterProScan 5.
Abstract: This study is aiming at establishing the relationship
between the optical signal of flame and an equivalent ratio of flame. In
this experiment, flame optical signal in a furnace is measured using
photodiode. The combustion system is composed of metal fiber burner
and vertical furnace, and flame chemiluminescence is measured at
various experimental conditions. In this study, the flame
chemiluminescence of laminar premixed flame is measured using
commercially available photodiode. It is experimentally investigated
the relationship between equivalent ratio and photodiode signal. In
addition, the strategy of combustion control method is proposed using
the optical signal and fuel pressure.
The results showed that certain relationship between optical data of
photodiode and equivalence ratio exists, and this leads to the
successful application of this system for instantaneous measurement of
equivalence ration of the combustion system.
Abstract: When neck pain is associated with pain, numbness, or
weakness in the arm, shoulder, or hand, further investigation is
needed as these are symptoms indicating pressure on one or more
nerve roots. Evaluation necessitates a neurologic examination and
imaging using an MRI/CT scan. A degenerating disc loses some
thickness and is less flexible, causing inter-vertebrae space to narrow.
A radiologist diagnoses an Intervertebral Disc Degeneration (IDD) by
localizing every inter-vertebral disc and identifying the pathology in
a disc based on its geometry and appearance. Accurate localizing is
necessary to diagnose IDD pathology. But, the underlying image
signal is ambiguous: a disc’s intensity overlaps the spinal nerve
fibres. Even the structure changes from case to case, with possible
spinal column bending (scoliosis). The inter-vertebral disc
pathology’s quantitative assessment needs accurate localization of the
cervical region discs. In this work, the efficacy of multilevel set
segmentation model, to segment cervical discs is investigated. The
segmented images are annotated using a simple distance matrix.
Abstract: Bringing forth a survey on recent higher order spline
techniques for solving boundary value problems in ordinary
differential equations. Here we have discussed the summary of the
articles since 2000 till date based on higher order splines like Septic,
Octic, Nonic, Tenth, Eleventh, Twelfth and Thirteenth Degree
splines. Comparisons of methods with own critical comments as
remarks have been included.
Abstract: Steady three-dimensional and two free surface waves
generated by moving bodies are presented, the flow problem to be
simulated is rich in complexity and poses many modeling challenges
because of the existence of breaking waves around the ship hull, and
because of the interaction of the two-phase flow with the turbulent
boundary layer. The results of several simulations are reported. The
first study was performed for NACA0012 of hydrofoil with different
meshes, this section is analyzed at h/c= 1, 0345 for 2D. In the second
simulation a mathematically defined Wigley hull form is used to
investigate the application of a commercial CFD code in prediction of
the total resistance and its components from tangential and normal
forces on the hull wetted surface. The computed resistance and wave
profiles are used to estimate the coefficient of the total resistance for
Wigley hull advancing in calm water under steady conditions. The
commercial CFD software FLUENT version 12 is used for the
computations in the present study. The calculated grid is established
using the code computer GAMBIT 2.3.26. The shear stress k-ωSST
model is used for turbulence modeling and the volume of fluid
technique is employed to simulate the free-surface motion. The
second order upwind scheme is used for discretizing the convection
terms in the momentum transport equations, the Modified HRIC
scheme for VOF discretization. The results obtained compare well
with the experimental data.
Abstract: A compound parabolic concentrator (CPC) is a wellknown
non-imaging concentrator that will concentrate the solar
radiation onto receiver (PV cell). One of disadvantage of CPC is has
tall and narrow height compared to its diameter entry aperture area.
Therefore, for economic reason, a truncation had been done by
removed from the top of the full height CPC. This also will lead to
the decreases of concentration ratio but it will be negligible. In this
paper, the flux distribution of untruncated and truncated 2-D hollow
compound parabolic trough concentrator (hCPTC) design is
presented. The untruncated design has initial height H=193.4mm
with concentration ratio C_(2-D)=4. This paper presents the optical
simulation of compound parabolic trough concentrator using raytracing
software TracePro. Results showed that, after the truncation,
the height of CPC reduced 45% from initial height with the
geometrical concentration ratio only decrease 10%. Thus, the cost of
reflector and material dielectric usage can be saved especially at
manufacturing site.
Abstract: The Economic Lot Scheduling Problem (ELSP) is a
valuable mathematical model that can support decision-makers to
make scheduling decisions. The basic period approach is effective for
solving the ELSP. The assumption for applying the basic period
approach is that a product must use its maximum production rate to be
produced. However, a product can lower its production rate to reduce
the average total cost when a facility has extra idle time. The past
researches discussed how a product adjusts its production rate under
the common cycle approach. To the best of our knowledge, no studies
have addressed how a product lowers its production rate under the
basic period approach. This research is the first paper to discuss this
topic. The research develops a simple fixed rate approach that adjusts
the production rate of a product under the basic period approach to
solve the ELSP. Our numerical example shows our approach can find a
better solution than the traditional basic period approach. Our
mathematical model that applies the fixed rate approach under the
basic period approach can serve as a reference for other related
researches.
Abstract: To ensure targeting of apoferritin nanocarrier with
encapsulated doxorubicin drug, we used a peptide linker based on a
protein G with N-terminus affinity towards Fc region of antibodies.
To connect the peptide to the surface of apoferritin, the C-terminus of
peptide was made of cysteine with affinity to gold. The surface of
apoferritin with encapsulated doxorubicin (APODOX) was coated
either with gold nanoparticles (APODOX-Nano) or gold(III) chloride
hydrate reduced with sodium borohydride (APODOX-HAu). The
reduction with sodium borohydride caused a loss of doxorubicin
fluorescent properties and probably accompanied with the loss of its
biological activity. Fluorescent properties of APODOX-Nano were
similar to the unmodified APODOX; therefore it was more suited for
the intended use. To evaluate the specificity of apoferritin modified
with antibodies, ELISA-like method was used with the surface of
microtitration plate wells coated by the antigen (goat anti-human IgG
antibodies). To these wells, the nanocarrier was applied. APODOX
without the modification showed 5× lower affinity to the antigen than
APODOX-Nano modified gold and targeting antibodies (human IgG
antibodies).
Abstract: The novel 3D SnO cabbages self-assembled by
nanosheets were successfully synthesized via template-free
hydrothermal growth method under facile conditions. The XRD
results manifest that the as-prepared SnO is tetragonal phase. The
TEM and HRTEM results show that the cabbage nanosheets are
polycrystalline structure consisted of considerable single-crystalline
nanoparticles. Two typical Raman modes A1g=210 and Eg=112 cm-1
of SnO are observed by Raman spectroscopy. Moreover, galvanostatic
cycling tests has been performed using the SnO cabbages as anode
material of lithium ion battery and the electrochemical results suggest
that the synthesized SnO cabbage structures are a promising anode
material for lithium ion batteries.
Abstract: Current research is targeting new molecular
mechanisms that underlie non-alcoholic fatty liver disease (NAFLD)
and associated metabolic disorders like non-alcoholic steatohepatitis
(NASH). Forty New Zealand White rabbits have been used and fed a
high protein (HP) and energy diet based on grains and containing
11.76 MJ/kg. Boron added to 3 experimental groups’ drinking waters
(30 mg boron/L) as boron compounds. Biochemical analysis
including boron levels, and nuclear magnetic resonance (NMR) based
metabolomics evaluation, and mRNA expression of peroxisome
proliferator-activated receptor (PPAR) family was performed. LDLcholesterol
concentrations alone were decreased in all the
experimental groups. Boron levels in serum and feces were increased.
Content of acetate was in about 2x higher for anhydrous borax group,
at least 3x higher for boric acid group. PPARα mRNA expression
was significantly decreased in boric acid group. Anhydrous borax
attenuated mRNA levels of PPARγ, which was further suppressed by
boric acid. Boron supplementation decreased the degenerative
alterations in hepatocytes. Except borax group other boron groups did
not have a pronounced change in tubular epithels of kidney. In
conclusion, high protein and energy diet leads hepatocytes’
degenerative changes which can be prevented by boron
supplementation. Boric acid seems to be more effective in this
situation.
Abstract: Total Quality Management (TQM) is a managerial
approach that improves the competitiveness of the industry,
meanwhile Information technology (IT) was introduced with TQM
for handling the technical issues which is supported by quality
experts for fulfilling the customers’ requirement. Present paper aims
to utilise AHP (Analytic Hierarchy Process) methodology to
priorities and rank the hierarchy levels of TQM enablers and IT
resource together for its successful implementation in the Information
and Communication Technology (ICT) industry. A total of 17 TQM
enablers (nine) and IT resources (eight) were identified and
partitioned into 3 categories and were prioritised by AHP approach.
The finding indicates that the 17 sub-criteria can be grouped into
three main categories namely organizing, tools and techniques, and
culture and people. Further, out of 17 sub-criteria, three sub-criteria:
top management commitment and support, total employee
involvement, and continuous improvement got highest priority
whereas three sub-criteria such as structural equation modelling,
culture change, and customer satisfaction got lowest priority. The
result suggests a hierarchy model for ICT industry to prioritise the
enablers and resources as well as to improve the TQM and IT
performance in the ICT industry. This paper has some managerial
implication which suggests the managers of ICT industry to
implement TQM and IT together in their organizations to get
maximum benefits and how to utilize available resources. At the end,
conclusions, limitation, future scope of the study are presented.
Abstract: The system for analyzing and eliciting public
grievances serves its main purpose to receive and process all sorts of
complaints from the public and respond to users. Due to the more
number of complaint data becomes big data which is difficult to store
and process. The proposed system uses HDFS to store the big data
and uses MapReduce to process the big data. The concept of cache
was applied in the system to provide immediate response and timely
action using big data analytics. Cache enabled big data increases the
response time of the system. The unstructured data provided by the
users are efficiently handled through map reduce algorithm. The
processing of complaints takes place in the order of the hierarchy of
the authority. The drawbacks of the traditional database system used
in the existing system are set forth by our system by using Cache
enabled Hadoop Distributed File System. MapReduce framework
codes have the possible to leak the sensitive data through
computation process. We propose a system that add noise to the
output of the reduce phase to avoid signaling the presence of
sensitive data. If the complaints are not processed in the ample time,
then automatically it is forwarded to the higher authority. Hence it
ensures assurance in processing. A copy of the filed complaint is sent
as a digitally signed PDF document to the user mail id which serves
as a proof. The system report serves to be an essential data while
making important decisions based on legislation.
Abstract: Because blueberries are worldwide recognized as a
good source of beneficial components, their consumption has
increased in the past decades, and so have the scientific works about
their properties. Hence, this work was undertaken to evaluate the
effect of some production and conservation factors on the properties
of blueberries from cultivar Bluecrop. The physical and chemical
analyses were done according to established methodologies and then
all data was treated using software SPSS for assessment of the
possible differences among the factors investigated and/or the
correlations between the variables at study. The results showed that
location of production influenced some of the berries properties
(caliber, sugars, antioxidant activity, color and texture) and that the
age of the bushes was correlated with moisture, sugars and acidity, as
well as lightness. On the other hand, altitude of the farm only was
correlated to sugar content. With regards to conservation, it
influenced only anthocyanins content and DPPH antioxidant activity.
Finally, the type of extract and the order of extraction had a
pronounced influence on all the phenolic properties evaluated.
Abstract: In the past decade, the use of digital image correlation
(DIC) techniques has increased significantly in the area of
experimental mechanics, especially for materials behavior
characterization. This non-contact tool enables full field displacement
and strain measurements over a complete region of interest. The DIC
algorithm requires a random contrast pattern on the surface of the
specimen in order to perform properly. To create this pattern, the
specimen is usually first coated using a white matt paint. Next, a
black random speckle pattern is applied using any suitable method. If
the applied paint coating is too thick, its top surface may not be able
to exactly follow the deformation of the specimen, and consequently,
the strain measurement might be underestimated. In the present
article, a study of the influence of the paint thickness on the strain
underestimation is performed for different strain levels. The results
are then compared to typical paint coating thicknesses applied by
experienced DIC users. A slight strain underestimation was observed
for paint coatings thicker than about 30μm. On the other hand, this
value was found to be uncommonly high compared to coating
thicknesses applied by DIC users.