Abstract: Advanced head and neck cancers are aggressive
tumours, which require aggressive treatment. Treatment efficiency is
often hindered by cancer cell repopulation during radiotherapy,
which is due to various mechanisms triggered by the loss of tumour
cells and involves both stem and differentiated cells. The aim of the
current paper is to present in silico simulations of radiotherapy
schedules on a virtual head and neck tumour grown with biologically
realistic kinetic parameters. Using the linear quadratic formalism of
cell survival after radiotherapy, altered fractionation schedules
employing various treatment breaks for normal tissue recovery are
simulated and repopulation mechanism implemented in order to
evaluate the impact of various cancer cell contribution on tumour
behaviour during irradiation. The model has shown that the timing of
treatment breaks is an important factor influencing tumour control in
rapidly proliferating tissues such as squamous cell carcinomas of the
head and neck. Furthermore, not only stem cells but also
differentiated cells, via the mechanism of abortive division, can
contribute to malignant cell repopulation during treatment.
Abstract: Bio-composites derived from plant fiber and/or bioderived
polymer, are likely more ecofriendly and demonstrate
competitive performance with petroleum based composites. In this
research, the bio phenol-formaldehyde (bio-PF) was used as a matrix
and oil palm empty fruit bunch fiber (EFB) as reinforcement. The
matrix was synthesized via liquefaction and condensation to enhance
the combination of phenol and formaldehyde, during the process.
Then, the bio-PF was mixed with different percentage of EFB (5%,
10%, 15% and 20%) and molded at 180oC. The samples that viewed
under scanning electron microscopy (SEM) showed an excellent
wettability and interaction between EFB and matrix. Samples of 10%
EFB gave the optimum properties of impact and hardness meanwhile
sample 15% of EFB gave the highest reading of flexural modulus
(MOE) and flexural strength (MOR). For thermal stability analysis, it
was found that the weight loss and the activation energy (Ea) of the
bio-composites samples were decreased as the filler content
increased.
Abstract: This paper presents modeling of an Alternating
Current (AC) Photovoltaic (PV) module using Matlab/Simulink. The
proposed AC-PV module model is simple, realistic, and application
oriented. The model is derived on module level as compared to cell
level directly from the information provided by the manufacturer data
sheet. DC-PV module, MPPT control, BC, VSI and LC filter, all
were treated as a single unit. The model accounts for changes in
variations of both irradiance and temperature. The AC-PV module
proposed model is simulated and the results are compared with the
datasheet projected numbers to validate model’s accuracy and
effectiveness. Implementation and results demonstrate simplicity and
accuracy, as well as reliability of the model.
Abstract: The prepreg process among the CFRP (Carbon Fiber
Reinforced Plastic) forming methods is the short term of
‘Pre-impregnation’, which is widely used for aerospace composites
that require a high quality property such as a fiber-reinforced woven
fabric, in which an epoxy hardening resin is impregnated the reality.
However, that this process requires continuous researches and
developments for its commercialization because the delamination
characteristically develops between the layers when a great weight is
loaded from outside to supplement such demerit, three lamination
methods among the prepreg lamination methods of CFRP were
designed to minimize the delamination between the layers due to
external impacts. Further, the newly designed methods and the
existing lamination methods were analyzed through a mechanical
characteristic test, Interlaminar Shear Strength test. The Interlaminar
Shear Strength test result confirmed that the newly proposed three
lamination methods, i.e. the Roll, Half and Zigzag laminations,
presented more excellent strengths compared to the conventional Ply
lamination. The interlaminar shear strength in the roll method with
relatively dense fiber distribution was approximately 1.75% higher
than that in the existing ply lamination method, and in the half method,
it was approximately 0.78% higher.
Abstract: In this paper, the electromagnetic shielding
characteristics of an up-to-date typical carbon filler material, carbon
fiber used with a metal mesh were investigated. Carbon fiber
12k-prepregs, where carbon fibers were impregnated with epoxy, were
laminated with wire meshes, vacuum bag-molded and hardened to
manufacture hybrid-type specimens, with which an electromagnetic
shield test was performed in accordance with ASTM D4935-10,
through which was known as the most excellent reproducibility is
obtainable among electromagnetic shield tests. In addition, glass fiber
prepregs whose electromagnetic shielding effect were known as
insignificant were laminated and formed with wire meshes to verify
the validity of the electromagnetic shield effect of wire meshes in
order to confirm the electromagnetic shielding effect of metal meshes
corresponding existing carbon fiber 12k-prepregs. By grafting carbon
fibers, on which studies are being actively underway in the
environmental aspects and electromagnetic shielding effect, with
hybrid-type wire meshes that were analysed through the tests, in this
study, the applicability and possibility are proposed.
Abstract: Bacterial strains capable of degradation of malathion
from the domestic sewage were isolated by an enrichment culture
technique. Three bacterial strains were screened and identified as
Acinetobacter baumannii (AFA), Pseudomonas aeruginosa (PS1),
and Pseudomonas mendocina (PS2) based on morphological,
biochemical identification and 16S rRNA sequence analysis.
Acinetobacter baumannii AFA was the most efficient malathion
degrading bacterium, so used for further biodegradation study. AFA
was able to grow in mineral salt medium (MSM) supplemented with
malathion (100 mg/l) as a sole carbon source, and within 14 days,
84% of the initial dose was degraded by the isolate measured by high
performance liquid chromatography. Strain AFA could also degrade
other organophosphorus compounds including diazinon, chlorpyrifos
and fenitrothion. The effect of different culture conditions on the
degradation of malathion like inoculum density, other carbon or
nitrogen sources, temperature and shaking were examined.
Degradation of malathion and bacterial cell growth were accelerated
when culture media were supplemented with yeast extract, glucose
and citrate. The optimum conditions for malathion degradation by
strain AFA were; an inoculum density of 1.5x 10^12CFU/ml at 30°C
with shaking. A specific polymerase chain reaction primers were
designed manually using multiple sequence alignment of the
corresponding carboxylesterase enzymes of Acinetobacter species.
Sequencing result of amplified PCR product and phylogenetic
analysis showed low degree of homology with the other
carboxylesterase enzymes of Acinetobacter strains, so we suggested
that this enzyme is a novel esterase enzyme. Isolated bacterial strains
may have potential role for use in bioremediation of malathion
contaminated.
Abstract: Leukaemia is a blood cancer disease that contributes
to the increment of mortality rate in Malaysia each year. There are
two main categories for leukaemia, which are acute and chronic
leukaemia. The production and development of acute leukaemia cells
occurs rapidly and uncontrollable. Therefore, if the identification of
acute leukaemia cells could be done fast and effectively, proper
treatment and medicine could be delivered. Due to the requirement of
prompt and accurate diagnosis of leukaemia, the current study has
proposed unsupervised pixel segmentation based on clustering
algorithm in order to obtain a fully segmented abnormal white blood
cell (blast) in acute leukaemia image. In order to obtain the
segmented blast, the current study proposed three clustering
algorithms which are k-means, fuzzy c-means and moving k-means
algorithms have been applied on the saturation component image.
Then, median filter and seeded region growing area extraction
algorithms have been applied, to smooth the region of segmented
blast and to remove the large unwanted regions from the image,
respectively. Comparisons among the three clustering algorithms are
made in order to measure the performance of each clustering
algorithm on segmenting the blast area. Based on the good sensitivity
value that has been obtained, the results indicate that moving kmeans
clustering algorithm has successfully produced the fully
segmented blast region in acute leukaemia image. Hence, indicating
that the resultant images could be helpful to haematologists for
further analysis of acute leukaemia.
Abstract: Anthocyanins are natural pigments with effective UV
protection but their topical use could be limited due to their
physicochemical characteristics. An attempt to overcome such
limitations by complexation of 2 major anthocyanin-rich sources, C.
ternatea and Z. mays, has potentiated its use as topical antiinflammatory.
Cell studies indicate no cytotoxicity of the
anthocyanin complex (AC) up to 1 mg/ml tested in HaCaT and
human fore head fibroblasts by MTT. Croton oil-induced ear edema
in Wistar rats suggests an effective dose of 5 mg/cm2 of AC as a
topical anti-inflammatory in comparison to 0.5 mg/cm2 of
fluocinolone acetonide. Niosomal encapsulation of the AC
significantly prolonged the anti-inflammatory activity particularly at
8 h after topical application (p = 0.0001). The AC was not cytotoxic
and its anti-inflammatory and activity was dose-dependent and
prolonged by niosomal encapsulation. It has also shown to promote
collagen type 1 production in cell culture. Thus, AC could be a
potential candidate for topical anti-inflammatory agent from natural
resources.
Abstract: Liver disorders are one of the major problems of the
world. Despite its frequent occurrence, high morbidity and high
mortality, its medical management is currently inadequate. This study
was designed to evaluate the hepatoprotective effect of saponin
extract of the root of Garcinia kola on the integrity of the liver of
paracetamol induced wistar albino rats. Twenty five (25) male adult
wistar albino rats were divided into five (5) groups. Group I was the
Control group that received distilled water only, group II was the
negative control that received 2 g/kg of paracetamol on the 13th day,
and group III, IV and V were pre-treated with 100, 200 and
400mg/kg of the saponin extract before inducing the liver damage on
the 13th day with 2 g/kg of paracetamol. Twenty four (24) h after
administration, the rats were sacrificed and blood samples were
collected. The serum Alanine Transaminase (ALT), Aspartate
Transaminase (AST), Alkaline Phosphatase (ALP) activities,
Bilirubin and conjugated bilirubin, glucose and protein
concentrations were evaluated. The liver was fixed immediately in
Formalin and was processed and stained in Haematoxylin and Eosin
(H&E). Administration of saponin extract from the root of Garcinia
kola significantly decreased paracetamol induced elevated enzymes
in the test group. Also histological observations showed that saponin
extract of the root of Garcinia kola exhibited a significant liver
protection against the toxicant as evident by the cells trying to return
to normal. Saponin extract from the root of Garcinia kola indicated a
protection of structural integrity of the hepatocytic cell membrane
and regeneration of the damaged liver.
Abstract: The present study was carried out to evaluate the
effect of different levels of dietary seed and extract of Harmal
(Peganum harmala L.) on immunity of broiler chicks. A total of 350
one-day old broiler chicks (Ross 308) were randomly allocated to
five dietary treatments with four replicates pen of 14 birds each.
Dietary treatments consisted of control, 1 and 2 g/kg Harmal seed in
diet, 100 and 200 mg/L Harmal seed extract in water. Broilers
received dietary treatments from 1 to 42 d. Two birds from each pen
were randomly weighed and sacrificed at 42 d of age, the relative
weight of lymphoid organs (bursa of Fabercius and spleen) to live
weight were calculated. Antibody titers against Newcastle and
influenza viruses and sheep red blood cell were measured at 30 d of
age. Results showed that the relative weights of lymphoid organs
were not affected by dietary treatments. Furthermore, antibody titer
against Newcastle and influenza viruses as well as sheep red blood
cell antigen were significantly (P
Abstract: In this study a ternary system containing sodium
chloride as solute, water as primary solvent and ethanol as the
antisolvent was considered to investigate the application of artificial
neural network (ANN) in prediction of sodium solubility in the
mixture of water as the solvent and ethanol as the antisolvent. The
system was previously studied using by Extended UNIQUAC model
by the authors of this study. The comparison between the results of
the two models shows an excellent agreement between them
(R2=0.99), and also approves the capability of ANN to predict the
thermodynamic behavior of ternary electrolyte systems which are
difficult to model.
Abstract: Welfare may be considered to be a subjective
experience; it has a biological function that is related to the fitness
and survival of the animal accordingly, researches have suggested
that welfare is compromised when the animal's evolutionary fitness is
reduced. This study was carried out to explain the effect of some
managerial stressors as handling and restraint on behavioral patterns
and biochemical parameters of rats. A total of 24 (12 males & 12
females) Sprague-Dawley rats (12 months & 150-180g) were allotted
into 3 groups, handled group (4 male & 4 female), restrained group (4
male & 4 female) and control group (4 males & 4 females).
The obtained results revealed that time spent feeding, drinking,
movement and cage exploration frequencies increased significantly in
handled rats than other groups, while lying time and licking increased
significantly in restrained rats than handled and controls. Moreover,
social behavior decreased in both stressed groups than control.
Triglycerides were significantly increased in handled rats than
other groups, while total lipid, total protein and globulin significantly
increased in both treated groups than control. Corticosterone
increased in restrained and handled rats than control ones. Moreover,
there was an increment in packed cell volume significantly in
restrained rats than others. These deducted that if we want to study
the effect of stress on animal welfare it is necessary to study the
effect of such stressors on animal’s behavior and physiological
responses.
Abstract: Recently, increasing the quality of experience (QoE) is
an important issue. Since performance degradation at cell edge
extremely reduces the QoE, several techniques are defined at
LTE/LTE-A standard to remove inter-cell interference (ICI). However,
the conventional techniques have disadvantage because there is a
trade-off between resource allocation and reliable communication.
The proposed scheme reduces the ICI more efficiently by using
channel state information (CSI) smartly. It is shown that the proposed
scheme can reduce the ICI with fewer resources.
Abstract: Replacement of plastics used in the food industry
seems to be a serious issue to overcome mainly the environmental
problems in recent years. This study investigates the hydrophilicity
and permeability properties of starch biopolymer which ethylene
vinyl alcohol (EVOH) (0-10%) and nanocrystalline cellulose (NCC)
(1-15%) were used to enhance its properties. Starch -EVOH
nanocomposites were prepared by casting method in different
formulations. NCC production by acid hydrolysis was confirmed by
scanning electron microscopy. Solubility, water vapor permeability,
water vapor transmission rate and moisture absorbance were
measured on each of the nanocomposites. The results were analyzed
by SAS software. The lowest moisture absorbance was measured in
pure starch nanocomposite containing 8% NCC. The lowest
permeability to water vapor belongs to starch nanocomposite
containing 8% NCC and the sample containing 7.8% EVOH and 13%
NCC. Also the lowest solubility was observed in the composite
contains the highest amount of EVOH. Applied Process resulted in
production of bio films which have good resistance to water vapor
permeability and solubility in water. The use of NCC and EVOH
leads to reduced moisture absorbance property of the biofilms.
Abstract: In the scope of application of technical textiles, Non-
Crimp Fabrics are increasingly used. In general, NCF exhibit
excellent load bearing properties, but caused by the manufacturing
process, there are some remaining disadvantages which have to be
reduced. Regarding to this, a novel technique of processing NCF was
developed substituting the binding-thread by an adhesive. This stitchfree
method requires new manufacturing concept as well as new basic
methods to prove adhesion of glue at fibres and textiles. To improve
adhesion properties and the wettability of carbon-fibres by the
adhesive, oxy-fluorination was used. The modification of carbonfibres
by oxy-fluorination was investigated via scanning electron
microscope, X-ray photoelectron spectroscopy and single fibre
tensiometry. Special tensile tests were developed to determine the
maximum force required for detachment.
Abstract: This paper impart the design and testing of
Nanotechnology based sequential circuits using multiplexer
conservative QCA (MX-CQCA) logic gates, which is easily testable
using only two vectors. This method has great prospective in the
design of sequential circuits based on reversible conservative logic
gates and also smashes the sequential circuits implemented in
traditional gates in terms of testability. Reversible circuits are similar
to usual logic circuits except that they are built from reversible gates.
Designs of multiplexer conservative QCA logic based two vectors
testable double edge triggered (DET) sequential circuits in VHDL
language are also accessible here; it will also diminish intricacy in
testing side. Also other types of sequential circuits such as D, SR, JK
latches are designed using this MX-CQCA logic gate. The objective
behind the proposed design methodologies is to amalgamate
arithmetic and logic functional units optimizing key metrics such as
garbage outputs, delay, area and power. The projected MX-CQCA
gate outshines other reversible gates in terms of the intricacy, delay.
Abstract: In this paper, extract of papaya leaves are used as a
natural dye and combined by variations of solvent concentration
applied on DSSC (Dye-Sensitized Solar Cell). Indonesian geographic
located on the equator line occasions the magnitude of the potential
to develop organic solar cells made from extracts of chlorophyll as a
substitute for inorganic materials or synthetic dye on DSSC material.
Dye serves as absorbing photons which are then converted into
electrical energy. A conductive coated glass layer called TCO
(Transparent Conductive Oxide) is used as a substrate of electrode.
TiO2 nanoparticles as binding dye molecules, redox couple iodide/
tri-iodide as the electrolyte and carbon as the counter electrode in the
DSSC are used. TiO2 nanoparticles, organic dyes, electrolytes, and
counter electrode are arranged and combined with the layered
structure of the photo-catalyst absorption layer. Dye absorption
measurements using a spectrophotometer at 400-800 nm light
spectrum produces a total amount of chlorophyll 80.076 mg/l. The
test cell at 7 watt LED light with 5000 lux luminescence was
obtained Voc and Isc of 235.5 mV and 14 μA, respectively.
Abstract: Nowadays, the successful implementation of ICTs is
vital for almost any kind of organization. Good governance and ICT
management are essential for delivering value, managing
technological risks, managing resources and performance
measurement. In addition, outsourcing is a strategic IT service
solution which complements IT services provided internally in
organizations. This paper proposes the measurement tools of a new
holistic maturity model based on standards ISO/IEC 20000 and
ISO/IEC 38500, and the frameworks and best practices of ITIL and
COBIT, with a specific focus on IT outsourcing. These measurement
tools allow independent validation and practical application in the
field of higher education, using a questionnaire, metrics tables, and
continuous improvement plan tables as part of the measurement
process. Guidelines and standards are proposed in the model for
facilitating adaptation to universities and achieving excellence in the
outsourcing of IT services.
Abstract: In this paper, we present a robust algorithm to recognize extracted text from grocery product images captured by mobile phone cameras. Recognition of such text is challenging since text in grocery product images varies in its size, orientation,
style, illumination, and can suffer from perspective distortion.
Pre-processing is performed to make the characters scale and
rotation invariant. Since text degradations can not be appropriately
defined using well-known geometric transformations such
as translation, rotation, affine transformation and shearing, we
use the whole character black pixels as our feature vector.
Classification is performed with minimum distance classifier
using the maximum likelihood criterion, which delivers very
promising Character Recognition Rate (CRR) of 89%. We
achieve considerably higher Word Recognition Rate (WRR) of
99% when using lower level linguistic knowledge about product
words during the recognition process.
Abstract: Femtocells are regarded as a milestone for next
generation cellular networks. As femtocells are deployed in an
unplanned manner, there is a chance of assigning same resource to
neighboring femtocells. This scenario may induce co-channel
interference and may seriously affect the service quality of
neighboring femtocells. In addition, the dominant transmit power of a
femtocell will induce co-tier interference to neighboring femtocells.
Thus to jointly handle co-tier and co-channel interference, we
propose an interference-free power and resource block allocation
(IFPRBA) algorithm for closely located, closed access femtocells.
Based on neighboring list, inter-femto-base station distance and
uplink noise power, the IFPRBA algorithm assigns non-interfering
power and resource to femtocells. The IFPRBA algorithm also
guarantees the quality of service to femtouser based on the
knowledge of resource requirement, connection type, and the
tolerable delay budget. Simulation result shows that the interference
power experienced in IFPRBA algorithm is below the tolerable
interference power and hence the overall service success ratio, PRB
efficiency and network throughput are maximum when compared to
conventional resource allocation framework for femtocell (RAFF)
algorithm.