Abstract: Methicillin/multiple-resistant Staphylococcus aureus
(MRSA) are infectious bacteria that are resistant to common
antibiotics. A previous in silico study in our group has identified a
hypothetical protein SAV1226 as one of the potential drug targets. In
this study, we reported the bioinformatics characterization, as well as
cloning, expression, purification and kinetic assays of hypothetical
protein SAV1226 from methicillin/vancomycin-resistant
Staphylococcus aureus Mu50 strain. MALDI-TOF/MS analysis
revealed a low degree of structural similarity with known proteins.
Kinetic assays demonstrated that hypothetical protein SAV1226 is
neither a domain of an ATP dependent dihydroxyacetone kinase nor
of a phosphotransferase system (PTS) dihydroxyacetone kinase,
suggesting that the function of hypothetical protein SAV1226 might
be misannotated on public databases such as UniProt and
InterProScan 5.
Abstract: This paper discusses the forensic investigation of a
fatality-involved catastrophic structure collapse and the special
challenges faced when tasked with directing such an effort. While
this paper discusses the investigation’s findings and the outcome of
the event; this paper’s primary focus is on the challenges faced
directing a forensic investigation that requires coordinating with
governmental oversight while also having to accommodate multiple
parties’ investigative teams. In particular the challenges discussed
within this paper included maintaining on-site safety and operations
while accommodating outside investigator’s interests. In addition this
paper discusses unique challenges that one may face such as what to
do about unethical conduct of interested party’s investigative teams,
“off the record” sharing of information, and clandestinely transmitted
evidence.
Abstract: Community integration is a construct that an
increasing body of research has shown to have a significant impact
on the wellbeing and recovery of people with psychiatric problems.
However, there are few studies that explore which factors can be
associated and predict community integration. Moreover, community
integration has been mostly studied in minority groups, and current
literature on the definition and manifestation of community
integration in the general population is scarcer. Thus, the current
study aims to characterize community integration and explore
possible predictor variables in a sample of participants with
psychiatric problems (PP, N=183) and a sample of participants from
the general population (GP, N=211).
Results show that people with psychiatric problems present above
average values of community integration, but are significantly lower
than their healthy counterparts. It was also possible to observe that
community integration does not vary in terms of the sociodemographic
characteristics of both groups in this study. Correlation
and multiple regression showed that, among several variables that
literature present as relevant in the community integration process,
only three variables emerged as having the most explanatory value in
community integration of both groups: sense of community, basic
needs satisfaction and submission. These results also shown that
those variables have increased explanatory power in the PP sample,
which leads us to emphasize the need to address this issue in future
studies and increase the understanding of the factors that can be
involved in the promotion of community integration, in order to
devise more effective interventions in this field.
Abstract: The 5th generation of mobile networks is term used in
various research papers and projects to identify the next major phase
of mobile telecommunications standards. 5G wireless networks will
support higher peak data rate, lower latency and provide best
connections with QoS guarantees.
In this article, we discuss various promising technologies for 5G
wireless communication systems, such as IPv6 support, World Wide
Wireless Web (WWWW), Dynamic Adhoc Wireless Networks
(DAWN), BEAM DIVISION MULTIPLE ACCESS (BDMA), Cloud
Computing, cognitive radio technology and FBMC/OQAM.
This paper is organized as follows: First, we will give introduction
to 5G systems, present some goals and requirements of 5G. In the
next, basic differences between 4G and 5G are given, after we talk
about key technology innovations of 5G systems and finally we will
conclude in last Section.
Abstract: In this paper, a summary of analytical and
experimental studies into the behavior of a new hysteretic damper,
designed for seismic protection of structures is presented. The Multidirectional
Torsional Hysteretic Damper (MRSD) is a patented
invention in which a symmetrical arrangement of identical cylindrical
steel cores is so configured as to yield in torsion while the structure
experiences planar movements due to earthquake shakings. The new
device has certain desirable properties. Notably, it is characterized by
a variable and controllable-via-design post-elastic stiffness. The
mentioned property is a result of MRSD’s kinematic configuration
which produces this geometric hardening, rather than being a
secondary large-displacement effect. Additionally, the new system is
capable of reaching high force and displacement capacities, shows
high levels of damping, and very stable cyclic response. The device
has gone through many stages of design refinement, multiple
prototype verification tests and development of design guide-lines
and computer codes to facilitate its implementation in practice.
Practicality of the new device, as offspring of an academic sphere, is
assured through extensive collaboration with industry in its final
design stages, prototyping and verification test programs.
Abstract: Auditory hallucinations among the most invalidating
and distressing experiences reported by patients diagnosed with
schizophrenia, leading to feelings of powerlessness and helplessness
towards their illness. In more severe cases, these auditory
hallucinations can take the form of commanding voices, which are
often related to high suicidality rates in these patients. Several
authors propose that the meanings attributed to the hallucinatory
experience, rather than characteristics like form and content, can be
determinant in patients’ reactions to hallucinatory activity,
particularly in the case of voice-hearing experiences. In this study, 48
patients diagnosed with paranoid schizophrenia presenting auditory
hallucinations were studied. Multiple regression analyses were
computed to study the influence of several developmental aspects,
such as family and social dynamics, bullying, depression, and sociocognitive
variables on the auditory hallucinations, on patients’
attributions and relationships with their voices, and on the resulting
invalidation of hallucinatory experience. Overall, results showed how
relationships with voices can mirror several aspects of interpersonal
relationship with others, and how self-schemas, depression and actual
social relationships help shaping the voice-hearing experience. Early
experiences of victimization and submission help predict the
attributions of omnipotence of the voices, and increased hostility
from parents seems to increase the malevolence of the voices,
suggesting that socio-cognitive factors can significantly contribute to
the etiology and maintenance of auditory hallucinations. The
understanding of the characteristics of auditory hallucinations and the
relationships patients established with their voices can allow the
development of more promising therapeutic interventions that can be
more effective in decreasing invalidation caused by this devastating
mental illness.
Abstract: This paper describes an optimization tool-based
design strategy for a Current Mode Logic CML divide-by-2 circuit.
Representing a building block for output frequency generation in a
RFID protocol based-frequency synthesizer, the circuit was designed
to minimize the power consumption for driving of multiple loads
with unbalancing (at transceiver level). Implemented with XFAB
XC08 180 nm technology, the circuit was optimized through
MunEDA WiCkeD tool at Cadence Virtuoso Analog Design
Environment ADE.
Abstract: We present a refined multiscale Shannon entropy for
analyzing electroencephalogram (EEG), which reflects the underlying
dynamics of EEG over multiple scales. The rationale behind
this method is that neurological signals such as EEG possess
distinct dynamics over different spectral modes. To deal with the
nonlinear and nonstationary nature of EEG, the recently developed
empirical mode decomposition (EMD) is incorporated, allowing a
decomposition of EEG into its inherent spectral components, referred
to as intrinsic mode functions (IMFs). By calculating the Shannon
entropy of IMFs in a time-dependent manner and summing them over
adaptive multiple scales, it results in an adaptive subscale entropy
measure of EEG. Simulation and experimental results show that
the proposed entropy properly reveals the dynamical changes over
multiple scales.
Abstract: The paper presents new results concerning selection of
optimal information fusion formula for ensembles of C-OTDR
channels. The goal of information fusion is to create an integral
classificator designed for effective classification of seismoacoustic
target events. The LPBoost (LP-β and LP-B variants), the Multiple
Kernel Learning, and Weighing of Inversely as Lipschitz Constants
(WILC) approaches were compared. The WILC is a brand new
approach to optimal fusion of Lipschitz Classifiers Ensembles.
Results of practical usage are presented.
Abstract: The Orthogonal Frequency Division Multiplexing
(OFDM) with high data rate, high spectral efficiency and its ability to
mitigate the effects of multipath makes them most suitable in wireless
application. Impulsive noise distorts the OFDM transmission and
therefore methods must be investigated to suppress this noise. In this
paper, a State Space Recursive Least Square (SSRLS) algorithm
based adaptive impulsive noise suppressor for OFDM
communication system is proposed. And a comparison with another
adaptive algorithm is conducted. The state space model-dependent
recursive parameters of proposed scheme enables to achieve steady
state mean squared error (MSE), low bit error rate (BER), and faster
convergence than that of some of existing algorithm.
Abstract: We propose new multiple-channel piezoelectric (PZT)
actuated tunable optical filter based on racetrack multi-ring
resonators for wavelength de-multiplexing network applications. We
design tunable eight-channel wavelength de-multiplexer consisting of
eight cascaded PZT actuated tunable multi-ring resonator filter with a
channel spacing of 1.6nm. The filter for each channel is basically
structured on a suspended beam, sandwiched with piezoelectric
material and built in integrated ring resonators which are placed on
the middle of the beam to gain uniform stress and linearly varying
longitudinal strain. A reference single mode serially coupled multi
stage racetrack ring resonator with the same radii and coupling length
is designed with a line width of 0.8974nm with a flat top pass band at
1dB of 0.5205nm and free spectral range of about 14.9nm. In each
channel, a small change in the perimeter of the rings is introduced to
establish the shift in resonance wavelength as per the defined channel
spacing. As a result, when a DC voltage is applied, the beams will
elongate, which involves mechanical deformation of the ring
resonators that induces a stress and a strain, which brings a change in
refractive index and perimeter of the rings leading to change in the
output spectrum shift providing the tunability of central wavelength
in each channel. Simultaneous wave length shift as high as
45.54pm/
Abstract: Edge is variation of brightness in an image. Edge
detection is useful in many application areas such as finding forests,
rivers from a satellite image, detecting broken bone in a medical
image etc. The paper discusses about finding edge of multiple aerial
images in parallel. The proposed work tested on 38 images 37
colored and one monochrome image. The time taken to process N
images in parallel is equivalent to time taken to process 1 image in
sequential. Message Passing Interface (MPI) and Open Computing
Language (OpenCL) is used to achieve task and pixel level
parallelism respectively.
Abstract: Prosperity of electronic equipment in photocopying
environment not only has improved work efficiency, but also has
changed indoor air quality. Considering the number of photocopying
employed, indoor air quality might be worse than in general office
environments. Determining the contribution from any type of
equipment to indoor air pollution is a complex matter. Non-methane
hydrocarbons are known to have an important role on air quality due
to their high reactivity. The presence of hazardous pollutants in
indoor air has been detected in one photocopying shop in Novi Sad,
Serbia. Air samples were collected and analyzed for five days, during
8-hr working time in three time intervals, whereas three different
sampling points were determined. Using multiple linear regression
model and software package STATISTICA 10 the concentrations of
occupational hazards and microclimates parameters were mutually
correlated. Based on the obtained multiple coefficients of
determination (0.3751, 0.2389 and 0.1975), a weak positive
correlation between the observed variables was determined. Small
values of parameter F indicated that there was no statistically
significant difference between the concentration levels of nonmethane
hydrocarbons and microclimates parameters. The results
showed that variable could be presented by the general regression
model: y = b0 + b1xi1+ b2xi2. Obtained regression equations allow to
measure the quantitative agreement between the variables and thus
obtain more accurate knowledge of their mutual relations.
Abstract: The purpose of this study was to develop a descriptive
profile of the adapted physical activity research using single subject
experimental designs. All research articles using single subject
experimental designs published in the journal of Adapted Physical
Activity Quarterly from 1984 to 2013 were employed as the data
source. Each of the articles was coded in a subcategory of seven
categories: (a) the size of sample; (b) the age of participants; (c) the
type of disabilities; (d) the type of data analysis; (e) the type of
designs, (f) the independent variable, and (g) the dependent variable.
Frequencies, percentages, and trend inspection were used to analyze
the data and develop a profile. The profile developed characterizes a
small portion of research articles used single subject designs, in
which most researchers used a small sample size, recruited children
as subjects, emphasized learning and behavior impairments, selected
visual inspection with descriptive statistics, preferred a multiple
baseline design, focused on effects of therapy, inclusion, and
strategy, and measured desired behaviors more often, with a
decreasing trend over years.
Abstract: This paper analyzes the conceptual framework of three
statistical methods, multiple regression, path analysis, and structural
equation models. When establishing research model of the statistical
modeling of complex social phenomenon, it is important to know the
strengths and limitations of three statistical models. This study
explored the character, strength, and limitation of each modeling and
suggested some strategies for accurate explaining or predicting the
causal relationships among variables. Especially, on the studying of
depression or mental health, the common mistakes of research
modeling were discussed.
Abstract: Introduction: There are multiple social, individual and
cultural factors that influence an individual’s decision to adopt family
planning methods especially among non-users in patriarchal societies
like Pakistan. Non-users, if targeted efficiently, can contribute
significantly to country’s CPR. A research study showed that nonusers
if convinced to adopt lactational amenorrhea method can shift
to long term methods in future. Research shows that if non users are
targeted efficiently a 59% reduction in unintended pregnancies in
Saharan Africa and South-Central and South-East Asia is anticipated.
Methods: We did secondary data analysis on Pakistan
Demographic Heath Survey (2012-13) dataset. Use of contraception
(never-use/ever-use) was the outcome variable. At univariate level
Chi-square/Fisher Exact test was used to assess relationship of
baseline covariates with contraception use. Then variables to be
incorporated in the model were checked for multicollinearity,
confounding and interaction. Then binary logistic regression (with an
urban-rural stratification) was done to find relationship between
contraception use and baseline demographic and social variables.
Results: The multivariate analyses of the study showed that
younger women (≤ 29 years)were more prone to be never users as
compared to those who were >30 years and this trend was seen in
urban areas (AOR 1.92, CI 1.453-2.536) as well as rural areas (AOR
1.809, CI 1.421-2.303). While looking at regional variation, women
from urban Sindh (AOR 1.548, CI 1.142-2.099) and urban
Balochistan (AOR 2.403, CI 1.504-3.839) had more never users as
compared to other urban regions. Women in the rich wealth quintile
were more never users and this was seen both in urban and rural
localities (urban (AOR 1.106 CI .753-1.624); rural areas (AOR 1.162,
CI .887-1.524)) even though these were not statistically significant.
Women idealizing more children (>4) are more never users as
compared to those idealizing less children in both urban (AOR 1.854,
CI 1.275-2.697) and rural areas (AOR 2.101, CI 1.514-2.916).
Women who never lost a pregnancy were more inclined to be nonusers
in rural areas (AOR 1.394, CI 1.127-1.723) .Women familiar
with only traditional or no method had more never users in rural areas
(AOR 1.717, CI 1.127-1.723) but in urban areas it wasn’t significant.
Women unaware of Lady Health Worker’s presence in their area
were more never users especially in rural areas (AOR 1.276, CI
1.014-1.607). Women who did not visit any care provider were more
never users (urban (AOR 11.738, CI 9.112-15.121) rural areas (AOR
7.832, CI 6.243-9.826)).
Discussion/Conclusion: This study concluded that government,
policy makers and private sector family planning programs should
focus on the untapped pool of never users (younger women from underserved provinces, in higher wealth quintiles, who desire more
children.). We need to make sure to cover catchment areas where
there are less LHWs and less providers as ignorance to modern
methods and never been visited by an LHW are important
determinants of never use. This all is in sync with previous literate
from similar developing countries.
Abstract: This study attempts to identify the factors influencing
on women empowerment of rural area in Sri Lanka through micro
finance services. Data were collected from one hundred (100) rural
women involving self-employment activities through a questionnaire
using direct personal interviews. Judgment and Convenience Random
sampling technique was used to select the sample size from three
Divisional Secretariat divisions of Kandawalai, Poonakari and
Karachchi in Kilinochchi District. The factor analysis was performed
on fourteen (14) variables for screening and reducing the variables to
identify the influencing factors on empowerment. Multiple regression
analysis was used to identify the relationship between the three
empowerment factors and the impact of micro finance on overall
empowerment of rural women. The result of this study summarized
the variables into three factors namely decision making, freedom to
mobility and family support and which are positively associated with
empowerment. In addition to this the value of adjusted R2 is 0.248
indicates that all the variables extracted can be explained 24.8% of
the variation in the women empowerment through microfinance.
Independent variables of these three factors have positive correlation
with women empowerment as well as significant values at 5 percent
level.
Abstract: Recently, there is a lot of interest in the field of under
water optical wireless communication for short range because of
its high bandwidth. But in most of the previous works line of
sight propagation or single scattering of photons only considered.
In practical case this is not applicable because of beam blockage in
underwater and multiple scattering also occurred during the photons
propagation through water. In this paper we consider a non-line
of sight underwater wireless optical communication system with
multiple scattering and examine the performance of the system using
monte carlo simulation. The distribution scattering angle of photons
are modeled by Henyey-Greenstein method. The average bit error
rate is calculated using on-off keying modulation for different water
types.
Abstract: An Australian manufacturer has fabricated an
innovative GFRP sandwich panel made from E-glass fiber skin and a
modified phenolic core for structural applications. Debonding, which
refers to separation of skin from the core material in composite
sandwiches, is one of the most common types of damage in
composites. The presence of debonding is of great concern because it
not only severely affects the stiffness but also modifies the dynamic
behaviour of the structure. Generally it is seen that the majority of
research carried out has been concerned about the delamination of
laminated structures whereas skin-core debonding has received
relatively minor attention. Furthermore it is observed that research
done on composite slabs having multiple skin-core debonding is very
limited. To address this gap, a comprehensive research investigating
dynamic behaviour of composite panels with single and multiple
debonding is presented. The study uses finite-element modelling and
analyses for investigating the influence of debonding on free
vibration behaviour of single and multilayer composite sandwich
panels. A broad parametric investigation has been carried out by
varying debonding locations, debonding sizes and support conditions
of the panels in view of both single and multiple debonding.
Numerical models were developed with Strand7 finite element
package by innovatively selecting the suitable elements to diligently
represent their actual behavior. Three-dimensional finite element
models were employed to simulate the physically real situation as
close as possible, with the use of an experimentally and numerically
validated finite element model. Comparative results and conclusions
based on the analyses are presented. For similar extents and locations
of debonding, the effect of debonding on natural frequencies appears
greatly dependent on the end conditions of the panel, giving greater
decrease in natural frequency when the panels are more restrained.
Some modes are more sensitive to debonding and this sensitivity
seems to be related to their vibration mode shapes. The fundamental
mode seems generally the least sensitive mode to debonding with
respect to the variation in free vibration characteristics. The results
indicate the effectiveness of the developed three dimensional finite
element models in assessing debonding damage in composite
sandwich panels.
Abstract: Association rule mining is one of the most important fields of data mining and knowledge discovery. In this paper, we propose an efficient multiple support frequent pattern growth algorithm which we called “MSFP-growth” that enhancing the FPgrowth algorithm by making infrequent child node pruning step with multiple minimum support using maximum constrains. The algorithm is implemented, and it is compared with other common algorithms: Apriori-multiple minimum supports using maximum constraints and FP-growth. The experimental results show that the rule mining from the proposed algorithm are interesting and our algorithm achieved better performance than other algorithms without scarifying the accuracy.