Abstract: Dexamethasone (Dex) is a synthetic glucocorticoid
that is used in therapy. However prolonged treatments with high
doses are often required. This causes side effects that interfere with
the activity of several endocrine systems, including the gonadotropic
axis.
The aim of our study is to determine the effect of Dex on testicular
function in prepubertal Wistar rats.
Newborn Wistar rats are submitted to intraperitoneal injection of
Dex (1μg of Dex dissolved in NaCl 0.9% / 5g bw) for 20 days and
then sacrificed at the age of 40days. A control group received NaCl
0.9%. The rat is weighed daily. The plasmatic levels of testosterone,
LH and FSH were measured by radioimmunoassay. A histomorphometric
study was performed on sections of testis.
Treated groups showed a significant decrease in body weight (p
Abstract: The aim of this study was to estimate the frequency of
EBV infection in Hodgkin's lymphoma (HL) and non-Hodgkin's
lymphoma (NHL) occurring in Jordanian patients. A total of 55
patients with lymphoma were examined in this study. Of 55 patients,
30 and 25 were diagnosed as HL and NHL, respectively. The four
HL subtypes were observed with the majority of the cases exhibited
the mixed cellularity (MC) subtype followed by the nodular sclerosis
(NS). The high grade was found to be the commonest subtype of
NHL in our sample, followed by the low grade. The presence of EBV
virus was detected by immunostating for expression of latent
membrane protein-1 (LMP-1). The frequency of LMP-1 expression
occurred more frequent in patients with HL (60.0%) than in patients
with NHL (32.0%). The frequency of LMP-1 expression was also
higher in patients with MC subtype (61.11%) than those patients with
NS (28.57%). No age or gender difference in occurrence of EBV
infection was observed among patient with HL. By contrast, the
prevalence of EBV infection in NHL patients aged below 50 was
lower (16.66%) than in NHL patients aged 50 or above (46.15%). In
addition, EBV infection was more frequent in females with NHL
(38.46%) than in male with NHL (25%). In NHL cases, the
frequency of EBV infection in intermediate grade (60.0%) was high
when compared with frequency of low (25%) or high grades (25%).
In conclusion, analysis of LMP-1 expression indicates an important
role for this viral oncogene in the pathogenesis of EBV-associated
malignant lymphomas. These data also support the previous findings
that people with EBV may develop lymphoma and that efforts to
maintain low lymphoma should be considered for people with EBV
infection.
Abstract: Organizations are supposed to be systems and
consequently require defining the notion of equilibrium within.
However, organizations comprise people and unavoidably entail their
irrational aspects. Then, the question is what is the organizational
equilibrium and equilibrating mechanisms considering these aspects.
Hence, some arguments are provided here to conceptualize human
unconsciousness, irrationalities and consequent uncertainties within
organizations in the form of a system of psychic dynamism. The
assumption is this dynamism maintains the psychic balance of the
organization through a psychodynamic point of view. The resultant
conceptualization expected to promote the understanding of such
aspects in different organizational settings by hypothesizing
organizational equilibration from this perspective. As a result, the
main expectation is, if it is known that how the organization
equilibrates in this sense, we can explain and deal with such
irrationalities and unconsciousness by rational and, of course
conscious, planning and accomplishing.
Abstract: The use of the mechanical simulation (in particular the finite element analysis) requires the management of assumptions in order to analyse a real complex system. In finite element analysis (FEA), two modeling steps require assumptions to be able to carry out the computations and to obtain some results: the building of the physical model and the building of the simulation model. The simplification assumptions made on the analysed system in these two steps can generate two kinds of errors: the physical modeling errors (mathematical model, domain simplifications, materials properties, boundary conditions and loads) and the mesh discretization errors. This paper proposes a mesh adaptive method based on the use of an h-adaptive scheme in combination with an error estimator in order to choose the mesh of the simulation model. This method allows us to choose the mesh of the simulation model in order to control the cost and the quality of the finite element analysis.
Abstract: In the present study, development of salbutamol
sulphate nanoparticles that adhere to gastric mucus was investigated.
Salbutamol sulphate has low bioavailability due to short transit time in
gastric. It also has a positive surface charge that provides hurdles to be
encapsulated by the positively strong mucoadhesive polymer of
chitosan. To overcome the difficulties, the surface charge of active
ingredient was modified using several nonionic and anionic
stomach-specific polymers. The nanoparticles were prepared using
ionotropic gelation technique. The evaluation involved determination
of particle size, zeta potential, entrapment efficiency, in vitro drug
release and in vitro mucoadhesion test. Results exhibited that the use
of anionic alginate polymer was more satisfactory than that of
nonionic polymer. Characteristics of the particles was nano-size, high
encapsulation efficiency, fulfilled the drug release requirements and
adhesive towards stomach for around 11 hours. This result shows that
the salbutamol sulphate nanoparticles can be utilized for improvement
its delivery.
Abstract: The purpose of this research is to develop and apply the
RSCMAC to enhance the dynamic accuracy of Global Positioning
System (GPS). GPS devices provide services of accurate positioning,
speed detection and highly precise time standard for over 98% area on
the earth. The overall operation of Global Positioning System includes
24 GPS satellites in space; signal transmission that includes 2
frequency carrier waves (Link 1 and Link 2) and 2 sets random
telegraphic codes (C/A code and P code), on-earth monitoring stations
or client GPS receivers. Only 4 satellites utilization, the client position
and its elevation can be detected rapidly. The more receivable
satellites, the more accurate position can be decoded. Currently, the
standard positioning accuracy of the simplified GPS receiver is greatly
increased, but due to affected by the error of satellite clock, the
troposphere delay and the ionosphere delay, current measurement
accuracy is in the level of 5~15m. In increasing the dynamic GPS
positioning accuracy, most researchers mainly use inertial navigation
system (INS) and installation of other sensors or maps for the
assistance. This research utilizes the RSCMAC advantages of fast
learning, learning convergence assurance, solving capability of
time-related dynamic system problems with the static positioning
calibration structure to improve and increase the GPS dynamic
accuracy. The increasing of GPS dynamic positioning accuracy can be
achieved by using RSCMAC system with GPS receivers collecting
dynamic error data for the error prediction and follows by using the
predicted error to correct the GPS dynamic positioning data. The
ultimate purpose of this research is to improve the dynamic positioning
error of cheap GPS receivers and the economic benefits will be
enhanced while the accuracy is increased.
Abstract: The heavy metal contamination of the technogenous
sediments and soils at the investigated dump-field show irregular
planar distribution. Also the heavy metal content in the surface water,
drainage water and in the groundwater was studied both in the dry as
well as during the rainy periods. The cementation process causes
substitution of iron by copper. Natural installation and development
of plant species was observed at the old mine waste dumps, specific
to the local chemical conditions such as low content of essential
nutrients and high content of heavy metals. The individual parts of
the plant tissues (roots, branches/stems, leaves/needles, flowers/
fruits) are contaminated by heavy metals and tissues are damaged
differently, respectively.
Abstract: This experiment was conducted to investigate the
effect of dietary supplementation of different levels of black seed
(Nigella sativa L.) on the performance and immune response of broiler chicks. A total 240 day-old broiler chicks were used and
randomly allotted equally into six experimental groups designated as 1, 2, 3, 4, 5 and 6 having black seed at the rate of 0, 2, 4, 6, 8 and
10 g /kg diet respectively. The study was lasted for 42 days. Average body weight, weight gain, relative growth rate, feed
conversion, antibody titer against Newcastle disease, phagocytic activity and phagocytic index, some blood parameters(GOT, GPT,
Glucose, Cholesterol, Triglyceride, Total protein, Albumen, WBCs,
RBCs, Hb and PCV), dressing percentage, weight of different body
organs, abdominal fat weight, were determined. It was found that, N. Sativa significantly improved final body weight, total body gain
and feed conversion ratio of groups 2 and 3 when compared with the control group. Higher levels of N. Sativa did not improve
growth performance of the chicks. Non significant differences were
observed for antibody titer against Newcastle virus, WBCs count,
serum GOT, glucose level, dressing %, relative liver, spleen, heart and head percentages. Lymphoid organs (Bursa and Thymus)
improved significantly with increasing N. Sativa level in all supplemented groups. Serum cholesterol, triglyceride and visible fat
% significantly decreased with Nigella sativa supplementation while
serum GPT level significantly increased with nigella sativa
supplementation.
Abstract: Information and communication service providers
(ICSP) that are significant in size and provide Internet-based services
take administrative, technical, and physical protection measures via
the information security check service (ISCS). These protection
measures are the minimum action necessary to secure the stability and
continuity of the information and communication services (ICS) that
they provide. Thus, information assets are essential to providing ICS,
and deciding the relative importance of target assets for protection is a
critical procedure. The risk analysis model designed to decide the
relative importance of information assets, which is described in this
study, evaluates information assets from many angles, in order to
choose which ones should be given priority when it comes to
protection. Many-sided risk analysis (MSRS) grades the importance of
information assets, based on evaluation of major security check items,
evaluation of the dependency on the information and communication
facility (ICF) and influence on potential incidents, and evaluation of
major items according to their service classification, in order to
identify the ISCS target. MSRS could be an efficient risk analysis
model to help ICSPs to identify their core information assets and take
information protection measures first, so that stability of the ICS can
be ensured.
Abstract: Problem solving has traditionally been one of the principal research areas for artificial intelligence. Yet, although artificial intelligence reasoning techniques have been employed in several product support systems, the benefit of integrating product support, knowledge engineering, and problem solving, is still unclear. This paper studies the synergy of these areas and proposes a knowledge engineering framework that integrates product support systems and artificial intelligence techniques. The framework includes four spaces; the data, problem, hypothesis, and solution ones. The data space incorporates the knowledge needed for structured reasoning to take place, the problem space contains representations of problems, and the hypothesis space utilizes a multimodal reasoning approach to produce appropriate solutions in the form of virtual documents. The solution space is used as the gateway between the system and the user. The proposed framework enables the development of product support systems in terms of smaller, more manageable steps while the combination of different reasoning techniques provides a way to overcome the lack of documentation resources.
Abstract: Tourism industry is an important sector in Malaysia economy and this motivates the examination of long-run relationships between tourist arrivals from three selected European countries in Malaysia and four possible determinants; relative prices, exchange rates, transportation cost and relative prices of substitute destination. The study utilizes data from January 1999 to September 2008 and employs standard econometric techniques that include unit root test and cointegration test. The estimated demand model indicates that depreciation of local currency and increases in prices at substitute destination have positive impact on tourist arrivals while increase in transportation cost has negative impact on tourist arrivals. In addition, the model suggests that higher rate of increase in local prices relative to prices at tourist country of origin may not deter tourists from coming to Malaysia
Abstract: Wavelet neural networks (WNNs) have emerged as a vital alternative to the vastly studied multilayer perceptrons (MLPs) since its first implementation. In this paper, we applied various clustering algorithms, namely, K-means (KM), Fuzzy C-means (FCM), symmetry-based K-means (SBKM), symmetry-based Fuzzy C-means (SBFCM) and modified point symmetry-based K-means (MPKM) clustering algorithms in choosing the translation parameter of a WNN. These modified WNNs are further applied to the heterogeneous cancer classification using benchmark microarray data and were compared against the conventional WNN with random initialization method. Experimental results showed that a WNN classifier with the MPKM algorithm is more precise than the conventional WNN as well as the WNNs with other clustering algorithms.
Abstract: In the present work, we introduce the particle swarm optimization called (PSO in short) to avoid the Runge-s phenomenon occurring in many numerical problems. This new approach is tested with some numerical examples including the generalized integral quadrature method in order to solve the Volterra-s integral equations
Abstract: In elevating performance in competetive sports, an
athlete must continously train in achieving maximum
performance,but needs to pay attention to recovery therapy, that is to
recover from fatigue as well as injury.The correct recovery therapy
will assist in process of recovery and helps in the training in
achieving better performace. Binahong (Anredera cordifolia) was
proven empirically by the locals in assisting speedy recovery from an
injury.Clinical research with lab animals receiving blunt trauma
injury, microscopically shown signs of: 1) redness, 2) heatiness, 3)
swelling and, 4) lack of activity. There is also microscopic indication
of: 1) infiltration of inflame cells (migration of cells to the trauma
area), 2) Cells necrosis, 3) Congestion (as a result of dead red blood
cells), 4) uedema. On administration of Binahong for 3 days, there is
a significant drop of 5% in cell inflammation, 2% increase of
fibroblast (cell membrance) count.Conclutin: Binahong do assist in
reducing cell inflammation and increase counts of cells fibroblast.
Suggestion: In helping athlete's to recover from force injury, we need
study about Binahong's roots to inflammation cell and healing of
injuried cell.
Abstract: Knowledge of an organization does not merely reside
in structured form of information and data; it is also embedded in
unstructured form. The discovery of such knowledge is particularly
difficult as the characteristic is dynamic, scattered, massive and
multiplying at high speed. Conventional methods of managing
unstructured information are considered too resource demanding and
time consuming to cope with the rapid information growth.
In this paper, a Multi-faceted and Automatic Knowledge
Elicitation System (MAKES) is introduced for the purpose of
discovery and capture of organizational knowledge. A trial
implementation has been conducted in a public organization to
achieve the objective of decision capture and navigation from a
number of meeting minutes which are autonomously organized,
classified and presented in a multi-faceted taxonomy map in both
document and content level. Key concepts such as critical decision
made, key knowledge workers, knowledge flow and the relationship
among them are elicited and displayed in predefined knowledge
model and maps. Hence, the structured knowledge can be retained,
shared and reused.
Conducting Knowledge Management with MAKES reduces work
in searching and retrieving the target decision, saves a great deal of
time and manpower, and also enables an organization to keep pace
with the knowledge life cycle. This is particularly important when
the amount of unstructured information and data grows extremely
quickly. This system approach of knowledge management can
accelerate value extraction and creation cycles of organizations.
Abstract: This paper present an efficient and reliable technique of optimization which combined fuel cost economic optimization and emission dispatch using the Sigmoid Decreasing Inertia Weight Particle Swarm Optimization algorithm (PSO) to reduce the cost of fuel and pollutants resulting from fuel combustion by keeping the output of generators, bus voltages, shunt capacitors and transformer tap settings within the security boundary. The performance of the proposed algorithm has been demonstrated on IEEE 30-bus system with six generating units. The results clearly show that the proposed algorithm gives better and faster speed convergence then linearly decreasing inertia weight.
Abstract: Nanocrystalline thin film of Na0.1V2O5.nH2O xerogel
obtained by sol gel synthesis was used as gas sensor. Gas sensing
properties of different gases such as hydrogen, petroleum and
humidity were investigated. Applying XRD and TEM the size of the
nanocrystals is found to be 7.5 nm. SEM shows a highly porous
structure with submicron meter-sized voids present throughout the
sample. FTIR measurement shows different chemical groups
identifying the obtained series of gels. The sample was n-type
semiconductor according to the thermoelectric power and electrical
conductivity. It can be seen that the sensor response curves from
130oC to 150oC show a rapid increase in sensitivity for all types of
gas injection, low response values for heating period and the rapid
high response values for cooling period. This result may suggest that
this material is able to act as gas sensor during the heating and
cooling process.
Abstract: The nature, prevalence, cellular composition of
leukocyte infiltrates and immunohistochemical characteristics of
their constituent cells in the liver of patients with chronic viral
hepatitis B and C were investigated. It was found that the area of
distribution and cellular composition of infiltrates depended on the
virus type and process activity. The expediency of
immunohistochemical study using leukocyte infiltrates from liver
biopsies of patients with viral hepatitis aimed at clarifying diagnosis,
making prognosis, and choice of optimal treatment with elements of
immune correction is emphasized.
Abstract: The paper presents a modelling methodology for
small scale multi-source renewable energy systems. Using historical
site-specific weather data, the relationships of cost, availability and
energy form are visualised as a function of the sizing of photovoltaic
arrays, wind turbines, and battery capacity. The specific dependency
of each site on its own particular weather patterns show that unique
solutions exist for each site. It is shown that in certain cases the
capital component cost can be halved if the desired theoretical
demand availability is reduced from 100% to 99%.
Abstract: In this paper, optimal generation expansion planning (GEP) is investigated considering purchase prices, profits of independent power producers (IPPs) and reliability criteria using a new method based on hybrid coded Genetic Algorithm (GA) and Particle Swarm Optimization (PSO). In this approach, optimal purchase price of each IPP is obtained by HCGA and reliability criteria are calculated by PSO technique. It should be noted that reliability criteria and the rate of carbon dioxide (CO2) emission have been considered as constraints of the GEP problem. Finally, the proposed method has been tested on the case study system. The results evaluation show that the proposed method can simply obtain optimal purchase prices of IPPs and is a fast method for calculation of reliability criteria in expansion planning. Also, considering the optimal purchase prices and profits of IPPs in generation expansion planning are caused that the expansion costs are decreased and the problem is solved more exactly.