Abstract: Single nucleotide polymorphisms (SNPs) hold much promise as a basis for disease-gene association. However, research is limited by the cost of genotyping the tremendous number of SNPs. Therefore, it is important to identify a small subset of informative SNPs, the so-called tag SNPs. This subset consists of selected SNPs of the genotypes, and accurately represents the rest of the SNPs. Furthermore, an effective evaluation method is needed to evaluate prediction accuracy of a set of tag SNPs. In this paper, a genetic algorithm (GA) is applied to tag SNP problems, and the K-nearest neighbor (K-NN) serves as a prediction method of tag SNP selection. The experimental data used was taken from the HapMap project; it consists of genotype data rather than haplotype data. The proposed method consistently identified tag SNPs with considerably better prediction accuracy than methods from the literature. At the same time, the number of tag SNPs identified was smaller than the number of tag SNPs in the other methods. The run time of the proposed method was much shorter than the run time of the SVM/STSA method when the same accuracy was reached.
Abstract: The potential of economically cheaper cellulose
containing natural materials like rice husk was assessed for nickel
adsorption from aqueous solutions. The effects of pH, contact time,
sorbent dose, initial metal ion concentration and temperature on the
uptake of nickel were studied in batch process. The removal of nickel
was dependent on the physico-chemical characteristics of the
adsorbent, adsorbate concentration and other studied process
parameters. The sorption data has been correlated with Langmuir,
Freundlich and Dubinin-Radush kevich (D-R) adsorption models. It
was found that Freundlich and Langmuir isotherms fitted well to the
data. Maximum nickel removal was observed at pH 6.0. The
efficiency of rice husk for nickel removal was 51.8% for dilute
solutions at 20 g L-1 adsorbent dose. FTIR, SEM and EDAX were
recorded before and after adsorption to explore the number and
position of the functional groups available for nickel binding on to
the studied adsorbent and changes in surface morphology and
elemental constitution of the adsorbent. Pseudo-second order model
explains the nickel kinetics more effectively. Reusability of the
adsorbent was examined by desorption in which HCl eluted 78.93%
nickel. The results revealed that nickel is considerably adsorbed on
rice husk and it could be and economic method for the removal of
nickel from aqueous solutions.
Abstract: The aim of this study is to discuss the relationship between tourist awareness of environmental issues and their own recreational behaviors in the Taipei Guandu Wetland. A total of 392 questionnaires were gathered for data analysis using descriptive statistics, t-testing, one-way analysis of variance (ANOVA) and least significant difference (LSD) post hoc comparisons. The results showed that most of the visitors there enjoying the beautiful scenery are 21 to 30 years old with a college education. The means and standard deviations indicate that tourists express a positive degree of cognition of environmental issues and recreational behaviors. They suggest that polluting the environment is harmful to the natural ecosystem and that the natural resources of ecotourism are fragile, as well as expressing a high degree of recognition of the need to protect wetlands. Most of respondents are cognizant of the regulations proposed by the Guandu Wetland administration which asks that users exercise self-control and follow recommended guidelines when traveling the wetland. There were significant differences in the degree of cognition related to the variables of age, number of visits and reasons for visiting. We found that most respondents with relatively high levels of education would like to learn more about the wetland and are supportive of its conservation.
Abstract: Since polymerase chain reaction (PCR) has been
invented, it has emerged as a powerful tool in genetic analysis. The
PCR products are closely linked with thermal cycles. Therefore, to
reduce the reaction time and make temperature distribution uniform in
the reaction chamber, a novel oscillatory thermal cycler is designed.
The sample is placed in a fixed chamber, and three constant isothermal
zones are established and lined in the system. The sample is oscillated
and contacted with three different isothermal zones to complete
thermal cycles. This study presents the design of the geometric
characteristics of the chamber. The commercial software
CFD-ACE+TM is utilized to investigate the influences of various
materials, heating times, chamber volumes, and moving speed of the
chamber on the temperature distributions inside the chamber. The
chamber moves at a specific velocity and the boundary conditions
with time variations are related to the moving speed. Whereas the
chamber moves, the boundary is specified at the conditions of the
convection or the uniform temperature. The user subroutines compiled
by the FORTRAN language are used to make the numerical results
realistically. Results show that the reaction chamber with a rectangular
prism is heated on six faces; the effects of various moving speeds of
the chamber on the temperature distributions are examined. Regarding
to the temperature profiles and the standard deviation of the
temperature at the Y-cut cross section, the non-uniform temperature
inside chamber is found as the moving speed is larger than 0.01 m/s.
By reducing the heating faces to four, the standard deviation of the
temperature of the reaction chamber is under 1.4×10-3K with the range
of velocities between 0.0001 m/s and 1 m/s. The nature convective
boundary conditions are set at all boundaries while the chamber moves
between two heaters, the effects of various moving velocities of the
chamber on the temperature distributions are negligible at the assigned
time duration.
Abstract: Traffic enforcement units (the Police) are partly
responsible for the severity and frequency of the traffic accidents via
the effectiveness of their safety measures. The Police claims that the
reductions in accidents and their severities occur largely by their
timely interventions at the black spots, through traffic management
or temporary changes in the road design (guiding, reducing speeds
and eliminating sight obstructions, etc.). Yet, some other external
factors than the Police measures may intervene into which such
claims require a statistical confirmation. In order to test the net
impact of the Police contribution in the reduction of the number of
crashes, Chi square test was applied for 25 spots (streets and
intersections) and an average evaluation was achieved for general
conclusion in the case study of Izmir city. Separately, the net impact
of economic crisis in the reduction of crashes is assessed by the
trend analysis for the case of the economic crisis with the probable
reduction effects on the trip generation or modal choice. Finally, it
was proven that the Police measures were effective to some degree as
they claimed, though the economic crisis might have only negligible
contribution to the reductions in the same period observed.
Abstract: This paper presents a solution for ceramic cutting tools availability in interrupted machining. Experiments were performed on a special fixture – the interrupted cut simulator. This fixture was constructed at our Department of Machining and Assembly within the scope of a project by the Czech Science Foundation. The goals of the tests were to contribute to the wider usage of these cutting materials in machining, especially in interrupted machining. Through the centuries, producers of ceramic cutting tools have taken big steps forward. Namely, increasing durability in maintaining high levels of strength and hardness lends an advantage. Some producers of these materials advise cutting inserts for interrupted machining at the present time [1, 2].
Abstract: Serial Analysis of Gene Expression is a powerful
quantification technique for generating cell or tissue gene expression
data. The profile of the gene expression of cell or tissue in several
different states is difficult for biologists to analyze because of the large
number of genes typically involved. However, feature selection in
machine learning can successfully reduce this problem. The method
allows reducing the features (genes) in specific SAGE data, and
determines only relevant genes. In this study, we used a genetic
algorithm to implement feature selection, and evaluate the
classification accuracy of the selected features with the K-nearest
neighbor method. In order to validate the proposed method, we used
two SAGE data sets for testing. The results of this study conclusively
prove that the number of features of the original SAGE data set can be
significantly reduced and higher classification accuracy can be
achieved.
Abstract: Group contribution based models are widely used in
industrial applications for its convenience and flexibility. Although a
number of group contribution models have been proposed, there were
certain limitations inherent to those models. Models based on group
contribution excess Gibbs free energy are limited to low pressures and
models based on equation of state (EOS) cannot properly describe
highly nonideal mixtures including acids without introducing
additional modification such as chemical theory. In the present study
new a new approach derived from quantum chemistry have been used
to calculate necessary EOS group interaction parameters. The
COSMO-RS method, based on quantum mechanics, provides a
reliable tool for fluid phase thermodynamics. Benefits of the group
contribution EOS are the consistent extension to hydrogen-bonded
mixtures and the capability to predict polymer-solvent equilibria up to
high pressures. The authors are confident that with a sufficient
parameter matrix the performance of the lattice EOS can be improved
significantly.
Abstract: Among all mechanical joining processes, welding has
been employed for its advantage in design flexibility, cost saving,
reduced overall weight and enhanced structural performance.
However, for structures made of relatively thin components, welding
can introduce significant buckling distortion which causes loss of
dimensional control, structural integrity and increased fabrication
costs. Different parameters can affect buckling behavior of welded
thin structures such as, heat input, welding sequence, dimension of
structure. In this work, a 3-D thermo elastic-viscoplastic finite
element analysis technique is applied to evaluate the effect of shell
dimensions on buckling behavior and entropy generation of welded
thin shells. Also, in the present work, the approximated longitudinal
transient stresses which produced in each time step, is applied to the
3D-eigenvalue analysis to ratify predicted buckling time and
corresponding eigenmode. Besides, the possibility of buckling
prediction by entropy generation at each time is investigated and it is
found that one can predict time of buckling with drawing entropy
generation versus out of plane deformation. The results of finite
element analysis show that the length, span and thickness of welded
thin shells affect the number of local buckling, mode shape of global
buckling and post-buckling behavior of welded thin shells.
Abstract: If there exists a nonempty, proper subset S of the set of all (n+1)(n+2)/2 inertias such that S Ôèå i(A) is sufficient for any n×n zero-nonzero pattern A to be inertially arbitrary, then S is called a critical set of inertias for zero-nonzero patterns of order n. If no proper subset of S is a critical set, then S is called a minimal critical set of inertias. In [Kim, Olesky and Driessche, Critical sets of inertias for matrix patterns, Linear and Multilinear Algebra, 57 (3) (2009) 293-306], identifying all minimal critical sets of inertias for n×n zero-nonzero patterns with n ≥ 3 and the minimum cardinality of such a set are posed as two open questions by Kim, Olesky and Driessche. In this note, the minimum cardinality of all critical sets of inertias for 4 × 4 irreducible zero-nonzero patterns is identified.
Abstract: In order to accommodate various multimedia
services, next generation wireless networks are characterized
by very high transmission bit rates. Thus, in such systems and
networks, the received signal is not only limited by noise but -
especially with increasing symbols rate often more
significantly by the intersymbol interference (ISI) caused by
the time dispersive radio channels such as those are used in
this work. This paper deals with the study of the performance
of detector for high bit rate transmission on some worst case
models of frequency selective fading channels for outdoor
mobile radio environments. This paper deals with a number of
different wireless channels with different power profiles and
different number of resolvable paths. All the radio channels
generated in this paper are for outdoor vehicular environments
with Doppler spread of 100 Hz. A carrier frequency of 1800
MHz is used and all the channels used in this work are such
that they are useful for next generation wireless systems.
Schemes for mitigation of ISI with adaptive equalizers of
different types have been investigated and their performances
have been investigated in terms of BER measured as a function
of SNR.
Abstract: Over the past few years, a number of efforts have
been exerted to build parallel processing systems that utilize the idle
power of LAN-s and PC-s available in many homes and corporations.
The main advantage of these approaches is that they provide cheap
parallel processing environments for those who cannot afford the
expenses of supercomputers and parallel processing hardware.
However, most of the solutions provided are not very flexible in the
use of available resources and very difficult to install and setup.
In this paper, a multi-level web-based parallel processing system
(MWPS) is designed (appendix). MWPS is based on the idea of
volunteer computing, very flexible, easy to setup and easy to use.
MWPS allows three types of subscribers: simple volunteers (single
computers), super volunteers (full networks) and end users. All of
these entities are coordinated transparently through a secure web site.
Volunteer nodes provide the required processing power needed by
the system end users. There is no limit on the number of volunteer
nodes, and accordingly the system can grow indefinitely. Both
volunteer and system users must register and subscribe. Once, they
subscribe, each entity is provided with the appropriate MWPS
components. These components are very easy to install.
Super volunteer nodes are provided with special components that
make it possible to delegate some of the load to their inner nodes.
These inner nodes may also delegate some of the load to some other
lower level inner nodes .... and so on. It is the responsibility of the
parent super nodes to coordinate the delegation process and deliver
the results back to the user.
MWPS uses a simple behavior-based scheduler that takes into
consideration the current load and previous behavior of processing
nodes. Nodes that fulfill their contracts within the expected time get a
high degree of trust. Nodes that fail to satisfy their contract get a
lower degree of trust.
MWPS is based on the .NET framework and provides the minimal
level of security expected in distributed processing environments.
Users and processing nodes are fully authenticated. Communications
and messages between nodes are very secure. The system has been
implemented using C#.
MWPS may be used by any group of people or companies to
establish a parallel processing or grid environment.
Abstract: This paper sets forth the possibility and importance about applying Data Mining in Web logs mining and shows some problems in the conventional searching engines. Then it offers an improved algorithm based on the original AprioriAll algorithm which has been used in Web logs mining widely. The new algorithm adds the property of the User ID during the every step of producing the candidate set and every step of scanning the database by which to decide whether an item in the candidate set should be put into the large set which will be used to produce next candidate set. At the meantime, in order to reduce the number of the database scanning, the new algorithm, by using the property of the Apriori algorithm, limits the size of the candidate set in time whenever it is produced. Test results show the improved algorithm has a more lower complexity of time and space, better restrain noise and fit the capacity of memory.
Abstract: This paper presents a pulse doubling technique in a 12-pulse ac-dc converter which supplies direct torque controlled motor drives (DTCIMD-s) in order to have better power quality conditions at the point of common coupling. The proposed technique increases the number of rectification pulses without significant changes in the installations and yields in harmonic reduction in both ac and dc sides. The 12-pulse rectified output voltage is accomplished via two paralleled six-pulse ac-dc converters each of them consisting of three-phase diode bridge rectifier. An autotransformer is designed to supply the rectifiers. The design procedure of magnetics is in a way such that makes it suitable for retrofit applications where a six-pulse diode bridge rectifier is being utilized. Independent operation of paralleled diode-bridge rectifiers, i.e. dc-ripple re-injection methodology, requires a Zero Sequence Blocking Transformer (ZSBT). Finally, a tapped interphase reactor is connected at the output of ZSBT to double the pulse numbers of output voltage up to 24 pulses. The aforementioned structure improves power quality criteria at ac mains and makes them consistent with the IEEE-519 standard requirements for varying loads. Furthermore, near unity power factor is obtained for a wide range of DTCIMD operation. A comparison is made between 6- pulse, 12-pulse, and proposed converters from view point of power quality indices. Results show that input current total harmonic distortion (THD) is less than 5% for the proposed topology at various loads.
Abstract: Dioscorea species or commonly named as yam is
reported to be one of the major food sources worldwide. This
ethnobotanical study was conducted to document local knowledge
and potentials of DioscoreahispidaDennst. and to investigate and
record its distribution in three districts of Terengganu. Information
was gathered from 23 villagers from three districts of Besut, Marang
and Setiu by using semi-structured questionnaire. The villagers were
randomly selected and no appointment was made prior to the visits.
For distribution, the location of Dioscoreahispida was recorded by
using the Global Positioning System (GPS). The villagers identified
Dioscoreahispida or locally named ubigadong by looking at the
physical characteristics that include its leaf shape, stem and the color
of the tuber-s flesh. The villagers used Dioscoreahispida in many
ways in their life such as for food, medicinal purposes and fish
poison.
Abstract: The results show that the bridge equipped with seismic isolation bearing system shows a high amount of energy dissipation. The purpose of the present study is to analyze the overall performance of continuous curved highway viaducts with different bearing supports, with an emphasis on the effectiveness of seismic isolation based on lead rubber bearing and hedge reaction force bearing system consisted of friction sliding bearing and rubber bearing. The bridge seismic performance has been evaluated on six different cases with six bearing models. The effects of the different arrangement of bearing on the deck superstructure displacements, the seismic damage at the bottom of the piers, movement track at the pier-s top and the total and strain energies absorbed by the structure are evaluated. In conclusion, the results provide sufficient evidence of the effectiveness on the use of seismic isolation on steel curved highway bridges.
Abstract: Despite of the preponderant role played by cement among the construction materials, it is today considered as a material destructing the environment due to the large quantities of carbon dioxide exhausted during its manufacture. Besides, global warming is now recognized worldwide as the new threat to the humankind against which advanced countries are investigating measures to reduce the current amount of exhausted gases to the half by 2050. Accordingly, efforts to reduce green gases are exerted in all industrial fields. Especially, the cement industry strives to reduce the consumption of cement through the development of alkali-activated geopolymer mortars using industrial byproducts like bottom ash. This study intends to gather basic data on the flowability and strength development characteristics of alkali-activated geopolymer mortar by examining its FT-IT features with respect to the effects and strength of the alkali-activator in order to develop bottom ash-based alkali-activated geopolymer mortar. The results show that the 35:65 mass ratio of sodium hydroxide to sodium silicate is appropriate and that a molarity of 9M for sodium hydroxide is advantageous. The ratio of the alkali-activators to bottom ash is seen to have poor effect on the strength. Moreover, the FT-IR analysis reveals that larger improvement of the strength shifts the peak from 1060 cm–1 (T-O, T=Si or Al) toward shorter wavenumber.
Abstract: In general fuzzy sets are used to analyze the fuzzy
system reliability. Here intuitionistic fuzzy set theory for analyzing
the fuzzy system reliability has been used. To analyze the fuzzy
system reliability, the reliability of each component of the system as
a triangular intuitionistic fuzzy number is considered. Triangular
intuitionistic fuzzy number and their arithmetic operations are
introduced. Expressions for computing the fuzzy reliability of a
series system and a parallel system following triangular intuitionistic
fuzzy numbers have been described. Here an imprecise reliability
model of an electric network model of dark room is taken. To
compute the imprecise reliability of the above said system, reliability
of each component of the systems is represented by triangular
intuitionistic fuzzy numbers. Respective numerical example is
presented.
Abstract: The issue of leadership has been investigated from
several perspectives; however, very less from ethical perspective.
With the growing number of corporate scandals and unethical roles
played by business leaders in several parts of the world, the need to
examine leadership from ethical perspective cannot be over
emphasized. The importance of leadership credibility has been
discussed in the authentic model of leadership. Authentic leaders
display high degree of integrity, have deep sense of purpose, and
committed to their core values. As a result they promote a more
trusting relationship in their work groups that translates into several
positive outcomes. The present study examined how authentic
leadership contribute to subordinates- trust in leadership and how this
trust, in turn, predicts subordinates- work engagement. A sample of
395 employees was randomly selected from several local banks
operating in Malaysia. Standardized tools such as ALQ, OTI, and
EEQ were employed. Results indicated that authentic leadership
promoted subordinates- trust in leader, and contributed to work
engagement. Also, interpersonal trust predicted employees- work
engagement as well as mediated the relationship between this style of
leadership and employees- work engagement.
Abstract: The influence of physical (external added weight) and
neurophysiological (fatigue) factors on static and dynamic balance in
sport related activities was typified statically by the Romberg test
(one foot flat, eyes open) and dynamically by jumping and hopping
in both horizontal and vertical directions. Twenty healthy males were
participated in this study. In Static condition, added weight increased
body-s inertia and therefore decreased body sway in AP direction
though not significantly. Dynamically, added weight significantly
increased body sway in both ML and AP directions, indicating
instability, and the use of the counter rotating segments mechanism to
maintain balance was demonstrated. Fatigue on the other hand
significantly increased body sway during static balance as a
neurophysiological adaptation primarily to the inverted pendulum
mechanism. Dynamically, fatigue significantly increased body sway
in both ML and AP directions again indicating instability but with a
greater use of counter rotating segments mechanism. Differential
adaptations for each of the two balance mechanisms (inverted
pendulum and counter rotating segments) were found between one
foot flat and two feet flat dynamic conditions, as participants relied
more heavily on the first in the one foot flat conditions and relied
more on the second in the two feet flat conditions.