Abstract: The fixed partial dentures are mainly used in the frontal
part of the dental arch because of their great esthetics. There are
several factors that are associated with the stress state created in
ceramic restorations, including: thickness of ceramic layers,
mechanical properties of the materials, elastic modulus of the
supporting substrate material, direction, magnitude and frequency of
applied load, size and location of occlusal contact areas, residual
stresses induced by processing or pores, restoration-cement
interfacial defects and environmental defects. The purpose of this
study is to evaluate the capability of Polarization Sensitive Optical
Coherence Tomography (PSOCT) in detection and analysis of
possible material defects in metal-ceramic and integral ceramic fixed
partial dentures. As a conclusion, it is important to have a non
invasive method to investigate fixed partial prostheses before their
insertion in the oral cavity in order to satisfy the high stress
requirements and the esthetic function.
Abstract: Discrimination between different classes of environmental
sounds is the goal of our work. The use of a sound recognition
system can offer concrete potentialities for surveillance and
security applications. The first paper contribution to this research
field is represented by a thorough investigation of the applicability
of state-of-the-art audio features in the domain of environmental
sound recognition. Additionally, a set of novel features obtained by
combining the basic parameters is introduced. The quality of the
features investigated is evaluated by a HMM-based classifier to which
a great interest was done. In fact, we propose to use a Multi-Style
training system based on HMMs: one recognizer is trained on a
database including different levels of background noises and is used
as a universal recognizer for every environment. In order to enhance
the system robustness by reducing the environmental variability, we
explore different adaptation algorithms including Maximum Likelihood
Linear Regression (MLLR), Maximum A Posteriori (MAP)
and the MAP/MLLR algorithm that combines MAP and MLLR.
Experimental evaluation shows that a rather good recognition rate
can be reached, even under important noise degradation conditions
when the system is fed by the convenient set of features.
Abstract: Previous studies on political budget cycles (PBCs)
implicitly assume the executive has full discretion power over fiscal
policy, neglecting the role of checks and balances of the legislature.
This paper goes beyond traditional PBCs models and sheds light on
the case study of Japan, South Korea, and Taiwan over the 1988-2007
periods. Based on the results, we find no evidence of electoral impacts
on the public expenditures in South Korean and Taiwan's
congressional elections. We also noted that PBCs are found on
Taiwan-s government expenditures during our sample periods.
Furthermore, the results also show that Japan-s legislature has a
significant checks and balances on government-s expenditures.
However, empirical results show that the legislature veto player in
Taiwan neither has effect on the reduction of public expenditures, nor
has the moderating effect over Taiwan-s political budget cycles, albeit
that they are statistically insignificant.We suggest that the existence of
PBCs in Taiwan is due to a weaker systemof checks and balances. Our
conjecture is that Taiwan either has no legislative veto player or has
observed low compliance to the law during the time period examined
in our study.
Abstract: This paper presents a study on the thermodynamics
and transport properties of hot potassium carbonate aqueous system
(HPC) using electrolyte non-random two liquid, (ELECNRTL)
model. The operation conditions are varied to determine the system
liquid phase stability range at the standard and critical conditions. A
case study involving 30 wt% K2CO3, H2O standard system at
pressure of 1 bar and temperature range from 280.15 to 366.15 K has
been studied. The estimated solubility index, viscosity, water
activity, and density which obtained from the simulation showed a
good agreement with the experimental work. Furthermore, the
saturation temperature of the solution has been estimated.
Abstract: In order to maximize efficiency of an information management platform and to assist in decision making, the collection, storage and analysis of performance-relevant data has become of fundamental importance. This paper addresses the merits and drawbacks provided by the OLAP paradigm for efficiently navigating large volumes of performance measurement data hierarchically. The system managers or database administrators navigate through adequately (re)structured measurement data aiming to detect performance bottlenecks, identify causes for performance problems or assessing the impact of configuration changes on the system and its representative metrics. Of particular importance is finding the root cause of an imminent problem, threatening availability and performance of an information system. Leveraging OLAP techniques, in contrast to traditional static reporting, this is supposed to be accomplished within moderate amount of time and little processing complexity. It is shown how OLAP techniques can help improve understandability and manageability of measurement data and, hence, improve the whole Performance Analysis process.
Abstract: Atherosclerosis was identified as a chronic inflammatory process resulting from interactions between plasma lipoproteins, cellular components (monocyte, macrophages, T lymphocytes, endothelial cells and smooth muscle cells) and the extracellular matrix of the arterial wall. Several types of genes were known to express during formation of atherosclerosis. This study is carried out to identify unknown differentially expressed gene (DEG) in atherogenesis. Rabbit’s aorta tissues were stained by H&E for histomorphology. GeneFishing™ PCR analysis was performed from total RNA extracted from the aorta tissues. The DNA fragment from DEG was cloned, sequenced and validated by Real-time PCR. Histomorphology showed intimal thickening in the aorta. DEG detected from ACP-41 was identified as cathepsin B gene and showed upregulation at week-8 and week-12 of atherogenesis. Therefore, ACP-based GeneFishing™ PCR facilitated identification of cathepsin B gene which was differentially expressed during development of atherosclerosis.
Abstract: Human genome is not only the evolutionary
summation of all advantageous events, but also houses lesions of
deleterious foot prints. A single gene mutation sometimes may
express multiple consequences in numerous tissues and a linear
relationship of the genotype and the phenotype may often be obscure.
ß Thalassemia minor, a transfusion independent mild anaemia,
coupled with environment among other factors may articulate into
phenotypic pleotropy with Hypocholesterolemia, Vitamin D
deficiency, Tissue hypoxia, Hyper-parathyroidism and Psychological
alterations. Occurrence of Pancreatic insufficiency, resultant
steatorrhoea, Vitamin-D (25-OH) deficiency (13.86 ngm/ml) with
Hypocholesterolemia (85mg/dl) in a 30 years old male ß Thal-minor
patient (Hemoglobin 11mg/dl with Fetal Hemoglobin 2.10%, Hb A2
4.60% and Hb Adult 84.80% and altered Hemogram) with increased
Para thyroid hormone (62 pg/ml) & moderate Serum Ca+2
(9.5mg/ml) indicate towards a cascade of phenotypic pleotropy
where the ß Thalassemia mutation ,be it in the 5’ cap site of the
mRNA , differential splicing etc in heterozygous state is effecting
several metabolic pathways. Compensatory extramedulary
hematopoiesis may not coped up well with the stressful life style of
the young individual and increased erythropoietic stress with high
demand for cholesterol for RBC membrane synthesis may have
resulted in Hypocholesterolemia.Oxidative stress and tissue hypoxia
may have caused the pancreatic insufficiency, leading to Vitamin D
deficiency. This may in turn have caused the secondary
hyperparathyroidism to sustain serum Calcium level. Irritability and
stress intolerance of the patient was a cumulative effect of the vicious
cycle of metabolic compromises. From these findings we propose
that the metabolic deficiencies in the ß Thalassemia mutations may
be considered as the phenotypic display of the pleotropy to explain
the genetic epidemiology.
According to the recommendations from the NIH Workshop on
Gene-Environment Interplay in Common Complex Diseases: Forging
an Integrative Model, study design of observations should be
informed by gene-environment hypotheses and results of a study
(genetic diseases) should be published to inform future hypotheses.
Variety of approaches is needed to capture data on all possible
aspects, each of which is likely to contribute to the etiology of
disease. Speakers also agreed that there is a need for development of
new statistical methods and measurement tools to appraise
information that may be missed out by conventional method where
large sample size is needed to segregate considerable effect.
A meta analytic cohort study in future may bring about significant
insight on to the title comment.
Abstract: In the upstream we place a piece of ring and rotate
it with 83Hz, 166Hz, 333Hz,and 666H to find the effect of the
periodic distortion.In the experiment this type of the perturbation
will not allow since the mechanical failure of any parts of the
equipment in the upstream will destroy the blade system. This type of
study will be only possible by CFD. We use two pumps NS32
(ENSAM) and three blades pump (Tamagawa Univ). The benchmark
computations were performed without perturbation parts, and confirm
the computational results well agreement in head-flow rate. We
obtained the pressure fluctuation growth rate that is representing the
global instability of the turbo-system. The fluctuating torque
components were 0.01Nm(5000rpm), 0.1Nm(10000rmp),
0.04Nm(20000rmp), 0.15Nm( 40000rmp) respectively. Only for
10000rpm(166Hz) the output toque was random, and it implies that it
creates unsteady flow by separations on the blades, and will reduce the
pressure loss significantly
Abstract: Leave of absence is important in maintaining a good
status of human resource quality. Allowing the employees temporarily
free from the routine assignments can vitalize the workers- morality
and productivity. This is particularly critical to secure a satisfactory
service quality for healthcare professionals of which were typically
featured with labor intensive and complicated works to perform. As
one of the veteran hospitals that were found and operated by the
Veteran Department of Taiwan, the nursing staff of the case hospital
was squeezed to an extreme minimum level under the pressure of a
tight budgeting. Leave of absence on schedule became extremely
difficult, especially for the intensive care units (ICU), in which
required close monitoring over the cared patients, and that had more
easily driven the ICU nurses nervous. Even worse, the deferred leaves
were more than 10 days at any time in the ICU because of a fluctuating
occupancy. As a result, these had brought a bad setback to this
particular nursing team, and consequently defeated the job
performance and service quality. To solve this problem and
accordingly to strengthen their morality, a project team was organized
across different departments specific for this. Sufficient information
regarding jobs and positions requirements, labor resources, and actual
working hours in detail were collected and analyzed in the team
meetings. Several alternatives were finalized. These included job
rotating, job combination, leave on impromptu and cross-departmental
redeployment. Consequently, the deferred leave days sharply reduced
70% to a level of 3 or less days. This improvement had not only
provided good shelter for the ICU nurses that improved their job
performance and patient safety but also encouraged the nurses active
participating of a project and learned the skills of solving problems
with colleagues.
Abstract: Since the beginning of human history, human
activities have caused many changes in the environment. Today, a
particular attention should be paid to gaining knowledge about water
quality of wetlands which are pristine natural environments rich in
genetic reserves. If qualitative conditions of industrial areas (in terms
of both physicochemical and biological conditions) are not addressed
properly, they could cause disruption in natural ecosystems,
especially in rivers. With regards to the quality of water resources,
determination of pollutant sources plays a pivotal role in engineering
projects as well as designing water quality control systems. Thus,
using different methods such as flow duration curves, dischargepollution
load model and frequency analysis by HYFA software
package, risk of various industrial pollutants in international and
ecologically important Gavkhoni wetland is analyzed. In this study, a
station located at Varzaneh City is used as the last station on
Zayanderud River, from where the river water is discharged into the
wetland. Results showed that elements- concentrations often
exceeded the allowed level and river water can endanger regional
ecosystem. In addition, if the river discharge is managed on Q25
basis, this basis can lower concentrations of elements, keeping them
within the normal level.
Abstract: Solution to unsteady Navier-Stokes equation by Splitting method in physical orthogonal algebraic curvilinear coordinate system, also termed 'Non-linear grid system' is presented. The linear terms in Navier-Stokes equation are solved by Crank- Nicholson method while the non-linear term is solved by the second order Adams-Bashforth method. This work is meant to bring together the advantage of Splitting method as pressure-velocity solver of higher efficiency with the advantage of consuming Non-linear grid system which produce more accurate results in relatively equal number of grid points as compared to Cartesian grid. The validation of Splitting method as a solution of Navier-Stokes equation in Nonlinear grid system is done by comparison with the benchmark results for lid driven cavity flow by Ghia and some case studies including Backward Facing Step Flow Problem.
Abstract: Through a proper analysis of residual strain and stress
distributions obtained at the surface of high speed milled specimens
of AA 6082–T6 aluminium alloy, the performance of an improved
indentation method is evaluated. This method integrates a special
device of indentation to a universal measuring machine. The
mentioned device allows introducing elongated indents allowing to
diminish the absolute error of measurement. It must be noted that the
present method offers the great advantage of avoiding both the
specific equipment and highly qualified personnel, and their inherent
high costs. In this work, the cutting tool geometry and high speed
parameters are selected to introduce reduced plastic damage.
Through the variation of the depth of cut, the stability of the shapes
adopted by the residual strain and stress distributions is evaluated.
The results show that the strain and stress distributions remain
unchanged, compressive and small. Moreover, these distributions
reveal a similar asymmetry when the gradients corresponding to
conventional and climb cutting zones are compared.
Abstract: This study was designed to investigate the role of serum nitric oxide and sialic acid in the development of diabetic nephropathy as disease marker. Total 210 diabetic patients (age and sex matched) were selected followed by informed consent and divided into four groups (70 each) as I: control; II: diabetic; III: diabetic hypertensive; IV: diabetic nephropathy. The blood samples of all subjects were collected and analyzed for serum nitric oxide, sialic acid, fasting blood glucose, serum urea, creatinine, HbA1c and GFR. The BMI, systolic and diastolic blood pressures, blood glucose, HbA1c and serum sialic acid levels were high (p
Abstract: The fractal-shaped orifices are assumed to have a
significant effect on the pressure drop downstream pipe flow due to
their edge self-similarity shape which enhances the mixing
properties. Here, we investigate the pressure drop after these fractals
using a digital micro-manometer at different stations downstream a
turbulent flow pipe then a direct comparison has been made with the
pressure drop measured from regular orifices with the same flow
area. Our results showed that the fractal-shaped orifices have a
significant effect on the pressure drop downstream the flow. Also
the pressure drop measured across the fractal-shaped orifices is
noticed to be lower that that from ordinary orifices of the same flow
areas. This result could be important in designing piping systems
from point of view of losses consideration with the same flow
control area. This is promising to use the fractal-shaped orifices as
flowmeters as they can sense the pressure drop across them
accurately with minimum losses than the regular ones.
Abstract: Two-phase frictional pressure drop data were
obtained for condensation of carbon dioxide in single horizontal
micro tube of inner diameter ranged from 0.6 mm up to 1.6 mm over
mass flow rates from 2.5*10-5 to 17*10-5 kg/s and vapor qualities
from 0.0 to 1.0. The inlet condensing pressure is changed from 33.5
to 45 bars. The saturation temperature ranged from -1.5 oC up to 10
oC. These data have then been compared against three (two-phase)
frictional pressure drop prediction methods. The first method is by
Muller-Steinhagen and Heck (Muller-Steinhagen H, Heck K. A
simple friction pressure drop correlation for two-phase flow in pipes.
Chem. Eng. Process 1986;20:297–308) and that by Gronnerud R.
Investigation of liquid hold-up, flow-resistance and heat transfer in
circulation type evaporators, part IV: two-phase flow resistance in
boiling refrigerants, Annexe 1972. Then the method used by
FriedelL. Improved friction pressures drop in horizontal and vertical
two-phase pipe flow. European Two-Phase Flow Group Meeting,
Paper E2; 1979 June, Ispra, Italy. The methods are used by M.B Ould
Didi et al (2001) “Prediction of two-phase pressure gradients of
refrigerant in horizontal tubes". Int.J.of Refrigeration 25(2002) 935-
947. The best available method for annular flow was that of Muller-
Steinhagen and Heck. It was observed that the peak in the two-phase
frictional pressure gradient is at high vapor qualities.
Abstract: The aim of this paper is to present current and future
procedures in castings procurement. Differences in procurement are
highlighted. The supplier selection criteria used in practice is
compared to literature findings. Different trends related to supply
chains are presented and it is described how they are reflected in
reality to castings procurement. To fulfil the aim, interviews were
conducted in nine companies using castings. It was found that largest
casting users have the most subcontractor foundries and it is more
typical that they have multiple suppliers for the same parts. Currently
only two companies out of nine purchase castings outside Europe,
but the others are also progressing in the same direction. The main
reason is the need to lower purchasing costs. Another trend is that all
companies want to buy cast components or sub-assemblies instead of
raw castings from foundries. It was found that price is a main
supplier selection criterion. All companies use competitive bidding in
supplier selection.
Abstract: This paper explores the scalability issues associated
with solving the Named Entity Recognition (NER) problem using
Support Vector Machines (SVM) and high-dimensional features. The
performance results of a set of experiments conducted using binary
and multi-class SVM with increasing training data sizes are
examined. The NER domain chosen for these experiments is the
biomedical publications domain, especially selected due to its
importance and inherent challenges. A simple machine learning
approach is used that eliminates prior language knowledge such as
part-of-speech or noun phrase tagging thereby allowing for its
applicability across languages. No domain-specific knowledge is
included. The accuracy measures achieved are comparable to those
obtained using more complex approaches, which constitutes a
motivation to investigate ways to improve the scalability of multiclass
SVM in order to make the solution more practical and useable.
Improving training time of multi-class SVM would make support
vector machines a more viable and practical machine learning
solution for real-world problems with large datasets. An initial
prototype results in great improvement of the training time at the
expense of memory requirements.
Abstract: The shortest path routing problem is a multiobjective nonlinear optimization problem with constraints. This problem has been addressed by considering Quality of service parameters, delay and cost objectives separately or as a weighted sum of both objectives. Multiobjective evolutionary algorithms can find multiple pareto-optimal solutions in one single run and this ability makes them attractive for solving problems with multiple and conflicting objectives. This paper uses an elitist multiobjective evolutionary algorithm based on the Non-dominated Sorting Genetic Algorithm (NSGA), for solving the dynamic shortest path routing problem in computer networks. A priority-based encoding scheme is proposed for population initialization. Elitism ensures that the best solution does not deteriorate in the next generations. Results for a sample test network have been presented to demonstrate the capabilities of the proposed approach to generate well-distributed pareto-optimal solutions of dynamic routing problem in one single run. The results obtained by NSGA are compared with single objective weighting factor method for which Genetic Algorithm (GA) was applied.
Abstract: In this study, the adhesion of ice to solid substrates
with different surface properties is compared. Clear ice, similar to
atmospheric in-flight icing encounters, is accreted on the different
substrates under controlled conditions. The ice adhesion behavior is
investigated by means of a dynamic vibration testing technique with
an electromagnetic shaker initiating ice de-bonding in the interface
between the substrate and the ice. The results of the experiments
reveal that the affinity for ice accretion is significantly influenced by
the water contact angle of the respective sample.
Abstract: Anti-allergic effects of royal jelly were evaluated in a human-like mouse model of atopic dermatitis. NC/Nga mice were cutaneously applied with royal jelly for 6 weeks. Royal jelly-treated mice exhibited lower levels of serum total immunoglobulin E in comparison with controls. We found that the treatment decreased (11% to the control) expression of mRNA for aquaporin-3, which is involved in the modulation of epidermal hydration. Microarray analysis revealed more than 10-fold changes in the expression of several genes, such as transglutaminase 2, repetin, and keratins. In normal human epidermal keratinocytes, royal jelly extract suppressed interleukin-8 elevation induced by TNF-α and interferon-γ, suggesting direct anti-inflammatory activity in keratinocytes. Collectively, topical application of royal jelly may be useful for amelioration of lesions and inflammation in atopic dermatitis.