Effect of Oral Administration of “Gadagi“ Tea on Liver Function in Rats

Effect of oral administration of “Gadagi" tea on liver function was assessed on 50 healthy male albino rats which were grouped and administered with different doses(mg/kg) i.e low dose (380mg/kg, 415mg/kg, 365mg/kg, 315mg/kg for “sak", “sada" and “magani" respectively), standard dose ( 760mg/kg, 830mg/kg, 730mg/kg for “sak-, “sada" and “magani" respectively) and high dose (1500mg/kg, 1700mg/kg and 1460mg/kg for “sak--,"sada" and “magani" groups respectively) for a period of four weeks. Animals that were not administered with the tea constituted the control group. At the end of fourth week, the animals were sacrificed and their serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), total protein (TP), albumin (ALB), and globulins (GLO) were determined. Mean serum ALT and ALP activities were significantly higher (P

Principal Type of Water Responsible for Damage of Concrete Repeated Freeze-Thaw Cycles

The first and basic cause of the failure of concrete is repeated freezing (thawing) of moisture contained in the pores, microcracks, and cavities of the concrete. On transition to ice, water existing in the free state in cracks increases in volume, expanding the recess in which freezing occurs. A reduction in strength below the initial value is to be expected and further cycle of freezing and thawing have a further marked effect. By using some experimental parameters like nuclear magnetic resonance variation (NMR), enthalpy-temperature (or heat capacity) variation, we can resolve between the various water states and their effect on concrete properties during cooling through the freezing transition temperature range. The main objective of this paper is to describe the principal type of water responsible for the reduction in strength and structural damage (frost damage) of concrete following repeated freeze –thaw cycles. Some experimental work was carried out at the institute of cryogenics to determine what happens to water in concrete during the freezing transition. 

Swelling Behavior and Cytotoxicity of Maleic Acid Grafted Chitosan

Chitosan is an attractive polysaccharide obtained by deacetylation of an abundant natural biopolymer called chitin. Chitin and chitosan are excellent materials. To improve the potential of chitin and chitosan modification is needed. In the present study, grafting of maleic acid on to chitosan by cerium ammonium nitrate in acetic acid solution was investigated with use of a microwave and reflux system. The grafted chitosan was characterized by using a Fourier-transform infrared spectrometry. The solubility and swelling behavior of grafted chitosans were determined in acetate buffer (pH 3.6), citrophosphate buffer (pH 5.6 and pH 7.0), and boric buffer (pH 9.2) solutions. The sample obtained by microwave system with use of a chitosan/maleic anhydride/ceric ammonium nitrate 0.2/3.922/0.99 gram of raw material within 30 minute showed the maximum swelling ratio (13.6) in boric buffer solution.

Target Detection using Adaptive Progressive Thresholding Based Shifted Phase-Encoded Fringe-Adjusted Joint Transform Correlator

A new target detection technique is presented in this paper for the identification of small boats in coastal surveillance. The proposed technique employs an adaptive progressive thresholding (APT) scheme to first process the given input scene to separate any objects present in the scene from the background. The preprocessing step results in an image having only the foreground objects, such as boats, trees and other cluttered regions, and hence reduces the search region for the correlation step significantly. The processed image is then fed to the shifted phase-encoded fringe-adjusted joint transform correlator (SPFJTC) technique which produces single and delta-like correlation peak for a potential target present in the input scene. A post-processing step involves using a peak-to-clutter ratio (PCR) to determine whether the boat in the input scene is authorized or unauthorized. Simulation results are presented to show that the proposed technique can successfully determine the presence of an authorized boat and identify any intruding boat present in the given input scene.

Pro-inflammatory Phenotype of COPD Fibroblasts not Compatible with Repair in COPD Lung

COPD is characterized by loss of elastic fibers from small airways and alveolar walls, with the decrease in elastin increasing with disease severity. It is unclear why there is a lack of repair of elastic fibers. We have examined fibroblasts cultured from lung tissue from normal and COPD subjects to determine if the secretory profile explains lack of tissue repair. In this study, fibroblasts were cultured from lung parenchyma of bronchial carcinoma patients with varying degrees of COPD; controls (non-COPD, n=5), mild COPD (GOLD 1, n=5) and moderate-severe COPD (GOLD 2-3, n=12). Measurements were made of proliferation, senescence-associated beta-galactosidase-1, mRNA expression of IL-6, IL-8, MMP-1, tropoelastin and versican, and protein levels for IL-6, IL-8, PGE2, tropoelastin, insoluble elastin, and versican. It was found that GOLD 2-3 fibroblasts proliferated more slowly (p

Rheological Properties of Polyethylene and Polypropylene Modified Bitumen

This paper presents a part of research on the rheological properties of bitumen modified by thermoplastic namely linear low density polyethylene (LLDPE), high density polyethylene (HDPE) and polypropylene (PP) and its interaction with 80 pen base bitumen. As it is known that the modification of bitumen by the use of polymers enhances its performance characteristics but at the same time significantly alters its rheological properties. The rheological study of polymer modified bitumen (PMB) was made through penetration, ring & ball softening point and viscosity test. The results were then related to the changes in the rheological properties of polymer modified bitumen. It was observed that thermoplastic copolymer shows profound effect on penetration rather than softening point. The viscoelastic behavior of polymer modified bitumen depend on the concentration of polymer, mixing temperature, mixing technique, solvating power of base bitumen and molecular structure of polymer used. PP offer better blend in comparison to HDPE and LLDPE. The viscosity of base bitumen was also enhanced with the addition of polymer. The pseudoplastic behavior was more prominent for HDPE and LLDPE than PP. Best results were obtained when polymer concentration was kept below 3%

HOPF Bifurcation of a Predator-prey Model with Time Delay and Habitat Complexity

In this paper, a predator-prey model with time delay and habitat complexity is investigated. By analyzing the characteristic equations, the local stability of each feasible equilibria of the system is discussed and the existence of a Hopf bifurcation at the coexistence equilibrium is established. By choosing the sum of two delays as a bifurcation parameter, we show that Hopf bifurcations can occur as  crosses some critical values. By deriving the equation describing the flow on the center manifold, we can determine the direction of the Hopf bifurcations and the stability of the bifurcating periodic solutions. Numerical simulations are carried out to illustrate the main theoretical results.

Bioleaching of Heavy Metals from Sewage Sludge Using Indigenous Iron-Oxidizing Microorganisms: Effect of Substrate Concentration and Total Solids

In the present study, the effect of ferrous sulfate concentration and total solids on bioleaching of heavy metals from sewage sludge has been examined using indigenous iron-oxidizing microorganisms. The experiments on effects of ferrous sulfate concentrations on bioleaching were carried out using ferrous sulfate of different concentrations (5-20 g L-1) to optimize the concentration of ferrous sulfate for maximum bioleaching. A rapid change in the pH and ORP took place in first 2 days followed by a slow change till 16th day in all the sludge samples. A 10 g L-1 ferrous sulfate concentration was found to be sufficient in metal bioleaching in the following order: Zn: 69%>Cu: 52%>Cr: 46%>Ni: 45. Further, bioleaching using 10 g/L ferrous sulfate was found to be efficient up to 20 g L-1 sludge solids concentration. The results of the present study strongly indicate that using 10 g L-1 ferrous sulfate indigenous iron-oxidizing microorganisms can bring down pH to a value needed for significant metal solubilization.

Examination of Pre-Tender Budgeting Techniques for Mechanical and Electrical Services in Malaysia

The procurement and cost management approach adopted for mechanical and electrical (M&E) services in Malaysian construction industry have been criticized for its inefficiency. The study examined early cost estimating practices adopted for mechanical and electrical services (M&E) in Malaysia so as to understand the level of compliance of the current techniques with best practices. The methodology adopted for the study is a review of bidding documents used on both completed and on – going building projects awarded between 2008 – 2010 under 9th Malaysian Plan. The analysis revealed that, M&E services cost cannot be reliably estimated at pre-contract stage; the bidding techniques adopted for M&E services failed to provide uniform basis for contractors to submit tender; detailed measurement of items were not made which could complicate post contract cost control and financial management. The paper concluded that, there is need to follow a structured approach in determining the pre-contract cost estimate for M&E services which will serve as a virile tool for post contract cost control.

Role of Oxidative DNA Damage in Pathogenesis of Diabetic Neuropathy

Oxidative stress is considered to be the cause for onset and the progression of type 2 diabetes mellitus (T2DM) and complications including neuropathy. It is a deleterious process that can be an important mediator of damage to cell structures: protein, lipids and DNA. Data suggest that in patients with diabetes and diabetic neuropathy DNA repair is impaired, which prevents effective removal of lesions. Objective: The aim of our study was to evaluate the association of the hOGG1 (326 Ser/Cys) and XRCC1 (194 Arg/Trp, 399 Arg/Gln) gene polymorphisms whose protein is involved in the BER pathway with DNA repair efficiency in patients with diabetes type 2 and diabetic neuropathy compared to the healthy subjects. Genotypes were determined by PCR-RFLP analysis in 385 subjects, including 117 with type 2 diabetes, 56 with diabetic neuropathy and 212 with normal glucose metabolism. The polymorphisms studied include codon 326 of hOGG1 and 194, 399 of XRCC1 in the base excision repair (BER) genes. Comet assay was carried out using peripheral blood lymphocytes from the patients and controls. This test enabled the evaluation of DNA damage in cells exposed to hydrogen peroxide alone and in the combination with the endonuclease III (Nth). The results of the analysis of polymorphism were statistically examination by calculating the odds ratio (OR) and their 95% confidence intervals (95% CI) using the ¤ç2-tests. Our data indicate that patients with diabetes mellitus type 2 (including those with neuropathy) had higher frequencies of the XRCC1 399Arg/Gln polymorphism in homozygote (GG) (OR: 1.85 [95% CI: 1.07-3.22], P=0.3) and also increased frequency of 399Gln (G) allele (OR: 1.38 [95% CI: 1.03-1.83], P=0.3). No relation to other polymorphisms with increased risk of diabetes or diabetic neuropathy. In T2DM patients complicated by neuropathy, there was less efficient repair of oxidative DNA damage induced by hydrogen peroxide in both the presence and absence of the Nth enzyme. The results of our study suggest that the XRCC1 399 Arg/Gln polymorphism is a significant risk factor of T2DM in Polish population. Obtained data suggest a decreased efficiency of DNA repair in cells from patients with diabetes and neuropathy may be associated with oxidative stress. Additionally, patients with neuropathy are characterized by even greater sensitivity to oxidative damage than patients with diabetes, which suggests participation of free radicals in the pathogenesis of neuropathy.

A Review of Enterprise Risk Management Practices among Malaysian Public Listed Companies

The risk sphere in business is fast changing and expanding. Almost anything has become a risk factor that will have potent, direct, and far reaching impacts on business. This paper examines the intensity of enterprise risk management (ERM) practices among the Malaysian public listed companies. The paper espouses a ERM framework comprising fourteen important implementation elements and processes. Results of the analysis indicate that the intensity of ERM implementation among the respondents is in the ‘good’ category of the semantic scale, which is deemed encouraging vis-à-vis the country’s regulatory regime.

Concentrated Solar Power Utilization in Space Vehicles Propulsion and Power Generation

The objective from this paper is to design a solar thermal engine for space vehicles orbital control and electricity generation. A computational model is developed for the prediction of the solar thermal engine performance for different design parameters and conditions in order to enhance the engine efficiency. The engine is divided into two main subsystems. First, the concentrator dish which receives solar energy from the sun and reflects them to the cavity receiver. The second one is the cavity receiver which receives the heat flux reflected from the concentrator and transfers heat to the fluid passing over. Other subsystems depend on the application required from the engine. For thrust application, a nozzle is introduced to the system for the fluid to expand and produce thrust. Hydrogen is preferred as a working fluid in the thruster application. Results model developed is used to determine the thrust for a concentrator dish 4 meters in diameter (provides 10 kW of energy), focusing solar energy to a 10 cm aperture diameter cavity receiver. The cavity receiver outer length is 50 cm and the internal cavity is 47 cm in length. The suggested design material of the internal cavity is tungsten to withstand high temperature. The thermal model and analysis shows that the hydrogen temperature at the plenum reaches 2000oK after about 250 seconds for hot start operation for a flow rate of 0.1 g/sec.Using solar thermal engine as an electricity generation device on earth is also discussed. In this case a compressor and turbine are used to convert the heat gained by the working fluid (air) into mechanical power. This mechanical power can be converted into electrical power by using a generator.

Wavelet Based Qualitative Assessment of Femur Bone Strength Using Radiographic Imaging

In this work, the primary compressive strength components of human femur trabecular bone are qualitatively assessed using image processing and wavelet analysis. The Primary Compressive (PC) component in planar radiographic femur trabecular images (N=50) is delineated by semi-automatic image processing procedure. Auto threshold binarization algorithm is employed to recognize the presence of mineralization in the digitized images. The qualitative parameters such as apparent mineralization and total area associated with the PC region are derived for normal and abnormal images.The two-dimensional discrete wavelet transforms are utilized to obtain appropriate features that quantify texture changes in medical images .The normal and abnormal samples of the human femur are comprehensively analyzed using Harr wavelet.The six statistical parameters such as mean, median, mode, standard deviation, mean absolute deviation and median absolute deviation are derived at level 4 decomposition for both approximation and horizontal wavelet coefficients. The correlation coefficient of various wavelet derived parameters with normal and abnormal for both approximated and horizontal coefficients are estimated. It is seen that in almost all cases the abnormal show higher degree of correlation than normals. Further the parameters derived from approximation coefficient show more correlation than those derived from the horizontal coefficients. The parameters mean and median computed at the output of level 4 Harr wavelet channel was found to be a useful predictor to delineate the normal and the abnormal groups.

The Rise of Nationalism among South Korean Youth and Democracy: An Analysis

The 2008 Candlelight Protests of Korea was very significant to portray the political environment among the South Korean youth. Many challenges and new advanced technologies have driven the youth community to be engaged in the political arena that has shifted them from traditional Korean youth to a very greater community. Due to historical perspective with the people of North Korea, the young generation has embraced different view of ethnic nationalism. This study examines the youth involvement in politics in line with their level of acceptance the practice of democracy. The increase usage of new media has shown great results in the survey results whereby the youth used as a platform to gain political information and brought higher degree of their sociopolitical interests among them. Furthermore, the rise of nationalism and patriotism will be discussed in this paper to the dynamism of the political approaches used by the Korea government

Methodology of Restoration Research in Czech Republic

Restoration research has become important on principle recently in Czech Republic. The reason is simple. More than 70 % of mined brown coal comes from the North Bohemian Basin these days. Open cast brown coal mining has lead to large damage on the landscape. Reclamation of phytotoxic areas is one of the serious problems in the North Bohemian Basin. It mainly concerns the areas with the occurrence of overburden rocks from the coal bed enriched with coal. The presented paper includes the characteristics of the important phytotoxic areas and the methodology of their reclamation. The results are documented with the long term monitoring of physical, mineralogical, chemical and pedological parameters of rocks in the testing areas.

Relational Impact of Job Stress on Gender Based Managerial Effectiveness in Ghanaian Organizations

This study explored the relationship between occupational stress and the perceived effectiveness of men and women managers in Ghanaian organizations. The exploration is underlined by attempt to understand the degree to which male and female managers in Ghanaian organizations experience occupational stress at the workplace. The purpose is to examine the sources and extents of occupational stress experienced by male and female managers in Ghana. Data was collected using questionnaires and analyzed using both descriptive statistics and correlation analysis. The results showed that female managers in Ghana are more likely to report of more stress experiences in the workplace than their male counterparts. The female managers are more likely to perceive role conflict and alienation as job stressors while the male managers perceived blocked career as a major source of workplace stress. It is concluded that despite the female managers experiencing enormous level of occupational stress, there was no significant differences between their managerial effectiveness and that of the male.

Enhanced Coagulation of Disinfection By-Products Precursors in Porsuk Water Resource, Eskisehir

Natural organic matter (NOM) is heterogeneous mixture of organic compounds that enter the water media from animal and plant remains, domestic and industrial wastes. Researches showed that NOM is likely precursor material for disinfection by products (DBPs). Chlorine very commenly used for disinfection purposes and NOM and chlorine reacts then Trihalomethane (THM) and Haloacetic acids (HAAs) which are cancerogenics for human health are produced. The aim of the study is to search NOM removal by enhanced coagulation from drinking water source of Eskisehir which is supplied from Porsuk Dam. Recently, Porsuk dam water is getting highly polluted and therefore NOM concentration is increasing. Enhanced coagulation studies were evaluated by measurement of Dissolved Organic Carbon (DOC), UV absorbance at 254 nm (UV254), and different trihalomethane formation potential (THMFP) tests. Results of jar test experiments showed that NOM can be removed from water about 40-50 % of efficiency by enhanced coagulation. Optimum coagulant type and coagulant dosages were determined using FeCl3 and Alum.

Rare Earth Elements in Soils of Jharia Coal Field

There are many sources trough which the soil get enriched and contaminated with REEs. The determination of REEs in environmental samples has been limited because of the lack of sensitive analytical techniques. Soil samples were collected from four sites including open cast coal mine, natural coal burning, coal washery and control in the coal field located in Dhanbad, India. Total concentrations of rare earth elements (REEs) were determined using the inductively coupled plasma atomic absorption spectrometry in order to assess enrichment status in the coal field. Results showed that the mean concentrations of La, Pr, Eu, Tb, Ho, and Tm in open cast mine and natural coal burning sites were elevated compared to the reference concentrations, while Ce, Nd, Sm, and Gd were elevated in coal washery site. When compared to reference soil, heavy REEs (HREEs) were enriched in open cast mines and natural coal burning affected soils, however, the HREEs were depleted in the coal washery sites. But, the Chondrite-normalization diagram showed significant enrichment for light REEs (LREEs) in all the soils. High concentration of Pr, Eu, Tb, Ho, Tm, and Lu in coal mining and coal burning sites may pose human health risks. Factor analysis showed that distribution and relative abundance of REEs of the coal washery site is comparable with the control. Eventually washing or cleaning of coal could significantly decrease the emission of REEs from coal into the environment.

Analysis of an Electrical Transformer: A Bond Graph Approach

Bond graph models of an electrical transformer including the nonlinear saturation are presented. These models determine the relation between self and mutual inductances, and the leakage and magnetizing inductances of power transformers with two and three windings using the properties of a bond graph. The modelling and analysis using this methodology to three phase power transformers or transformers with internal incipient faults can be extended.

Steady State Transpiration Cooling System in Ni-Cr Open-Cellular Porous Plate

The steady-state temperature for one-dimensional transpiration cooling system has been conducted experimentally and numerically to investigate the heat transfer characteristics of combined convection and radiation. The Nickel –Chrome (Ni-Cr) open-cellular porous material having porosity of 0.93 and pores per inch (PPI) of 21.5 was examined. The upper surface of porous plate was heated by the heat flux of incoming radiation varying from 7.7 - 16.6 kW/m2 whereas air injection velocity fed into the lower surface was varied from 0.36 - 1.27 m/s, and was then rearranged as Reynolds number (Re). For the report of the results in the present study, two efficiencies including of temperature and conversion efficiency were presented. Temperature efficiency indicating how close the mean temperature of a porous heat plate to that of inlet air, and increased rapidly with the air injection velocity (Re). It was then saturated and had a constant value at Re higher than 10. The conversion efficiency, which was regarded as the ability of porous material in transferring energy by convection after absorbed from heat radiation, decreased with increasing of the heat flux and air injection velocity. In addition, it was then asymptotic to a constant value at the Re higher than 10. The numerical predictions also agreed with experimental data very well.