Abstract: Search for a tertiary substructure that geometrically
matches the 3D pattern of the binding site of a well-studied protein provides a solution to predict protein functions. In our previous work,
a web server has been built to predict protein-ligand binding sites
based on automatically extracted templates. However, a drawback of such templates is that the web server was prone to resulting in many
false positive matches. In this study, we present a sequence-order constraint to reduce the false positive matches of using automatically
extracted templates to predict protein-ligand binding sites. The binding site predictor comprises i) an automatically constructed template library and ii) a local structure alignment algorithm for
querying the library. The sequence-order constraint is employed to
identify the inconsistency between the local regions of the query protein and the templates. Experimental results reveal that the sequence-order constraint can largely reduce the false positive matches and is effective for template-based binding site prediction.
Abstract: Work Breakdown Structure (WBS) is one of the
most vital planning processes of the project management since it
is considered to be the fundamental of other processes like
scheduling, controlling, assigning responsibilities, etc. In fact
WBS or activity list is the heart of a project and omission of a
simple task can lead to an irrecoverable result. There are some
tools in order to generate a project WBS. One of the most
powerful tools is mind mapping which is the basis of this article.
Mind map is a method for thinking together and helps a project
manager to stimulate the mind of project team members to
generate project WBS. Here we try to generate a WBS of a
sample project involving with the building construction using the
aid of mind map and the artificial intelligence (AI) programming
language. Since mind map structure can not represent data in a
computerized way, we convert it to a semantic network which can
be used by the computer and then extract the final WBS from the
semantic network by the prolog programming language. This
method will result a comprehensive WBS and decrease the
probability of omitting project tasks.
Abstract: Sensory nerves in the foot play an important part in the diagnosis of various neuropathydisorders, especially in diabetes mellitus.However, a detailed description of the anatomical distribution of the nerves is currently lacking. A computationalmodel of the afferent nerves inthe foot may bea useful tool for the study of diabetic neuropathy. In this study, we present the development of an anatomically-based model of various major sensory nerves of the sole and dorsal sidesof the foot. In addition, we presentan algorithm for generating synthetic somatosensory nerve networks in the big-toe region of a right foot model. The algorithm was based on a modified version of the Monte Carlo algorithm, with the capability of being able to vary the intra-epidermal nerve fiber density in differentregionsof the foot model. Preliminary results from the combinedmodel show the realistic anatomical structure of the major nerves as well as the smaller somatosensory nerves of the foot. The model may now be developed to investigate the functional outcomes of structural neuropathyindiabetic patients.
Abstract: Diatoms are an important group of aquatic ecosystems and diatom-based indices are increasingly becoming important tools for the assessment of ecological conditions in lotic systems. Although the studies are very limited about Turkish rivers, diatom indices were used for monitoring rivers in different basins. In the present study, we used OMNIDIA program for estimation of stream quality. Some indices have less sensitive (IDP, WAT, LOBO, GENRE, TID, CEE, PT), intermediate sensitivities (IDSE, DESCY, IPS, DI-CH, SLA, IDAP), the others higher sensitivities (SID, IBD, SHE, EPI-D). Among the investigated diatom communities, only a few taxa indicated alfa-mesosaprobity and polysaprobity. Most of the sites were characterized by a great relative contribution of eutraphent and tolerant ones as well as oligosaprobic and betamesosaprobic diatoms. In general, SID and IBD indices gave the best results. This study suggests that the structure of benthic diatom communities and diatom indices, especially SID, can be applied for monitoring rivers in Southern Turkey.
Abstract: Image processing for capsule endoscopy requires large
memory and it takes hours for diagnosis since operation time is
normally more than 8 hours. A real-time analysis algorithm of capsule
images can be clinically very useful. It can differentiate abnormal
tissue from health structure and provide with correlation information
among the images. Bleeding is our interest in this regard and we
propose a method of detecting frames with potential bleeding in
real-time. Our detection algorithm is based on statistical analysis and
the shapes of bleeding spots. We tested our algorithm with 30 cases of
capsule endoscopy in the digestive track. Results were excellent where
a sensitivity of 99% and a specificity of 97% were achieved in
detecting the image frames with bleeding spots.
Abstract: An improved topology of a voltage-fed quasi-resonant
soft switching LCrCdc series-parallel half bridge inverter with a constant-frequency for electronic ballast applications is proposed in this paper. This new topology introduces a low-cost solution to
reduce switching losses and circuit rating to achieve high-efficiency
ballast. Switching losses effect on ballast efficiency is discussed
through experimental point of view. In this discussion, an improved
topology in which accomplishes soft switching operation over a wide
power regulation range is proposed. The proposed structure uses reverse recovery diode to provide better operation for the ballast system. A symmetrical pulse wide modulation (PWM) control scheme is implemented to regulate a wide range of out-put power.
Simulation results are kindly verified with the experimental
measurements obtained by ballast-lamp laboratory prototype. Different load conditions are provided in order to clarify the
performance of the proposed converter.
Abstract: In this paper, a recursive algorithm for the
computation of 2-D DCT using Ramanujan Numbers is proposed.
With this algorithm, the floating-point multiplication is completely
eliminated and hence the multiplierless algorithm can be
implemented using shifts and additions only. The orthogonality of
the recursive kernel is well maintained through matrix factorization
to reduce the computational complexity. The inherent parallel
structure yields simpler programming and hardware implementation
and provides
log 1
2
3
2 N N-N+
additions and
N N
2 log
2 shifts which is
very much less complex when compared to other recent multiplierless
algorithms.
Abstract: The selective wet-etching of amorphous and
crystalline region of Sb20Se80 thin films was carried out using organic
based solution e.g. amines. We report the development of an in situ
real-time method to study the wet chemical etching process of thin
films. Characterization of the structure and surface of films studied
by X-ray diffraction, SEM and EBSD methods has been done and
potential application suggested.
Abstract: A theory for optimal filtering of infinite sets of random
signals is presented. There are several new distinctive features of the
proposed approach. First, a single optimal filter for processing any
signal from a given infinite signal set is provided. Second, the filter is
presented in the special form of a sum with p terms where each term
is represented as a combination of three operations. Each operation
is a special stage of the filtering aimed at facilitating the associated
numerical work. Third, an iterative scheme is implemented into the
filter structure to provide an improvement in the filter performance at
each step of the scheme. The final step of the scheme concerns signal
compression and decompression. This step is based on the solution of
a new rank-constrained matrix approximation problem. The solution
to the matrix problem is described in this paper. A rigorous error
analysis is given for the new filter.
Abstract: The main aim of the presented experiments is to
improve behaviour of sandwich structures under dynamic loading,
such as crash or explosion. Several cellular materials are widely used
as core of the sandwich structures and their properties influence
the response of the entire element under impact load. To optimize
their performance requires the characterisation of the core material
behaviour at high strain rates and identification of the underlying
mechanism. This work presents the study of high strain-rate
characteristics of a specific porous lightweight blast energy absorbing
foam using a Split Hopkinson Pressure Bar (SHPB) technique
adapted to perform tests on low strength materials. Two different
velocities, 15 and 30 m.s-1 were used to determine the strain
sensitivity of the material. Foams were designed using two types of
porous lightweight spherical raw materials with diameters of 30-
100 *m, combined with polymer matrix. Cylindrical specimens with
diameter of 15 mm and length of 7 mm were prepared and loaded
using a Split Hopkinson Pressure Bar apparatus to assess the relation
between the composition of the material and its shock wave
attenuation capacity.
Abstract: In recent years, rehabilitation has been the subject of extensive research due to increased spending on building work and repair of built works. In all cases, it is absolutely essential to carry out methods of strengthening or repair of structural elements, and that following an inspection analysis and methodology of a correct diagnosis. The reinforced concrete columns are important elements in building structures. They support the vertical loads and provide bracing against the horizontal loads. This research about the behavior of reinforced concrete rectangular columns, rehabilitated by concrete liner, confinement FRP fabric, steel liner or cage formed by metal corners. It allows comparing the contributions of different processes used perspective section resistance elements rehabilitated compared to that is not reinforced or repaired. The different results obtained revealed a considerable gain in bearing capacity failure of reinforced sections cladding concrete, metal bracket, steel plates and a slight improvement to the section reinforced with fabric FRP. The use of FRP does not affect the weight of the structures, but the use of different techniques cladding increases the weight of elements rehabilitated and therefore the weight of the building which requires resizing foundations.
Abstract: A scaffold is necessary for tooth regeneration because of its three-dimensional geometry. For restoration of defect, it is necessary for the scaffold to be prepared in the shape of the defect. Sponges made from polyvinyl alcohol with formalin cross-linking (PVF sponge) have been used for scaffolds for bone formation in vivo. To induce osteogenesis within the sponge, methods of growing rat bone marrow cells (rBMCs) among the fiber structures in the sponge might be considered. Storage of rBMCs among the fibers in the sponge coated with dextran (10 kDa) was tried. After seeding of rBMCs to PVF sponge immersed in dextran solution at 2 g/dl concentration, osteogenesis was recognized in subcutaneously implanted PVF sponge as a scaffold in vivo. The level of osteocalcin was 25.28±5.71 ng/scaffold and that of Ca was 129.20±19.69 µg/scaffold. These values were significantly higher than those in sponges without dextran coating (p
Abstract: This paper outlines the research conducted to propose na framework of 'Knowledge Society' (KS) in the Malaysian context.
It is important to highlight that the emergence of KS is a result of the rapid growth in knowledge and information. However, the discussion
of KS should not only be limited to the importance of knowledge, but a holistic KS is also determined by other imperative dimensions. This
article discusses the results of a study conducted previously in Malaysia in order to identify the essential dimensions of KS, and
consequently propose a KS framework in the Malaysian context.
Two methods were employed, namely the Delphi technique and semi-structured interviews. The modified Delphi involved five
rounds with ten experts, while the interviews were conducted with two prominent figures in Malaysia. The results support the proposed
framework which contains seven major dimensions in order for Malaysia to become a KS in the future. The dimensions which are
crucial for a holistic Malaysian KS are human capital, spirituality, economy, social, institutional, sustainability, and driven by the ICT.
Abstract: This study reports the preparation of soft magnetic ribbons of Fe-based amorphous alloys using the single-roller melt-spinning technique. Ribbon width varied from 142 mm to 213 mm and, with a thickness of approximately 22 μm 2 μm. The microstructure and magnetic properties of the ribbons were characterized by differential scanning calorimeter (DSC), X-ray diffraction (XRD), vibrating sample magnetometer (VSM), and electrical resistivity measurements (ERM). The amorphous material properties dependence of the cooling rate and nozzle pressure have uneven surface in ribbon thicknesses are investigated. Magnetic measurement results indicate that some region of the ribbon exhibits good magnetic properties, higher saturation induction and lower coercivity. However, due to the uneven surface of 213 mm wide ribbon, the magnetic responses are not uniformly distributed. To understand the transformer magnetic performances, this study analyzes the measurements of a three-phase 2 MVA amorphous-cored transformer. Experimental results confirm that the transformer with a ribbon width of 142 mm has better magnetic properties in terms of lower core loss, exciting power, and audible noise.
Abstract: F-actin fibrils are the cytoskeleton of osteocytes. They react in a dynamic manner to mechanical loading, and strength and
reposition their efforts to reinforce the cells structure. We hypothesize that f-actin is temporarly disrupted after loading and repolymerizes
in a new orientation to oppose the applied load. In vitro studies are conducted to determine f-actin disruption after varying mechanical stimulus parameters that are known to affect bone
formation. Results indicate that the f-actin cytoskeleton is disrupted in vitro as a function of applied mechanical stimulus parameters and
that the f-actin bundles reassemble after loading induced disruption
within 3 minutes after cessation of loading. The disruption of the factin
cytoskeleton depends on the magnitude of stretch, the numbers
of loading cycles, frequency, the insertion of rest between loading
cycles and extracellular calcium. In vivo studies also demonstrate
disruption of the f-actin cytoskeleton in cells embedded in the bone
matrix immediately after mechanical loading. These studies suggest
that adaptation of the f-actin fiber bundles of the cytoskeleton in
response to applied loads occurs by disruption and subsequent repolymerization.
Abstract: Landscape connectivity combines a description of the
physical structure of the landscape with special species- response to
that structure, which forms the theoretical background of applying
landscape connectivity principles in the practices of landscape
planning and design. In this study, a residential development project in
the southern United States was used to explore the meaning of
landscape connectivity and its application in town planning. The vast
rural landscape in the southern United States is conspicuously
characterized by the hedgerow trees or groves. The patchwork
landscape of fields surrounded by high hedgerows is a traditional and
familiar feature of the American countryside. Hedgerows are in effect
linear strips of trees, groves, or woodlands, which are often critical
habitats for wildlife and important for the visual quality of the
landscape. Based on geographic information system (GIS) and
statistical analysis (FRAGSTAT), this study attempts to quantify the
landscape connectivity characterized by hedgerows in south Alabama
where substantial areas of authentic hedgerow landscape are being
urbanized due to the ever expanding real estate industry and high
demand for new residential development. The results of this study
shed lights on how to balance the needs of new urban development and
biodiversity conservation by maintaining a higher level of landscape
connectivity, thus will inform the design intervention.
Abstract: A suspension bridge is the most suitable type of structure for a long-span bridge due to rational use of structural materials. Increased deformability, which is conditioned by appearance of the elastic and kinematic displacements, is the major disadvantage of suspension bridges. The problem of increased kinematic displacements under the action of non-symmetrical load can be solved by prestressing. The prestressed suspension bridge with the span of 200 m was considered as an object of investigations. The cable truss with the cross web was considered as the main load carrying structure of the prestressed suspension bridge. The considered cable truss was optimized by 47 variable factors using Genetic algorithm and FEM program ANSYS. It was stated, that the maximum total displacements are reduced up to 29.9% by using of the cable truss with the rational characteristics instead of the single cable in the case of the worst situated load.
Abstract: Cheating on standardized tests has been a major
concern as it potentially minimizes measurement precision. One
major way to reduce cheating by collusion is to administer multiple
forms of a test. Even with this approach, potential collusion is still
quite large. A Latin-square treatment structure for distributing
multiple forms is proposed to further reduce the colluding potential.
An index to measure the extent of colluding potential is also
proposed. Finally, with a simple algorithm, the various Latin-squares
were explored to find the best structure to keep the colluding
potential to a minimum.
Abstract: Because of architectural condition and structure application, sometimes mass source and stiffness source are not coincidence, and the structure is irregular. The structure is also might be asymmetric as an asymmetric bracing in plan which leads to unbalance distribution of stiffness or because of unbalance distribution of the mass. Both condition lead to eccentricity and torsion in the structure. The deficiency of ordinary code to evaluate the performance of steel structures against earthquake has been caused designing based on performance level or capacity spectrum be used. By using the mentioned methods it is possible to design a structure that its behavior against different earthquakes be predictive. In this article 5- story buildings with different percentage of asymmetric which is because of stiffness changes have been designed. The static and dynamic nonlinear analysis under three acceleration recording has been done. Finally performance level of the structure has been evaluated.
Abstract: IT consultants often take over an important role as an
interface between technological, organizational and managerial
structures. As a result, the services offered are in many cases
assigned to different disciplines which can cause a lack of
transparency on the market for consulting services. However, not all
consulting products are suitable for every company because of
different frameworks and business processes. In this context the
questions arises as to what consulting products are currently offered
and how they can be compared as well as how the market for IT
consulting services is structured on the supply side. The presented
study aims to shed light on the IT consulting market by giving an
overview of the current structure of the supply-side for IT consulting
services as well as proposing a categorization of the currently
available consulting services (consulting fields) in order to provide a
theoretical background for the empirical study. Apart from these
theoretical considerations, the empirical results of field surveys on
the Austrian IT consulting market are presented and analyzed.