Abstract: Experimental study on slicing of sapphire with fixed
abrasive diamond wire saw was conducted in this paper. The process
parameters were optimized through orthogonal experiment of three
factors and four levels. The effects of wire speed, feed speed and
tension pressure on the surface roughness were analyzed. Surface
roughness in cutting direction and feed direction were both detected.
The results show that feed speed plays the most significant role on the
surface roughness of sliced sapphire followed by wire speed and
tension pressure. The optimized process parameters are as follows:
wire speed 1.9 m/s, feed speed 0.187 mm/min and tension pressure
0.18 MPa. In the end, the results were verified by analysis of variance.
Abstract: Gypsum (CaSO4.2H2O) is a mineral that is found in
large quantities in the Turkey and in the World. In this study, the
dissolution of this mineral in the diammonium hydrogen phosphate
solutions has been studied. The dissolution and dissolution kinetics of
gypsum in diammonium hydrogen phosphate solutions will be useful
for evaluating of solid wastes containing gypsum. Parameters such as
diammonium hydrogen phosphate concentration, temperature and
stirring speed affecting on the dissolution rate of the gypsum in
diammonium hydrogen phosphate solutions were investigated. In
experimental studies have researched effectiveness of the selected
parameters. The dissolution of gypsum were examined in two parts at
low and high temperatures. The experimental results were
successfully correlated by linear regression using Statistica program.
Dissolution curves were evaluated shrinking core models for solidfluid
systems. The activation energy was found to be 34.58 kJ/mol
and 44.45 kJ/mol for the low and the high temperatures. The
dissolution of gypsum was controlled by chemical reaction both low
temperatures and high temperatures.
Abstract: Dengue outbreaks are affected by biological,
ecological, socio-economic and demographic factors that vary over
time and space. These factors have been examined separately and still
require systematic clarification. The present study aimed to investigate
the spatial-temporal clustering relationships between these factors and
dengue outbreaks in the northern region of Sri Lanka. Remote sensing
(RS) data gathered from a plurality of satellites were used to develop
an index comprising rainfall, humidity and temperature data. RS data
gathered by ALOS/AVNIR-2 were used to detect urbanization, and a
digital land cover map was used to extract land cover information.
Other data on relevant factors and dengue outbreaks were collected
through institutions and extant databases. The analyzed RS data and
databases were integrated into geographic information systems,
enabling temporal analysis, spatial statistical analysis and space-time
clustering analysis. Our present results showed that increases in the
number of the combination of ecological factor and socio-economic
and demographic factors with above the average or the presence
contribute to significantly high rates of space-time dengue clusters.
Abstract: Morphological interaction of porcine cumulus-oocyte
complexes (pCOCs) was investigated on in vitro condition using
electron microscope (SEM and TEM). The totals of 1,923 oocytes
were round in shape, surrounded by Zona pellucida with layer of
cumulus cells ranging between 59.29-202.14 μm in size. They were
classified into intact-, multi-, partial cumulus cell layer oocyte, and
completely denuded oocyte, at the percentage composition of 22.80%
32.70%, 18.60%, and 25.90 % respectively. The pCOCs classified as
intact- and multi cumulus cell layer oocytes were further culturing at
37°C with 5% CO2, 95% air atmosphere and high humidity for 44 h
in M199 with Earle’s salts supplemented with 10% HTFCS, 2.2
mg/mL NaHCO3, 1 M Hepes, 0.25 mM pyruvate, 15 μg/mL porcine
follicle-stimulating hormone, 1 μg/mL LH, 1μg/mL estradiol with
ethanol, and 50 μg/mL gentamycin sulfate. On electron microscope
study, cumulus cells were found to stick their processes to secrete
substance from the sac-shape end into Zona pellucida of the oocyte
and also communicated with the neighboring cells through their
microvilli on the beginning of incubation period. It is believed that
the cumulus cells communicate with the oocyte by inserting the
microvilli through this gap and embedded in the oocyte cytoplasm
before secreting substance, through the sac-shape end of the
microvilli, to inhibit primary oocyte development at the prophase I.
Morphological changes of the complexes were observed after
culturing for 24-44 h. One hundred percentages of the cumulus layers
were expanded and cumulus cells were peeling off from the oocyte
surface. In addition, the round-shape cumulus cells transformed
themselves into either an elongate shape or a columnar shape, and no
communication between cumulus neighboring cells. After 44 h of
incubation time, diameter of oocytes surrounded by cumulus cells
was larger than 0 h incubation. The effect of hormones in culture
medium is exerted by their receptors present in porcine oocyte. It is
likely that all morphological changes of the complexes after hormone
treatment were to allow maturation of the oocyte. This study
demonstrated that the association of hormones in M199 could
promote porcine follicle activation in 44 h in vitro condition. This
culture system should be useful for studying the regulation of early
follicular growth and development, especially because these follicles represent a large source of oocytes that could be used in vitro for cell
technology.
Abstract: This paper argues nation-building theories that
prioritize democratic governance best explain the successful postindependence
development of Botswana. Three main competing
schools of thought exist regarding the sequencing of policies that
should occur to re-build weakened or failed states. The first posits
that economic development should receive foremost attention, while
democratization and a binding sense of nationalism can wait. A
second group of experts identified constructing a sense of nationalism
among a populace is necessary first, so that the state receives popular
legitimacy and obedience that are prerequisites for development.
Botswana, though, transitioned into a multi-party democracy and
prosperous open economy due to the utilization of traditional
democratic structures, enlightened and accountable leadership, and an
educated technocratic civil service. With these political foundations
already in place when the discovery of diamonds occurred, the
resulting revenues were spent wisely on projects that grew the
economy, improved basic living standards, and attracted foreign
investment. Thus democratization preceded, and therefore provided
an accountable basis for, economic development that might otherwise
have been squandered by greedy and isolated elites to the detriment
of the greater population. Botswana was one of the poorest nations in
the world at the time of its independence in 1966, with little
infrastructure, a dependence on apartheid South Africa for trade, and
a largely subsistence economy. Over the next thirty years, though, its
economy grew the fastest of any nation in the world. The transparent
and judicious use of diamond returns is only a partial explanation, as
the government also pursued economic diversification, mass
education, and rural development in response to public needs.
As nation-building has become a project undertaken by nations
and multilateral agencies such as the United Nations and the North
Atlantic Treaty Organization, Botswana may provide best practices
that others should follow in attempting to reconstruct economically
and politically unstable states.
Abstract: Interaction of Schiff base complexes of Iron and
Manganese: Iron [N, N’ Bis (5- (triphenyl phosphonium methyl)
salicylidene) -1, 2 ethanediamine) chloride, [Fe Salen]Cl; Manganese
[N, N’ Bis (5- (triphenyl phosphonium methyl) salicylidene) -1, 2
ethanediamine) acetate, were investigated by spectroscopic and
isothermal titration calorimetry techniques (ITC).
The absorbance spectra of complexes have shown hyper and
hypochromism in the presence of DNA that is indication of
interaction of complexes with DNA. The linear dichroism (LD)
measurements confirmed the bending of DNA in the presence of
complexes.
Furthermore, Isothermal titration calorimetry experiments
approved that complexes bound to DNA on the base of both
electrostatic and hydrophobic interactions. More, ITC profile exhibits
the existence of two binding phases for the complexes. Antibacterial
activity of ligand and complexes were tested in vitro to evaluate their
activity against the gram positive and negative bacteria.
Abstract: Chemical vapor deposition (CVD) diamond coated
cutting tool has excellent cutting performance, it is the most ideal tool
for the processing of nonferrous metals and alloys, composites,
nonmetallic materials and other difficult-to-machine materials
efficiently and accurately. Depositing CVD diamond coating on the
cemented carbide with high cobalt content can improve its toughness
and strength, therefore, it is very important to research on the
preparation technology and cutting properties of CVD diamond coated
cemented carbide cutting tool with high cobalt content. The
preparation technology of boron-doped diamond (BDD) coating has
been studied and the coated drills were prepared. BDD coating were
deposited on the drills by using the optimized parameters and the SEM
results show that there are no cracks or collapses in the coating.
Cutting tests with the prepared drills against the silumin and aluminum
base printed circuit board (PCB) have been studied. The results show
that the wear amount of the coated drill is small and the machined
surface has a better precision. The coating does not come off during
the test, which shows good adhesion and cutting performance of the
drill.
Abstract: The development of allometric models is crucial to
accurate forest biomass/carbon stock assessment. The aim of this
study was to develop a set of biomass prediction models that will
enable the determination of total tree aboveground biomass for
savannah woodland area in Niger State, Nigeria. Based on the data
collected through biometric measurements of 1816 trees and
destructive sampling of 36 trees, five species specific and one site
specific models were developed. The sample size was distributed
equally between the five most dominant species in the study site
(Vitellaria paradoxa, Irvingia gabonensis, Parkia biglobosa,
Anogeissus leiocarpus, Pterocarpus erinaceous). Firstly, the
equations were developed for five individual species. Secondly these
five species were mixed and were used to develop an allometric
equation of mixed species. Overall, there was a strong positive
relationship between total tree biomass and the stem diameter. The
coefficient of determination (R2 values) ranging from 0.93 to 0.99 P
< 0.001 were realised for the models; with considerable low standard
error of the estimates (SEE) which confirms that the total tree above
ground biomass has a significant relationship with the dbh. F-test
values for the biomass prediction models were also significant at p
Abstract: A well designed and executed Production Planning
and Control (PPC) system is one of the key levers for superior
performance in the current manufacturing set-up. Hence, measuring
the PPC system performance has become a necessity for long term
success. The present study examined PPC related issues which
impact the production capacity and productivity of leather companies
with special focus on Kombolcha Tannery Share Company (KTSC),
Ethiopia. Physical observation, interview, and questionnaire were
used to generate necessary information from the respondents and
reach valid conclusions. Company annual reports were referred and
analyzed to triangulate primary data. Consequently, the study
revealed that KTSC runs below its capacity due to its inefficient PPC
system being in use for which the root causes were identified. The
study thereby conceptualizes a PPC system improvement framework
comprising three pillars viz., management culture, internal capability
and performance measurement together with key considerations in
each case. The study findings enable the company to recognize the
importance of efficient PPC system as a source of competitive
advantage. It also aid managers in evaluating various PPC execution
schemes to enhance productivity.
Abstract: Today, the pollution due to non-degradable material
such as plastics, has led to studies about the development of
environmental-friendly material. Because of biodegradability
obtained from natural sources, polylactid acid (PLA) and ijuk fiber
are interesting to modify into a composite. This material is also
expected to reduce the impact of environmental pollution. Surface
modification of ijuk fiber through alkalinization with 0.25 M NaOH
solution for 30 minutes was aimed to enhance its compatibility to
PLA, in order to improve properties of the composite such as the
mechanical properties. Alkalinization of the ijuk fibers annihilates
some surface components such as lignin, wax and hemicelloluse, so
the pore on the surface clearly appeared, decreasing of the density
and diameter of the ijuk fibers. The change of the ijuk fiber properties
leads to increase the mechanical properties of PLA composites
reinforced the ijuk fibers through strengthening of the mechanical
interlocking with the PLA matrix. An addition to enhance the
distribution of the fibers in the PLA matrix, the stirring during DCM
solvent evaporation from the mixture of the ijuk fibers and the
dissolved-PLA can reduce amount of the trapped-voids and fibers
pull-out phenomena, which can decrease the mechanical properties of
the composite.
Abstract: Ti6Al4V alloy is highly used in the automotive and
aerospace industry due to its good machining characteristics. Micro
EDM drilling is commonly used to drill micro hole on extremely hard
material with very high depth to diameter ratio. In this study, the
parameters of micro-electrical discharge machining (EDM) in drilling
of Ti6Al4V alloy is optimized for higher machining accuracy with
less hole-dilation and hole taper ratio. The micro-EDM machining
parameters includes, peak current and pulse on time. Fuzzy analysis
was developed to evaluate the machining accuracy. The analysis
shows that hole-dilation and hole-taper ratio are increased with the
increasing of peak current and pulse on time. However, the surface
quality deteriorates as the peak current and pulse on time increase.
The combination that gives the optimum result for hole dilation is
medium peak current and short pulse on time. Meanwhile, the
optimum result for hole taper ratio is low peak current and short pulse
on time.
Abstract: Micro-alloyed steel components are used in
automotive industry for the necessity to make the manufacturing
process cycles shorter when compared to conventional steel by
eliminating heat treatment cycles, so an important saving of costs and
energy can be reached by reducing the number of operations. Microalloying
elements like vanadium, niobium or titanium have been
added to medium carbon steels to achieve grain refinement with or
without precipitation strengthening along with uniform
microstructure throughout the matrix. Present study reports the
applicability of medium carbon vanadium micro-alloyed steel in hot
forging. Forgeability has been determined with respect to different
cooling rates, after forging in a hydraulic press at 50% diameter
reduction in temperature range of 900-11000C. Final microstructures,
hardness, tensile strength, and impact strength have been evaluated.
The friction coefficients of different lubricating conditions, viz.,
graphite in hydraulic oil, graphite in furnace oil, DF 150 (Graphite,
Water-Based) die lubricant and dry or without any lubrication were
obtained from the ring compression test for the above micro-alloyed
steel. Results of ring compression tests indicate that graphite in
hydraulic oil lubricant is preferred for free forging and dry lubricant
is preferred for die forging operation. Exceptionally good forgeability
and high resistance to fracture, especially for faster cooling rate has
been observed for fine equiaxed ferrite-pearlite grains, some amount
of bainite and fine precipitates of vanadium carbides and
carbonitrides. The results indicated that the cooling rate has a
remarkable effect on the microstructure and mechanical properties at
room temperature.
Abstract: Doxorubicin, also known as Adriamycin, is an
anthracycline class of drug used in cancer chemotherapy. It is used in
the treatment of non-Hodgkin’s lymphoma, multiple myeloma, acute
leukemia, breast cancer, lung cancer, endometrium cancer and ovary
cancers. It functions via intercalating DNA and ultimately killing
cancer cells. The major side effects of doxorubicin are hair loss,
myelosuppression, nausea & vomiting, oesophagitis, diarrhea, heart
damage and liver dysfunction. The minor modifications in the
structure of compound exhibit large variation in the biological
activity, has prompted us to carry out the synthesis of sulfonamide
derivatives. Sulfonamide is an important feature with broad spectrum
of biological activity such as antiviral, antifungal, diuretics, antiinflammatory,
antibacterial and anticancer activities. Structure of the
synthesized compound N-(1-methyl-2-oxo-2-N-methyl anilinoethyl)
benzene sulfonamide confirmed by proton nuclear magnetic
resonance (1H NMR),13C NMR, Mass and FTIR spectroscopic tools
to assure the position of all protons and hence stereochemistry of the
molecule. Further we have reported the binding potential of
synthesized sulfonamide analogues in comparison to doxorubicin
drug using Auto Dock 4.2 software. Computational binding energy
(B.E.) and inhibitory constant (Ki) has been evaluated for the
synthesized compound in comparison of doxorubicin against Poly
(dA-dT).Poly (dA-dT) and Poly (dG-dC).Poly (dG-dC) sequences.
The in vitro cytotoxic study against human breast cancer cell lines
confirms the better anticancer activity of the synthesized compound
over currently in use anticancer drug doxorubicin. The IC50 value of
the synthesized compound is 7.12 μM whereas for doxorubicin is 7.2
μM.
Abstract: The planning of geological survey works is an
iterative process which involves planner, geologist, civil engineer and
other stakeholders, who perform different roles and have different
points of view. Traditionally, the team used paper maps or CAD
drawings to present the proposal which is not an efficient way to
present and share idea on the site investigation proposal such as
sitting of borehole location or seismic survey lines. This paper
focuses on how a GIS approach can be utilised to develop a webbased
system to support decision making process in the planning of
geological survey works and also to plan site activities carried out by
Singapore Geological Office (SGO). The authors design a framework
of building an interactive web-based GIS system, and develop a
prototype, which enables the users to obtain rapidly existing
geological information and also to plan interactively borehole
locations and seismic survey lines via a web browser. This prototype
system is used daily by SGO and has shown to be effective in
increasing efficiency and productivity as the time taken in the
planning of geological survey works is shortened. The prototype
system has been developed using the ESRI ArcGIS API 3.7 for Flex
which is based on the ArcGIS 10.2.1 platform.
Abstract: The pullout strength had an effect on the stability of
plate screw fixation when inserted in the cervical spine. Nine
different titanium alloy bone screws were used to test the pullout
strength through finite element analysis. The result showed that the
Moss Miami I can bear the highest pullout force at 1,075 N, which
causes the maximum von Mises stress at 858.87 MPa, a value over
the yield strength of titanium. The bone screw should have large
outer diameter, core diameter and proximal root radius to increase the
pullout strength.
Abstract: The wear measuring and wear modelling are
fundamental issues in the industrial field, mainly correlated to the
economy and safety. Therefore, there is a need to study the wear
measurements and wear estimation. Pin-on-disc test is the most
common test which is used to study the wear behaviour. In this paper,
the pin-on-disc (AEROTECH UNIDEX 11) is used for the
investigation of the effects of normal load and hardness of material on
the wear under dry and sliding conditions. In the pin-on-disc rig, two
specimens were used; one, a pin is made of steel with a tip, positioned
perpendicular to the disc, where the disc is made of aluminium. The
pin wear and disc wear were measured by using the following
instruments: The Talysurf instrument, a digital microscope, and the
alicona instrument. The Talysurf profilometer was used to measure
the pin/disc wear scar depth, digital microscope was used to measure
the diameter and width of wear scar, and the alicona was used to
measure the pin wear and disc wear. After that, the Archard model,
American Society for Testing and Materials model (ASTM), and
neural network model were used for pin/disc wear modelling.
Simulation results were implemented by using the Matlab program.
This paper focuses on how the alicona can be used for wear
measurements and how the neural network can be used for wear
estimation.
Abstract: In this paper, two options of anodic alumina barrier
layer thinning have been demonstrated. The approaches varied with
the duration of the voltage step. It was found that too long step of the
barrier layer thinning process leads to chemical etching of the
nanopores on their top. At the bottoms pores are not fully opened
what is disadvantageous for further applications in nanofabrication.
On the other hand, while the duration of the voltage step is controlled
by the current density (value of the current density cannot exceed
75% of the value recorded during previous voltage step) the pores are
fully opened. However, pores at the bottom obtained with this
procedure have smaller diameter, nevertheless this procedure
provides electric contact between the bare aluminum (substrate) and
electrolyte, what is suitable for template assisted electrodeposition,
one of the most cost-efficient synthesis method in nanotechnology.
Abstract: In this research the effects of adding silica and
alumina nanoparticles on flow ability and compressive strength of
cementitious composites based on Portland cement were investigated.
In the first stage, the rheological behavior of different samples
containing nanosilica, nanoalumina and polypropylene, polyvinyl
alcohol and polyethylene fibers were evaluated. With increasing of
nanoparticles in fresh samples, the slump flow diameter reduced.
Fibers reduced the flow ability of the samples and viscosity
increased. With increasing of the micro silica particles to cement
ratio from 2/1 to 2/2, the slump flow diameter increased. By adding
silica and alumina nanoparticles up to 3% and 2% respectively, the
compressive strength increased and after decreased. Samples
containing silica nanoparticles and fibers had the highest compressive
strength.
Abstract: The study of organisations’ information security
cultures has attracted scholars as well as healthcare services industry
to research the topic and find appropriate tools and approaches to
develop a positive culture. The vast majority of studies in Saudi
national health services are on the use of technology to protect and
secure health services information. On the other hand, there is a lack
of research on the role and impact of an organisation’s cultural
dimensions on information security. This research investigated and
analysed the role and impact of cultural dimensions on information
security in Saudi Arabia health service. Hypotheses were tested and
two surveys were carried out in order to collect data and information
from three major hospitals in Saudi Arabia (SA). The first survey
identified the main cultural-dimension problems in SA health
services and developed an initial information security culture
framework model. The second survey evaluated and tested the
developed framework model to test its usefulness, reliability and
applicability. The model is based on human behaviour theory, where
the individual’s attitude is the key element of the individual’s
intention to behave as well as of his or her actual behaviour. The
research identified a set of cultural and sub-cultural dimensions in SA
health information security and services.
Abstract: The adsorption efficiency of fired clayey pellets of 5
and 8 mm diameter size for Cu(II) and Zn(II) ion removal from a
waste printing developer was studied. In order to investigate the
influence of contact time, adsorbent mass and pellet size on the
adsorption efficiency the batch mode was carried out. Faster uptake
of copper ion was obtained with the fired clay pellets of 5 mm
diameter size within 30 minutes. The pellets of 8 mm diameter size
showed the higher equilibrium time (60 to 75 minutes) for copper and
zinc ion. The results pointed out that adsorption efficiency increases
with the increase of adsorbent mass. The maximal efficiency is
different for Cu(II) and Zn(II) ion due to the pellet size. Therefore,
the fired clay pellets of 5 mm diameter size present an effective
adsorbent for Cu(II) ion removal (adsorption efficiency is 63.6%),
whereas the fired clay pellets of 8 mm diameter size are the best
alternative for Zn(II) ion removal (adsorption efficiency is 92.8%)
from a waste printing developer.