Abstract: Liver segmentation from medical images poses more
challenges than analogous segmentations of other organs. This
contribution introduces a liver segmentation method from a series of
computer tomography images. Overall, we present a novel method for
segmenting liver by coupling density matching with shape priors.
Density matching signifies a tracking method which operates via
maximizing the Bhattacharyya similarity measure between the
photometric distribution from an estimated image region and a model
photometric distribution. Density matching controls the direction of
the evolution process and slows down the evolving contour in regions
with weak edges. The shape prior improves the robustness of density
matching and discourages the evolving contour from exceeding liver’s
boundaries at regions with weak boundaries. The model is
implemented using a modified distance regularized level set (DRLS)
model. The experimental results show that the method achieves a
satisfactory result. By comparing with the original DRLS model, it is
evident that the proposed model herein is more effective in addressing
the over segmentation problem. Finally, we gauge our performance of
our model against matrices comprising of accuracy, sensitivity, and
specificity.
Abstract: The agenda of showing the scheduled time for
performing certain tasks is known as timetabling. It is widely used in
many departments such as transportation, education, and production.
Some difficulties arise to ensure all tasks happen in the time and
place allocated. Therefore, many researchers invented various
programming models to solve the scheduling problems from several
fields. However, the studies in developing the general integer
programming model for many timetabling problems are still
questionable. Meanwhile, this thesis describes about creating a
general model which solves different types of timetabling problems
by considering the basic constraints. Initially, the common basic
constraints from five different fields are selected and analyzed. A
general basic integer programming model was created and then
verified by using the medium set of data obtained randomly which is
much similar to realistic data. The mathematical software, AIMMS
with CPLEX as a solver has been used to solve the model. The model
obtained is significant in solving many timetabling problems easily
since it is modifiable to all types of scheduling problems which have
same basic constraints.
Abstract: Anogeissus leiocarpus (Combretaceae) is well known
for its medicinal uses in African traditional medicine, for treating
many human diseases mainly skin diseases and infections. Mycetoma
disease is a fungal and/ or bacterial skininfection, mainly cause by
Madurella mycetomatis fungus. This study was carried out in vitro to
investigate the antifungal activity of Anogeissus leiocarpus leaf
extracts against the isolated pathogenic Madurella mycetomatis, by
using the NCCLS modified method compared to Ketoconazole
standard drug, and MTT assay. The bioactive fraction was subjected
to chemical analysis implementing different chromatographic
analytical methods (TLC, HPLC, and LC-MS/MS). The results
showed significance antifungal activity of A. leiocarpus leaf extracts
against the isolated pathogenic M. mycetomatis, compared to negative
and positive controls. The chloroform fraction showed the highest
antifungal activity. The chromatographic analysis of the chloroform
fraction with the highest activity showed the presence of important
bioactive compounds such as ellagic and flavellagic acids derivatives,
flavonoids and stilbenoid, which are well known for their antifungal
activity.
Abstract: As a result of the ambiguity and complexity
surrounding anaerobic digester foaming, efforts have been made by
various researchers to understand the process of anaerobic digester
foaming so as to proffer a solution that can be universally applied
rather than site specific. All attempts ranging from experimental
analysis to comparative review of other process has not fully
explained the conditions and process of foaming in anaerobic
digester. Studying the current available knowledge on foam
formation and relating it to anaerobic digester process and operating
condition, this piece of work presents a succinct and enhanced
understanding of foaming in anaerobic digesters as well as
introducing a simple method to identify the onset of anaerobic
digester foaming based on analysis of historical data from a field
scale system.
Abstract: In order to investigate the prebiotic potential of
oligosaccharides prepared by chemical hydrolysis of water-soluble
polysaccharides (WSP) from Zizyphus lotus leaves, the effect of
oligosaccharides on bacterial growth was studied. The chemical
composition of WSP was evaluated by colorimetric assays revealed
the average values: 7.05±0.73% proteins and 86.21±0.74%
carbohydrates, among them 64.81±0.42% is neutral sugar and the rest
16.25±1.62% is uronic acids. The characterization of
monosaccharides was determined by high performance anion
exchange chromatography with pulsed amperometric detection
(HPAEC-PAD) was found to be composed of galactose (23.95%),
glucose (21.30%), rhamnose (20.28%), arabinose (9.55%), and
glucuronic acid (22.95%). The effects of oligosaccharides on the
growth of lactic acid bacteria were compared with those of fructooligosaccharide
(RP95). The oligosaccharides concentration was
1g/L of Man, Rogosa, Sharpe broth. Bacterial growth was assessed
during 2, 4.5, 6.5, 9, 12, 16 and 24 h by measuring the optical density
of the cultures at 600 nm (OD600) and pH values. During
fermentation, pH in broth cultures decreased from 6.7 to 5.87±0.15.
The enumeration of lactic acid bacteria indicated that
oligosaccharides led to a significant increase in bacteria (P≤0.05)
compared to the control. The fermentative metabolism appeared to be
faster on RP95 than on oligosaccharides from Zizyphus lotus leaves.
Both RP95 and oligosaccharides showed clear prebiotic effects, but
had differences in fermentation kinetics because of to the different
degree of polymerization. This study shows the prebiotic
effectiveness of oligosaccharides, and provides proof for the selection
of leaves of Zizyphus lotus for use as functional food ingredients.
Abstract: In the recent past, discussing about sex among
children and youths was frowned at by traditional norms and as such
sexual discussions and behavior were approached with great respect.
Things are actually falling apart with the increasing number of young
people that engage in premarital sex. Due to lack of experience and
sex education, many young people are becoming increasingly
exposed to the risk of HIV infection. In the light of the above, this
study discussed premarital sex, HIV, and use of condom among
youths in Nigeria. Data for this study came from 2013 Nigeria
Demographic and Health Survey and other secondary data. The
survey revealed that only 18.5 percent of young women that had sex
in the 12 months preceding the survey used condom. Out of 3306
never-married sexually active men and women, 1728 representing 52
percent live in urban areas and 43 percent of them did not use
condom during sexual intercourse in the 12 months preceding the
survey. This study concludes that for there to be reduction in
prevalence of HIV/AIDS among Nigerian youths, there is need for
concerted effort to be made towards educating youths on the
expedient of the use of condom during sexual intercourse.
Abstract: This paper describes the development of a DNA-based
nanobiosensor to detect the dengue virus in mosquito using
electrically active magnetic (EAM) nanoparticles as concentrator and
electrochemical transducer. The biosensor detection encompasses
two sets of oligonucleotide probes that are specific to the dengue
virus: the detector probe labeled with the EAM nanoparticles and the
biotinylated capture probe. The DNA targets are double hybridized to
the detector and the capture probes and concentrated from
nonspecific DNA fragments by applying a magnetic field.
Subsequently, the DNA sandwiched targets (EAM-detector probe–
DNA target–capture probe-biotin) are captured on streptavidin
modified screen printed carbon electrodes through the biotinylated
capture probes. Detection is achieved electrochemically by measuring
the oxidation–reduction signal of the EAM nanoparticles. Results
indicate that the biosensor is able to detect the redox signal of the
EAM nanoparticles at dengue DNA concentrations as low as 10
ng/μl.
Abstract: Diets high in processed foods have been found to lack
essential micro-nutrients for optimum human development and
overall health. Some micro-nutrients such as copper (Cu) have been
found to enhance the inflammatory response through its oxidative
functions, thereby having a role in cardiovascular disease, metabolic
syndrome, diabetes and related complications. This research study
was designed to determine if food crops could be bio-fortified with
micro-nutrients by growing sprouts on mineral fortified fiber mats. In
the feasibility study described in this contribution, recycled cellulose
fibers and clay, saturated with either micro-nutrient copper ions or
copper nanoparticles, were converted to a novel mineral-cellulose
fiber carrier of essential micro-nutrient and of antimicrobial
properties. Seeds of Medicago sativa (alfalfa), purchased from a
commercial, organic supplier were germinated on engineered
cellulose fiber mats. After the appearance of the first leaves, the
sprouts were dehydrated and analyzed for Cu content. Nutrient
analysis showed ~2 increase in Cu of the sprouts grown on the fiber
mats with copper particles, and ~4 increase on mats with ionic copper
as compared to the control samples. This study illustrates the
potential for the use of engineered mats as a viable way to increase
the micro-nutrient composition of locally-grown food crops and the
need for additional research to determine the uptake, nutritional
implications and risks of micro-nutrient bio-fortification.
Abstract: The current statuses of lifetime test of LaB6 hollow
cathode at the Lanzhou Institute of Physics (LIP), China, was
described. 5A LaB6 hollow cathode was design for LIPS-200 40mN
Xenon ion thruster, and it could be used for LHT-100 80 mN Hall
thruster, too. Life test of the discharge and neutralizer modes of LHC-5
hollow cathode were stared in October 2011, and cumulative operation
time reached 17,300 and 16,100 hours in April 2015, respectively. The
life of cathode was designed more than 11,000 hours. Parameters of
discharge and key structure dimensions were monitored in different
stage of life test indicated that cathodes were health enough. The test
will continue until the cathode cannot work or operation parameter is
not in normally. The result of the endurance test of cathode
demonstrated that the LaB6 hollow cathode is satisfied for the required
of thruster in life and performance.
Abstract: The paper discusses the problem of load transport
using farm tractors and road tractor units. This type of carriage of
goods is often done with farm vehicles. The tests were performed
with the PEMS equipment (Portable Emission Measurement System)
under actual traffic conditions. The vehicles carried a load of 20000
kg. This research method is one of the most desired because it
provides reliable information on the actual vehicle emissions and fuel
consumption (carbon balance method). For the tests, a route was
selected that simulated a trip from a small town to a food-processing
facility located in a city. The analysis of the obtained results gave a
clear answer as to what vehicles need to be used for carriage of this
type of cargo in terms of exhaust emissions and fuel consumption.
Abstract: Routing in adhoc networks is a challenge as nodes are
mobile, and links are constantly created and broken. Present ondemand
adhoc routing algorithms initiate route discovery after a path
breaks, incurring significant cost to detect disconnection and
establish a new route. Specifically, when a path is about to be broken,
the source is warned of the likelihood of a disconnection. The source
then initiates path discovery early, avoiding disconnection totally. A
path is considered about to break when link availability decreases.
This study modifies Adhoc On-demand Multipath Distance Vector
routing (AOMDV) so that route handoff occurs through link
availability estimation.
Abstract: Given the increase in the number of e-commerce sites,
the number of competitors has become very important. This means
that companies have to take appropriate decisions in order to meet the
expectations of their customers and satisfy their needs. In this paper,
we present a case study of applying LRFM (length, recency,
frequency and monetary) model and clustering techniques in the
sector of electronic commerce with a view to evaluating customers’
values of the Moroccan e-commerce websites and then developing
effective marketing strategies. To achieve these objectives, we adopt
LRFM model by applying a two-stage clustering method. In the first
stage, the self-organizing maps method is used to determine the best
number of clusters and the initial centroid. In the second stage, kmeans
method is applied to segment 730 customers into nine clusters
according to their L, R, F and M values. The results show that the
cluster 6 is the most important cluster because the average values of
L, R, F and M are higher than the overall average value. In addition,
this study has considered another variable that describes the mode of
payment used by customers to improve and strengthen clusters’
analysis. The clusters’ analysis demonstrates that the payment method is
one of the key indicators of a new index which allows to assess the
level of customers’ confidence in the company's Website.
Abstract: Numerical study of the static response of
homogeneous clay stratum considering a wide range of cohesion and
subject to foundation loads is presented. The linear elastic–perfectly
plastic constitutive relation with the von Mises yield criterion were
utilised to develop a numerically cost effective finite element model
for the soil while imposing a rigid body constrain to the foundation
footing. From the analyses carried out, estimate of the bearing
capacity factor, Nc as well as the ultimate load-carrying capacities of
these soils, effect of cohesion on foundation settlements, stress fields
and failure propagation were obtained. These are consistent with
other findings in the literature and hence can be a useful guide in
design of safe foundations in clay soils for buildings and other
structure.
Abstract: Broiler slaughter waste has become a major source of
pollution throughout the world. Utilization of broiler slaughter waste
by dry rendering process produced Rendered Chicken Oil (RCO), a
cheap raw material for biodiesel production and Carcass Meal a feed
ingredient for pets and fishes. Conversion of RCO into biodiesel may
open new vistas for generating wealth from waste besides controlling
the major havoc of environmental pollution. A two-step process to
convert RCO to good quality Biodiesel was invented. Acid catalysed
esterification of FFA followed by base catalysed transesterification of
triglycerides was carried out after meticulously standardizing the
methanol molar ratio, catalyst concentration, reaction temperature,
and reaction time to obtain the maximum biodiesel yield of 97.62%
and lowest glycerol yield of 6.96%. RCO biodiesel blend was tested
in a CRDI diesel engine. The results revealed that the blending of
commercial diesel with 20% RCO biodiesel (B20) lead to less engine
wear, a quieter engine and better fuel economy. The better lubricating
qualities of RCO B20 prevented over heating of engine, which
prolongs the engine life. RCO B20 can reduce the import of crude oil
and substantially reduce the engine emissions as proved by
significantly lower smoke levels, thus mitigating climatic changes.
Abstract: Lagos urban mini bus drivers play a critical role in the
transportation sector. The current major mode of transportation
within Lagos metropolis remains road transportation and this
confirms the relevance of urban mini-bus drivers in transporting the
populace to their various destinations. Other modes of transportation
such as the train and waterways are currently inadequate. Various
threats to the well-being of urban bus drivers include congested
traffic typical of modern day lifestyles, dwindling financial returns
due to long hours in traffic, fewer hours of sleep, inadequate diet,
time pressure, and assaults related to fare disputes. Several healthrelated
problems have been documented to be associated with urban
bus driving. For instance, greater rates of hypertension, obesity and
cholesterol level have been reported. Research studies are yet to
identify the influence of age and marital status on the well-being of
urban mini-bus drivers in Lagos metropolis. A study of this nature is
necessary as it is culturally perceived in Nigeria that older and
married people are especially influenced by family affiliation and
would behave in ways that would project positive outcomes. The
study sample consisted of 150 urban mini-bus drivers who were
conveniently sampled from six (6) different terminuses where their
journey begins and terminates. The well-being questionnaire was
administered to participants. The criteria for inclusion in the study
included the ability to read in English language and the confirmation
that interested participants were on duty and suited to be driving
mini-buses. Due to the nature of the job of bus driving, the researcher
administered the questionnaires on participants who were free and
willing to respond to the survey. All participants were males of
various age groups and of different marital statuses. Results of
analyses conducted revealed no significant influence of age and
marital status on the well-being of urban mini-bus drivers. This
indicates that the well-being of urban mini bus drivers is not
influenced by age or marital status. The findings of this study have
cultural implications. It negates the popularly held belief that older
and married people care more about their well-being than younger
and single people. It brings to fore the need to also identify and
consider other factors when certifying people for the job of urban bus
driving.
Abstract: Various nanomaterials can be used as a drug delivery
vehicles in nanomedicine, called nanocarriers. They can either be
organic or inorganic, synthetic or natural-based. Although synthetic
nanocarriers are easier to produce, they can often be toxic for the
organism and thus not suitable for use in treatment. From naturalbased
nanocarriers, the most commonly used are protein cages or
viral capsids. In this work, virus bacteriophage λ was used for
delivery of different cytotoxic drugs (cisplatin, carboplatin,
oxaliplatin and doxorubicin). Large quantities of phage λ were
obtained from phage λ-producing strain of E. coli cultivated in
medium with 0.2% maltose. After killing of E. coli with chloroform
and its removal by centrifugation, the phage was concentrated by
ultracentrifugation at 130 000×g and 4°C for 3 h. The encapsulation
of the drugs was performed by infusion method and four different
concentrations of the drugs were encapsulated (200; 100; 50; 25
μg·mL-1). Free drug molecules were removed by filtration. The
encapsulation was verified using the absorbance for doxorubicin and
atomic absorption spectrometry for platinum cytostatics. The amount
of encapsulated drug linearly increased with the increasing
concentration of applied drug with the determination coefficient
R2=0.989 for doxorubicin; R2=0.967 for cisplatin; R2=0.989 for
carboplatin and R2=0.996 for oxaliplatin. The overall encapsulation
efficiency was calculated as 50% for doxorubicin; 8% for cisplatin;
6% for carboplatin and 10% for oxaliplatin.
Abstract: Recovering resources from water purification sludge
(WPS) have been gradually stipulated in environmental protection
laws and regulations in many nations. Hence, reusing the WPS is
becoming an important topic, and recovering alum from WPS is one of
the many practical alternatives. Most previous research efforts have
been conducted on studying the amphoteric characteristic of aluminum
hydroxide for investigating the optimum pH range to dissolve the
Al(III) species from WPS, but it has been lack of reaction kinetics or
mechanisms related discussion. Therefore, in this investigation, water
purification sludge (WPS) solution was broken by ultrasound to make
particle size of reactants smaller, specific surface area larger.
According to the reaction kinetics, these phenomena let the dissolved
aluminum salt quantity increased and the reaction rate go faster.
Abstract: Millions of girls are forcibly married during the
transitional period between puberty and adulthood. At a stage of
vulnerability cultural practices, religious rights and social standards
place her in a position where she is catapult into womanhood. An
advocate against forced child marriage could argue that child rights,
cultural rights, religious rights, right to marry, right to life, right to
health, right to education, right to be free from slavery, right to be
free from torture, right to consent to marriage are all violated by the
practice of child marriage. The author is this advocate and this paper
will present how some of these rights are violated and establish the
need for change.
Abstract: Chatter vibrations, occurring during cutting process,
cause vibration between the cutting tool and workpiece, which
deteriorates surface roughness and reduces tool life. The purpose of
this study is to investigate the influence of cutting parameters and
tool construction on surface roughness and vibration in turning of
aluminum alloy AA2024. A new design of cutting tool is proposed,
which is filled up with epoxy granite in order to improve damping
capacity of the tool. Experiments were performed at the lathe using
carbide cutting insert coated with TiC and two different cutting tools
made of AISI 5140 steel. Taguchi L9 orthogonal array was applied to
design of experiment and to optimize cutting conditions. By the help
of signal-to-noise ratio and analysis of variance the optimal cutting
condition and the effect of the cutting parameters on surface
roughness and vibration were determined. Effectiveness of Taguchi
method was verified by confirmation test. It was revealed that new
cutting tool with epoxy granite has reduced vibration and surface
roughness due to high damping properties of epoxy granite in
toolholder.
Abstract: Noninvasive diagnostics of diseases via breath
analysis has attracted considerable scientific and clinical interest for
many years and become more and more promising with the rapid
advancements in nanotechnology and biotechnology. The volatile
organic compounds (VOCs) in exhaled breath, which are mainly
blood borne, particularly provide highly valuable information about
individuals’ physiological and pathophysiological conditions.
Additionally, breath analysis is noninvasive, real-time, painless, and
agreeable to patients. We have developed a wireless sensor array
based on single-stranded DNA (ssDNA)-functionalized single-walled
carbon nanotubes (SWNT) for the detection of a number of
physiological indicators in breath. Seven DNA sequences were used
to functionalize SWNT sensors to detect trace amount of methanol,
benzene, dimethyl sulfide, hydrogen sulfide, acetone, and ethanol,
which are indicators of heavy smoking, excessive drinking, and
diseases such as lung cancer, breast cancer, and diabetes. Our test
results indicated that DNA functionalized SWNT sensors exhibit
great selectivity, sensitivity, and repeatability; and different
molecules can be distinguished through pattern recognition enabled
by this sensor array. Furthermore, the experimental sensing results
are consistent with the Molecular Dynamics simulated ssDNAmolecular
target interaction rankings. Thus, the DNA-SWNT sensor
array has great potential to be applied in chemical or biomolecular
detection for the noninvasive diagnostics of diseases and personal
health monitoring.