Abstract: Mechanical interaction between endothelial cells (ECs) and the extracellular matrix (or collagen gel) is known to influence the sprouting response of endothelial cells during angiogenesis. This influence is believed to impact on the capability of endothelial cells to sense soluble chemical cues. Quantitative analysis of endothelial-cell-mediated displacement of the collagen gel provides a means to explore this mechanical interaction. Existing analysis in this context is generally limited to 2D settings. In this paper, we investigate the mechanical interaction between endothelial cells and the extracellular matrix in terms of the endothelial-cellmediated displacement of the collagen gel in both 2D and 3D. Digital image correlation and Digital volume correlation are applied on confocal reflectance image stacks to analyze cell-mediated displacement of the gel. The skeleton of the sprout is extracted from phase contrast images and superimposed on the displacement field to further investigate the link between the development of the sprout and the displacement of the gel.
Abstract: The development of Internet technology in recent years has led to a more active role of users in creating Web content. This has significant effects both on individual learning and collaborative knowledge building. This paper will present an integrative framework model to describe and explain learning and knowledge building with shared digital artifacts on the basis of Luhmann-s systems theory and Piaget-s model of equilibration. In this model, knowledge progress is based on cognitive conflicts resulting from incongruities between an individual-s prior knowledge and the information which is contained in a digital artifact. Empirical support for the model will be provided by 1) applying it descriptively to texts from Wikipedia, 2) examining knowledge-building processes using a social network analysis, and 3) presenting a survey of a series of experimental laboratory studies.
Abstract: The prediction of financial time series is a very
complicated process. If the efficient market hypothesis holds, then the predictability of most financial time series would be a rather
controversial issue, due to the fact that the current price contains already all available information in the market. This paper extends
the Adaptive Neuro Fuzzy Inference System for High Frequency
Trading which is an expert system that is capable of using fuzzy reasoning combined with the pattern recognition capability of neural networks to be used in financial forecasting and trading in high
frequency. However, in order to eliminate unnecessary input in the
training phase a new event based volatility model was proposed.
Taking volatility and the scaling laws of financial time series into consideration has brought about the development of the Intraday Seasonality Observation Model. This new model allows the observation of specific events and seasonalities in data and subsequently removes any unnecessary data. This new event based
volatility model provides the ANFIS system with more accurate input
and has increased the overall performance of the system.
Abstract: Since the 1980s, banks and financial service institutions have been running in an endless race of innovation to cope with the advancing technology, the fierce competition, and the more sophisticated and demanding customers. In order to guide their innovation efforts, several researches were conducted to identify the success and failure factors of new financial services. These mainly included organizational factors, marketplace factors and new service development process factors. They almost all emphasized the importance of customer and market orientation as a response to the highly perceptual and intangible characteristics of financial services. However, they deemphasized the critical characteristics of high involvement of risk and close correlation with the economic conditions, a factor that heavily contributed to the Global financial Crisis of 2008. This paper reviews the success and failure factors of new financial services. It then adds new perspectives emerging from the analysis of the role of innovation in the global financial crisis.
Abstract: Boon Rawd Brewery is a beer company based in
Thailand that has an exemplary image, both as a good employer and a
well-managed company with a strong record of social responsibility.
The most famous of the company’s products is Singha beer. To study
the company’s marketing strategy, a case study analysis was
conducted together with qualitative research methods. The study
analyzed the marketing strategy of Boon Rawd Brewery before the
liberalization of the liquor market in 2000. The company’s marketing
strategies consisted of the following: product line strategy, product
development strategy, block channel strategy, media strategy, trade
strategy, and consumer incentive strategy. Additionally, the company
employed marketing mix strategy based on the 4Ps: product, price,
promotion and place (of distribution).
Abstract: With the development of virtual communities, there is
an increase in the number of members in Virtual Communities (VCs).
Many join VCs with the objective of sharing their knowledge and
seeking knowledge from others. Despite the eagerness of sharing
knowledge and receiving knowledge through VCs, there is no
standard of assessing ones knowledge sharing capabilities and
prospects of knowledge sharing. This paper developed a vector space
model to assess the knowledge sharing prospect of VC users.
Abstract: There are many kinds of metal borates found not only
in nature but also synthesized in the laboratory such as magnesium
borates. Due to its excellent properties, as remarkable ceramic
materials, they have also application areas in anti-wear and friction
reducing additives as well as electro-conductive treating agents. The
synthesis of magnesium borate powders can be fulfilled simply with
two different methods, hydrothermal and thermal synthesis.
Microwave assisted method, also another way of producing
magnesium borate, can be classified into thermal synthesis because of
using the principles of solid state synthesis. It also contributes
producing particles with small size and high purity in nano-size
material synthesize. In this study the production of magnesium
borates, are aimed using MgCl2.6H2O and H3BO3. The identification
of both starting materials and products were made by the equipments
of, X-Ray Diffraction (XRD) and Fourier Transform Infrared
Spectroscopy (FT-IR). After several synthesis steps magnesium
borates were synthesized and characterized by XRD and FT-IR, as
well.
Abstract: Developments in scientific and technical area cause to use new methods and techniques in education, as is the case in all fields. Especially, the internet contributes a variety of new methods to design virtual and real time laboratory applications in education. In this study, a real time virtual laboratory is designed and implemented for analog and digital communications laboratory experiments by using Lab VIEW program for Marmara University Electronics-Communication Department. In this application, students can access the virtual laboratory web site and perform their experiments without any limitation of time and location so as the students can observe the signals by changing the parameters of the experiment and evaluate the results.
Abstract: Light is one of the most important qualitative and
symbolic factors and has a special position in architecture and urban
development in regard to practical function. The main function of
light, either natural or artificial, is lighting up the environment and
the constructional forms which is called lighting. However, light is
used to redefine the urban spaces by architectural genius with regard
to three aesthetic, conceptual and symbolic factors. In architecture
and urban development, light has a function beyond lighting up the
environment, and the designers consider it as one of the basic
components. The present research aims at studying the function of
light and color in architectural view and their effects in buildings.
Abstract: The study was a case study analysis about Thai Asia
Pacific Brewery Company. The purpose was to analyze the
company’s marketing objective, marketing strategy at company level,
and marketing mix before liquor liberalization in 2000. Methods used
in this study were qualitative and descriptive research approach
which demonstrated the following results of the study demonstrated
as follows: (1) Marketing objective was to increase market share of
Heineken and Amtel, (2) the company’s marketing strategies were
brand building strategy and distribution strategy. Additionally, the
company also conducted marketing mix strategy as follows. Product
strategy: The company added more beer brands namely Amstel and
Tiger to provide additional choice to consumers, product and
marketing research, and product development. Price strategy: the
company had taken the following into consideration: cost,
competitor, market, economic situation and tax. Promotion strategy:
the company conducted sales promotion and advertising. Distribution
strategy: the company extended channels its channels of distribution
into food shops, pubs and various entertainment places. This strategy
benefited interested persons and people who were engaged in the beer
business.
Abstract: This paper deals with the development of a Jacobean model for a 4-axes indigenously developed scara robot arm in the laboratory. This model is used to study the relation between the velocities and the forces in the robot while it is doing the pick and place operation.
Abstract: Explosions may cause intensive damage to buildings
and sometimes lead to total and progressive destruction. Pressures
induced by explosions are one of the most destructive loads a
structure may experience. While designing structures for great
explosions may be expensive and impractical, engineers are looking
for methods for preventing destructions resulted from explosions. A
favorable structural system is a system which does not disrupt totally
due to local explosion, since such structures sustain less loss in
comparison with structural ones which really bear the load and
suddenly disrupt. Designing and establishing vital and necessary
installations in a way that it is resistant against direct hit of bomb and
rocket is not practical, economical, or expedient in many cases,
because the cost of construction and installation with such
specifications is several times more than the total cost of the related
equipment.
Abstract: Despite so many years- development, the mainstream of workflow solutions from IT industries has not made ad-hoc workflow-support easy or inexpensive in MIS. Moreover, most of academic approaches tend to make their resulted BPM (Business Process Management) more complex and clumsy since they used to necessitate modeling workflow. To cope well with various ad-hoc or casual requirements on workflows while still keeping things simple and inexpensive, the author puts forth first the TSM design pattern that can provide a flexible workflow control while minimizing demand of predefinitions and modeling workflow, which introduces a generic approach for building BPM in workflow-aware MISs (Management Information Systems) with low development and running expenses.
Abstract: This article considers with the influence of selected economic indicators for the development of the Zlin region. Development of the region is mainly influenced by business entities which are located in the region, as well as investors who contribute to the development of regions. For the development of the region it is necessary for skilled workers remain in the region and not to leave these skilled workers. The above-mentioned and other factors are affecting the development of each region.
Abstract: Matrix metalloproteinase-3 (MMP3) is key member
of the MMP family, and is known to be present in coronary
atherosclerotic. Several studies have demonstrated that MMP-3
5A/6A polymorphism modify each transcriptional activity in allele
specific manner. We hypothesized that this polymorphism may play
a role as risk factor for development of coronary stenosis. The aim of
our study was to estimate MMP-3 (5A/6A) gene polymorphism on
interindividual variability in risk for coronary stenosis in an Iranian
population.DNA was extracted from white blood cells and genotypes
were obtained from coronary stenosis cases (n=95) and controls
(n=100) by PCR (polymerase chain reaction) and restriction
fragment length polymorphism techniques. Significant differences
between cases and controls were observed for MMP3 genotype
frequencies (X2=199.305, p< 0.001); the 6A allele was less
frequently seen in the control group, compared to the disease group
(85.79 vs. 78%, 6A/6A+5A/6A vs. 5A/5A, P≤0.001). These data
imply the involvement of -1612 5A/6A polymorphism in coronary
stenosis, and suggest that probably the 6A/6A MMP-3 genotype is a
genetic susceptibility factor for coronary stenosis.
Abstract: Intellectual capital measurement is a central aspect of knowledge management. The measurement and the evaluation of intangible assets play a key role in allowing an effective management of these assets as sources of competitiveness. For these reasons, managers and practitioners need conceptual and analytical tools taking into account the unique characteristics and economic significance of Intellectual Capital. Following this lead, we propose an efficiency and productivity analysis of Intellectual Capital, as a determinant factor of the company competitive advantage. The analysis is carried out by means of Data Envelopment Analysis (DEA) and Malmquist Productivity Index (MPI). These techniques identify Bests Practice companies that have accomplished competitive advantage implementing successful strategies of Intellectual Capital management, and offer to inefficient companies development paths by means of benchmarking. The proposed methodology is employed on the Biotechnology industry in the period 2007-2010.
Abstract: In today's world where everything is rapidly changing
and information technology is high in development, many features of culture, society, politic and economy has changed. The advent of
information technology and electronic data transmission lead to easy communication and fields like e-learning and e-commerce, are
accessible for everyone easily. One of these technologies is virtual
training. The "quality" of such kind of education systems is critical. 131 questionnaires were prepared and distributed among university
student in Toba University. So the research has followed factors that affect the quality of learning from the perspective of staff, students, professors and this type of university. It is concluded that the important factors in virtual training are the quality of professors, the
quality of staff, and the quality of the university. These mentioned factors were the most prior factors in this education system and
necessary for improving virtual training.
Abstract: A key requirement for e-learning materials is
reusability and interoperability, that is the possibility to use at least
part of the contents in different courses, and to deliver them trough
different platforms. These features make possible to limit the cost of
new packages, but require the development of material according to
proper specifications. SCORM (Sharable Content Object Reference
Model) is a set of guidelines suitable for this purpose. A specific
adaptation project has been started to make possible to reuse existing
materials. The paper describes the main characteristics of SCORM
specification, and the procedure used to modify the existing material.
Abstract: The object of this paper is to design and analyze a
proportional – integral (PI) control for positive output elementary
super lift Luo converter (POESLLC), which is the start-of-the-art
DC-DC converter. The positive output elementary super lift Luo
converter performs the voltage conversion from positive source
voltage to positive load voltage. This paper proposes a
development of PI control capable of providing the good static and
dynamic performance compared to proportional – integralderivative
(PID) controller. Using state space average method
derives the dynamic equations describing the positive output
elementary super lift luo converter and PI control is designed. The
simulation model of the positive output elementary super lift Luo
converter with its control circuit is implemented in
Matlab/Simulink. The PI control for positive output elementary
super lift Luo converter is tested for transient region, line changes,
load changes, steady state region and also for components
variations.
Abstract: In rapidly changing market environment, firms are investing a lot of time and resources into new product development (NPD) projects to make profit and to obtain competitive advantage. However, failure rate of NPD projects is becoming high due to various internal and external risks which hinder successful NPD projects. To reduce the failure rate, it is critical that risks have to be managed effectively and efficiently through good strategy, and treated by optimal responses to minimize risk cost. Four strategies are adopted to handle the risks in this study. The optimal responses are characterized by high reduction of risk costs with high efficiency. This study suggests a framework to decide the optimal responses considering the core risks, risk costs, response efficiency and response costs for successful NPD projects. Both binary particles warm optimization (BPSO) and multi-objective particle swarm optimization (MOPSO) methods are mainly used in the framework. Although several limitations exist in use for real industries, the frame work shows good strength for handling the risks with highly scientific ways through an example.