Abstract: The present study was done primarily to address two major research gaps: firstly, development of an empirical measure of life meaningfulness for substance users and secondly, to determine the psychosocial determinants of life meaningfulness among the substance users. The study is classified into two phases: the first phase which dealt with development of Life Meaningfulness Scale and the second phase which examined the relationship between life meaningfulness and social support, abstinence self efficacy and depression. Both qualitative and quantitative approaches were used for framing items. A Principal Component Analysis yielded three components: Overall Goal Directedness, Striving for healthy lifestyle and Concern for loved ones which collectively accounted for 42.06% of the total variance. The scale and its subscales were also found to be highly reliable. Multiple regression analyses in the second phase of the study revealed that social support and abstinence self efficacy significantly predicted life meaningfulness among 48 recovering inmates of a de-addiction center while level of depression failed to predict life meaningfulness.
Abstract: Erroneous computer entry problems [here: 'e'errors] in hospital labs threaten the patients-–health carers- relationship, undermining the health system credibility. Are e-errors random, and do lab professionals make them accidentally, or may they be traced through meaningful determinants? Theories on internal causality of mistakes compel to seek specific causal ascriptions of hospital lab eerrors instead of accepting some inescapability. Undeniably, 'To Err is Human'. But in view of rapid global health organizational changes, e-errors are too expensive to lack in-depth considerations. Yet, that efunction might supposedly be entrenched in the health carers- job description remains under dispute – at least for Hellenic labs, where e-use falls behind generalized(able) appreciation and application. In this study: i) an empirical basis of a truly high annual cost of e-errors at about €498,000.00 per rural Hellenic hospital was established, hence interest in exploring the issue was sufficiently substantiated; ii) a sample of 270 lab-expert nurses, technicians and doctors were assessed on several personality, burnout and e-error measures, and iii) the hypothesis that the Hardiness vs Alienation personality construct disposition explains resistance vs proclivity to e-errors was tested and verified: Hardiness operates as a resilience source in the encounter of high pressures experienced in the hospital lab, whereas its 'opposite', i.e., Alienation, functions as a predictor, not only of making e-errors, but also of leading to burn-out. Implications for apt interventions are discussed.
Abstract: Stick models are widely used in studying the
behaviour of straight as well as skew bridges and viaducts subjected
to earthquakes while carrying out preliminary studies. The
application of such models to highly curved bridges continues to
pose challenging problems. A viaduct proposed in the foothills of the
Himalayas in Northern India is chosen for the study. It is having 8
simply supported spans @ 30 m c/c. It is doubly curved in horizontal
plane with 20 m radius. It is inclined in vertical plane as well. The
superstructure consists of a box section. Three models have been
used: a conventional stick model, an improved stick model and a 3D
finite element model. The improved stick model is employed by
making use of body constraints in order to study its capabilities. The
first 8 frequencies are about 9.71% away in the latter two models.
Later the difference increases to 80% in 50th mode. The viaduct was
subjected to all three components of the El Centro earthquake of May
1940. The numerical integration was carried out using the Hilber-
Hughes-Taylor method as implemented in SAP2000. Axial forces
and moments in the bridge piers as well as lateral displacements at
the bearing levels are compared for the three models. The maximum
difference in the axial forces and bending moments and
displacements vary by 25% between the improved and finite element
model. Whereas, the maximum difference in the axial forces,
moments, and displacements in various sections vary by 35%
between the improved stick model and equivalent straight stick
model. The difference for torsional moment was as high as 75%. It is
concluded that the stick model with body constraints to model the
bearings and expansion joints is not desirable in very sharp S curved
viaducts even for preliminary analysis. This model can be used only
to determine first 10 frequency and mode shapes but not for member
forces. A 3D finite element analysis must be carried out for
meaningful results.
Abstract: The PAX6, a transcription factor, is essential for the morphogenesis of the eyes, brain, pituitary and pancreatic islets. In rodents, the loss of Pax6 function leads to central nervous system defects, anophthalmia, and nasal hypoplasia. The haplo-insufficiency of Pax6 causes microphthalmia, aggression and other behavioral abnormalities. It is also required in brain patterning and neuronal plasticity. In human, heterozygous mutation of Pax6 causes loss of iris [aniridia], mental retardation and glucose intolerance. The 3- deletion in Pax6 leads to autism and aniridia. The phenotypes are variable in peneterance and expressivity. However, mechanism of function and interaction of PAX6 with other proteins during development and associated disease are not clear. It is intended to explore interactors of PAX6 to elucidated biology of PAX6 function in the tissues where it is expressed and also in the central regulatory pathway. This report describes In-silico approaches to explore interacting proteins of PAX6. The models show several possible proteins interacting with PAX6 like MITF, SIX3, SOX2, SOX3, IPO13, TRIM, and OGT. Since the Pax6 is a critical transcriptional regulator and master control gene of eye and brain development it might be interacting with other protein involved in morphogenesis [TGIF, TGF, Ras etc]. It is also presumed that matricelluar proteins [SPARC, thrombospondin-1 and osteonectin etc] are likely to interact during transport and processing of PAX6 and are somewhere its cascade. The proteins involved in cell survival and cell proliferation can also not be ignored.
Abstract: As part of national epidemiological survey on bovine
viral diarrhea virus (BVDV), a total of 274 dejecta samples were
collected from 14 cattle farms in 8 areas of Xinjiang Uygur
Autonomous Region in northwestern China. Total RNA was extracted
from each sample, and 5--untranslated region (UTR) of BVDV
genome was amplified by using two-step reverse
transcriptase-polymerase chain reaction (RT-PCR). The PCR products
were subsequently sequenced to study the genetic variations of BVDV
in these areas. Among the 274 samples, 33 samples were found
virus-positive. According to sequence analysis of the PCR products,
the 33 samples could be arranged into 16 groups. All the sequences,
however, were highly conserved with BVDV Osloss strains. The virus
possessed theses sequences belonged to BVDV-1b subtype by
phylogenetic analysis. Based on these data, we established a typing
tree for BVDV in these areas. Our results suggested that BVDV-1b
was a predominant subgenotype in northwestern China and no
correlation between the genetic and geographical distances could be
observed above the farm level.
Abstract: Three alumina-supported Pt-Sn catalysts have been
prepared by means of co-impregnation and characterized by XRD and
N2 adsorption. The influence of catalyst composition and reaction
conditions on the conversion and selectivity were investigated in the
hydrogenation of acetic acid in an isothermal integral fixed bed
reactor. The experiments were performed on the temperature interval
468-548 K, liquid hourly space velocity (LHSV) of 0.3-0.7h-1,
pressures between 1.0 and 5.0Mpa. A good compromise of
0.75%Pt-1.5%Sn can act as an optimized acetic acid hydrogenation
catalyst, and the conversion and selectivity can be tuned through the
variation of reaction conditions.
Abstract: The extraction of meaningful information from image
could be an alternative method for time series analysis. In this paper,
we propose a graphical analysis of time series grouped into table
with adjusted colour scale for numerical values. The advantages of
this method are also discussed. The proposed method is easy to
understand and is flexible to implement the standard methods of
pattern recognition and verification, especially for noisy
environmental data.
Abstract: Recently, neural networks have shown good
results for detection of a certain pattern in a given image. In
our previous papers [1-5], a fast algorithm for pattern
detection using neural networks was presented. Such
algorithm was designed based on cross correlation in the
frequency domain between the input image and the weights
of neural networks. Image conversion into symmetric shape
was established so that fast neural networks can give the
same results as conventional neural networks. Another
configuration of symmetry was suggested in [3,4] to improve
the speed up ratio. In this paper, our previous algorithm for
fast neural networks is developed. The frequency domain
cross correlation is modified in order to compensate for the
symmetric condition which is required by the input image.
Two new ideas are introduced to modify the cross correlation
algorithm. Both methods accelerate the speed of the fast
neural networks as there is no need for converting the input
image into symmetric one as previous. Theoretical and
practical results show that both approaches provide faster
speed up ratio than the previous algorithm.
Abstract: Many-core GPUs provide high computing ability and
substantial bandwidth; however, optimizing irregular applications
like SpMV on GPUs becomes a difficult but meaningful task. In this
paper, we propose a novel method to improve the performance of
SpMV on GPUs. A new storage format called HYB-R is proposed to
exploit GPU architecture more efficiently. The COO portion of the
matrix is partitioned recursively into a ELL portion and a COO
portion in the process of creating HYB-R format to ensure that there
are as many non-zeros as possible in ELL format. The method of
partitioning the matrix is an important problem for HYB-R kernel, so
we also try to tune the parameters to partition the matrix for higher
performance. Experimental results show that our method can get
better performance than the fastest kernel (HYB) in NVIDIA-s
SpMV library with as high as 17% speedup.
Abstract: EPA (Ethernet for Plant Automation) resolves the nondeterministic problem of standard Ethernet and accomplishes real-time communication by means of micro-segment topology and deterministic scheduling mechanism. This paper studies the real-time performance of EPA periodic data transmission from theoretical and experimental perspective. By analyzing information transmission characteristics and EPA deterministic scheduling mechanism, 5 indicators including delivery time, time synchronization accuracy, data-sending time offset accuracy, utilization percentage of configured timeslice and non-RTE bandwidth that can be used to specify the real-time performance of EPA periodic data transmission are presented and investigated. On this basis, the test principles and test methods of the indicators are respectively studied and some formulas for real-time performance of EPA system are derived. Furthermore, an experiment platform is developed to test the indicators of EPA periodic data transmission in a micro-segment. According to the analysis and the experiment, the methods to improve the real-time performance of EPA periodic data transmission including optimizing network structure, studying self-adaptive adjustment method of timeslice and providing data-sending time offset accuracy for configuration are proposed.
Abstract: Obesity is frequent attendant phenomenon of patients
with endocrinological disease. Between BMI and endocrinological
diseases is close correlation. In thesis we focused on the allocation of
hormone concentration – PTH and TSH, CHOL a mineral element Ca
in a blood serum. The examined group was formed by 100
respondents (women) aged 36 – 83 years, who were divided into two
groups – control group (CG), group with diagnosed endocrine disease
(DED). The concentration of PTH and TSH, Ca and CHOL was
measured through the medium of analyzers Cobas e411 (Japan);
Cobas Integra 400 (Switzerland). At individuals was measured body
weight as well as stature and thereupon from those data we
enumerated BMI. On the basis of Student T-test in biochemical
parameter of PTH and Ca we found out significantly meaningful
difference (p
Abstract: In the era of great competition, understanding and satisfying
customers- requirements are the critical tasks for a company
to make a profits. Customer relationship management (CRM) thus
becomes an important business issue at present. With the help of
the data mining techniques, the manager can explore and analyze
from a large quantity of data to discover meaningful patterns and
rules. Among all methods, well-known association rule is most
commonly seen. This paper is based on Apriori algorithm and uses
genetic algorithms combining a data mining method to discover fuzzy
classification rules. The mined results can be applied in CRM to
help decision marker make correct business decisions for marketing
strategies.
Abstract: Teaching and learning about sustainability is a pedagogical endeavour with various innate difficulties and increased demands. Higher education has a dual role to play in addressing this challenge: to identify and explore innovative approaches and tools for addressing the complex and value-laden nature of sustainability in more meaningful ways, and to help teachers to integrate these approaches into their practice through appropriate professional development programs. The study reported here was designed and carried out within the context of a Masters course in Environmental Education. Eight teachers were collaboratively engaged in reconstructing a digital game microworld which was deliberately designed by the researchers to be questioned and evoke critical discussion on the idea of ‘sustainable city’. The study was based on the design-based research method. The findings indicate that the teachers’ involvement in processes of co-constructing the microworld initiated discussion and reflection upon the concepts of sustainability and sustainable lifestyles.
Abstract: The goal of this research is discovering the
determinants of the success or failure of external cooperation in small
and medium enterprises (SMEs). For this, a survey was given to 190
SMEs that experienced external cooperation within the last 3 years. A
logistic regression model was used to derive organizational or strategic
characteristics that significantly influence whether external
collaboration of domestic SMEs is successful or not. Results suggest
that research and development (R&D) features in general
characteristics (both idea creation and discovering market
opportunities) that focused on and emphasized indirected-market
stakeholders (such as complementary companies and affiliates) and
strategies in innovative strategic characteristics raise the probability of
successful external cooperation. This can be used meaningfully to
build a policy or strategy for inducing successful external cooperation
or to understand the innovation of SMEs.
Abstract: Ontology is widely being used as a tool for organizing
information, creating the relation between the subjects within the
defined knowledge domain area. Various fields such as Civil,
Biology, and Management have successful integrated ontology in
decision support systems for managing domain knowledge and to
assist their decision makers. Gross pollutant traps (GPT) are devices
used in trapping and preventing large items or hazardous particles in
polluting and entering our waterways. However choosing and
determining GPT is a challenge in Malaysia as there are inadequate
GPT data repositories being captured and shared. Hence ontology is
needed to capture, organize and represent this knowledge into
meaningful information which can be contributed to the efficiency of
GPT selection in Malaysia urbanization. A GPT Ontology framework
is therefore built as the first step to capture GPT knowledge which
will then be integrated into the decision support system. This paper
will provide several examples of the GPT ontology, and explain how
it is constructed by using the Protégé tool.
Abstract: Subjective loneliness describes people who feel a
disagreeable or unacceptable lack of meaningful social relationships,
both at the quantitative and qualitative level. The studies to be
presented tested an Italian 18-items self-report loneliness measure,
that included items adapted from scales previously developed,
namely a short version of the UCLA (Russell, Peplau and Cutrona,
1980), and the 11-items Loneliness scale by De Jong-Gierveld &
Kamphuis (JGLS; 1985). The studies aimed at testing the developed
scale and at verifying whether loneliness is better conceptualized as a
unidimensional (so-called 'general loneliness') or a bidimensional
construct, namely comprising the distinct facets of social and
emotional loneliness. The loneliness questionnaire included 2 singleitem
criterion measures of sad mood, and social contact, and asked
participants to supply information on a number of socio-demographic
variables. Factorial analyses of responses obtained in two
preliminary studies, with 59 and 143 Italian participants respectively,
showed good factor loadings and subscale reliability and confirmed
that perceived loneliness has clearly two components, a social and an
emotional one, the latter measured by two subscales, a 7-item
'general' loneliness subscale derived from UCLA, and a 6–item
'emotional' scale included in the JGLS. Results further showed that
type and amount of loneliness are related, negatively, to frequency of
social contacts, and, positively, to sad mood. In a third study data
were obtained from a nation-wide sample of 9.097 Italian subjects,
12 to about 70 year-olds, who filled the test on-line, on the Italian
web site of a large-audience magazine, Focus. The results again
confirmed the reliability of the component subscales, namely social,
emotional, and 'general' loneliness, and showed that they were
highly correlated with each other, especially the latter two.
Loneliness scores were significantly predicted by sex, age, education
level, sad mood and social contact, and, less so, by other variables –
e.g., geographical area and profession. The scale validity was
confirmed by the results of a fourth study, with elderly men and
women (N 105) living at home or in residential care units. The three
subscales were significantly related, among others, to depression, and
to various measures of the extension of, and satisfaction with, social
contacts with relatives and friends. Finally, a fifth study with 315
career-starters showed that social and emotional loneliness correlate
with life satisfaction, and with measures of emotional intelligence.
Altogether the results showed a good validity and reliability in the
tested samples of the entire scale, and of its components.
Abstract: Highly pathogenic avian influenza (HPAI) H5N1 viruses have created demand for a cost-effective vaccine to prevent a pandemic of the disease. Here, we report that Trichoplusia ni (T. ni) larvae can act as a cost-effective bioreactor to produce recombinant HA5 (rH5HA) proteins as an potential effective vaccine for chickens. To facilitate the recombinant virus identification, virus titer determination and access the infected larvae, we employed the internal ribosome entry site (IRES) derived from Perina nuda virus (PnV, belongs to insect picorna like Iflavirus genus) to construct a bi-cistronic baculovirus expression vector that can express the rH5HA protein and enhanced green fluorescent protein (EGFP) simultaneously. Western blot analysis revealed that the 70 kDa rH5HA protein and partially cleaved products (40 kDa H5HA1) were generated in T. ni larvae infected with recombinant baculovirus carrying the H5HA gene. These data suggest that the baculovirus-larvae recombinant protein expression system could be a cost-effective platform for H5N1 vaccine production.
Abstract: Training with Functional Electrical Stimulation (FES)
has both physiological and psychological benefits for spinal cord
injured subjects. Commonly used methods for quantification of
spasticity have shown controversial reliability. In this study we
propose a method for quick determination of spasticity in spinal cord
injured subjects on a cycling and measurement system. 23 patients
did training sessions on an instrumented mobile FES cycle three
times a week over two months as part of their clinical rehabilitation
program. Spasticity (MAS) and the legs resistance to the pedaling
motion were assessed before and after the FES training and
measurements were done on the subjects ability to pedal with our
without motor assistance. Measurements with test persons with
incomplete spastic paraplegia have shown that spasticity is decreased
after a 30 min cycling training with functional electrical stimulation
(FES).
Abstract: This paper propose the robust character segmentation method for license plate with topological transform such as twist,rotation. The first step of the proposed method is to find a candidate region for character and license plate. The character or license plate
must be appeared as closed loop in the edge image. In the case of
detecting candidate for character region, the evaluation of detected
region is using topological relationship between each character. When
this method decides license plate candidate region, character features
in the region with binarization are used. After binarization for the detected candidate region, each character region is decided again. In
this step, each character region is fitted more than previous step. In the
next step, the method checks other character regions with different
scale near the detected character regions, because most license plates
have license numbers with some meaningful characters around them.
The method uses perspective projection for geometrical normalization.
If there is topological distortion in the character region, the method
projects the region on a template which is defined as standard license
plate using perspective projection. In this step, the method is able to
separate each number region and small meaningful characters. The
evaluation results are tested with a number of test images.
Abstract: Increase in using internet makes some problems that
one of them is "internet anxiety". Internet anxiety is a type of anxious
that people may feel during surfing internet or using internet for their
educational purpose, blogging or streaming to digital libraries. The
goal of this study is evaluating of internet anxiety among the
management students. In this research Ealy's internet anxiety
questionnaire, consists of positive and negative items, is completed
by 310 participants. According to the findings, about 64.7% of them
were equal or below to mean anxiety score (50). The distribution of
internet anxiety scores was normal and there was no meaningful
difference between men-s and women's anxiety level in this sample.
Results also showed that there is no meaningful difference of internet
anxiety level between different fields of study in Management. This
evaluation will help managers to perform gap analysis between the
existent level and the desired one. Future work would be providing
techniques for abating human anxiety while using internet via human
computer interaction techniques.