Abstract: The application of cold Radio-Frequency (RF) plasma
in the conservation of cultural heritage became important in the last
decades due to the positive results obtained in decontamination
treatments. This paper presents an equipment especially designed for cold RF
plasma application on paper documents, developed within a research
project. The equipment consists in two modules: the first one is
designed for decontamination and cleaning treatments of any type of
paper supports, while the second one can be used for coating friable
papers with adequate polymers, for protection purposes. All these
operations are carried out in cold radio-frequency plasma, working in
gaseous nitrogen, at low pressure. In order to optimize the equipment parameters ancient paper
samples infested with microorganisms have been treated in nitrogen
plasma and the decontamination effects, as well as changes in surface
properties (color, pH) were assessed. The microbiological analysis
revealed complete decontamination at 6 minutes treatment duration;
only minor modifications of the surface pH were found and the
colorimetric analysis showed a slight yellowing of the support.
Abstract: Objective: Sharing devastating news with patients is
often considered the most difficult task of doctors. This study aimed
to explore patients’ perceptions of receiving bad news including
which features improve the experience and which areas need refining. Methods: A questionnaire was written based on the steps of the
SPIKES model for breaking bad new. 20 patients receiving treatment
for a hematological malignancy completed the questionnaire. Results: Overall, the results are promising as most patients praised
their consultation. ‘Poor’ was more commonly rated by women and
participants aged 45-64. The main differences between the ‘excellent’
and ‘poor’ consultations include the doctor’s sensitivity and checking
the patients’ understanding. Only 35% of patients were asked their
existing knowledge and 85% of consultations failed to discuss the
impact of the diagnosis on daily life. Conclusion: This study agreed with the consensus of existing
literature. The commended aspects include consultation set-up and
information given. Areas patients felt needed improvement include
doctors determining the patient’s existing knowledge and checking
new information has been understood. Doctors should also explore
how the diagnosis will affect the patient’s life. With a poorer
prognosis, doctors should work on conveying appropriate hope. The
study was limited by a small sample size and potential recall bias.
Abstract: Web mining is to discover and extract useful
Information. Different users may have different search goals when
they search by giving queries and submitting it to a search engine.
The inference and analysis of user search goals can be very useful for
providing an experience result for a user search query. In this project,
we propose a novel approach to infer user search goals by analyzing
search web logs. First, we propose a novel approach to infer user
search goals by analyzing search engine query logs, the feedback
sessions are constructed from user click-through logs and it
efficiently reflect the information needed for users. Second we
propose a preprocessing technique to clean the unnecessary data’s
from web log file (feedback session). Third we propose a technique
to generate pseudo-documents to representation of feedback sessions
for clustering. Finally we implement k-medoids clustering algorithm
to discover different user search goals and to provide a more optimal
result for a search query based on feedback sessions for the user.
Abstract: Numerous investigations suggest that Mesenchymal
Stem Cells (MSCs) in general represent a valuable tool for therapy of
symptoms related to chronic inflammatory diseases. Blue Horizon
Stem Cell Therapy Program is a leading provider of adult and
children’s stem cell therapies. Uniquely we have safely and
efficiently treated more than 600 patients with documenting each
procedure. The purpose of our study is primarily to monitor the
immune response in order to validate the safety of intravenous
infusion of human umbilical cord blood derived MSCs (UC-MSCs),
and secondly, to evaluate effects on biomarkers associated with
chronic inflammation. Nine patients were treated for conditions
associated with chronic inflammation and for the purpose of antiaging.
They have been given one intravenous infusion of UCMSCs.
Our study of blood test markers of 9 patients with chronic
inflammation before and within three months after MSCs treatment
demonstrates that there is no significant changes and MSCs treatment
was safe for the patients. Analysis of different indicators of chronic
inflammation and aging included in initial, 24-hours, two weeks and
three months protocols showed that stem cell treatment was safe for
the patients; there were no adverse reactions. Moreover data from
follow up protocols demonstrates significant improvement in energy
level, hair, nails growth and skin conditions. Intravenously
administered UC-MSCs were safe and effective in the improvement
of symptoms related to chronic inflammation. Further close
monitoring and inclusion of more patients are necessary to fully
characterize the advantages of UC-MSCs application in treatment of
symptoms related to chronic inflammation.
Abstract: This research paper presents the current practices of
teacher professional development, perceived as beneficial by teachers
themselves, in a private secondary school in Brunei Darussalam. This
is part of the findings of a larger qualitative study on teacher
empowerment, using ethnographic methods for data collection, i.e.
participant observation, interviews and document analysis. The field
work was carried out over a period of six months in 2013. An
analysis of the field data revealed multiple pathways of teacher
professional development existing in the school. The results indicate
that school leaders, the teacher community in the school, students,
and the teachers themselves were the agents in a school that
facilitated teacher empowerment. Besides contributing to the
knowledge base on teacher professional development, the results of
this study provide directions for educational policy makers in their
efforts to enhance professional development in secondary schools of
similar characteristics. For school leaders and the teacher community,
these findings offer guidelines for maximizing the opportunities for
these professional development practices, by strengthening
collegiality and by using the existing structures optimally for the
benefit of all concerned.
Abstract: The aim of this study is to investigate the relationship
between expectation, satisfaction and loyalty of South Korean
tourists visiting Turkey. In the research, a questionnaire was used as a
data collecting tool. The questionnaires are filled by South Korean
tourists coming to Turkey through package tours and individual. The
survey was conducted in 2014 in Nevsehir (Cappadocia Region) and
Istanbul. Tourist guides and agency staff have helped the
implementation of surveys. The survey questions are composed of 4
parts, which are “demographic characteristics of tourists”, “travel
behavior characteristics”, “perception of expectations on destination
attributes” and “perception of destination loyalty”. 5-point Likert
type scale including 28 destination attributes was used to measure the
expectations of South Korean tourists coming to Turkey. Questions
were directed to the tourists to measure the destination loyalty. The
questions relating to destination loyalty are “Talking about Turkey to
others”, “Recommendation Turkey to others” and “Tourists’
intentions to revisit Turkey”. The basic hypothesis of the research is
that there is a statistically significant relationship among
expectations, satisfactions and destination loyalty of South Korean
tourists coming to Turkey. The results indicated that the expectation
had a significant effect on overall satisfaction. In addition it was seen
that between overall satisfaction of tourists and destination loyalty
had a significant relationship. Based on findings, some suggestions
for tour operators and travel agencies were made.
Abstract: In this paper, we report the development of the device
for diagnostics of cardiovascular system state and associated
automated workstation for large-scale medical measurement data
collection and analysis. It was shown that optimal design for the
monitoring device is wristband as it represents engineering trade-off
between accuracy and usability. Monitoring device is based on the
infrared reflective photoplethysmographic sensor, which allows
collecting multiple physiological parameters, such as heart rate and
pulsing wave characteristics. Developed device uses BLE interface
for medical and supplementary data transmission to the coupled
mobile phone, which processes it and send it to the doctor's
automated workstation. Results of this experimental model
approbation confirmed the applicability of the proposed approach.
Abstract: Based on the hypothesis that disaster risk is
constructed socially and historically, this article shows the
importance of keeping alive the historical memory of disaster by
means of architectural and urban heritage conservation. This is
illustrated with three examples of Latin American World Heritage
cities, where disasters like floods and earthquakes have shaped urban
form. Therefore, the study of urban form or "Urban Morphology" is
proposed as a tool to understand and analyze urban transformations
with the documentation of the occurrence of disasters. Lessons
learned from such cities may be useful to reduce disasters risk in
contemporary built environments.
Abstract: The literature on language teaching and second
language acquisition has been largely driven by monolingual
ideology with a common assumption that a second language (L2) is
best taught and learned in the L2 only. The current study challenges
this assumption by reporting learners' positive perceptions of tertiary
level teachers' code switching practices in Vietnam. The findings of
this study contribute to our understanding of code switching practices
in language classrooms from a learners' perspective.
Data were collected from student participants who were working
towards a Bachelor degree in English within the English for Business
Communication stream through the use of focus group interviews.
The literature has documented that this method of interviewing has a
number of distinct advantages over individual student interviews. For
instance, group interactions generated by focus groups create a more
natural environment than that of an individual interview because they
include a range of communicative processes in which each individual
may influence or be influenced by others - as they are in their real
life. The process of interaction provides the opportunity to obtain the
meanings and answers to a problem that are "socially constructed
rather than individually created" leading to the capture of real-life
data. The distinct feature of group interaction offered by this
technique makes it a powerful means of obtaining deeper and richer
data than those from individual interviews. The data generated
through this study were analysed using a constant comparative
approach. Overall, the students expressed positive views of this
practice indicating that it is a useful teaching strategy. Teacher code
switching was seen as a learning resource and a source supporting
language output. This practice was perceived to promote student
comprehension and to aid the learning of content and target language
knowledge. This practice was also believed to scaffold the students'
language production in different contexts. However, the students
indicated their preference for teacher code switching to be
constrained, as extensive use was believed to negatively impact on
their L2 learning and trigger cognitive reliance on the L1 for L2
learning. The students also perceived that when the L1 was used to a
great extent, their ability to develop as autonomous learners was
negatively impacted.
This study found that teacher code switching was supported in
certain contexts by learners, thus suggesting that there is a need for
the widespread assumption about the monolingual teaching approach
to be re-considered.
Abstract: This study aims at developing a novel cold asphalt
concrete binder course mixture by using Ordinary Portland Cement
(OPC) as a replacement for conventional mineral filler (0%-100%)
with new by-product material (LJMU-A2) used as a supplementary
cementitious material. With this purpose, cold asphalt concrete binder
course mixtures with cationic emulsions were studied by means of
stiffness modulus whereas water sensitivity was assessed by
measuring the stiffness modulus ratio before and after sample
conditioning.
The results indicate that a substantial enhancement in the stiffness
modulus and a considerable improvement of water sensitivity
resistance is achieved by adding LJMU-A2 to the cold asphalt
mixtures as a supplementary cementitious material. Moreover, the
addition of LJMU-A2 to those mixtures leads to a stiffness modulus
after 2-day curing compared to that obtained with Portland cement,
which occurs after 7-day curing.
Abstract: This paper represents the results of experimental work to investigate the suitability of a waste material (WM) for soft soil stabilisation. In addition, the effect of particle size distribution (PSD) of the waste material on its performance as a soil stabiliser was investigated. The WM used in this study is produced from the incineration processes in domestic energy power plant and it is available in two different grades of fineness (coarse waste material (CWM) and fine waste material (FWM)). An intermediate plasticity silty clayey soil with medium organic matter content has been used in this study. The suitability of the CWM and FWM to improve the physical and engineering properties of the selected soil was evaluated dependant on the results obtained from the consistency limits, compaction characteristics (optimum moisture content (OMC) and maximum dry density (MDD)); along with the unconfined compressive strength test (UCS). Different percentages of CWM were added to the soft soil (3, 6, 9, 12 and 15%) to produce various admixtures. Then the UCS test was carried out on specimens under different curing periods (zero, 7, 14, and 28 days) to find the optimum percentage of CWM. The optimum and other two percentages (either side of the optimum content) were used for FWM to evaluate the effect of the fineness of the WM on UCS of the stabilised soil. Results indicated that both types of the WM used in this study improved the physical properties of the soft soil where the index of plasticity (IP) was decreased significantly. IP was decreased from 21 to 13.64 and 13.10 with 12% of CWM and 15% of FWM respectively. The results of the unconfined compressive strength test indicated that 12% of CWM was the optimum and this percentage developed the UCS value from 202kPa to 500kPa for 28 days cured samples, which is equal, approximately 2.5 times the UCS value for untreated soil. Moreover, this percentage provided 1.4 times the value of UCS for stabilized soil-CWA by using FWM which recorded just under 700kPa after 28 days curing.
Abstract: In this paper we propose a computer-aided solution
with Genetic Algorithms in order to reduce the drafting of reports:
FMEA analysis and Control Plan required in the manufacture of the
product launch and improved knowledge development teams for
future projects. The solution allows to the design team to introduce
data entry required to FMEA. The actual analysis is performed using
Genetic Algorithms to find optimum between RPN risk factor and
cost of production. A feature of Genetic Algorithms is that they are
used as a means of finding solutions for multi criteria optimization
problems. In our case, along with three specific FMEA risk factors is
considered and reduce production cost. Analysis tool will generate
final reports for all FMEA processes. The data obtained in FMEA
reports are automatically integrated with other entered parameters in
Control Plan. Implementation of the solution is in the form of an
application running in an intranet on two servers: one containing
analysis and plan generation engine and the other containing the
database where the initial parameters and results are stored. The
results can then be used as starting solutions in the synthesis of other
projects. The solution was applied to welding processes, laser cutting
and bending to manufacture chassis for buses. Advantages of the
solution are efficient elaboration of documents in the current project
by automatically generating reports FMEA and Control Plan using
multiple criteria optimization of production and build a solid
knowledge base for future projects. The solution which we propose is
a cheap alternative to other solutions on the market using Open
Source tools in implementation.
Abstract: The system for analyzing and eliciting public
grievances serves its main purpose to receive and process all sorts of
complaints from the public and respond to users. Due to the more
number of complaint data becomes big data which is difficult to store
and process. The proposed system uses HDFS to store the big data
and uses MapReduce to process the big data. The concept of cache
was applied in the system to provide immediate response and timely
action using big data analytics. Cache enabled big data increases the
response time of the system. The unstructured data provided by the
users are efficiently handled through map reduce algorithm. The
processing of complaints takes place in the order of the hierarchy of
the authority. The drawbacks of the traditional database system used
in the existing system are set forth by our system by using Cache
enabled Hadoop Distributed File System. MapReduce framework
codes have the possible to leak the sensitive data through
computation process. We propose a system that add noise to the
output of the reduce phase to avoid signaling the presence of
sensitive data. If the complaints are not processed in the ample time,
then automatically it is forwarded to the higher authority. Hence it
ensures assurance in processing. A copy of the filed complaint is sent
as a digitally signed PDF document to the user mail id which serves
as a proof. The system report serves to be an essential data while
making important decisions based on legislation.
Abstract: This article is to introduce the meaning and form of
social quality moving process as indicated by members of two suburb
communities with different social and cultural contexts. The form of
social quality moving process is very significant for the community
and social development, because it will make the people living
together with sustainable happiness.
This is a qualitative study involving 30 key-informants from two
suburb communities. Data were collected though key-informant
interviews, and analyzed using logical content description and
descriptive statistics.
This research found that on the social quality component, the
people in both communities stressed the procedure for social qualitymaking.
This includes the generousness, sharing and assisting among
people in the communities. These practices helped making people to
live together with sustainable happiness. Living as a family or appear
to be a family is the major social characteristic of these two
communities.
This research also found that form of social quality’s moving
process of both communities stress relation of human and nature;
“nature overpower humans” paradigm and influence of religious
doctrine that emphasizes relations among humans. Both criteria make
the form of social’s moving process simple, adaptive to nature and
caring for opinion sharing and understanding among each other
before action. This form of social quality’s moving process is
composed of 4 steps; (1) awareness building, (2) motivation to
change, (3) participation from every party which is concerned (4)
self-reliance.
Abstract: The US Consumer Price Indices (CPIs) measures
hundreds of items in the US economy. Many social programs
and government benefits index to the CPIs. The purpose of
this project is to modernize an existing process. This paper will
show the development of a small, visual, software product that
documents the Economic Price Adjustment (EPA) for longterm
contracts. The existing workbook does not provide the
flexibility to calculate EPAs where the base-month and the
option-month are different. Nor does the workbook provide
automated error checking. The small, visual, software product
provides the additional flexibility and error checking. This
paper presents the feedback to project.
Abstract: Plasmin plays an important role in the human
circulatory system owing to its catalytic ability of fibrinolysis. The
immediate injection of plasmin in patients of strokes has intrigued
many scientists to design vectors that can transport plasmin to the
desired location in human body. Here we predict the structure of
human plasmin and investigate the interaction of plasmin with the
gold-nanoparticle.
Because the crystal structure of plasminogen has been solved, we
deleted N-terminal domain (Pan-apple domain) of plasminogen and
generate a mimic of the active form of this enzyme (plasmin). We
conducted a simulated annealing process on plasmin and discovered a
very large conformation occurs. Kringle domains 1, 4 and 5 had been
observed to leave its original location relative to the main body of the
enzyme and the original doughnut shape of this enzyme has been
transformed to a V-shaped by opening its two arms. This observation
of conformational change is consistent with the experimental results of
neutron scattering and centrifugation.
We subsequently docked the plasmin on the simulated gold surface
to predict their interaction. The V-shaped plasmin could utilize its
Kringle domain and catalytic domain to contact the gold surface.
Our findings not only reveal the flexibility of plasmin structure but
also provide a guide for the design of a plasmin-gold nanoparticle.
Abstract: Purpose: The study aimed to assess the depressant or
antidepressant effects of several Nonsteroidal Anti-Inflammatory
Drugs (NSAIDs) in mice: the selective cyclooxygenase-2 (COX-2)
inhibitor meloxicam, and the non-selective COX-1 and COX-2
inhibitors lornoxicam, sodium metamizole, and ketorolac. The
current literature data regarding such effects of these agents are
scarce.
Materials and methods: The study was carried out on NMRI mice
weighing 20-35 g, kept in a standard laboratory environment. The
study was approved by the Ethics Committee of the University of
Medicine and Pharmacy „Carol Davila”, Bucharest. The study agents
were injected intraperitoneally, 10 mL/kg body weight (bw) 1 hour
before the assessment of the locomotor activity by cage testing (n=10
mice/ group) and 2 hours before the forced swimming tests (n=15).
The study agents were dissolved in normal saline (meloxicam,
sodium metamizole), ethanol 11.8% v/v in normal saline (ketorolac),
or water (lornoxicam), respectively. Negative and positive control
agents were also given (amitryptilline in the forced swimming test).
The cage floor used in the locomotor activity assessment was divided
into 20 equal 10 cm squares. The forced swimming test involved
partial immersion of the mice in cylinders (15/9cm height/diameter)
filled with water (10 cm depth at 28C), where they were left for 6
minutes. The cage endpoint used in the locomotor activity assessment
was the number of treaded squares. Four endpoints were used in the
forced swimming test (immobility latency for the entire 6 minutes,
and immobility, swimming, and climbing scores for the final 4
minutes of the swimming session), recorded by an observer that was
„blinded” to the experimental design. The statistical analysis used the
Levene test for variance homogeneity, ANOVA and post-hoc
analysis as appropriate, Tukey or Tamhane tests.
Results: No statistically significant increase or decrease in the
number of treaded squares was seen in the locomotor activity
assessment of any mice group. In the forced swimming test,
amitryptilline showed an antidepressant effect in each experiment, at
the 10 mg/kg bw dosage. Sodium metamizole was depressant at 100
mg/kg bw (increased the immobility score, p=0.049, Tamhane test),
but not in lower dosages as well (25 and 50 mg/kg bw). Ketorolac
showed an antidepressant effect at the intermediate dosage of 5
mg/kg bw, but not so in the dosages of 2.5 and 10 mg/kg bw,
respectively (increased the swimming score, p=0.012, Tamhane test).
Meloxicam and lornoxicam did not alter the forced swimming
endpoints at any dosage level.
Discussion: 1) Certain NSAIDs caused changes in the forced
swimming patterns without interfering with locomotion. 2) Sodium
metamizole showed a depressant effect, whereas ketorolac proved
antidepressant. Conclusion: NSAID-induced mood changes are not
class effects of these agents and apparently are independent of the
type of inhibited cyclooxygenase (COX-1 or COX-2).
Disclosure: This paper was co-financed from the European Social
Fund, through the Sectorial Operational Programme Human Resources Development 2007-2013, project number POSDRU /159
/1.5 /S /138907 "Excellence in scientific interdisciplinary research,
doctoral and postdoctoral, in the economic, social and medical fields
-EXCELIS", coordinator The Bucharest University of Economic
Studies.
Abstract: Phthalates are ubiquitous environmental pollutants
well known because of their endocrine disrupting activity in human
organism. The aim of our study was, by biological monitoring,
investigate exposure to phthalates of Roma ethnicity group i.e.
children and adults from 5 families (n=29, average age 11.8 ± 7.6
years) living in western Slovakia. Additionally, we analysed some
associations between anthropometric measures, questionnaire data
i.e. socio-economic status, eating and drinking habits, practise of
personal care products and household conditions in comparison with
concentrations of phthalate metabolites. We used for analysis of urine
samples high performance liquid chromatography and tandem mass
spectrometry (HPLC-MS/MS) to determine concentrations of
phthalate metabolites monoethyl phthalate (MEP), mono-n-butyl
phthalate (MnBP), mono-iso-butyl phthalate (MiBP), mono(2-ethyl-
5-hydroxyhexyl) phthalate (5OH-MEHP), mono(2-ethyl-5-oxohexyl)
phthalate (5oxo-MEHP) and mono(2-etylhexyl) phthalate (MEHP).
Our results indicate that ethnicity, lower socioeconomic status and
different housing conditions in Roma population can affect urinary
concentration of phthalate metabolites.
Abstract: The growth in the volume of text data such as books
and articles in libraries for centuries has imposed to establish
effective mechanisms to locate them. Early techniques such as
abstraction, indexing and the use of classification categories have
marked the birth of a new field of research called "Information
Retrieval". Information Retrieval (IR) can be defined as the task of
defining models and systems whose purpose is to facilitate access to
a set of documents in electronic form (corpus) to allow a user to find
the relevant ones for him, that is to say, the contents which matches
with the information needs of the user. This paper presents a new
semantic indexing approach of a documentary corpus. The indexing
process starts first by a term weighting phase to determine the
importance of these terms in the documents. Then the use of a
thesaurus like Wordnet allows moving to the conceptual level.
Each candidate concept is evaluated by determining its level of
representation of the document, that is to say, the importance of the
concept in relation to other concepts of the document. Finally, the
semantic index is constructed by attaching to each concept of the
ontology, the documents of the corpus in which these concepts are
found.
Abstract: Breast cancer is considered as a substantial health
concern and practicing mammography screening [MS] is important in
minimizing its related morbidity. So it is essential to have a better
understanding of breast cancer screening behaviors of women and
factors that influence utilization of them. The aim of this study is to
identify the factors that are linked to MS behaviors among the
Egyptian women. A cross-sectional descriptive design was carried
out to provide a snapshot of the factors that are linked to MS
behaviors. A convenience sample of 311 women was utilized and all
eligible participants admitted to the Women Imaging Unit who are 40
years of age or above, coming for mammography assessment, not
pregnant or breast feeding and who accepted to participate in the
study were included. A structured questionnaire was developed by
the researchers and contains three parts; Socio-demographic data;
Motivating factors associated with MS; and association between MS
and model of behavior change. The analyzed data indicated that most
of the participated women (66.6%) belonged to the age group of 40-
49.A high proportion of participants (58.1%) of group having
previous MS influenced by their neighbors to practice MS, whereas
32.7 % in group not having previous MS were influenced by family
members which indicated significant differences (P