Abstract: Hyperglycemia-mediated accumulation of advanced glycation end-products (AGEs) play a pivotal role in the development of diabetic complications by inducing inflammation. In the present study, we evaluated the possible effects of water/ethanol (1/1, v/v) extracts (WEE) and its fractions from Canarium album Raeusch. (Chinese olive) which is a fruit used on AGEs-stimulated oxidative stress and inflammation in monocytes and vascular endothelial cells. Co-incubation of EA.hy926 endothelial cells with WEE and its fractions for 24h resulted in a significant decrease of monocyte–endothelial cell adhesion, the expression of ICAM-1, generation of intracellular ROS and depletion of GSH induced by AGEs. Chinese olive fruit extracts also reduced the expression of pro-inflammatory mediates, such as TNF-α, IL-1β and IL-6 in THP-1 cells. These findings suggested that Chinese olive fruit was able to protect vascular endothelium from dysfunction induced by AGEs.
Abstract: Study on suppression of interference in time domain equalizers is attempted for high data rate impulse radio (IR) ultra wideband communication system. The narrow band systems may cause interference with UWB devices as it is having very low transmission power and the large bandwidth. SRAKE receiver improves system performance by equalizing signals from different paths. This enables the use of SRAKE receiver techniques in IRUWB systems. But Rake receiver alone fails to suppress narrowband interference (NBI). A hybrid SRake-MMSE time domain equalizer is proposed to overcome this by taking into account both the effect of the number of rake fingers and equalizer taps. It also combats intersymbol interference. A semi analytical approach and Monte-Carlo simulation are used to investigate the BER performance of SRAKEMMSE receiver on IEEE 802.15.3a UWB channel models. Study on non-line of sight indoor channel models (both CM3 and CM4) illustrates that bit error rate performance of SRake-MMSE receiver with NBI performs better than that of Rake receiver without NBI. We show that for a MMSE equalizer operating at high SNR-s the number of equalizer taps plays a more significant role in suppressing interference.
Abstract: This paper presents a new version of the SVM mixture algorithm initially proposed by Kwok for classification and regression problems. For both cases, a slight modification of the mixture model leads to a standard SVM training problem, to the existence of an exact solution and allows the direct use of well known decomposition and working set selection algorithms. Only the regression case is considered in this paper but classification has been addressed in a very similar way. This method has been successfully applied to engine pollutants emission modeling.
Abstract: Populations of wild boar present in semi-arid of central Iran. We studied features influencing bed site selection by this species in semi-arid central steppe of Iran. Habitat features of the detected bed site were compared with randomly selected by quantifying number of habitat variables in semi- arid area in Iran. The results revealed that the most important influencing factors in bed site selection were vegetation cover, number of Artemisia sieberi, percentage cover and height of Acer cinerascens, percentage cover and height of Amygdalus scoparia. This is the first ecological study of the wild boar in a protected area of the semi desert biome of Iran. Sustainability of wild boar populations in this area dependent to shrubs of Amygdalus scoparia and Acer cinerascens for thermal and camouflage cover.
Abstract: Due to a high unemployment rate among local people
and a high reliance on expatriate workers, the governments in the
Gulf Co-operation Council (GCC) countries have been implementing
programmes of localisation (replacing foreign workers with GCC
nationals). These programmes have been successful in the public
sector but much less so in the private sector. However, there are now
insufficient jobs for locals in the public sector and the onus to provide
employment has fallen on the private sector. This paper is concerned
with a study, which is a work in progress (certain elements are
complete but not the whole study), investigating the effective
implementation of localisation policies in four- and five-star hotels in
the Kingdom of Saudi Arabia (KSA) and the United Arab Emirates
(UAE). The purpose of the paper is to identify the research gap, and
to present the need for the research. Further, it will explain how this
research was conducted.
Studies of localisation in the GCC countries are under-represented
in scholarly literature. Currently, the hotel sectors in KSA and UAE
play an important part in the countries’ economies. However, the
total proportion of Saudis working in the hotel sector in KSA is
slightly under 8%, and in the UAE, the hotel sector remains highly
reliant on expatriates. There is therefore a need for research on
strategies to enhance the implementation of the localisation policies
in general and in the hotel sector in particular.
Further, despite the importance of the hotel sector to their
economies, there remains a dearth of research into the
implementation of localisation policies in this sector. Indeed, as far as
the researchers are aware, there is no study examining localisation in
the hotel sector in KSA, and few in the UAE. This represents a
considerable research gap.
Regarding how the research was carried out, a multiple case study
strategy was used. The four- and five-star hotel sector in KSA is one
of the cases, while the four- and five-star hotel sector in the UAE is
the other case. Four- and five-star hotels in KSA and the UAE were
chosen as these countries have the longest established localisation
policies of all the GCC states and there are more hotels of these
classifications in these countries than in any of the other Gulf
countries. A literature review was carried out to underpin the
research. The empirical data were gathered in three phases. In order
to gain a pre-understanding of the issues pertaining to the research
context, Phase I involved eight unstructured interviews with officials
from the Saudi Commission for Tourism and Antiquities (three
interviewees); the Saudi Human Resources Development Fund (one);
the Abu Dhabi Tourism and Culture Authority (three); and the Abu
Dhabi Development Fund (one).
In Phase II, a questionnaire was administered to 24 managers and
24 employees in four- and five-star hotels in each country to obtain
their beliefs, attitudes, opinions, preferences and practices concerning
localisation.
Unstructured interviews were carried out in Phase III with six
managers in each country in order to allow them to express opinions
that may not have been explored in sufficient depth in the
questionnaire. The interviews in Phases I and III were analysed using
thematic analysis and SPSS will be used to analyse the questionnaire
data.
It is recommended that future research be undertaken on a larger
scale, with a larger sample taken from all over KSA and the UAE
rather than from only four cities (i.e., Riyadh and Jeddah in KSA and
Abu Dhabi and Sharjah in the UAE), as was the case in this research.
Abstract: The aim of this paper is to continue the study of ( T1, T 2)-semi star generalized closed sets by introducing the concepts of (T 1, T 2)-semi star generalized locally closed sets and study their basic properties in bitopological spaces.
Abstract: Design for cost (DFC) is a method that reduces life
cycle cost (LCC) from the angle of designers. Multiple domain
features mapping (MDFM) methodology was given in DFC. Using
MDFM, we can use design features to estimate the LCC. From the
angle of DFC, the design features of family cars were obtained, such
as all dimensions, engine power and emission volume. At the
conceptual design stage, cars- LCC were estimated using back
propagation (BP) artificial neural networks (ANN) method and
case-based reasoning (CBR). Hamming space was used to measure the
similarity among cases in CBR method. Levenberg-Marquardt (LM)
algorithm and genetic algorithm (GA) were used in ANN. The
differences of LCC estimation model between CBR and artificial
neural networks (ANN) were provided. ANN and CBR separately
each method has its shortcomings. By combining ANN and CBR
improved results accuracy was obtained. Firstly, using ANN selected
some design features that affect LCC. Then using LCC estimation
results of ANN could raise the accuracy of LCC estimation in CBR
method. Thirdly, using ANN estimate LCC errors and correct errors in
CBR-s estimation results if the accuracy is not enough accurate.
Finally, economically family cars and sport utility vehicle (SUV) was
given as LCC estimation cases using this hybrid approach combining
ANN and CBR.
Abstract: This study deals with the experimental investigation
and theoretical modeling of Semi crystalline polymeric materials with
a rubbery amorphous phase (HDPE) subjected to a uniaxial cyclic
tests with various maximum strain levels, even at large deformation.
Each cycle is loaded in tension up to certain maximum strain and
then unloaded down to zero stress with N number of cycles. This
work is focuses on the measure of the volume strain due to the
phenomena of damage during this kind of tests. On the basis of
thermodynamics of relaxation processes, a constitutive model for
large strain deformation has been developed, taking into account the
damage effect, to predict the complex elasto-viscoelastic-viscoplastic
behavior of material. A direct comparison between the model
predictions and the experimental data show that the model accurately
captures the material response. The model is also capable of
predicting the influence damage causing volume variation.
Abstract: Recent studies demonstrated that high-fat diet increases oxidative stress in plasma and in a variety of tissues. Many researchers have been looking for natural products, which can reverse the effect of high fat diet. Recently, buckwheat is becoming common ingredient in functional food because of it properties. In study on buckwheat, it is known that, this plant plays roles as anti-oxidative, anti-inflammatory and anti-hypertensive. Nevertheless still little is known about buckwheat groats. The aim of this study was to investigate the effects of addition of buckwheat groats to the fat diet (30% lard), on some antioxidant and oxidant stress parameters in plasma and selected tissues in Wistar rats. The experiment was carried out with three months old male Wistar rats ca. 250g of body weight fed for 5 weeks with either a high-fat (30% of lard) diet or control diet, with or without addition of buckwheat groats. In plasma biochemistry and the activities of the antioxidant enzymes were measured selected tissues: glutathione peroxidase (GPX), catalase (CAT) and the levels of total and reduced glutathione (GSH), free thiol groups (pSH), antioxidant potential of plasma (FRAP) and oxidant stress indices - proteins carbonyl groups (CO) and malonyldialdehyde concentration (MDA). Activity of catalase (CAT) in plasma of rats was significantly increased in buckwheat groats groups and activity of GPx3 in plasma of rats was decreased in buckwheat groups as compared to control group. The reduced glutathione (GSH) in plasma of rats was significantly increased and protein CO was significantly decreased in buckwheat groups as compared to controls. The lowered concentration of GSH was found in serum of rats fed buckwheat groats addition but it accompanied in 7-fold increase in reduced-to-oxidized glutatione ratio, significant increase in HDL and decrease in nonHDL concentration. Conclusions: Buckwheat groats indicate a beneficial effect in inhibiting protein and lipid peroxidation in rats and improved lipid profile. These results suggest that buckwheat groats exert a significant antioxidant potential and may be used as normal food constituent to ameliorate the oxidant-induced damage in organism.
Abstract: Neonatal lupus erythematous (NLE) is a rare disease marked by clinical characteristic and specific maternal autoantibody. Many cutaneous, cardiac, liver, and hematological manifestations could happen with affect of one organ or multiple. In this case, both babies were premature, low birth weight (LBW), small for gestational age (SGA) and born through caesarean section from a systemic lupus erythematous (SLE) mother. In the first case, we found a baby girl with dyspnea and grunting. Chest X ray showed respiratory distress syndrome (RDS) great I and echocardiography showed small atrial septal defect (ASD) and ventricular septal defect (VSD). She also developed anemia, thrombocytopenia, elevated C-reactive protein, hypoalbuminemia, increasing coagulation factors, hyperbilirubinemia, and positive blood culture of Klebsiella pneumonia. Anti-Ro/SSA and Anti-nRNP/sm were positive. Intravenous fluid, antibiotic, transfusion of blood, thrombocyte concentrate, and fresh frozen plasma were given. The second baby, male presented with necrotic tissue on the left ear and skin rashes, erythematous macula, athropic scarring, hyperpigmentation on all of his body with various size and facial haemorrhage. He also suffered from thrombocytopenia, mild elevated transaminase enzyme, hyperbilirubinemia, anti-Ro/SSA was positive. Intravenous fluid, methyprednisolone, intravenous immunoglobulin (IVIG), blood, and thrombocyte concentrate transfution were given. Two cases of neonatal lupus erythematous had been presented. Diagnosis based on clinical presentation and maternal auto antibody on neonate. Organ involvement in NLE can occur as single or multiple manifestations.
Abstract: The task of strategic information technology
management is to focus on adapting technology to ensure
competitiveness. A key factor for success in this sector is awareness
and readiness to deploy new technologies and exploit the services
they offer. Recently, the need for more flexible and dynamic user
interfaces (UIs) has been recognized, especially in mobile
applications. An ongoing research project (MOP), initiated by TUT
in Finland, is looking at how mobile device UIs can be adapted for
different needs and contexts. It focuses on examining the possibilities
to develop adapter software for solving the challenges related to the
UI and its flexibility in mobile devices. This approach has great
potential for enhancing information transfer in mobile devices, and
consequently for improving information management. The
technology presented here could be one of the key emerging
technologies in the information technology sector in relation to
mobile devices and telecommunications.
Abstract: The Iranian bentonite was first characterized by
Scanning Electron Microscopy (SEM), Inductively Coupled Plasma
mass spectrometry (ICP-MS), X-ray fluorescence (XRF), X-ray
Diffraction (XRD) and BET. The bentonite was then treated
thermally between 150°C-250°C at 15min, 45min and 90min and
also was activated chemically with different concentration of
sulphuric acid (3N, 5N and 10N). Although the results of thermal
activated-bentonite didn-t show any considerable changes in specific
surface area and Cation Exchange Capacity (CEC), but the results of
chemical treated bentonite demonstrated that such properties have
been improved by acid activation process.
Abstract: Natural convection heat transfer from a heated
horizontal semi-circular cylinder (flat surface upward) has been
investigated for the following ranges of conditions; Grashof number,
and Prandtl number. The governing partial differential equations
(continuity, Navier-Stokes and energy equations) have been solved
numerically using a finite volume formulation. In addition, the role of
the type of the thermal boundary condition imposed at cylinder
surface, namely, constant wall temperature (CWT) and constant heat
flux (CHF) are explored. Natural convection heat transfer from a
heated horizontal semi-circular cylinder (flat surface upward) has
been investigated for the following ranges of conditions; Grashof
number, and Prandtl number, . The governing partial differential
equations (continuity, Navier-Stokes and energy equations) have
been solved numerically using a finite volume formulation. In
addition, the role of the type of the thermal boundary condition
imposed at cylinder surface, namely, constant wall temperature
(CWT) and constant heat flux (CHF) are explored. The resulting flow
and temperature fields are visualized in terms of the streamline and
isotherm patterns in the proximity of the cylinder. The flow remains
attached to the cylinder surface over the range of conditions spanned
here except that for and ; at these conditions, a separated flow
region is observed when the condition of the constant wall
temperature is prescribed on the surface of the cylinder. The heat
transfer characteristics are analyzed in terms of the local and average
Nusselt numbers. The maximum value of the local Nusselt number
always occurs at the corner points whereas it is found to be minimum
at the rear stagnation point on the flat surface. Overall, the average
Nusselt number increases with Grashof number and/ or Prandtl
number in accordance with the scaling considerations. The numerical
results are used to develop simple correlations as functions of
Grashof and Prandtl number thereby enabling the interpolation of the
present numerical results for the intermediate values of the Prandtl or
Grashof numbers for both thermal boundary conditions.
Abstract: This paper describes the development, modeling, and
testing of skyhook and MiniMax control strategies of semi-active
suspension. The control performances are investigated using
Matlab/Simulink [1], with a two-degree-of-freedom quarter car semiactive
suspension system model. The comparison and evaluation of
control result are made using software-in-the-loop simulation (SILS)
method. This paper also outlines the development of a hardware-inthe-
loop simulation (HILS) system. The simulation results show that
skyhook strategy can significantly reduce the resonant peak of body
and provide improvement in vehicle ride comfort. Otherwise,
MiniMax strategy can be employed to effectively improve drive
safety of vehicle by influencing wheel load. The two strategies can
be switched to control semi-active suspension system to fulfill
different requirement of vehicle in different stages.
Abstract: The aim of this research is to determine how preservice Turkish teachers perceive themselves in terms of problem solving skills. Students attending Department of Turkish Language Teaching of Gazi University Education Faculty in 2005-2006 academic year constitute the study group (n= 270) of this research in which survey model was utilized. Data were obtained by Problem Solving Inventory developed by Heppner & Peterson and Personal Information Form. Within the settings of this research, Cronbach Alpha reliability coefficient of the scale was found as .87. Besides, reliability coefficient obtained by split-half technique which splits odd and even numbered items of the scale was found as r=.81 (Split- Half Reliability). The findings of the research revealed that preservice Turkish teachers were sufficiently qualified on the subject of problem solving skills and statistical significance was found in favor of male candidates in terms of “gender" variable. According to the “grade" variable, statistical significance was found in favor of 4th graders.
Abstract: The morphology, mineralogical and chemical
composition of a low-grade nickel ore from Mpumalanga, South
Africa, were studied by scanning electron microscope (SEM), X-ray
diffraction (XRD) and X-ray fluorescence (XRF), respectively. The
ore was subjected to atmospheric agitation leaching using sulphuric
acid to investigate the effects of acid concentration, leaching
temperature, leaching time and particle size on extraction of nickel
and cobalt. Analyses results indicated the ore to be a saprolitic nickel
laterite belonging to the serpentine group of minerals. Sulphuric acid
was found to be able to extract nickel from the ore. Increased acid
concentration and temperature only produced low amounts of nickel
but improved cobalt extraction. As high as 77.44% Ni was achieved
when leaching a -106+75μm fraction with 4.0M acid concentration at
25oC. The kinetics of nickel leaching from the saprolitic ore were
studied and the activation energy was determined to be 18.16kJ/mol.
This indicated that nickel leaching reaction was diffusion controlled.
Abstract: In this paper, we apply a semismooth active set method to image inpainting. The method exploits primal and dual features of a proposed regularized total variation model, following after the technique presented in [4]. Numerical results show that the method is fast and efficient in inpainting sufficiently thin domains.
Abstract: In this work, we consider a deterministic model for
the transmission of leptospirosis which is currently spreading in the
Thai population. The SIR model which incorporates the features of
this disease is applied to the epidemiological data in Thailand. It is
seen that the numerical solutions of the SIR equations are in good
agreement with real empirical data. Further improvements are
discussed.
Abstract: Semisolid metal processing uses solid–liquid slurries
containing fine and globular solid particles uniformly distributed in a
liquid matrix, which can be handled as a solid and flow like a liquid.
In the recent years, many methods have been introduced for the
production of semisolid slurries since it is scientifically sound and
industrially viable with such preferred microstructures called
thixotropic microstructures as feedstock materials. One such process
that needs very low equipment investment and running costs is the
cooling slope. In this research by using a mechanical stirrer slurry
maker constructed by the authors, the effects of mechanical stirring
parameters such as: stirring time, stirring temperature and stirring
Speed on micro-structure and mechanical properties of A360
aluminum alloy in semi-solid forming, are investigated. It is
determined that mold temperature and holding time of part in
temperature of 580ºC have a great effect on micro-structure and
mechanical properties(stirring temperature of 585ºC, stirring time of
20 minutes and stirring speed of 425 RPM). By optimizing the
forming parameters, dendrite microstructure changes to globular and
mechanical properties improves. This is because of breaking and
globularzing dendrites of primary α-AL.
Abstract: Modeling and simulation of biochemical reactions is of great interest in the context of system biology. The central dogma of this re-emerging area states that it is system dynamics and organizing principles of complex biological phenomena that give rise to functioning and function of cells. Cell functions, such as growth, division, differentiation and apoptosis are temporal processes, that can be understood if they are treated as dynamic systems. System biology focuses on an understanding of functional activity from a system-wide perspective and, consequently, it is defined by two hey questions: (i) how do the components within a cell interact, so as to bring about its structure and functioning? (ii) How do cells interact, so as to develop and maintain higher levels of organization and functions? In recent years, wet-lab biologists embraced mathematical modeling and simulation as two essential means toward answering the above questions. The credo of dynamics system theory is that the behavior of a biological system is given by the temporal evolution of its state. Our understanding of the time behavior of a biological system can be measured by the extent to which a simulation mimics the real behavior of that system. Deviations of a simulation indicate either limitations or errors in our knowledge. The aim of this paper is to summarize and review the main conceptual frameworks in which models of biochemical networks can be developed. In particular, we review the stochastic molecular modelling approaches, by reporting the principal conceptualizations suggested by A. A. Markov, P. Langevin, A. Fokker, M. Planck, D. T. Gillespie, N. G. van Kampfen, and recently by D. Wilkinson, O. Wolkenhauer, P. S. Jöberg and by the author.