Abstract: A new approach to predict the 3D structures of proteins by combining the knowledge-based method and Molecular Dynamics Simulation is presented on the chicken villin headpiece subdomain (HP-36). Comparative modeling is employed as the knowledge-based method to predict the core region (Ala9-Asn28) of the protein while the remaining residues are built as extended regions (Met1-Lys8; Leu29-Phe36) which then further refined using Molecular Dynamics Simulation for 120 ns. Since the core region is built based on a high sequence identity to the template (65%) resulting in RMSD of 1.39 Å from the native, it is believed that this well-developed core region can act as a 'nucleation center' for subsequent rapid downhill folding. Results also demonstrate that the formation of the non-native contact which tends to hamper folding rate can be avoided. The best 3D model that exhibits most of the native characteristics is identified using clustering method which then further ranked based on the conformational free energies. It is found that the backbone RMSD of the best model compared to the NMR-MDavg is 1.01 Å and 3.53 Å, for the core region and the complete protein, respectively. In addition to this, the conformational free energy of the best model is lower by 5.85 kcal/mol as compared to the NMR-MDavg. This structure prediction protocol is shown to be effective in predicting the 3D structure of small globular protein with a considerable accuracy in much shorter time compared to the conventional Molecular Dynamics simulation alone.
Abstract: Increased energy demand and the concern about
environment friendly technology, renewable bio-fuels are better
alternative to petroleum products. In the present study linseed oil was
used as alternative source for diesel engine fuel and the results were
compared with baseline data of neat diesel. Performance parameters
such as brake thermal efficiency (BTE) and brake specific fuel
consumption (BSFC) and emissions parameters such as CO,
unburned hydro carbon (UBHC), NOx, CO2 and exhaust temperature
were compared. BTE of the engine was lower and BSFC was higher
when the engine was fueled with Linseed oil compared to diesel fuel.
Emission characteristics are better than diesel fuel. NOx formation by
using linseed oil during the experiment was lower than diesel fuel.
Linseed oil is non edible oil, so it can be used as an extender of diesel
fuel energy source for small and medium energy needs.
Abstract: In this paper, a new automated methodology to detect the optic disc (OD) automatically in retinal images from patients with risk of being affected by Diabetic Retinopathy (DR) and Macular Edema (ME) is presented. The detection procedure comprises two independent methodologies. On one hand, a location methodology obtains a pixel that belongs to the OD using image contrast analysis and structure filtering techniques and, on the other hand, a boundary segmentation methodology estimates a circular approximation of the OD boundary by applying mathematical morphology, edge detection techniques and the Circular Hough Transform. The methodologies were tested on a set of 1200 images composed of 229 retinographies from patients affected by DR with risk of ME, 431 with DR and no risk of ME and 540 images of healthy retinas. The location methodology obtained 98.83% success rate, whereas the OD boundary segmentation methodology obtained good circular OD boundary approximation in 94.58% of cases. The average computational time measured over the total set was 1.67 seconds for OD location and 5.78 seconds for OD boundary segmentation.
Abstract: This paper considers the design of a motion planner
that will simultaneously accomplish control and motion planning of a
n-link nonholonomic mobile manipulator, wherein, a n-link
holonomic manipulator is coupled with a nonholonomic mobile
platform, within an obstacle-ridden environment. This planner,
derived from the Lyapunov-based control scheme, generates
collision-free trajectories from an initial configuration to a final
configuration in a constrained environment cluttered with stationary
solid objects of different shapes and sizes. We demonstrate the
efficiency of the control scheme and the resulting acceleration
controllers of the mobile manipulator with results through computer
simulations of an interesting scenario.
Abstract: The main objectives of this study were to identify
attributes that influence customer satisfaction and determine their
relationships with customer satisfaction. The variables included in
this research are place/ambience, food quality and service quality as
independent variables and customer satisfaction as the dependent
variable. A survey questionnaire which consisted of three parts to
measure demographic factors, independent variables, and dependent
variables was constructed based on items determined by past
research. 149 respondents from one of the well known hotel in Kuala
Lumpur, MALAYSIA were selected as a sample. Psychometric
testing was conducted to determine the reliability and validity of the
questionnaire. From the findings, there were positive significant
relationship between place/ambience (r=0.563**, p=0.000) and
service quality (r=0.544**, p=0.000) with customer satisfaction.
However, although relationship between food quality and customer
satisfaction was significant, it was in the negative direction (r=-
0.268**, p=0.001). New findings were discovered after conducting
this research and previous research findings were strengthened by the
results of this research. Future researchers could concentrate on
determining attributes that influence customer satisfaction when
cost/price is not a factor and reasons for place/ambience is currently
becoming the leading factor in determining customer satisfaction.
Abstract: Economic models are complex dynamic systems with a lot of uncertainties and fuzzy data. Conventional modeling approaches using well known methods and techniques cannot provide realistic and satisfactory answers to today-s challenging economic problems. Qualitative modeling using fuzzy logic and intelligent system theories can be used to model macroeconomic models. Fuzzy Cognitive maps (FCM) is a new method been used to model the dynamic behavior of complex systems. For the first time FCMs and the Mamdani Model of Intelligent control is used to model macroeconomic models. This new model is referred as the Mamdani Rule-Based Fuzzy Cognitive Map (MBFCM) and provides the academic and research community with a new promising integrated advanced computational model. A new economic model is developed for a qualitative approach to Macroeconomic modeling. Fuzzy Controllers for such models are designed. Simulation results for an economic scenario are provided and extensively discussed
Abstract: Islamic institutions in Malaysia play a variety of
socioeconomic roles such as poverty alleviation. To perform this role,
these institutions face a major task in identifying the poverty group.
Most of these institutions measure and operationalize poverty from
the monetary perspective using variables such as income, expenditure
or consumption. In practice, most Islamic institutions in Malaysia use
the monetary approach in measuring poverty through the
conventional Poverty Line Income (PLI) method and recently, the
had al kifayah (HAK) method using total necessities of a household
from an Islamic perspective. The objective of this paper is to present
the PLI and also the HAK method. This micro-data study would
highlight the similarities and differences of both the methods.A
survey aided by a structured questionnaire was carried out on 260
selected head of households in the state of Selangor. The paper
highlights several demographic factors that are associated with the
three monetary indicators in the study, namely income, PLI and
HAK. In addition, the study found that these monetary variables are
significantly related with each other.
Abstract: Urban planning, in particular on protected landscape
areas, demands an increasing role of public participation within the
frame of the efficiency of sustainable planning process. The
development of urban planning actions in Protected Landscape areas,
as Sintra-Cascais Natural Park, should perform a methodological
process that is structured over distinct sequential stages, providing
the development of a continuous, interactive, integrated and
participative planning. From the start of Malveira da Serra and Janes
Plan process, several public participation actions were promoted, in
order to involve the local agents, stakeholders and the population in
the decision of specific local key issues and define the appropriate
priorities within the goals and strategies previously settled. As a
result, public participation encouraged an innovative process that
guarantees the efficiency of sustainable urban planning and promotes
a sustainable new way of living in community.
Abstract: The persistent nature of perfluorochemicals (PFCs) has attracted global concern in recent years. Perfluorooctanesulfonate (PFOS) and perfluorooctanoate (PFOA) are the most commonly found PFC compounds, and thus their fate and transport play key roles in PFC distribution in the natural environment. The kinetic behavior of PFOS or PFOA on boehmite consists of a fast adsorption process followed by a slow adsorption process which may be attributed to the slow transport of PFOS or PFOA into the boehmite pore surface. The adsorption isotherms estimated the maximum adsorption capacities of PFOS and PFOA on boehmite as 0.877 μg/m2 and 0.633 μg/m2, with the difference primarily due to their different functional groups. The increase of solution pH led to a moderate decrease of PFOS and PFOA adsorption, owing to the increase of ligand exchange reactions and the decrease of electrostatic interactions. The presence of NaCl in solution demonstrated negative effects for PFOS and PFOA adsorption on boehmite surfaces, with potential mechanisms being electrical double layer compression, competitive adsorption of chloride.
Abstract: In this paper we present a substantiation of a new
Laguerre-s type iterative method for solving of a nonlinear
polynomial equations systems with real coefficients. The problems of
its implementation, including relating to the structural choice of
initial approximations, were considered. Test examples demonstrate
the effectiveness of the method at the solving of many practical
problems solving.
Abstract: Metrics is the process by which numbers or symbols
are assigned to attributes of entities in the real world in such a way as
to describe them according to clearly defined rules. Software metrics
are instruments or ways to measuring all the aspect of software
product. These metrics are used throughout a software project to
assist in estimation, quality control, productivity assessment, and
project control. Object oriented software metrics focus on
measurements that are applied to the class and other characteristics.
These measurements convey the software engineer to the behavior of
the software and how changes can be made that will reduce
complexity and improve the continuing capability of the software.
Object oriented software metric can be classified in two types static
and dynamic. Static metrics are concerned with all the aspects of
measuring by static analysis of software and dynamic metrics are
concerned with all the measuring aspect of the software at run time.
Major work done before, was focusing on static metric. Also some
work has been done in the field of dynamic nature of the software
measurements. But research in this area is demanding for more work.
In this paper we give a set of dynamic metrics specifically for
polymorphism in object oriented system.
Abstract: In wireless and mobile communications, this progress
provides opportunities for introducing new standards and improving
existing services. Supporting multimedia traffic with wireless networks
quality of service (QoS). In this paper, a grey-fuzzy controller for radio
resource management (GF-RRM) is presented to maximize the number
of the served calls and QoS provision in wireless networks. In a
wireless network, the call arrival rate, the call duration and the
communication overhead between the base stations and the control
center are vague and uncertain. In this paper, we develop a method to
predict the cell load and to solve the RRM problem based on the
GF-RRM, and support the present facility has been built on the
application-level of the wireless networks. The GF-RRM exhibits the
better adaptability, fault-tolerant capability and performance than other
algorithms. Through simulations, we evaluate the blocking rate, update
overhead, and channel acquisition delay time of the proposed method.
The results demonstrate our algorithm has the lower blocking rate, less
updated overhead, and shorter channel acquisition delay.
Abstract: The fast growth in complexity coupled with requests for shorter development periods for embedded systems are bringing demands towards a more effective, i.e. higher-abstract, design process for hardaware/software integrated design. In Software Engineering area, Model Driven Architecture (MDA) and Executable UML (xUML) has been accepted to bring further improvement in software design. This paper constructs MDA and xUML stepwise transformations from an abstract specification model to a more concrete implementation model using the refactoring technique for hardaware/software integrated design. This approach provides clear and structured models which enables quick exploration and synthesis, and early stage verification.
Abstract: In this paper, we consider a two-neuron system with time-delayed connections between neurons. By analyzing the associated characteristic transcendental equation, its linear stability is investigated and Hopf bifurcation is demonstrated. Some explicit formulae for determining the stability and the direction of the Hopf bifurcation periodic solutions bifurcating from Hopf bifurcations are obtained by using the normal form theory and center manifold theory. Some numerical simulation results are given to support the theoretical predictions. Finally, main conclusions are given.
Abstract: At present, dictionary attack has been the basic tool for
recovering key passwords. In order to avoid dictionary attack, users
purposely choose another character strings as passwords. According to
statistics, about 14% of users choose keys on a keyboard (Kkey, for
short) as passwords. This paper develops a framework system to attack
the password chosen from Kkeys and analyzes its efficiency. Within
this system, we build up keyboard rules using the adjacent and parallel
relationship among Kkeys and then use these Kkey rules to generate
password databases by depth-first search method. According to the
experiment results, we find the key space of databases derived from
these Kkey rules that could be far smaller than the password databases
generated within brute-force attack, thus effectively narrowing down
the scope of attack research. Taking one general Kkey rule, the
combinations in all printable characters (94 types) with Kkey adjacent
and parallel relationship, as an example, the derived key space is about
240 smaller than those in brute-force attack. In addition, we
demonstrate the method's practicality and value by successfully
cracking the access password to UNIX and PC using the password
databases created
Abstract: In this paper, the shape design process is briefly discussed emphasizing the use of topology optimization in the conceptual design stage. The basic idea is to view feasible domains for sensitivity region concepts. In this method, the main process consists of two steps: as the design moves further inside the feasible domain using Taguchi method, and thus becoming more successful topology optimization, the sensitivity region becomes larger. In designing a double-eccentric butterfly valve, related to hydrodynamic performance and disc structure, are discussed where the use of topology optimization has proven to dramatically improve an existing design and significantly decrease the development time of a shape design. Computational Fluid Dynamics (CFD) analysis results demonstrate the validity of this approach.
Abstract: Based on the sources- smoothed rank profile (SRP) and modified minimum description length (MMDL) principle, a method for estimation of the source coherency structure (SCS) and the number of wideband sources is proposed in this paper. Instead of focusing, we first use a spatial smoothing technique to pre-process the array covariance matrix of each frequency for de-correlating the sources and then use smoothed rank profile to determine the SCS and the number of wideband sources. We demonstrate the availability of the method by numerical simulations.
Abstract: this paper presents an auto-regressive network called the Auto-Regressive Multi-Context Recurrent Neural Network (ARMCRN), which forecasts the daily peak load for two large power plant systems. The auto-regressive network is a combination of both recurrent and non-recurrent networks. Weather component variables are the key elements in forecasting because any change in these variables affects the demand of energy load. So the AR-MCRN is used to learn the relationship between past, previous, and future exogenous and endogenous variables. Experimental results show that using the change in weather components and the change that occurred in past load as inputs to the AR-MCRN, rather than the basic weather parameters and past load itself as inputs to the same network, produce higher accuracy of predicted load. Experimental results also show that using exogenous and endogenous variables as inputs is better than using only the exogenous variables as inputs to the network.
Abstract: This paper presents a cold flow simulation study of a small gas turbine combustor performed using laboratory scale test rig. The main objective of this investigation is to obtain physical insight of the main vortex, responsible for the efficient mixing of fuel and air. Such models are necessary for predictions and optimization of real gas turbine combustors. Air swirler can control the combustor performance by assisting in the fuel-air mixing process and by producing recirculation region which can act as flame holders and influences residence time. Thus, proper selection of a swirler is needed to enhance combustor performance and to reduce NOx emissions. Three different axial air swirlers were used based on their vane angles i.e., 30°, 45°, and 60°. Three-dimensional, viscous, turbulent, isothermal flow characteristics of the combustor model operating at room temperature were simulated via Reynolds- Averaged Navier-Stokes (RANS) code. The model geometry has been created using solid model, and the meshing has been done using GAMBIT preprocessing package. Finally, the solution and analysis were carried out in a FLUENT solver. This serves to demonstrate the capability of the code for design and analysis of real combustor. The effects of swirlers and mass flow rate were examined. Details of the complex flow structure such as vortices and recirculation zones were obtained by the simulation model. The computational model predicts a major recirculation zone in the central region immediately downstream of the fuel nozzle and a second recirculation zone in the upstream corner of the combustion chamber. It is also shown that swirler angles changes have significant effects on the combustor flowfield as well as pressure losses.
Abstract: Textile structures are engineered and fabricated to
meet worldwide structural applications. Nevertheless, research
varying textile structure on natural fibre as composite reinforcement
was found to be very limited. Most of the research is focusing on
short fibre and random discontinuous orientation of the reinforcement
structure. Realizing that natural fibre (NF) composite had been
widely developed to be used as synthetic fibre composite
replacement, this research attempted to examine the influence of
woven and cross-ply laminated structure towards its mechanical
performances. Laminated natural fibre composites were developed
using hand lay-up and vacuum bagging technique. Impact and
flexural strength were investigated as a function of fibre type (coir
and kenaf) and reinforcement structure (imbalanced plain woven,
0°/90° cross-ply and +45°/-45° cross-ply). Multi-level full factorial
design of experiment (DOE) and analysis of variance (ANOVA) was
employed to impart data as to how fibre type and reinforcement
structure parameters affect the mechanical properties of the
composites. This systematic experimentation has led to determination
of significant factors that predominant influences the impact and
flexural properties of the textile composites. It was proven that both
fibre type and reinforcement structure demonstrated significant
difference results. Overall results indicated that coir composite and
woven structure exhibited better impact and flexural strength. Yet,
cross-ply composite structure demonstrated better fracture resistance.