Abstract: The aim of this article is to narrate the utility of novel simulation approach i.e. convolution method to predict blood concentration of drug utilizing dissolution data of salbutamol sulphate microparticulate formulations with different release patterns (1:1, 1:2 and 1:3, drug:polymer). Dissolution apparatus II USP 2007 and 900 ml double distilled water stirrd at 50 rpm was employed for dissolution analysis. From dissolution data, blood drug concentration was determined, and in return predicted blood drug concentration data was used to calculate the pharmacokinetic parameters i.e. Cmax, Tmax, and AUC. Convolution is a good biwaiver technique; however its better utility needs it application in the conditions where biorelevant dissolution media are used.
Abstract: In this study, direct numerical simulation for the bubble condensation in the subcooled boiling flow was performed. The main goal was to develop the CFD modeling for the bubble condensation and to evaluate the accuracy of the VOF model with the developed CFD modeling. CFD modeling for the bubble condensation was developed by modeling the source terms in the governing equations of VOF model using UDF. In the modeling, the amount of condensation was determined using the interfacial heat transfer coefficient obtained from the bubble velocity, liquid temperature and bubble diameter every time step. To evaluate the VOF model using the CFD modeling for the bubble condensation, CFD simulation results were compared with SNU experimental results such as bubble volume and shape, interfacial area, bubble diameter and bubble velocity. Simulation results predicted well the behavior of the actual condensing bubble. Therefore, it can be concluded that the VOF model using the CFD modeling for the bubble condensation will be a useful computational fluid dynamics tool for analyzing the behavior of the condensing bubble in a wide range of the subcooled boiling flow.
Abstract: This paper introduces the application of seismic wave method in earthquake prediction and early estimation. The advantages of the seismic wave method over the traditional earthquake prediction method are demonstrated. An example is presented in this study to show the accuracy and efficiency of using the seismic wave method in predicting a medium-sized earthquake swarm occurred in Wencheng, Zhejiang, China. By applying this method, correct predictions were made on the day after this earthquake swarm started and the day the maximum earthquake occurred, which provided scientific bases for governmental decision-making.
Abstract: Nowadays predicting political risk level of country
has become a critical issue for investors who intend to achieve
accurate information concerning stability of the business
environments. Since, most of the times investors are layman and
nonprofessional IT personnel; this paper aims to propose a
framework named GECR in order to help nonexpert persons to
discover political risk stability across time based on the political
news and events.
To achieve this goal, the Bayesian Networks approach was
utilized for 186 political news of Pakistan as sample dataset.
Bayesian Networks as an artificial intelligence approach has been
employed in presented framework, since this is a powerful technique
that can be applied to model uncertain domains. The results showed
that our framework along with Bayesian Networks as decision
support tool, predicted the political risk level with a high degree of
accuracy.
Abstract: In a competitive energy market, system reliability
should be maintained at all times. Power system operation being of
online in nature, the energy balance requirements must be satisfied to
ensure reliable operation the system. To achieve this, information
regarding the expected status of the system, the scheduled
transactions and the relevant inputs necessary to make either a
transaction contract or a transmission contract operational, have to be
made available in real time. The real time procedure proposed,
facilitates this. This paper proposes a quadratic curve learning
procedure, which enables a generator-s contribution to the retailer
demand, power loss of transaction in a line at the retail end and its
associated losses for an oncoming operating scenario to be predicted.
Matlab program was used to test in on a 24-bus IEE Reliability Test
System, and the results are found to be acceptable.
Abstract: Group contribution methods such as the UNIFAC are
of major interest to researchers and engineers involved synthesis,
feasibility studies, design and optimization of separation processes as
well as other applications of industrial use. Reliable knowledge of
the phase equilibrium behavior is crucial for the prediction of the fate
of the chemical in the environment and other applications. The
objective of this study was to predict the solubility of selected
volatile organic compounds (VOCs) in glycol polymers and
biodiesel. Measurements can be expensive and time consuming,
hence the need for thermodynamic models. The results obtained in
this study for the infinite dilution activity coefficients compare very
well those published in literature obtained through measurements. It
is suggested that in preliminary design or feasibility studies of
absorption systems for the abatement of volatile organic compounds,
prediction procedures should be implemented while accurate fluid
phase equilibrium data should be obtained from experiment.
Abstract: The effects of global warming on India vary from the
submergence of low-lying islands and coastal lands to the melting of
glaciers in the Indian Himalayas, threatening the volumetric flow rate
of many of the most important rivers of India and South Asia. In
India, such effects are projected to impact millions of lives. As a
result of ongoing climate change, the climate of India has become
increasingly volatile over the past several decades; this trend is
expected to continue.
Climate change is one of the most important global environmental
challenges, with implications for food production, water supply,
health, energy, etc. Addressing climate change requires a good
scientific understanding as well as coordinated action at national and
global level. The climate change issue is part of the larger challenge
of sustainable development. As a result, climate policies can be more
effective when consistently embedded within broader strategies
designed to make national and regional development paths more
sustainable. The impact of climate variability and change, climate
policy responses, and associated socio-economic development will
affect the ability of countries to achieve sustainable development
goals.
A very well calibrated Soil and Water Assessment Tool (R2 =
0.9968, NSE = 0.91) was exercised over the Khatra sub basin of the
Kangsabati River watershed in Bankura district of West Bengal,
India, in order to evaluate projected parameters for agricultural
activities. Evapotranspiration, Transmission Losses, Potential
Evapotranspiration and Lateral Flow to reach are evaluated from the
years 2041-2050 in order to generate a picture for sustainable
development of the river basin and its inhabitants.
India has a significant stake in scientific advancement as well as
an international understanding to promote mitigation and adaptation.
This requires improved scientific understanding, capacity building,
networking and broad consultation processes. This paper is a
commitment towards the planning, management and development of
the water resources of the Kangsabati River by presenting detailed
future scenarios of the Kangsabati river basin, Khatra sub basin, over
the mentioned time period.
India-s economy and societal infrastructures are finely tuned to the
remarkable stability of the Indian monsoon, with the consequence
that vulnerability to small changes in monsoon rainfall is very high.
In 2002 the monsoon rains failed during July, causing profound loss
of agricultural production with a drop of over 3% in India-s GDP.
Neither the prolonged break in the monsoon nor the seasonal rainfall
deficit was predicted. While the general features of monsoon
variability and change are fairly well-documented, the causal
mechanisms and the role of regional ecosystems in modulating the
changes are still not clear. Current climate models are very poor at
modelling the Asian monsoon: this is a challenging and critical
region where the ocean, atmosphere, land surface and mountains all
interact. The impact of climate change on regional ecosystems is
likewise unknown. The potential for the monsoon to become more
volatile has major implications for India itself and for economies
worldwide. Knowledge of future variability of the monsoon system,
particularly in the context of global climate change, is of great
concern for regional water and food security.
The major findings of this paper were that of all the chosen
projected parameters, transmission losses, soil water content,
potential evapotranspiration, evapotranspiration and lateral flow to
reach, display an increasing trend over the time period of years 2041-
2050.
Abstract: Most neural network (NN) models of human category learning use a gradient-based learning method, which assumes that locally-optimal changes are made to model parameters on each learning trial. This method tends to under predict variability in individual-level cognitive processes. In addition many recent models of human category learning have been criticized for not being able to replicate rapid changes in categorization accuracy and attention processes observed in empirical studies. In this paper we introduce stochastic learning algorithms for NN models of human category learning and show that use of the algorithms can result in (a) rapid changes in accuracy and attention allocation, and (b) different learning trajectories and more realistic variability at the individual-level.
Abstract: Circular tubes have been widely used as structural
members in engineering application. Therefore, its collapse behavior
has been studied for many decades, focusing on its energy absorption
characteristics. In order to predict the collapse behavior of members,
one could rely on the use of finite element codes or experiments.
These tools are helpful and high accuracy but costly and require
extensive running time. Therefore, an approximating model of tubes
collapse mechanism is an alternative for early step of design. This
paper is also aimed to develop a closed-form solution of thin-walled
circular tube subjected to bending. It has extended the Elchalakani et
al.-s model (Int. J. Mech. Sci.2002; 44:1117-1143) to include the
rate of energy dissipation of rolling hinge in the circumferential
direction. The 3-D geometrical collapse mechanism was analyzed by
adding the oblique hinge lines along the longitudinal tube within the
length of plastically deforming zone. The model was based on the
principal of energy rate conservation. Therefore, the rates of internal
energy dissipation were calculated for each hinge lines which are
defined in term of velocity field. Inextensional deformation and
perfect plastic material behavior was assumed in the derivation of
deformation energy rate. The analytical result was compared with
experimental result. The experiment was conducted with a number of
tubes having various D/t ratios. Good agreement between analytical
and experiment was achieved.
Abstract: In recent years, the underground water sources in
southern Taiwan have become salinized because of saltwater
intrusions. This study explores the adsorption characteristics of
activated carbon on salinizing inorganic salts using isothermal
adsorption experiments and provides a model analysis. The
temperature range for the isothermal adsorption experiments ranged
between 5 to 45 ℃, and the amount adsorbed varied between 28.21 to
33.87 mg/g. All experimental data of adsorption can be fitted to both
the Langmuir and the Freundlich models. The thermodynamic
parameters for per chlorate onto granular activated carbon were
calculated as -0.99 to -1.11 kcal/mol for DG°, -0.6 kcal/mol for DH°,
and 1.21 to 1.84 kcal/mol for DS°. This shows that the adsorption
process of granular activated carbon is spontaneously exothermic. The
observation of adsorption behaviors under low ionic strength, low pH
values, and low temperatures is beneficial to the adsorption removal of
perchlorate with granular activated carbon.
Abstract: The present work describes a computational study of
aerodynamic characteristics of GLC305 airfoil clean and with 16.7
min ice shape (rime 212) and 22.5 min ice shape (glaze 944).The
performance of turbulence models SA, Kε, Kω Std, and Kω SST
model are observed against experimental flow fields at different
Mach numbers 0.12, 0.21, 0.28 in a range of Reynolds numbers
3x106, 6x106, and 10.5x106 on clean and iced aircraft airfoil
GLC305. Numerical predictions include lift, drag and pitching
moment coefficients at different Mach numbers and at different angle
of attacks were done. Accuracy of solutions with respect to the
effects of turbulence models, variation of Mach number, initial
conditions, grid resolution and grid spacing near the wall made the
study much sensitive. Navier Stokes equation based computational
technique is used. Results are very close to the experimental results.
It has seen that SA and SST models are more efficient than Kε and
Kω standard in under study problem.
Abstract: This paper explains the cause of nonlinearity in floor
attenuation hither to left unexplained. The performance degradation
occurring in air interface for GSM signals is quantitatively analysed
using the concept of Radiating Columns of buildings. The signal
levels were measured using Wireless Network Optimising Drive Test
Tool (E6474A of Agilent Technologies). The measurements were
taken in reflected signal environment under usual fading conditions
on actual GSM signals radiated from base stations. A mathematical
model is derived from the measurements to predict the GSM signal
levels in different floors. It was applied on three buildings and found
that the predicted signal levels deviated from the measured levels
with in +/- 2 dB for all floors. It is more accurate than the prediction
models based on Floor Attenuation Factor. It can be used for
planning proper indoor coverage in multi storey buildings.
Abstract: In pressure vessels contain hydrogen, the role of
hydrogen will be important because of hydrogen cracking problem. It
is difficult to predict what is happened in metallurgical field spite of a
lot of studies have been searched. The main role in controlling the
mass diffusion as driving force is related to stress. In this study, finite
element analysis is implemented to estimate material-s behavior
associated with hydrogen embrittlement. For this purpose, one model
of a pressure vessel is introduced that it has definite boundary and
initial conditions. In fact, finite element is employed to solve the
sequentially coupled mass diffusion with stress near a crack front in a
pressure vessel. Modeling simulation intergrarnular fracture of AISI
4135 steel due to hydrogen is investigated. So, distribution of
hydrogen and stress are obtained and they indicate that their
maximum amounts occur near the crack front. This phenomenon is
happened exactly the region between elastic and plastic field.
Therefore, hydrogen is highly mobile and can diffuse through crystal
lattice so that this zone is potential to trap high volume of hydrogen.
Consequently, crack growth and fast fracture will be happened.
Abstract: The machining of Carbon Fiber Reinforced Plastics
has come to constitute a significant challenge for many fields of
industry. The resulting surface finish of machined parts is of primary
concern for several reasons, including contact quality and impact on
the assembly. Therefore, the characterization and prediction of
roughness based on machining parameters are crucial for costeffective
operations. In this study, a PCD tool comprised of two
straight flutes was used to trim 32-ply carbon fiber laminates in a bid
to analyze the effects of the feed rate and the cutting speed on the
surface roughness. The results show that while the speed has but a
slight impact on the surface finish, the feed rate for its part affects it
strongly. A detailed study was also conducted on the effect of fiber
orientation on surface roughness, for quasi-isotropic laminates used
in aerospace. The resulting roughness profiles for the four-ply
orientation lay-up were compared, and it was found that fiber angle is
a critical parameter relating to surface roughness. One of the four
orientations studied led to very poor surface finishes, and
characteristic roughness profiles were identified and found to only
relate to the ply orientations of multilayer carbon fiber laminates.
Abstract: The paper presents a comparative performance of the
models developed to predict 28 days compressive strengths using
neural network techniques for data taken from literature (ANN-I) and
data developed experimentally for SCC containing bottom ash as
partial replacement of fine aggregates (ANN-II). The data used in the
models are arranged in the format of six and eight input parameters
that cover the contents of cement, sand, coarse aggregate, fly ash as
partial replacement of cement, bottom ash as partial replacement of
sand, water and water/powder ratio, superplasticizer dosage and an
output parameter that is 28-days compressive strength and
compressive strengths at 7 days, 28 days, 90 days and 365 days,
respectively for ANN-I and ANN-II. The importance of different
input parameters is also given for predicting the strengths at various
ages using neural network. The model developed from literature data
could be easily extended to the experimental data, with bottom ash as
partial replacement of sand with some modifications.
Abstract: A handful of propagation textbooks that discuss radio frequency (RF) propagation models merely list out the models and perhaps discuss them rather briefly; this may well be frustrating for the potential first time modeller who's got no idea on how these models could have been derived. This paper fundamentally provides an overture in modelling the radio channel. Explicitly, for the modelling practice discussed here, signal strength field measurements had to be conducted beforehand (this was done at 469 MHz); to be precise, this paper primarily concerns empirically/statistically modelling the radio channel, and thus provides results obtained from empirically modelling the environments in question. This paper, on the whole, proposes three propagation models, corresponding to three experimented environments. Perceptibly, the models have been derived by way of making the most use of statistical measures. Generally speaking, the first two models were derived via simple linear regression analysis, whereas the third have been originated using multiple regression analysis (with five various predictors). Additionally, as implied by the title of this paper, both indoor and outdoor environments have been experimented; however, (somewhat) two of the environments are neither entirely indoor nor entirely outdoor. The other environment, however, is completely indoor.
Abstract: In this paper we present an extension to Vision Based
LRTA* (VLRTA*) known as Vision Based Moving Target Search
(VMTS) for capturing unknown moving target in unknown territory
with randomly generated obstacles. Target position is unknown to the
agents and they cannot predict its position using any probability
method. Agents have omni directional vision but can see in one
direction at some point in time. Agent-s vision will be blocked by the
obstacles in the search space so agent can not see through the
obstacles. Proposed algorithm is evaluated on large number of
scenarios. Scenarios include grids of sizes from 10x10 to 100x100.
Grids had obstacles randomly placed, occupying 0% to 50%, in
increments of 10%, of the search space. Experiments used 2 to 9
agents for each randomly generated maze with same obstacle ratio.
Observed results suggests that VMTS is effective in locate target
time, solution quality and virtual target. In addition, VMTS becomes
more efficient if the number of agents is increased with proportion to
obstacle ratio.
Abstract: Sensors possess several properties of physical
measures. Whether devices that convert a sensed signal into an
electrical signal, chemical sensors and biosensors, thus all these
sensors can be considered as an interface between the physical and
electrical equipment. The problem is the analysis of the multitudes of
saved settings as input variables. However, they do not all have the
same level of influence on the outputs. In order to identify the most
sensitive parameters, those that can guide users in gathering
information on the ground and in the process of model calibration
and sensitivity analysis for the effect of each change made.
Mathematical models used for processing become very complex.
In this paper a fuzzy rule-based system is proposed as a solution
for this problem. The system collects the available signals
information from sensors. Moreover, the system allows the study of
the influence of the various factors that take part in the decision
system. Since its inception fuzzy set theory has been regarded as a
formalism suitable to deal with the imprecision intrinsic to many
problems. At the same time, fuzzy sets allow to use symbolic models.
In this study an example was applied for resolving variety of
physiological parameters that define human health state. The
application system was done for medical diagnosis help. The inputs
are the signals expressed the cardiovascular system parameters, blood
pressure, Respiratory system paramsystem was done, it will be able
to predict the state of patient according any input values.
Abstract: The choice of finite element to use in order to predict
nonlinear static or dynamic response of complex structures becomes
an important factor. Then, the main goal of this research work is to
focus a study on the effect of the in-plane rotational degrees of
freedom in linear and geometrically non linear static and dynamic
analysis of thin shell structures by flat shell finite elements. In this
purpose: First, simple triangular and quadrilateral flat shell finite
elements are implemented in an incremental formulation based on the
updated lagrangian corotational description for geometrically
nonlinear analysis. The triangular element is a combination of DKT
and CST elements, while the quadrilateral is a combination of DKQ
and the bilinear quadrilateral membrane element. In both elements,
the sixth degree of freedom is handled via introducing fictitious
stiffness. Secondly, in the same code, the sixth degrees of freedom in
these elements is handled differently where the in-plane rotational
d.o.f is considered as an effective d.o.f in the in-plane filed
interpolation. Our goal is to compare resulting shell elements. Third,
the analysis is enlarged to dynamic linear analysis by direct
integration using Newmark-s implicit method. Finally, the linear
dynamic analysis is extended to geometrically nonlinear dynamic
analysis where Newmark-s method is used to integrate equations of
motion and the Newton-Raphson method is employed for iterating
within each time step increment until equilibrium is achieved. The
obtained results demonstrate the effectiveness and robustness of the
interpolation of the in-plane rotational d.o.f. and present deficiencies
of using fictitious stiffness in dynamic linear and nonlinear analysis.
Abstract: In this paper we used data mining techniques to
identify outlier patients who are using large amount of drugs over a
long period of time. Any healthcare or health insurance system
should deal with the quantities of drugs utilized by chronic diseases
patients. In Kingdom of Bahrain, about 20% of health budget is spent
on medications. For the managers of healthcare systems, there is no
enough information about the ways of drug utilization by chronic
diseases patients, is there any misuse or is there outliers patients. In
this work, which has been done in cooperation with information
department in the Bahrain Defence Force hospital; we select the data
for Cardiac patients in the period starting from 1/1/2008 to
December 31/12/2008 to be the data for the model in this paper. We
used three techniques for finding the drug utilization for cardiac
patients. First we applied a clustering technique, followed by
measuring of clustering validity, and finally we applied a decision
tree as classification algorithm. The clustering results is divided into
three clusters according to the drug utilization, for 1603 patients, who
received 15,806 prescriptions during this period can be partitioned
into three groups, where 23 patients (2.59%) who received 1316
prescriptions (8.32%) are classified to be outliers. The classification
algorithm shows that the use of average drug utilization and the age,
and the gender of the patient can be considered to be the main
predictive factors in the induced model.