Abstract: Radiolabeled cyclic RGD peptides targeting integrin αvβ3 are reported as promising agents for the early diagnosis of metastatic tumors. With an aim to improve tumor uptake and retention of the peptide, cyclic RGD peptide dimer E[c (RGDfK)] 2 (E = Glutamic acid, f = phenyl alanine, K = lysine) coupled to the bifunctional chelator DOTA was custom synthesized and radiolabelled with 68Ga. Radiolabelling of cyclic RGD peptide dimer with 68Ga was carried out using HEPES buffer and biological evaluation of the complex was done in nude mice bearing HT29 tumors.
Abstract: Seasonal variability of nutrients concentration in the Baltic Sea using the 3D ecosystem numerical model 3D-CEMBS has been investigated. Additionally this study shows horizontal and vertical distribution of nutrients in the Baltic Sea. Model domain is an extended Baltic Sea area divided into 600x640 horizontal grid cells. Aside from standard hydrodynamic parameters 3D-CEMBS produces modeled ecological variables such as: three types of phytoplankton, two detrital classes, dissolved oxygen and the nutrients (nitrate, ammonium, phosphate and silicate). The presented model allows prediction of parameters that describe distribution of nutrients concentration and phytoplankton biomass. 3D-CEMBS can be used to study the effect of different hydrodynamic and biogeochemical processes on distributions of these variables in a larger scale.
Abstract: This study uses natural water and the surface properties of powdered activated carbon to acclimatize organics, forming biofilms on the surface of powdered activated carbon. To investigate the influence of different hydraulic retention times on the removal efficacy of trace organics in raw water, and to determine the optimal hydraulic retention time of a biological powdered activated carbon system, this study selects ozone-treated water processed by Feng-shan Advanced Water Purification Plant in southern Taiwan for the experiment. The evaluation indicators include assimilable organic carbon, dissolved organic carbon, and total organic carbon. The results of this study can improve the quality of drinking water treated using advanced water purification procedures.
Abstract: The main purpose of the research is to address the role of psychological harassment behaviors (mobbing) to which employees are exposed and personality characteristics over work alienation. Research population was composed of the employees of Provincial Special Administration. A survey with four sections was created to measure variables and reach out the basic goals of the research. Correlation and step-wise regression analyses were performed to investigate the separate and overall effects of sub-dimensions of psychological harassment behaviors and personality characteristic on work alienation of employees. Correlation analysis revealed significant but weak relationships between work alienation and psychological harassment and personality characteristics. Step-wise regression analysis revealed also significant relationships between work alienation variable and assault to personality, direct negative behaviors (sub dimensions of mobbing) and openness (sub-dimension of personality characteristics). Each variable was introduced into the model step by step to investigate the effects of significant variables in explaining the variations in work alienation. While the explanation ratio of the first model was 13%, the last model including three variables had an explanation ratio of 24%.
Abstract: Environmental investments, including ecological
projects, relating to the protection of atmosphere are today a need.
However, investing in the environment should be based on rational
management rules. This comes across a problem of selecting a
method to assess substances reduced during projects. Therefore, a
method allowing for the assessment of decision rationality has to be
found.
The purpose of this article is to present and systematise pollution
reduction assessment methods and illustrate theoretical analyses with
empirical data.
Empirical results confirm theoretical considerations, which proved
that the only method for judging pollution reduction, free of apparent
disadvantages, is the Eco 99-ratio method. To make decisions on
environmental projects, financing institutions should take into
account a rationality rule. Therefore the Eco 99-ratio method could
be applied to make decisions relating to environmental investments in
the area of air protection.
Abstract: Location-aware computing is a type of pervasive
computing that utilizes user-s location as a dominant factor for
providing urban services and application-related usages. One of the
important urban services is navigation instruction for wayfinders in a
city especially when the user is a tourist. The services which are
presented to the tourists should provide adapted location aware
instructions. In order to achieve this goal, the main challenge is to
find spatial relevant objects and location-dependent information. The
aim of this paper is the development of a reusable location-aware
model to handle spatial relevancy parameters in urban location-aware
systems. In this way we utilized ontology as an approach which could
manage spatial relevancy by defining a generic model. Our
contribution is the introduction of an ontological model based on the
directed interval algebra principles. Indeed, it is assumed that the
basic elements of our ontology are the spatial intervals for the user
and his/her related contexts. The relationships between them would
model the spatial relevancy parameters. The implementation language
for the model is OWLs, a web ontology language. The achieved
results show that our proposed location-aware model and the
application adaptation strategies provide appropriate services for the
user.
Abstract: The antimicrobial, antiplasmid and cytotoxic activities of marine algae Halimeda opuntia and Sarconema filiforme were investigated. Antimicrobial bioassay against some human pathogenic bacteria and yeast were conducted using disc diffusion method. Halimeda extract exhibited antibacterial activity against six species of microrganisms, with significant inhibition against Staphylococcus aureus. While Sarconema extract was better potent as antifungal against Candida albicans. Comparative antibacterial studies showed that Halimeda extract showed equivalent or better activity as compared with commercial antibiotic when tested against Staphylococcus aureus. Further tests conducted using dilution method showed both extracts as having bacteriostatic mode of action against the tested microorganisms. Methanol extract of two species showed significant cytotoxicity (LC50
Abstract: Dredging activities inevitably cause sediment
dispersion. In certain locations, where there are important ecological
areas such as mangroves or coral reefs, carefully planning the
dredging can significantly reduce negative impacts. This article
utilizes the dredging at Phuket port, Thailand, as a case study to
demonstrate how computer simulations can be helpful to protect
existing coral reefs. A software package named MIKE21 was
applied. Necessary information required by the simulations was
gathered. After calibrating and verifying the model, various dredging
scenario were simulated to predict spoil movement. The simulation
results were used as guidance to setting up an environmental
measure. Finally, the recommendation to dredge during flood tide
with silt curtains installed was made.
Abstract: While service quality is acceptably most valued in the tourism industry, the issue of safety and security plays a key role in sustaining the industry success. Such an issue has been part of Thailand-s tourism development and promotion for several years. Evidently, the Tourist Police Department was set up for this purpose. Its main responsibility is to deal with international tourists- safety and confidence in travelling within Thai territory. However, to strengthen the tourism safety of the country, it is important to better understand international tourists- safety concerns about Thailand. This article seeks to compare international tourists- safety needs and Thai tourist polices- perception towards the tourists- safety concern to determine what measure should be taken to assure the tourist of Thailand-s secure environment. Through the employment of quantitative and qualitative methodological approaches, the tourism safety need of international tourists from Europe, North America and Asia was excavated, how Thai tourist polices and local polices perceived the international tourist-s safety concern was investigated, and opinion and experiences about how the police deal with international tourists- problems in eight touristic areas were also explored. A comparative result reveals a certain degrees of differences in international tourists- safety needs and Thai polices- perception towards their needs. The tourism safety prevention and protection measure and practice are also suggested.
Abstract: In this paper, a fuzzy algorithm and a fuzzy multicriteria
decision framework are developed and used for a practical
question of optimizing biofuels policy making. The methodological
framework shows how to incorporate fuzzy set theory in a decision
process of finding a sustainable biofuels policy among several policy
options. Fuzzy set theory is used here as a tool to deal with
uncertainties of decision environment, vagueness and ambiguities of
policy objectives, subjectivities of human assessments and imprecise
and incomplete information about the evaluated policy instruments.
Abstract: Although considerable amount of research has attested to the link between work-to-family conflict (WFC) and family-to-work conflict (FWC) and psychological strain and wellbeing, there is a paucity of research investigating the phenomenon in the context of social workers. Moreover, very little is known about the impact of WFC and FWC in developing countries. The present study investigated the mediating effect of psychological strain on the relationship between WFC and FWC with wellbeing of social workers in India. Our findings show that WFC and FWC are influential antecedents of wellbeing; their influence is both direct on psychological strain, and indirect on wellbeing transmitted through psychological strain. Implications of the findings are discussed.
Abstract: Well-being has been given special emphasis in quality
of life. It involves living a meaningful, life satisfaction, stability and
happiness in life. Well-being also concerns the satisfaction of
physical, psychological, social needs and demands of an individual.
The purpose of this study was to validate three-factor measurement
model of well-being using structural equation modeling (SEM). The
conceptions of well-being measured such dimensions as physical,
psychological and social well-being. This study was done based on a
total sample of 650 adolescents from east-coast of peninsular
Malaysia. The Well-Being Scales which was adapted from [1] was
used in this study. The items were hypothesized a priori to have nonzero
loadings on all dimensions in the model. The findings of the
SEM demonstrated that it is a good fitting model which the proposed
model fits the driving theory; (x2df = 1.268; GFI = .994; CFI = .998;
TLI= .996; p = .255; RMSEA = .021). Composite reliability (CR)
was .93 and average variance extracted (AVE) was 58%. The model
in this study fits with the sample of data and well-being is important
to bring sustainable development to the mainstream.
Abstract: The psychological and physical trauma associated with the loss of a human limb can severely impact on the quality of life of an amputee rendering even the most basic of tasks very difficult. A prosthetic device can be of great benefit to the amputee in the performance of everyday human tasks. This paper outlines a proposed mechanical design of a 12 degree-of-freedom SMA actuated artificial hand. It is proposed that the SMA wires be embedded intrinsically within the hand structure which will allow for significant flexibility for use either as a prosthetic hand solution, or as part of a complete lower arm prosthetic solution. A modular approach is taken in the design facilitating ease of manufacture and assembly, and more importantly, also allows the end user to easily replace SMA wires in the event of failure. A biomimetric approach has been taken during the design process meaning that the artificial hand should replicate that of a human hand as far as is possible with due regard to functional requirements. The proposed design has been exposed to appropriate loading through the use of finite element analysis (FEA) to ensure that it is structurally sound. Theoretical analysis of the mechanical framework was also carried out to establish the limits of the angular displacement and velocity of the finger tip as well finger tip force generation. A combination of various polymers and Titanium, which are suitably lightweight, are proposed for the manufacture of the design.
Abstract: The sensitivity of UAVs to the atmospheric effects are
apparent. All the same the meteorological support for the UAVs
missions is often non-adequate or partly missing.
In our paper we show a new complex meteorological support
system for different types of UAVs pilots, specialists and decision
makers, too. The mentioned system has two important parts with
different forecasts approach such as the statistical and dynamical
ones.
The statistical prediction approach is based on a large
climatological data base and the special analog method which is able
to select similar weather situations from the mentioned data base to
apply them during the forecasting procedure.
The applied dynamic approach uses the specific WRF model runs
twice a day and produces 96 hours, high resolution weather forecast
for the UAV users over the Hungary. An easy to use web-based
system can give important weather information over the Carpathian
basin in Central-Europe. The mentioned products can be reached via
internet connection.
Abstract: Sustainability and sustainable development have been
the main theme of many international conferences, such the UN Rio
de Janeiro 1992 Earth Summit This was followed by the appearance
of the global conferences at the late of the nineties and the early of
2000 to confirm the importance of the sustainable development .it
was focused on the importance of the economic development as it is
considered an effective tool in the operations of the sustainable
development. Industry plays a critical role in technological
innovations and research and development activities, which are
crucial for the economic and social development of any country.
Transportation and mobility are an important part or urban
economics and the quality of life. To analyze urban transportation
and its environmental impacts, a comprehensive approach is needed.
So this research aims to apply new approach for the development of
the urban communities that insure the continuity and facing the
deterioration. This approach aims to integrate sustainable transport
solutions with economic development and community development.
For that purpose we will concentrate on one of the most sustainable
cities in the world (Curitiba in Brazil) which provides the world with
a model in how to integrate sustainable transport considerations into
business development, road infrastructure development, and local
community development.
Abstract: This paper presents a linear stability analysis of
natural convection in a horizontal layer of a viscoelastic
nanofluid. The Oldroyd B model was utilized to describe the
rheological behavior of a viscoelastic nanofluid. The model
used for the nanofluid incorporated the effects of Brownian
motion and thermophoresis. The onset criterion for stationary
and oscillatory convection was derived analytically. The effects
of the Deborah number, retardation parameters, concentration
Rayleigh number, Prandtl number, and Lewis number on the
stability of the system were investigated. Results indicated that
there was competition among the processes of thermophoresis,
Brownian diffusion, and viscoelasticity which caused
oscillatory rather than stationary convection to occur.
Oscillatory instability is possible with both bottom- and
top-heavy nanoparticle distributions. Regimes of stationary and
oscillatory convection for various parameters were derived and
are discussed in detail.
Abstract: Huge losses in apple production are caused by pathogens that cannot be seen shortly after harvest. After-harvest thermotherapy treatments can considerably improve control of storage diseases on apples and become an alternative to chemical pesticides. In the years 2010-2012 carried out research in this area. Apples of 'Topaz' cultivar were harvested at optimal maturity time for long storage and subject to water bath treatment at 45, 50, 52, 55°C for 60, 120, 180 and 240 seconds. The control was untreated fruits. After 12 and 24 weeks and during so called simulated trade turnover the fruits were checked for their condition and the originators of diseases were determined by using the standard phytopathological methods. The most common originator of 'Topaz' apple infection during storage were the fungi of genus Gloeosporium. In this paper it was proven that for effective protection of 'Topaz' apples against diseases, thermotherapy by using water treatments at temperature range of 50-52°C is quite sufficient.
Abstract: Electronic Systems are the core of everyday lives.
They form an integral part in financial networks, mass transit,
telephone systems, power plants and personal computers. Electronic
systems are increasingly based on complex VLSI (Very Large Scale
Integration) integrated circuits. Initial electronic design automation is
concerned with the design and production of VLSI systems. The next
important step in creating a VLSI circuit is Physical Design. The
input to the physical design is a logical representation of the system
under design. The output of this step is the layout of a physical
package that optimally or near optimally realizes the logical
representation. Physical design problems are combinatorial in nature
and of large problem sizes. Darwin observed that, as variations are
introduced into a population with each new generation, the less-fit
individuals tend to extinct in the competition of basic necessities.
This survival of fittest principle leads to evolution in species. The
objective of the Genetic Algorithms (GA) is to find an optimal
solution to a problem .Since GA-s are heuristic procedures that can
function as optimizers, they are not guaranteed to find the optimum,
but are able to find acceptable solutions for a wide range of
problems. This survey paper aims at a study on Efficient Algorithms
for VLSI Physical design and observes the common traits of the
superior contributions.
Abstract: In studying the possibility of using plants as
rhizoremediators, barley and grass mixture which showed resistance
to various concentrations of oil were selected. The minimum
inhibitory effect of oil on these plants by morphological parameters
such as survival of plants, length and biomass of shoot and root
compared with the control was showed. In determining physiological
parameters, a slight decrease in the number of chlorophyll a and b in
the leaves of plants was noted. The differences in the ratio of the total
surface of the roots to the work surface with the growth of plants in
soil with oil in the study of adsorption of the root surface were
showed.
Abstract: Inconel718 has been widely used as a super alloy in aerospace application due to the high strength at elevated temperatures, satisfactory oxidation resistance and heat corrosion resistance. In this study, the Inconel718 has been fabricated using high technology of Metal Injection Molding (MIM) process due to the cost effective technique for producing small, complex and precision parts in high volume compared with conventional method through machining. Through MIM, the binder system is one of the most important criteria in order to successfully fabricate the Inconel718. Even though, the binder system is a temporary, but failure in the selection and removal of the binder system will affect on the final properties of the sintered parts. Therefore, the binder system based on palm oil derivative which is palm stearin has been formulated and developed to replace the conventional binder system. The rheological studies of the mixture between the powder and binders system have been determined properly in order to be successful during injection into injection molding machine. After molding, the binder holds the particles in place. The binder system has to be removed completely through debinding step. During debinding step, solvent debinding and thermal pyrolysis has been used to remove completely of the binder system. The debound part is then sintered to give the required physical and mechanical properties. The results show that the properties of the final sintered parts fulfill the Standard Metal Powder Industries Federation (MPIF) 35 for MIM parts.