Abstract: Persea declinata (Bl.) Kosterm is a member of the
Lauraceae family, widely distributed in Southeast Asia. It is from the
same genus with avocado (Persea americana Mill), which is widely
consumed as food and for medicinal purposes. In the present study,
we examined the anticancer properties of Persea declinata (Bl.)
Kosterm bark methanolic crude extract (PDM). PDM exhibited a
potent antiproliferative effect in MCF-7 human breast cancer cells,
with an IC50 value of 16.68 .g/mL after 48h of treatment. We
observed that PDM caused cell cycle arrest and subsequent apoptosis
in MCF-7 cells, as exhibited by increased population at G0/G1 phase,
higher lactate dehydrogenase (LDH) release, and DNA
fragmentation. Mechanistic studies showed that PDM caused
significant elevation in ROS production, leading to perturbation of
mitochondrial membrane potential, cell permeability, and activation
of caspases-3/7. On the other hand, real-time PCR and Western blot
analysis showed that PDM treatment increased the expression of the
proapoptotic molecule, Bax, but decreased the expression of
prosurvival proteins, Bcl-2 and Bcl-xL, in a dose-dependent manner.
These findings imply that PDM could inhibit proliferation in MCF-7
cells via cell cycle arrest and apoptosis induction, indicating its
potential as a therapeutic agent worthy of further development.
Abstract: The manufacturing technology of band cotton is very
delicate and depends to choice of certain parameters such as torsion
of warp yarn.
The fabric elasticity is achieved without the use of any elastic
material, chemical expansion, artificial or synthetic and it’s capable
of creating pressures useful for therapeutic treatments.
Before use, the band is subjected to treatments of specific
preparation for obtaining certain elasticity, however, during its
treatment, there are some regression parameters. The dependence of
manufacturing parameters on the quality of the chemical treatment
was confirmed.
The aim of this work is to improve the properties of the fabric
through the development of manufacturing technology appropriately.
Finally for the treatment of the strip pancake 100% cotton, a
treatment method is recommended.
Abstract: The mathematical analysis on radiation obtained and
the development of the solar photovoltaic (PV) array groundwater
pumping is needed in the rural areas of Thohoyandou for sizing and
power performance subject to the climate conditions within the area.
A simple methodology approach is developed for the directed
coupled solar, controller and submersible ground water pump system.
The system consists of a PV array, pump controller and submerged
pump, battery backup and charger controller. For this reason, the
theoretical solar radiation is obtained for optimal predictions and
system performance in order to achieve different design and
operating parameters. Here the examination of the PV schematic
module in a Direct Current (DC) application is used for obtainable
maximum solar power energy for water pumping. In this paper, a
simple efficient photovoltaic water pumping system is presented with
its theoretical studies and mathematical modeling of photovoltaics
(PV) system.
Abstract: Copper being one of the major intrinsic residual
impurities in steel possesses the tendency to induce severe
microstructural distortions if not controlled within certain limits.
Hence, this paper investigates the effect of this element on the
mechanical properties of construction steel with a view to ascertain
its safe limits for effective control. The experiment entails collection
of statistically scheduled samples of hot rolled profiles with varied
copper concentrations in the range of 0.12-0.39 wt. %. From these
samples were prepared standard test specimens subjected to tensile,
impact, hardness and microstructural analyses. Results show a rather
huge compromise in mechanical properties as the specimens
demonstrated 54.3%, 74.2% and 64.9% reduction in tensile strength,
impact energy and hardness respectively as copper content increases
from 0.12 wt. % to 0.39 wt. %. The steel’s abysmal performance is
due to the severe distortion of the microstructure occasioned by the
development of incoherent complex compounds which weaken the
pearlite reinforcing phase. It is concluded that the presence of copper
above 0.22 wt. % is deleterious to construction steel performance.
Abstract: Historical and ancestral bonds of the countries in the
Middle East have led to similarities in culture and context of their
societies. In addition, economical resources, such as the oil industry,
have generally been an integrative point in the region. Higher
education of a country is influenced by different national and
international factors and, regarding the mentioned bonds, it is inviting
to study the development of the countries of the Middle East in
higher education and draw some practical implications which can be
used in the educational policymaking of the region. This review
includes a data analysis on the population of international students in
the countries of the Middle East. As its second objective, a review
study on the successful countries, that is, those which host the highest
number of international students, and the strategies they have
developed to reach this state among the countries of the region, has
been conducted. Suggestions are made as to the strategies in higher
education systems of these countries which could prove useful and
practical in the development of internationalization of higher
education in the region, specifically with regard to the recruitment of
international students.
Abstract: Nanotechnology is the new cyber, according to several major leaders in this field. Just as cyber is entrenched across global society now, nano is poised to be major capabilities enabler of the next decades. Expert members from the National Nanotechnology Initiative (in U.S.) representing government and science disciplines say nano has great significance for the military and the general public. It is predicted that after next 15 years nanotechnology will replace information technology as the most economic technology platform. Nanotechnology has even wider applications than information technology.
Abstract: The aim of this paper is to analyze the ability to
identify and acquire knowledge from external sources at the regional
level in the Czech Republic. The results show that the most important
sources of knowledge for innovative activities are sources within the
businesses themselves, followed by customers and suppliers.
Furthermore, the analysis of relationships between the objective of
the innovative activity and the ability to identify and acquire
knowledge implies that knowledge obtained from (1) customers aims
at replacing outdated products and increasing product quality; (2)
suppliers aims at increasing capacity and flexibility of production;
and (3) competing businesses aims at growing market share and
increasing the flexibility of production and services. Regions should
therefore direct their support especially into development and
strengthening of networks within the value chain.
Abstract: This paper deals with the issue of biomass and sorted
municipal waste gasification and cogeneration using hot-air turbo-set.
It brings description of designed pilot plant with electrical output 80
kWe. The generated gas is burned in secondary combustion chamber
located beyond the gas generator. Flue gas flows through the heat
exchanger where the compressed air is heated and consequently
brought to a micro turbine. Except description, this paper brings our
basic experiences from operating of pilot plant (operating parameters,
contributions, problems during operating, etc.). The principal
advantage of the given cycle is the fact that there is no contact
between the generated gas and the turbine. So there is no need for
costly and complicated gas cleaning which is the main source of
operating problems in direct use in combustion engines because the
content of impurities in the gas causes operation problems to the units
due to clogging and tarring of working surfaces of engines and
turbines, which may lead as far as serious damage to the equipment
under operation. Another merit is the compact container package
making installation of the facility easier or making it relatively more
mobile. We imagine, this solution of cogeneration from biomass or
waste can be suitable for small industrial or communal applications,
for low output cogeneration.
Abstract: This research is aimed to develop the online-class
scheduling management system and improve as a complex problem
solution, this must take into consideration in various conditions and
factors. In addition to the number of courses, the number of students
and a timetable to study, the physical characteristics of each class
room and regulations used in the class scheduling must also be taken
into consideration. This system is developed to assist management in
the class scheduling for convenience and efficiency. It can provide
several instructors to schedule simultaneously. Both lecturers and
students can check and publish a timetable and other documents
associated with the system online immediately. It is developed in a
web-based application. PHP is used as a developing tool. The
database management system was MySQL. The tool that is used for
efficiency testing of the system is questionnaire. The system was
evaluated by using a Black-Box testing. The sample was composed
of 2 groups: 5 experts and 100 general users. The average and the
standard deviation of results from the experts were 3.50 and 0.67.
The average and the standard deviation of results from the general
users were 3.54 and 0.54. In summary, the results from the research
indicated that the satisfaction of users were in a good level.
Therefore, this system could be implemented in an actual workplace
and satisfy the users’ requirement effectively.
Abstract: A simple, accurate and precise direct spectrophotometric method has been developed for the determination of cefixime in tablets and capsules. The method is based on the reaction of cefixime with a mixture of potassium iodide and potassium iodate to form yellow coloured product in ethanol-distilled water medium at room temperature which absorbed maximally at 352 nm. The factors affecting the reaction product were carefully studied and optimized. The validation parameters based on International Conference on Harmonisation (ICH, USA) guidelines were followed. The effect of common excipients used as additives has been tested and the tolerance limit was calculated for the determination of cefixime. Beer’s law is obeyed in the concentration range of 4 – 24 ug mL-1 with apparent molar absorptivity of 1.52 × 104 L mol-1cm-1 and Sandell’s sensitivity of 0.033 ug/cm2/ 0.001 absorbance unit. The limits of detection and quantitation for the proposed method are 0.32 and 1.06 ug mL-1, respectively. The proposed method has been successfully applied for the determination of cefixime in pharmaceutical formulations. The results obtained by the proposed method were statistically compared with the reference method using t- and F- values and found no significant difference between the two methods. The proposed method can be used as an alternate method for routine quality control analysis of cefixime in pharmaceutical formulations.
Abstract: Red River Gum (Eucalyptus camaldulensis) is a tree
of the genus Eucalyptus widely distributed in Algeria and in the
world. The value of its aromatic secondary metabolites offers new
perspectives in the pharmaceutical industry. This strategy can
contribute to the sustainable development of our country. Preliminary
tests performed on the essential oil of Eucalyptus camendulensis
showed that this oil has antibacterial activity vis-à-vis the bacterial
strains (Enterococcus feacalis, Enterobacter cloaceai, Proteus
microsilis, Escherichia coli, Klebsiella pneumonia, and Pseudomonas
aeruginosa) and antifungic (Fusarium sporotrichioide and Fusarium
graminearum). The culture medium used was nutrient broth Muller
Hinton. The interaction between the bacteria and the essential oil is
expressed by a zone of inhibition with diameters of MIC indirectly
expression of. And we used the PDA medium to determine the fungal
activity. The extraction of the aromatic fraction (essentially oilhydrolat)
of the fresh aerian part of the Eucalyptus camendulensis
was performed by hydrodistillation. The average essential oil yield is
0.99%. The antimicrobial and fungal study of the essential oil and
hydrosol showed a high inhibitory effect on the growth of pathogens.
Abstract: In development of floating photovoltaic generation
system, finding a suitable place of installation is as important as
development of economically feasible and stable structure. Especially
since floating photovoltaic system has its facility floating on water
surface, it is extremely important to review the effects of weather
conditions such as wind, water flow and floating matters, various
factors (such as fogs) that can reduce generation efficiency, possibility
of connection with power system, and legal restrictions. The method of
investigating suitable area and resource for development of
tracking-type floating photovoltaic generation system was proposed in
this paper, which can be used for development of floating and ocean
photovoltaic system in the future.
Abstract: Business interpreting talents are in badly need for local
economic development, but currently there are problems of traditional
business interpreting training mode in China. In view of the good
opportunity for college business interpreters provided by international
trading center development in Qingdao China and with the aim of
being in line with market demand and enhancing business interpreters'
employment competitive advantage, this paper aims to explore how to
cultivate interdisciplinary business interpreting talents based on
market demand.
Abstract: This research paper aims to identify, analyze and rank
factors affecting labor productivity in Spain with respect to their
relative importance. Using a selected set of 35 factors, a structured
questionnaire survey was utilized as the method to collect data from
companies. Target population is comprised by a random
representative sample of practitioners related with the Spanish
construction industry. Findings reveal the top five ranked factors are
as follows: (1) shortage or late supply of materials; (2) clarity of the
drawings and project documents; (3) clear and daily task assignment;
(4) tools or equipment shortages; (5) level of skill and experience of
laborers. Additionally, this research also pretends to provide simple
and comprehensive recommendations so that they could be
implemented by construction managers for an effective management
of construction labor forces.
Abstract: The article presents the trends in Georgian wine
market development and evaluates the competitive advantages of
Georgia to enter the wine market based on its customs, traditions and
historical practices combined with modern technologies.
In order to analyze the supply of wine, dynamics of vineyard land
area and grape varieties are discussed, trends in wine production are
presented, trends in export and import are evaluated, local wine
market, its micro and macro environments are studied and analyzed
based on the interviews with experts and analysis of initial recording
materials.
For strengthening its position on the international market, the level
of competitiveness of Georgian wine is defined, which is evaluated
by “ex-ante” and “ex-post” methods, as well as by four basic and two
additional factors of the Porter’s diamond method; potential
advantages and disadvantages of Georgian wine are revealed.
Conclusions are made by identifying the factors that hinder the
development of Georgian wine market. Based on the conclusions,
relevant recommendations are developed.
Abstract: As an entity of the tourism system, local communities
were considered have better understanding of their region as well as
influenced positively or negatively by the tourism activities in the
region. This paper aimed to study role of community involvement in
the development of ecotourism at Kintamani Bali from two
perspectives of view, i.e. participation in the process of initiatives and
participation in the utilizing the economic benefits of tourism.
Thorough participation as an antecedent of social capital form, the
sustainability of ecotourism at Kintamani could be expected.
Abstract: One of the major goals of Spoken Dialog Systems
(SDS) is to understand what the user utters.
In the SDS domain, the Spoken Language Understanding (SLU)
Module classifies user utterances by means of a pre-definite
conceptual knowledge. The SLU module is able to recognize only the
meaning previously included in its knowledge base. Due the vastity
of that knowledge, the information storing is a very expensive
process.
Updating and managing the knowledge base are time-consuming
and error-prone processes because of the rapidly growing number of
entities like proper nouns and domain-specific nouns. This paper
proposes a solution to the problem of Name Entity Recognition
(NER) applied to a SDS domain. The proposed solution attempts to
automatically recognize the meaning associated with an utterance by
using the PANKOW (Pattern based Annotation through Knowledge
On the Web) method at runtime.
The method being proposed extracts information from the Web to
increase the SLU knowledge module and reduces the development
effort. In particular, the Google Search Engine is used to extract
information from the Facebook social network.
Abstract: This study aimed at designing and developing a
mechanical force gauge for the square watermelon mold for the first
time. It also tried to introduce the square watermelon characteristics
and its production limitations. The mechanical force gauge
performance and the product itself were also described. There are
three main designable gauge models: a. hydraulic gauge, b. strain
gauge, and c. mechanical gauge. The advantage of the hydraulic
model is that it instantly displays the pressure and thus the force
exerted by the melon. However, considering the inability to measure
forces at all directions, complicated development, high cost, possible
hydraulic fluid leak into the fruit chamber and the possible influence
of increased ambient temperature on the fluid pressure, the
development of this gauge was overruled. The second choice was to
calculate pressure using the direct force a strain gauge. The main
advantage of these strain gauges over spring types is their high
precision in measurements; but with regard to the lack of conformity
of strain gauge working range with water melon growth, calculations
were faced with problems. Finally the mechanical pressure gauge has
advantages, including the ability to measured forces and pressures on
the mold surface during melon growth; the ability to display the peak
forces; the ability to produce melon growth graph thanks to its
continuous force measurements; the conformity of its manufacturing
materials with the required physical conditions of melon growth; high
air conditioning capability; the ability to permit sunlight reaches the
melon rind (no yellowish skin and quality loss); fast and
straightforward calibration; no damages to the product during
assembling and disassembling; visual check capability of the product
within the mold; applicable to all growth environments (field,
greenhouses, etc.); simple process; low costs and so forth.
Abstract: With the rapid progress of modern cities, the railway
construction must be developing quickly in China.As a typical
high-density country, shopping center on the subway should be one
important factor during the process of urban development. The paper
discusses the influence of the layout of shopping center on the subway,
and put it in the time and space’s axis of Shanghai urban development.
We usethe digital technology to establish the database of relevant
information. And then get the change role about shopping center on
subway in Shanghaiby the Kernel density estimate.The result shows
the development of shopping center on subway has a relationship with
local economic strength, population size, policysupport, and city
construction. And the suburbanization trend of shopping center would
be increasingly significant.By this case research, we could see the
Kernel density estimate is an efficient analysis method on the spatial
layout. It could reveal the characters of layout form of shopping center
on subway in essence. And it can also be applied to the other research
of space form.
Abstract: The purposes of this research were to study concepts
and strategies of human resource development in the automotive
manufacturers and to articulate the proposals against the government
about the human resource development for automotive industry. In
the present study, qualitative study was an in-depth interview in
which the qualitative data were collected from the executive or the
executive of human resource division from five automotive
companies - Toyota Motor (Thailand) Co., Ltd., Nissan Motor
(Thailand) Co., Ltd., Mitsubishi Motors (Thailand) Co., Ltd., Honda
Automobile (Thailand) Co., Ltd., and Suzuki Motor (Thailand) Co.,
Ltd. Qualitative data analysis was performed by using inter-coder
agreement technique. The research findings were as follows:
The external factors included the current conditions of the
automotive industry, government’s policy related to the automotive
industry, technology, labor market and human resource development
systems of the country. The internal factors included management,
productive management, organizational strategies, leadership,
organizational culture and philosophy of human resource
development. These factors were affected to the different concept of
human resources development -the traditional human resource
development and the strategies of human resource development. The
organization focuses on human resources as intellectual capital and
uses the strategies of human resource development in all
development processes. The strategies of human resource
development will enhance the ability of human resources in the
organization and the country.