Abstract: This study determines the effect of naked and heparinbased
super-paramagnetic iron oxide nanoparticles on the human
cancer cell lines of A2780. Doxorubicin was used as the anticancer
drug, entrapped in the SPIO-NPs. This study aimed to decorate
nanoparticles with heparin, a molecular ligand for 'active' targeting
of cancerous cells and the application of modified-nanoparticles in
cancer treatment. The nanoparticles containing the anticancer drug
DOX were prepared by a solvent evaporation and emulsification
cross-linking method. The physicochemical properties of the
nanoparticles were characterized by various techniques, and uniform
nanoparticles with an average particle size of 110±15 nm with high
encapsulation efficiencies (EE) were obtained. Additionally, a
sustained release of DOX from the SPIO-NPs was successful.
Cytotoxicity tests showed that the SPIO-DOX-HP had higher cell
toxicity than the individual HP and confocal microscopy analysis
confirmed excellent cellular uptake efficiency. These results indicate
that HP based SPIO-NPs have potential uses as anticancer drug
carriers and also have an enhanced anticancer effect.
Abstract: Rice husk is one of the alternative fuels for Thailand because of its high potential and environmental benefits. Nonetheless, the environmental profile of the electricity production from rice husk must be assessed to ensure reduced environmental damage. A 10 MW pilot plant using rice husk as feedstock is the study site. The environmental impacts from rice husk power plant are evaluated by using the Life Cycle Assessment (LCA) methodology. Energy, material and carbon balances have been determined for tracing the system flow. Carbon closure has been used for describing of the net amount of CO2 released from the system in relation to the amount being recycled between the power plant and the CO2 adsorbed by rice husk. The transportation of rice husk to the power plant has significant on global warming, but not on acidification and photo-oxidant formation. The results showed that the impact potentials from rice husk power plant are lesser than the conventional plants for most of the categories considered; except the photo-oxidant formation potential from CO. The high CO from rice husk power plant may be due to low boiler efficiency and high moisture content in rice husk. The performance of the study site can be enhanced by improving the combustion efficiency.
Abstract: The term hybrid composite refers to the composite
containing more than one type of fiber material as reinforcing fillers.
It has become attractive structural material due to the ability of
providing better combination of properties with respect to single fiber
containing composite. The eco-friendly nature as well as processing
advantage, light weight and low cost have enhanced the attraction
and interest of natural fiber reinforced composite. The objective of
present research is to study the mechanical properties of jute-coir
fiber reinforced hybrid polypropylene (PP) composite according to
filler loading variation. In the present work composites were
manufactured by using hot press machine at four levels of fiber
loading (5, 10, 15 and 20 wt %). Jute and coir fibers were utilized at a
ratio of (1:1) during composite manufacturing. Tensile, flexural,
impact and hardness tests were conducted for mechanical
characterization. Tensile test of composite showed a decreasing trend
of tensile strength and increasing trend of the Young-s modulus with
increasing fiber content. During flexural, impact and hardness tests,
the flexural strength, flexural modulus, impact strength and hardness
were found to be increased with increasing fiber loading. Based on
the fiber loading used in this study, 20% fiber reinforced composite
resulted the best set of mechanical properties.
Abstract: Characteristics and sonocatalytic activity of zeolite
Y catalysts loaded with TiO2 using impregnation and ion exchange
methods for the degradation of amaranth dye were investigated.
The Ion-exchange method was used to encapsulate the TiO2 into
the internal pores of the zeolite while the incorporation of TiO2
mostly on the external surface of zeolite was carried out using the
impregnation method. Different characterization techniques were
used to elucidate the physicochemical properties of the produced
catalysts. The framework of zeolite Y remained virtually
unchanged after the encapsulation of TiO2 while the crystallinity of
zeolite decreased significantly after the incorporation of 15 wt% of
TiO2. The sonocatalytic activity was enhanced by TiO2
incorporation with maximum degradation efficiencies of 50% and
68% for the encapsulated titanium and titanium loaded onto the
zeolite, respectively after 120min of reaction. Catalysts
characteristics and sonocatalytic behaviors were significantly
affected by the preparation method and the location of TiO2
introduced with zeolite structure. Behaviors in the sonocatalytic
process were successfully correlated with the characteristics of the
catalysts used.
Abstract: The topic of surface flattening plays a vital role in the field of computer aided design and manufacture. Surface flattening enables the production of 2D patterns and it can be used in design and manufacturing for developing a 3D surface to a 2D platform, especially in fashion design. This study describes surface flattening based on minimum energy methods according to the property of different fabrics. Firstly, through the geometric feature of a 3D surface, the less transformed area can be flattened on a 2D platform by geodesic. Then, strain energy that has accumulated in mesh can be stably released by an approximate implicit method and revised error function. In some cases, cutting mesh to further release the energy is a common way to fix the situation and enhance the accuracy of the surface flattening, and this makes the obtained 2D pattern naturally generate significant cracks. When this methodology is applied to a 3D mannequin constructed with feature lines, it enhances the level of computer-aided fashion design. Besides, when different fabrics are applied to fashion design, it is necessary to revise the shape of a 2D pattern according to the properties of the fabric. With this model, the outline of 2D patterns can be revised by distributing the strain energy with different results according to different fabric properties. Finally, this research uses some common design cases to illustrate and verify the feasibility of this methodology.
Abstract: Business process model describes process flow of a
business and can be seen as the requirement for developing a
software application. This paper discusses a BPM2CD guideline
which complements the Model Driven Architecture concept by
suggesting how to create a platform-independent software model in
the form of a UML class diagram from a business process model. An
important step is the identification of UML classes from the business
process model. A technique for object-oriented analysis called
domain analysis is borrowed and key concepts in the business
process model will be discovered and proposed as candidate classes
for the class diagram. The paper enhances this step by using ontology
search to help identify important classes for the business domain. As
ontology is a source of knowledge for a particular domain which
itself can link to ontologies of related domains, the search can give a
refined set of candidate classes for the resulting class diagram.
Abstract: Evolutionary Algorithms are population-based,
stochastic search techniques, widely used as efficient global
optimizers. However, many real life optimization problems often
require finding optimal solution to complex high dimensional,
multimodal problems involving computationally very expensive
fitness function evaluations. Use of evolutionary algorithms in such
problem domains is thus practically prohibitive. An attractive
alternative is to build meta models or use an approximation of the
actual fitness functions to be evaluated. These meta models are order
of magnitude cheaper to evaluate compared to the actual function
evaluation. Many regression and interpolation tools are available to
build such meta models. This paper briefly discusses the
architectures and use of such meta-modeling tools in an evolutionary
optimization context. We further present two evolutionary algorithm
frameworks which involve use of meta models for fitness function
evaluation. The first framework, namely the Dynamic Approximate
Fitness based Hybrid EA (DAFHEA) model [14] reduces
computation time by controlled use of meta-models (in this case
approximate model generated by Support Vector Machine
regression) to partially replace the actual function evaluation by
approximate function evaluation. However, the underlying
assumption in DAFHEA is that the training samples for the metamodel
are generated from a single uniform model. This does not take
into account uncertain scenarios involving noisy fitness functions.
The second model, DAFHEA-II, an enhanced version of the original
DAFHEA framework, incorporates a multiple-model based learning
approach for the support vector machine approximator to handle
noisy functions [15]. Empirical results obtained by evaluating the
frameworks using several benchmark functions demonstrate their
efficiency
Abstract: Computations with higher than the IEEE 754 standard double-precision (about 16 significant digits) are required recently. Although there are available software routines in Fortran and C for high-precision computation, users are required to implement such routines in their own computers with detailed knowledges about them. We have constructed an user-friendly online system for octupleprecision computation. In our Web system users with no knowledges about high-precision computation can easily perform octupleprecision computations, by choosing mathematical functions with argument(s) inputted, by writing simple mathematical expression(s) or by uploading C program(s). In this paper we enhance the Web system above by adding the facility of uploading Fortran programs, which have been widely used in scientific computing. To this end we construct converter routines in two stages.
Abstract: Biometric techniques are gaining importance for
personal authentication and identification as compared to the
traditional authentication methods. Biometric templates are
vulnerable to variety of attacks due to their inherent nature. When a
person-s biometric is compromised his identity is lost. In contrast to
password, biometric is not revocable. Therefore, providing security
to the stored biometric template is very crucial. Crypto biometric
systems are authentication systems, which blends the idea of
cryptography and biometrics. Fuzzy vault is a proven crypto
biometric construct which is used to secure the biometric templates.
However fuzzy vault suffer from certain limitations like nonrevocability,
cross matching. Security of the fuzzy vault is affected
by the non-uniform nature of the biometric data. Fuzzy vault when
hardened with password overcomes these limitations. Password
provides an additional layer of security and enhances user privacy.
Retina has certain advantages over other biometric traits. Retinal
scans are used in high-end security applications like access control to
areas or rooms in military installations, power plants, and other high
risk security areas. This work applies the idea of fuzzy vault for
retinal biometric template. Multimodal biometric system
performance is well compared to single modal biometric systems.
The proposed multi modal biometric fuzzy vault includes combined
feature points from retina and fingerprint. The combined vault is
hardened with user password for achieving high level of security.
The security of the combined vault is measured using min-entropy.
The proposed password hardened multi biometric fuzzy vault is
robust towards stored biometric template attacks.
Abstract: The coalescer process is one of the methods for oily water treatment by increasing the oil droplet size in order to enhance the separating velocity and thus effective separation. However, the presence of surfactants in an oily emulsion can limit the obtained mechanisms due to the small oil size related with stabilized emulsion. In this regard, the purpose of this research is to improve the efficiency of the coalescer process for treating the stabilized emulsion. The effects of bed types, bed height, liquid flow rate and stage coalescer (step-bed) on the treatment efficiencies in term of COD values were studied. Note that the treatment efficiency obtained experimentally was estimated by using the COD values and oil droplet size distribution. The study has shown that the plastic media has more effective to attach with oil particles than the stainless one due to their hydrophobic properties. Furthermore, the suitable bed height (3.5 cm) and step bed (3.5 cm with 2 steps) were necessary in order to well obtain the coalescer performance. The application of step bed coalescer process in reactor has provided the higher treatment efficiencies in term of COD removal than those obtained with classical process. The proposed model for predicting the area under curve and thus treatment efficiency, based on the single collector efficiency (ηT) and the attachment efficiency (α), provides relatively a good coincidence between the experimental and predicted values of treatment efficiencies in this study.
Abstract: Web usage mining has become a popular research
area, as a huge amount of data is available online. These data can be
used for several purposes, such as web personalization, web structure
enhancement, web navigation prediction etc. However, the raw log
files are not directly usable; they have to be preprocessed in order to
transform them into a suitable format for different data mining tasks.
One of the key issues in the preprocessing phase is to identify web
users. Identifying users based on web log files is not a
straightforward problem, thus various methods have been developed.
There are several difficulties that have to be overcome, such as client
side caching, changing and shared IP addresses and so on. This paper
presents three different methods for identifying web users. Two of
them are the most commonly used methods in web log mining
systems, whereas the third on is our novel approach that uses a
complex cookie-based method to identify web users. Furthermore we
also take steps towards identifying the individuals behind the
impersonal web users. To demonstrate the efficiency of the new
method we developed an implementation called Web Activity
Tracking (WAT) system that aims at a more precise distinction of
web users based on log data. We present some statistical analysis
created by the WAT on real data about the behavior of the Hungarian
web users and a comprehensive analysis and comparison of the three
methods
Abstract: Energy efficient protocol design is the aim of current
researches in the area of sensor networks where limited power
resources impose energy conservation considerations. In this paper
we care for Medium Access Control (MAC) protocols and after an
extensive literature review, two adaptive schemes are discussed. Of
them, adaptive-rate MACs which were introduced for throughput
enhancement show the potency to save energy, even more than
adaptive-power schemes. Then we propose an allocation algorithm
for getting accurate and reliable results. Through a simulation study
we validated our claim and showed the power saving of adaptive-rate
protocols.
Abstract: This paper presents a generalized formulation for the
problem of buckling optimization of anisotropic, radially graded,
thin-walled, long cylinders subject to external hydrostatic pressure.
The main structure to be analyzed is built of multi-angle fibrous
laminated composite lay-ups having different volume fractions of the
constituent materials within the individual plies. This yield to a
piecewise grading of the material in the radial direction; that is the
physical and mechanical properties of the composite material are
allowed to vary radially. The objective function is measured by
maximizing the critical buckling pressure while preserving the total
structural mass at a constant value equals to that of a baseline
reference design. In the selection of the significant optimization
variables, the fiber volume fractions adjoin the standard design
variables including fiber orientation angles and ply thicknesses. The
mathematical formulation employs the classical lamination theory,
where an analytical solution that accounts for the effective axial and
flexural stiffness separately as well as the inclusion of the coupling
stiffness terms is presented. The proposed model deals with
dimensionless quantities in order to be valid for thin shells having
arbitrary thickness-to-radius ratios. The critical buckling pressure
level curves augmented with the mass equality constraint are given
for several types of cylinders showing the functional dependence of
the constrained objective function on the selected design variables. It
was shown that material grading can have significant contribution to
the whole optimization process in achieving the required structural
designs with enhanced stability limits.
Abstract: In this study, we experiment on precise control outlet
temperature of water from the water cooler with hot-gas bypass
method based on PI control logic for machine tool. Recently, technical
trend for machine tools is focused on enhancement of speed and
accuracy. High speedy processing causes thermal and structural
deformation of objects from the machine tools. Water cooler has to be
applied to machine tools to reduce the thermal negative influence with
accurate temperature controlling system. The goal of this study is to
minimize temperature error in steady state. In addition, control period
of an electronic expansion valve were considered to increment of
lifetime of the machine tools and quality of product with a water
cooler.
Abstract: Enhancement of the performance of a reverse osmosis
(RO) unit through periodic control is studied. The periodic control
manipulates the feed pressure and flow rate of the RO unit. To ensure
the periodic behavior of the inputs, the manipulated variables (MV)
are transformed into the form of sinusoidal functions. In this case, the
amplitude and period of the sinusoidal functions become the
surrogate MV and are thus regulated via nonlinear model predictive
control algorithm. The simulation results indicated that the control
system can generate cyclic inputs necessary to enhance the closedloop
performance in the sense of increasing the permeate production
and lowering the salt concentration. The proposed control system can
attain its objective with arbitrary set point for the controlled outputs.
Successful results were also obtained in the presence of modeling
errors.
Abstract: Periodic vortex shedding in pulsating flow inside wavy
channel and the effect it has on heat transfer are studied using the
finite volume method. A sinusoidally-varying component is superimposed
on a uniform flow inside a sinusoidal wavy channel and
the effects on the Nusselt number is analyzed. It was found that a
unique optimum value of the pulsation frequency, represented by the
Strouhal number, exists for Reynolds numbers ranging from 125 to
1000. Results suggest that the gain in heat transfer is related to the
process of vortex formation, movement about the troughs of the wavy
channel, and subsequent ejection/destruction through the converging
section. Heat transfer is the highest when the frequencies of the
pulsation and vortex formation approach being in-phase. Analysis of
Strouhal number effect on Nu over a period of pulsation substantiates
the proposed physical mechanism for enhancement. The effect of
changing the amplitude of pulsation is also presented over a period
of pulsation, showing a monotonic increase in heat transfer with
increasing amplitude. The 60% increase in Nusselt number suggests
that sinusoidal fluid pulsation can an effective method for enhancing
heat transfer in laminar, wavy-channel flows.
Abstract: Application of nanoparticles as additives in membrane
synthesis for improving the resistance of membranes against fouling
has triggered recent interest in new membrane types. However, most
nanoparticle-enhanced membranes suffer from the tradeoff between
permeability and selectivity. In this study, nano-WS2 was explored as
the additive in membrane synthesis by non-solvent induced phase
separation. Blended PES-WS2 flat-sheet membranes with the
incorporation of ultra-low concentrations of nanoparticles (from 0.025
to 0.25%, WS2/PES ratio) were manufactured and investigated in
terms of permeability, fouling resistance and solute rejection.
Remarkably, a significant enhancement in the permeability was
observed as a result of the incorporation of ultra-low fractions of
nano-WS2 to the membrane structure. Optimal permeability values
were obtained for modified membranes with 0.10%
nanoparticle/polymer concentration ratios. Furthermore, fouling
resistance and solute rejection were significantly improved by the
incorporation of nanoparticles into the membrane matrix. Specifically,
fouling resistance of modified membrane can increase by around 50%.
Abstract: In this study, we explore the use of information for inventory decision in the healthcare organization (HO). We consider the scenario when the HO can make use of the information collected from some correlated products to enhance its inventory planning. Motivated by our real world observations that HOs adopt RFID and bar-coding system for information collection purpose, we examine the effectiveness of these systems for inventory planning with Bayesian information updating. We derive the optimal ordering decision and study the issue of Pareto improvement in the supply chain. Our analysis demonstrates that RFID system will outperform the bar-coding system when the RFID system installation cost and the tag cost reduce to a level that is comparable with that of the barcoding system. We also show how an appropriately set wholesale pricing contract can achieve Pareto improvement in the HO supply chain.
Abstract: With the increase of economic behavior and the upgrade
of living standar, the ratio for people in Taiwan who own automobiles
and motorcycles have recently increased with multiples. Therefore,
parking issues will be a big challenge to facilitate traffic network and
ensure urban life quality. The Parking Guidance and Information
System is one of important systems for Advanced Traveler Information
Services (ATIS). This research proposes a parking guidance and
information system which integrates GPS and 3G network for a map on
the Geographic Information System to solution inadequate of roadside
information kanban. The system proposed in this study mainly includes
Parking Host, Parking Guidance and Information Server, Geographic
Map and Information System as well as Parking Guidance and
Information Browser. The study results show this system can increase
driver-s efficiency to find parking space and efficiently enhance
parking convenience in comparison with roadside kanban system.
Abstract: Liposomal magnetofection is the most powerful nonviral method for the nucleic acid delivery into the cultured cancer cells and widely used for in vitro applications. Use of the static magnetic field condition may result in non-uniform distribution of aggregate complexes on the surface of cultured cells. To prevent this, we developed the new device which allows to concentrate aggregate complexes under dynamic magnetic field, assisting more contact of these complexes with cellular membrane and, possibly, stimulating endocytosis. Newly developed device for magnetofection under dynamic gradient magnetic field, “DynaFECTOR", was used to compare transfection efficiency of human liver hepatocellular carcinoma cell line HepG2 with that obtained by lipofection and magnetofection. The effect of two parameters on transfection efficiency, incubation time under dynamic magnetic field and rotation frequency of magnet, was estimated. Liposomal magnetofection under dynamic gradient magnetic field showed the highest transfection efficiency for HepG2 cells.