Abstract: The two-dimensional gel electrophoresis method
(2-DE) is widely used in Proteomics to separate thousands of proteins
in a sample. By comparing the protein expression levels of proteins in
a normal sample with those in a diseased one, it is possible to identify
a meaningful set of marker proteins for the targeted disease. The major
shortcomings of this approach involve inherent noises and irregular
geometric distortions of spots observed in 2-DE images. Various
experimental conditions can be the major causes of these problems. In
the protein analysis of samples, these problems eventually lead to
incorrect conclusions. In order to minimize the influence of these
problems, this paper proposes a partition based pair extension method
that performs spot-matching on a set of gel images multiple times and
segregates more reliable mapping results which can improve the
accuracy of gel image analysis. The improved accuracy of the
proposed method is analyzed through various experiments on real
2-DE images of human liver tissues.
Abstract: The aim of this study is to examine the reading
comprehension scores of Turkish 5th grade students according to the
variables given in the student questionnaire. In this descriptive
survey study research participated 279 5th grade students, who
studied at 10 different primary schools in four provinces of Ankara in
2008-2009 academic year. Two different data collection tools were
made use of in the study: “Reading Comprehension Test" and
“Student Information Questionnaire". Independent sample t-test, oneway
Anova and two-way Anova tests were used in the analyses of
the gathered data. The results of the study indicate that the reading
comprehension scores of the students differ significantly according to
sex of the students, the number of books in their houses, the
frequency of summarizing activities on the reading text of free and
the frequency reading hours provided by their teachers; but, differ
not significantly according to educational level of their mothers and
fathers.
Abstract: In this paper, penalized power-divergence test statistics have been defined and their exact size properties to test a nested sequence of log-linear models have been compared with ordinary power-divergence test statistics for various penalization, λ and main effect values. Since the ordinary and penalized power-divergence test statistics have the same asymptotic distribution, comparisons have been only made for small and moderate samples. Three-way contingency tables distributed according to a multinomial distribution have been considered. Simulation results reveal that penalized power-divergence test statistics perform much better than their ordinary counterparts.
Abstract: The coastal sediments of West Port of Malaysia was monitored from Nov. 2009 to Oct. 2010 to assess spatial distribution of heavy metals As, Cu, Cd, Cr, Hg, Ni, Zn and Pb. Sediment samples were collected from 10 stations in dry and rainy season in West Port. The range concentrations measured (Mg/g dry weight ) were from 23.4 to 98.3 for Zn, 22.3 to 80 for Pb, 7.4 to 27.6 Cu, 0.244 to 3.53 for Cd, 7.2 to 22.2 for Ni, 20.2 to 162 for As, 0.11 to 0.409 for Hg and 11.5 to 61.5 for Cr. The geochemical indexes used in this study were Geoaccumulation (Igeo), Contamination Factor (CF) and Pollution Load Index (PLI); these indexes were used to evaluate the levels of sediment contaminations. The results of these indexes show that, the status of West Port sediment quality are moderately polluted by heavy metals except in arsenic which shows the high level of pollution.
Abstract: Ranked set sampling (RSS) was first suggested to increase the efficiency of the population mean. It has been shown that this method is highly beneficial to the estimation based on simple random sampling (SRS). There has been considerable development and many modifications were done on this method. When a concomitant variable is available, ratio estimation based on ranked set sampling was proposed. This ratio estimator is more efficient than that based on SRS. In this paper some ratio type estimators of the population mean based on RSS are suggested. These estimators are found to be more efficient than the estimators of similar form using simple random sample.
Abstract: Simultaneous effects of temperature, immersion time, salt concentration, sucrose concentration, pressure and convective dryer temperature on the combined osmotic dehydration - convective drying of edible button mushrooms were investigated. Experiments were designed according to Central Composite Design with six factors each at five different levels. Response Surface Methodology (RSM) was used to determine the optimum processing conditions that yield maximum water loss and rehydration ratio and minimum solid gain and shrinkage in osmotic-convective drying of edible button mushrooms. Applying surfaces profiler and contour plots optimum operation conditions were found to be temperature of 39 °C, immersion time of 164 min, salt concentration of 14%, sucrose concentration of 53%, pressure of 600 mbar and drying temperature of 40 °C. At these optimum conditions, water loss, solid gain, rehydration ratio and shrinkage were found to be 63.38 (g/100 g initial sample), 3.17 (g/100 g initial sample), 2.26 and 7.15%, respectively.
Abstract: The quality and shelf life of foods of containing lipids (fats and oils) significantly reduces due to rancidity.Applications of natural antioxidants are one of the most effective manners to prevent the oxidation of oils and lipids. The antioxidant properties of juice extracted from barberry fruit (Berberris vulgaris.L) using maceration and SWE (10 bars and 120 - 180°C) methods were investigated and compared with conventional method. The amount of phenolic compound and reduction power of all samples were determined and the data were statistically analyzed using multifactor design. The results showed that the total amount of phenolic compound increased with increasing of pressure and temprature from 1861.9 to 2439.1 (mg Gallic acid /100gr Dry matter). The ability of reduction power of SWE obtained antioxidant extract compared with BHA (synthetic antioxidant) and ascorbic acid (natural antioxidant). There were significant differences among reduction power of extracts and there were remarkable difference with BHA and Ascorbic acid (P
Abstract: With the intention of screening for heavy metal
tolerance, a number of bacteria were isolated and characterized from
a pristine soil. Two Gram positive isolates were identified as
Paenibacillus sp. and Bacillus thuringeinsis. Tolerance of Cd2+, Cu2+
and Zn2+ by these bacteria was studied and found that both bacteria
were highly sensitive to Cu2+ compared to other two metals. Both
bacteria showed the same pattern of metal tolerance in the order Zn+
> Cd2+ > Cu2+. When the metal tolerance in both bacteria was
compared, Paenibacillus sp. showed the highest sensitivity to Cu2+
where as B. thuringiensis showed highest sensitivity to Cd2+ and Zn2+
.These findings revealed the potential of Paenibacillus sp. in
developing a biosensor to detect Cu2+ in environmental samples.
Abstract: This paper investigates the effect of International
Financial Reporting Standards (IFRS) adoption on the frequency of
earnings managements towards small positive profits. We focus on
two emerging markets IFRS adopters: South Africa and Turkey.
We tested our logistic regression using appropriate panelestimation
techniques over a sample of 330 South African and 210
Turkish firm-year observations over the period 2002-2008. Our
results document that mandatory adoption of IFRS is not associated
with a reduction in earnings management towards small positive
profits in emerging markets. These results contradict most of the
previous findings of the studies conducted in developed countries.
Based on the legal system factor, we compare the intensity of
earnings management between a code law country (Turkey) and a
common law country (South Africa) over the pre and post-adoption
periods. Our findings show that the frequency of such earnings
management practice increases significantly for the code law
country.
Abstract: Microarray data profiles gene expression on a whole
genome scale, therefore, it provides a good way to study associations
between gene expression and occurrence or progression of cancer.
More and more researchers realized that microarray data is helpful
to predict cancer sample. However, the high dimension of gene
expressions is much larger than the sample size, which makes this
task very difficult. Therefore, how to identify the significant genes
causing cancer becomes emergency and also a hot and hard research
topic. Many feature selection algorithms have been proposed in
the past focusing on improving cancer predictive accuracy at the
expense of ignoring the correlations between the features. In this
work, a novel framework (named by SGS) is presented for stable gene
selection and efficient cancer prediction . The proposed framework
first performs clustering algorithm to find the gene groups where
genes in each group have higher correlation coefficient, and then
selects the significant genes in each group with Bayesian Lasso and
important gene groups with group Lasso, and finally builds prediction
model based on the shrinkage gene space with efficient classification
algorithm (such as, SVM, 1NN, Regression and etc.). Experiment
results on real world data show that the proposed framework often
outperforms the existing feature selection and prediction methods,
say SAM, IG and Lasso-type prediction model.
Abstract: Names are important in many societies, even in technologically oriented ones which use e.g. ID systems to identify individual people. Names such as surnames are the most important as they are used in many processes, such as identifying of people and genealogical research. On the other hand variation of names can be a major problem for the identification and search for people, e.g. web search or security reasons. Name matching presumes a-priori that the recorded name written in one alphabet reflects the phonetic identity of two samples or some transcription error in copying a previously recorded name. We add to this the lode that the two names imply the same person. This paper describes name variations and some basic description of various name matching algorithms developed to overcome name variation and to find reasonable variants of names which can be used to further increasing mismatches for record linkage and name search. The implementation contains algorithms for computing a range of fuzzy matching based on different types of algorithms, e.g. composite and hybrid methods and allowing us to test and measure algorithms for accuracy. NYSIIS, LIG2 and Phonex have been shown to perform well and provided sufficient flexibility to be included in the linkage/matching process for optimising name searching.
Abstract: The curriculum of the primary school science course was redesigned on the basis of constructivism in 2005-2006 academic years, in Turkey. In this context, the name of this course has been changed as “Science and Technology"; and both content and course books, students workbooks for this course have been redesigned in light of constructivism. The aim of this study is to determine whether the Science and Technology course books and student work books for primary school 5th grade are appropriate for the constructivism by evaluating them in terms of the fundamental principles of constructivism. In this study, out of qualitative research methods, documentation technique (i.e. document analysis) is applied; while selecting samples, criterion-sampling is used out of purposeful sampling techniques. When the Science and Technology course book and workbook for the 5th grade in primary education are examined, it is seen that both books complete each other in certain areas. Consequently, it can be claimed that in spite of some inadequate and missing points in the course book and workbook of the primary school Science and Technology course for the 5th grade students, these books are attempted to be designed in terms of the principles of constructivism. To overcome the inadequacies in the books, it can be suggested to redesign them. In addition to them, not to ignore the technology dimension of the course, the activities that encourage the students to prepare projects using technology cycle should be included.
Abstract: Developing an accurate classifier for high dimensional microarray datasets is a challenging task due to availability of small sample size. Therefore, it is important to determine a set of relevant genes that classify the data well. Traditionally, gene selection method often selects the top ranked genes according to their discriminatory power. Often these genes are correlated with each other resulting in redundancy. In this paper, we have proposed a hybrid method using feature ranking and wrapper method (Genetic Algorithm with multiclass SVM) to identify a set of relevant genes that classify the data more accurately. A new fitness function for genetic algorithm is defined that focuses on selecting the smallest set of genes that provides maximum accuracy. Experiments have been carried on four well-known datasets1. The proposed method provides better results in comparison to the results found in the literature in terms of both classification accuracy and number of genes selected.
Abstract: Water vapour transport properties of gypsum block
are studied in dependence on relative humidity using inverse analysis
based on genetic algorithm. The computational inverse analysis is
performed for the relative humidity profiles measured along the
longitudinal axis of a rod sample. Within the performed transient
experiment, the studied sample is exposed to two environments with
different relative humidity, whereas the temperature is kept constant.
For the basic gypsum characterisation and for the assessment of input
material parameters necessary for computational application of
genetic algorithm, the basic material properties of gypsum are
measured as well as its thermal and water vapour storage parameters.
On the basis of application of genetic algorithm, the relative
humidity dependent water vapour diffusion coefficient and water
vapour diffusion resistance factor are calculated.
Abstract: Chemical and physical functionalization of multiwalled
carbon nanotubes (MWCNT) has been commonly practiced to
achieve better dispersion of carbon nanotubes (CNTs) in polymer
matrix. This work describes various functionalization methods (acidtreatment,
non-ionic surfactant treatment with TritonX-100),
fabrication of MWCNT/PP nanocomposites via melt blending and
characterization of mechanical properties. Microscopy analysis
(FESEM, TEM, XPS) showed effective purification of MWCNTs
under acid treatment, and better dispersion under both chemical and
physical functionalization techniques combined, in their respective
order. Tensile tests showed increase in tensile strength for the
nanocomposites that contain MWCNTs up to 2 wt%. A decrease in
tensile strength was seen in samples that contain 4 wt% of MWCNTs
for both raw and Triton X-100 functionalized, signifying MWCNT
degradation/rebundling at composition with higher content of
MWCNTs. For the acid-treated MWCNTs, however, the tensile
results showed slight improvement even at 4wt%, indicating effective
dispersion of MWCNTs.
Abstract: In this paper we address the issue of classifying the fluorescent intensity of a sample in Indirect Immuno-Fluorescence (IIF). Since IIF is a subjective, semi-quantitative test in its very nature, we discuss a strategy to reliably label the image data set by using the diagnoses performed by different physicians. Then, we discuss image pre-processing, feature extraction and selection. Finally, we propose two ANN-based classifiers that can separate intrinsically dubious samples and whose error tolerance can be flexibly set. Measured performance shows error rates less than 1%, which candidates the method to be used in daily medical practice either to perform pre-selection of cases to be examined, or to act as a second reader.
Abstract: In this study, Li4SiO4 powder was successfully
synthesized via sol gel method followed by drying at 150oC. Lithium
oxide, Li2O and silicon oxide, SiO2 were used as the starting
materials with citric acid as the chelating agent. The obtained powder
was then sintered at various temperatures. Crystallographic phase
analysis, morphology and ionic conductivity were investigated
systematically employing X-ray diffraction, Fourier Transform
Infrared, Scanning Electron Microscopy and AC impedance
spectroscopy. XRD result showed the formation of pure monoclinic
Li4SiO4 crystal structure with lattice parameters a = 5.140 Å, b =
6.094 Å, c = 5.293 Å, β = 90o in the sample sintered at 750oC. This
observation was confirmed by FTIR analysis. The bulk conductivity
of this sample at room temperature was 3.35 × 10-6 S cm-1 and the
highest bulk conductivity of 1.16 × 10-4 S cm-1 was obtained at
100°C. The results indicated that, the Li4SiO4 compound has
potential to be used as host for LISICON structured solid electrolyte
for low temperature application.
Abstract: The increasing interest in plant sterol enriched foods
is due to the fact that they reduce blood cholesterol concentrations
without adverse side effects. In this context, enriched foods with
phytosterols may be helpful in protecting population against
atherosclerosis and cardiovascular diseases. The aim of the present
work was to evaluate in a population of Viseu, Portugal, the
consumption habits low-fat, plant sterol-enriched yoghurt. For this
study, 577 inquiries were made and the sample was randomly
selected for people shopping in various supermarkets. The
preliminary results showed that the biggest consumers of these
products were women aged 45 to 65 years old. Most of the people
who claimed to buy these products consumed them once a day. Also,
most of the consumers under antidyslipidemic therapeutics noticed
positive effects on hypercholesterolemia.
Abstract: Food safety is an important concern for holiday
makers in foreign and unfamiliar tourist destinations. In fact, risk
from food in these tourist destinations has an influence on tourist
perception. This risk can potentially affect physical health and lead to
an inability to pursue planned activities. The objective of this paper
was to compare foreign tourists- demographics including gender, age
and education level, with the level of perceived risk towards food
safety. A total of 222 foreign tourists during their stay at Khao San
Road in Bangkok were used as the sample. Independent- samples ttest,
analysis of variance, and Least Significant Difference or LSD
post hoc test were utilized. The findings revealed that there were few
demographic differences in level of perceived risk among the foreign
tourists. The post hoc test indicated a significant difference among
the old and the young tourists, and between the higher and lower
level of education. Ranks of tourists- perceived risk towards food
safety unveiled some interesting results. Tourists- perceived risk of
food safety in established restaurants can be ranked as i) cleanliness
of dining utensils, ii) sanitation of food preparation area, and iii)
cleanliness of food seasoning and ingredients. Whereas, the tourists-
perceived risk of food safety in street food and drink can be ranked
as i) cleanliness of stalls and pushcarts, ii) cleanliness of food sold,
and iii) personal hygiene of street food hawkers or vendors.
Abstract: In this study, an investigation over digestive diseases has been done in which the sound acts as a detector medium. Pursue to the preprocessing the extracted signal in cepstrum domain is registered. After classification of digestive diseases, the system selects random samples based on their features and generates the interest nonstationary, long-term signals via inverse transform in cepstral domain which is presented in digital and sonic form as the output. This structure is updatable or on the other word, by receiving a new signal the corresponding disease classification is updated in the feature domain.