Abstract: Tumor classification is a key area of research in the
field of bioinformatics. Microarray technology is commonly used in
the study of disease diagnosis using gene expression levels. The
main drawback of gene expression data is that it contains thousands
of genes and a very few samples. Feature selection methods are used
to select the informative genes from the microarray. These methods
considerably improve the classification accuracy. In the proposed
method, Genetic Algorithm (GA) is used for effective feature
selection. Informative genes are identified based on the T-Statistics,
Signal-to-Noise Ratio (SNR) and F-Test values. The initial candidate
solutions of GA are obtained from top-m informative genes. The
classification accuracy of k-Nearest Neighbor (kNN) method is used
as the fitness function for GA. In this work, kNN and Support Vector
Machine (SVM) are used as the classifiers. The experimental results
show that the proposed work is suitable for effective feature
selection. With the help of the selected genes, GA-kNN method
achieves 100% accuracy in 4 datasets and GA-SVM method
achieves in 5 out of 10 datasets. The GA with kNN and SVM
methods are demonstrated to be an accurate method for microarray
based tumor classification.
Abstract: In Both developed and developing countries,
governments play a basic role in making policies, programs and
instruments which support the development of micro, small and
medium enterprises. One of the mechanisms employed to nurture
small firms for more than two decades is business incubation. One of
the mechanisms employed to nurture small firms for more than two
decades is technology business incubation. The main aim of this
research was to establish influencing factors in Technology Business
Incubator's effectiveness and their explanatory model. Therefore,
among 56 Technology Business Incubators in Iran, 32 active
incubators were selected and by stratified random sampling, 528
start-ups were chosen. The validity of research questionnaires
was determines by expert consensus, item analysis and factor
analysis; and their reliability calculated by Cronbach-s alpha.
Data analysis was then made through SPSS and LISREL soft wares.
Both organizational procedures and entrepreneurial behaviors were
the meaningful mediators. Organizational procedures with (P < .01, β
=0.45) was stronger mediator for the improvement of Technology
Business Incubator's effectiveness comparing to entrepreneurial
behavior with (P < .01, β =0.36).
Abstract: Without uncertainty by applying external loads on
beams, bending is created. The created bending in I-beams, puts one
of the flanges in tension and the other one in compression. With increasing of bending, compression flange buckled and beam in out
of its plane direction twisted, this twisting well-known as Lateral Torsional Buckling. Providing bending moment varieties along the
beam, the critical moment is greater than the case its under pure bending. In other words, the value of bending gradient coefficient is
always greater than unite. In this article by the use of " ANSYS 10.0" software near 80 3-D finite element models developed for the
propose of analyzing beams` lateral torsional buckling and surveying influence of slenderness on beams' bending gradient coefficient.
Results show that, presented Cb coefficient via AISC is not correct for some of beams and value of this coefficient is smaller than what proposed by AISC. Therefore instead of using a constant Cb for each
case of loading , a function with two criterion for calculation of Cb coefficient for some cases is proposed.
Abstract: At present, the severe oil crisis and greenhouse effect are booming, which is a growing worry for China. Over a long period of study, choosing the development of biological diesel is a feasible way in the desertification region in China. With considering the adaptability of Micro-algae in desertification region and analyzing energy consumption and carbon calculations of Micro-algae biodiesel produced by JJ company , this paper, make the microalgae our optimal choice to develop biological diesel in china's desertification region.
Abstract: The relevance of the study of everyday life in Almaty
and Kyzylorda are associated with the emergence of the modern
trends in historiography and socializing areas of government reform.
The relevance is due to the fact that in the early twentieth century
Kyzylorda and Almaty began to develop as a city and this period has
a special place in the life of the state. An interesting aspect of the
everyday life of the inhabitants of the new city, which was built in the
era of Stalin's Five-Year Plans, can be examined through the eyes of
the Soviet people living in a specific environment, reflecting the life
of the citizens. The study of industrialization of the Soviet Union and
the attention paid to new developments in the first five years of
everyday aspects as the impact of the modernization of the 1930s was
one of the decisive factors in the lives of residents. Among these
factors, we would like to highlight the medical field, which is the
basis of all human life, specifically focusing on the state of medicine
in Alma-Ata in the first 20-30-years of the twentieth century, and
analyze the different aspects of human life, determining the quality of
medical care to the population during this period.
Abstract: COSMED K4b2 is a portable electrical device designed to test pulmonary functions. It is ideal for many applications that need the measurement of the cardio-respiratory response either in the field or in the lab is capable with the capability to delivery real time data to a sink node or a PC base station with storing data in the memory at the same time. But the actual sensor outputs and data received may contain some errors, such as impulsive noise which can be related to sensors, low batteries, environment or disturbance in data acquisition process. These abnormal outputs might cause misinterpretations of exercise or living activities to persons being monitored. In our paper we propose an effective and feasible method to detect and identify errors in applications by principal component analysis (PCA) and a back propagation (BP) neural network.
Abstract: The inhibition effect of brazilin to human bladder
tumor cell line T24 in vitro and in vivo was studied. The results of the
in vitro experiments showed that brazilin has strong inhibition activity
on the target cells. The inhibition ratio of 100 μg/mL brazilin and 100
μg/mL mitomycin to the target cells was 90.90 % and 63.24 %
respectively, which showed that brazilin has higher inhibition activity
than mitomycin under the same concentration. Brazilin could induce
cell apoptosis in T24 cells. Significant antitumor activity of brazilin
was also showed in the animals experiments. The life extention rate of
200 mg/mL, 300 mg/kg, and 400 mg/kg brazilin intraperitoneally
injected into Balb/c-nu-nu nude mice that with human bladder cancer
were 51.50 %, 56.90 %, and 58.42 %（P
Abstract: To achieve the desired specifications of gain and
phase margins for plants with time-delay that stabilized with FO-PID
controller a lead compensator is designed. At first the range of
controlled system stability based on stability boundary criteria is
determined. Using stability boundary locus method in frequency
domain the fractional order controller parameters are tuned and then
with drawing bode diagram in frequency domain accessing to desired
gain and phase margin are shown. Numerical examples are given to
illustrate the shapes of the stabilizing region and to show the design
procedure.
Abstract: Petri Net being one of the most useful graphical tools for modelling complex asynchronous systems, we have used Petri Net to model multi-track railway level crossing system. The roadway has been augmented with four half-size barriers. For better control, a three stage control mechanism has been introduced to ensure that no road-vehicle is trapped on the level crossing. Timed Petri Net is used to include the temporal nature of the signalling system. Safeness analysis has also been included in the discussion section.
Abstract: Starting with an analysis of the financial and
operational indicators that can be found in the specialised literature,
this study aims to contribute to improvements in the performance
measurement systems used when the unit of analysis is the
manufacturing plant. For this a search was done in the highest impact
Journals of Production and Operations Management and
Management Accounting , with the aim of determining the financial
and operational indicators used to evaluate performance when
Advanced Production Practices have been implemented, more
specifically when the practices implemented are Total Quality
Management, JIT/Lean Manufacturing and Total Productive
Maintenance. This has enabled us to obtain a classification of the two
types of indicators based on how much each is used. For the financial
indicators we have also prepared a proposal that can be adapted to
manufacturing plants- accounting features. In the near future we will
propose a model that links practices implementation with financial
and operational indicators and these two last with each other. We aim
to will test this model empirically with the data obtained in the High
Performance Manufacturing Project.
Abstract: We present a new numerical method for the computation of the steady-state solution of Markov chains. Theoretical analyses show that the proposed method, with a contraction factor α, converges to the one-dimensional null space of singular linear systems of the form Ax = 0. Numerical experiments are used to illustrate the effectiveness of the proposed method, with applications to a class of interesting models in the domain of tandem queueing networks.
Abstract: In July 1, 2007, Taiwan Stock Exchange (TWSE) on
market observation post system (MOPS) adds a new "Financial
reference database" for investors to do investment reference. This
database as a warning to public offering companies listed on the
public financial information and it original within eight targets. In
this paper, this database provided by the indicators for the application
of company financial crisis early warning model verify that the
database provided by the indicator forecast for the financial crisis,
whether or not companies have a high accuracy rate as opposed to
domestic and foreign scholars have positive results. There is use of
Logistic Regression Model application of the financial early warning
model, in which no joined back-conditions is the first model, joined it
in is the second model, has been taken occurred in the financial crisis
of companies to research samples and then business took place
before the financial crisis point with T-1 and T-2 sample data to do
positive analysis. The results show that this database provided the
debt ratio and net per share for the best forecast variables.
Abstract: This paper mainly investigates the environmental and
economic impacts of worldwide use of electric vehicles. It can be
concluded that governments have good reason to promote the use of
electric vehicles. First, the global vehicles population is evaluated with
the help of grey forecasting model and the amount of oil saving is
estimated through approximate calculation. After that, based on the
game theory, the amount and types of electricity generation needed by
electronic vehicles are established. Finally, some conclusions on the
government-s attitudes are drawn.
Abstract: In this paper, first we introduce the stable distribution, stable process and theirs characteristics. The a -stable distribution family has received great interest in the last decade due to its success in modeling data, which are too impulsive to be accommodated by the Gaussian distribution. In the second part, we propose major applications of alpha stable distribution in telecommunication, computer science such as network delays and signal processing and financial markets. At the end, we focus on using stable distribution to estimate measure of risk in stock markets and show simulated data with statistical softwares.
Abstract: This paper deals with a design method of a discrete
modified Internal Model Control (IMC) for a plant with an integrator
and dead time. If there is a load disturbance in the input or output side
of the plant, the proposed control system can eliminate the steady-state
error caused by it. The disturbance compensator in this method is
simple and its order is low regardless of that of a plant. The simulation
studies show that the proposed method has superior performance for a
load disturbance rejection and robustness.
Abstract: It has become crucial over the years for nations to
improve their credit scoring methods and techniques in light of the
increasing volatility of the global economy. Statistical methods or
tools have been the favoured means for this; however artificial
intelligence or soft computing based techniques are becoming
increasingly preferred due to their proficient and precise nature and
relative simplicity. This work presents a comparison between Support
Vector Machines and Artificial Neural Networks two popular soft
computing models when applied to credit scoring. Amidst the
different criteria-s that can be used for comparisons; accuracy,
computational complexity and processing times are the selected
criteria used to evaluate both models. Furthermore the German credit
scoring dataset which is a real world dataset is used to train and test
both developed models. Experimental results obtained from our study
suggest that although both soft computing models could be used with
a high degree of accuracy, Artificial Neural Networks deliver better
results than Support Vector Machines.
Abstract: This paper attempts to discuss the spam issue from the Malaysian e-mail users- perspective. The purpose is to discover how Malaysian users handle the spam e-mail problem. From the experiences we hope to discover the necessary effort needed to be undertaken to face this problem in the context of Malaysia. A survey was conducted to understand how Malaysian individual perceived spam and what they actually do with the spam e-mail they received in their daily life. The findings indicate that the level of awareness on spam issue in action is still low and need some extra effort by government and relevant agencies to increase their level of awareness.
Abstract: This paper presents two prototypes of low power low voltage current mode 9 bit pipelined a/d converters. The first and the second converters are configured of 1.5 bit and 2.5 bit stages, respectively. The a/d converter structures are composed of current mode building blocks and final comparator block which converts the analog current signal into digital voltage signal. All building blocks have been designed in CMOS AMS 0.35μm technology, then simulated to verify proposed concept. The performances of both converters are compared to performances of known current mode and voltage mode switched capacitance converter structures. Low power consumption and small chip area are advantages of the proposed converters.
Abstract: If there exists a nonempty, proper subset S of the set of all (n + 1)(n + 2)/2 inertias such that S Ôèå i(A) is sufficient for any n × n zero-nonzero pattern A to be inertially arbitrary, then S is called a critical set of inertias for zero-nonzero patterns of order n. If no proper subset of S is a critical set, then S is called a minimal critical set of inertias. In [3], Kim, Olesky and Driessche identified all minimal critical sets of inertias for 2 × 2 zero-nonzero patterns. Identifying all minimal critical sets of inertias for n × n zero-nonzero patterns with n ≥ 3 is posed as an open question in [3]. In this paper, all minimal critical sets of inertias for 3 × 3 zero-nonzero patterns are identified. It is shown that the sets {(0, 0, 3), (3, 0, 0)}, {(0, 0, 3), (0, 3, 0)}, {(0, 0, 3), (0, 1, 2)}, {(0, 0, 3), (1, 0, 2)}, {(0, 0, 3), (2, 0, 1)} and {(0, 0, 3), (0, 2, 1)} are the only minimal critical sets of inertias for 3 × 3 irreducible zerononzero patterns.
Abstract: This paper presents a Reliability-Based Topology
Optimization (RBTO) based on Evolutionary Structural Optimization
(ESO). An actual design involves uncertain conditions such as
material property, operational load and dimensional variation.
Deterministic Topology Optimization (DTO) is obtained without
considering of the uncertainties related to the uncertainty parameters.
However, RBTO involves evaluation of probabilistic constraints,
which can be done in two different ways, the reliability index
approach (RIA) and the performance measure approach (PMA). Limit
state function is approximated using Monte Carlo Simulation and
Central Composite Design for reliability analysis. ESO, one of the
topology optimization techniques, is adopted for topology
optimization. Numerical examples are presented to compare the DTO
with RBTO.