Abstract: The k-nearest neighbors (knn) is a simple but effective method of classification. In this paper we present an extended version of this technique for chemical compounds used in High Throughput Screening, where the distances of the nearest neighbors can be taken into account. Our algorithm uses kernel weight functions as guidance for the process of defining activity in screening data. Proposed kernel weight function aims to combine properties of graphical structure and molecule descriptors of screening compounds. We apply the modified knn method on several experimental data from biological screens. The experimental results confirm the effectiveness of the proposed method.
Abstract: Titanium nitride (TiN) has been synthesized using the
sheet plasma negative ion source (SPNIS). The parameters used for
its effective synthesis has been determined from previous
experiments and studies. In this study, further enhancement of the
deposition rate of TiN synthesis and advancement of the SPNIS
operation is presented. This is primarily achieved by the addition of
Sm-Co permanent magnets and a modification of the configuration in
the TiN deposition process. The magnetic enhancement is aimed at
optimizing the sputtering rate and the sputtering yield of the process.
The Sm-Co permanent magnets are placed below the Ti target for
better sputtering by argon. The Ti target is biased from –250V to –
350V and is sputtered by Ar plasma produced at discharge current of
2.5–4A and discharge potential of 60–90V. Steel substrates of
dimensions 20x20x0.5mm3 were prepared with N2:Ar volumetric
ratios of 1:3, 1:5 and 1:10. Ocular inspection of samples exhibit
bright gold color associated with TiN. XRD characterization
confirmed the effective TiN synthesis as all samples exhibit the (200)
and (311) peaks of TiN and the non-stoichiometric Ti2N (220) facet.
Cross-sectional SEM results showed increase in the TiN deposition
rate of up to 0.35μm/min. This doubles what was previously obtained
[1]. Scanning electron micrograph results give a comparative
morphological picture of the samples. Vickers hardness results gave
the largest hardness value of 21.094GPa.
Abstract: Because of importance of energy, optimization of
power generation systems is necessary. Gas turbine cycles are
suitable manner for fast power generation, but their efficiency is
partly low. In order to achieving higher efficiencies, some
propositions are preferred such as recovery of heat from exhaust
gases in a regenerator, utilization of intercooler in a multistage
compressor, steam injection to combustion chamber and etc.
However thermodynamic optimization of gas turbine cycle, even
with above components, is necessary. In this article multi-objective
genetic algorithms are employed for Pareto approach optimization of
Regenerative-Intercooling-Gas Turbine (RIGT) cycle. In the multiobjective
optimization a number of conflicting objective functions
are to be optimized simultaneously. The important objective
functions that have been considered for optimization are entropy
generation of RIGT cycle (Ns) derives using Exergy Analysis and
Gouy-Stodola theorem, thermal efficiency and the net output power
of RIGT Cycle. These objectives are usually conflicting with each
other. The design variables consist of thermodynamic parameters
such as compressor pressure ratio (Rp), excess air in combustion
(EA), turbine inlet temperature (TIT) and inlet air temperature (T0).
At the first stage single objective optimization has been investigated
and the method of Non-dominated Sorting Genetic Algorithm
(NSGA-II) has been used for multi-objective optimization.
Optimization procedures are performed for two and three objective
functions and the results are compared for RIGT Cycle. In order to
investigate the optimal thermodynamic behavior of two objectives,
different set, each including two objectives of output parameters, are
considered individually. For each set Pareto front are depicted. The
sets of selected decision variables based on this Pareto front, will
cause the best possible combination of corresponding objective
functions. There is no superiority for the points on the Pareto front
figure, but they are superior to any other point. In the case of three
objective optimization the results are given in tables.
Abstract: For complete support of Quality of Service, it is better that environment itself predicts resource requirements of a job by using special methods in the Grid computing. The exact and correct prediction causes exact matching of required resources with available resources. After the execution of each job, the used resources will be saved in the active database named "History". At first some of the attributes will be exploit from the main job and according to a defined similarity algorithm the most similar executed job will be exploited from "History" using statistic terms such as linear regression or average, resource requirements will be predicted. The new idea in this research is based on active database and centralized history maintenance. Implementation and testing of the proposed architecture results in accuracy percentage of 96.68% to predict CPU usage of jobs and 91.29% of memory usage and 89.80% of the band width usage.
Abstract: A two-dimensional moving mesh algorithm is developed to simulate the general motion of two rotating bodies with relative translational motion. The grid includes a background grid and two sets of grids around the moving bodies. With this grid arrangement rotational and translational motions of two bodies are handled separately, with no complications. Inter-grid boundaries are determined based on their distances from two bodies. In this method, the overset concept is applied to hybrid grid, and flow variables are interpolated using a simple stencil. To evaluate this moving mesh algorithm unsteady Euler flow is solved for different cases using dual-time method of Jameson. Numerical results show excellent agreement with experimental data and other numerical results. To demonstrate the capability of present algorithm for accurate solution of flow fields around moving bodies, some benchmark problems have been defined in this paper.
Abstract: This study was conducted to evaluate the antifungal
activities of Cinnamomum zeylanicum and Origanum vulgare L.
essential oil against Aspergillus flavus in culture media and tomato
paste. 200 ppm of cinnamon and 500 ppm of oregano completely
inhibited A. flavus growth in culture media, while in tomato paste 300
ppm of cinnamon and 200 ppm of oregano had the same effect. Test
panel evaluations revealed that samples with 100 and 200 ppm
cinnamon were acceptable. The results may suggest the potential use
of Cinnamomum zeylanicum essential oil as natural preservative in
tomato paste.
Abstract: A new voltage-mode triple-input single-output multifunction filter using only two current conveyors is presented. The proposed filter which possesses three inputs and single-output can generate all biquadratic filtering functions at the output terminal by selecting different input signal combinations. The validity of the proposed filter is verified through PSPICE simulations.
Abstract: This study examined the underlying dimensions of
brand equity in the chocolate industry. For this purpose, researchers
developed a model to identify which factors are influential in
building brand equity. The second purpose was to assess brand
loyalty and brand images mediating effect between brand attitude,
brand personality, brand association with brand equity. The study
employed structural equation modeling to investigate the causal
relationships between the dimensions of brand equity and brand
equity itself. It specifically measured the way in which consumers’
perceptions of the dimensions of brand equity affected the overall
brand equity evaluations. Data were collected from a sample of
consumers of chocolate industry in Iran. The results of this empirical
study indicate that brand loyalty and brand image are important
components of brand equity in this industry. Moreover, the role of
brand loyalty and brand image as mediating factors in the intention of
brand equity are supported. The principal contribution of the present
research is that it provides empirical evidence of the
multidimensionality of consumer based brand equity, supporting
Aaker´s and Keller´s conceptualization of brand equity. The present
research also enriched brand equity building by incorporating the
brand personality and brand image, as recommended by previous
researchers. Moreover, creating the brand equity index in chocolate
industry of Iran particularly is novel.
Abstract: This paper estimates the economic values of
household preference for enhanced solid waste disposal services in
Malaysia. The contingent valuation (CV) method estimates an
average additional monthly willingness-to-pay (WTP) in solid waste
management charges of Ôé¼0.77 to 0.80 for improved waste disposal
services quality. The finding of a slightly higher WTP from the
generic CV question than that of label-specific, further reveals a
higher WTP for sanitary landfill, at Ôé¼0.90, than incineration, at Ôé¼0.63.
This suggests that sanitary landfill is a more preferred alternative.
The logistic regression estimation procedure reveals that household-s
concern of where their rubbish is disposed, age, ownership of house,
household income and format of CV question are significant factors
in influencing WTP.
Abstract: The present study aims at determining the effect of ageing on the impact toughness and microstructure of 2024 Al-Cu - Mg alloy. Following the 2 h solutionizing treatment at 450°C and water quench, the specimens were aged at 200°C for various periods (1 to 18 h). The precipitation stages during ageing were monitored by hardness measurements. For each specimen group, Charpy impact and hardness tests were carried out. During ageing the impact toughness of the alloy first increased, and then, following a maxima decreased due to the precipitation of intermediate phases, finally it reached its minimum at the peak hardness. Correlations between hardness and impact toughness were investigated.
Abstract: Competitive relationships among Bradyrhizobium
japonicum USDA serogroup 123, 122 and 138 were screened versus
the standard commercial soybean variety Williams and two
introductions P1 377578 "671" in a field trial. Displacement of strain
123 by an effective strain should improved N2 fixation. Root nodules
were collected and strain occupancy percentage was determined
using strain specific fluorescent antibodies technique. As anticipated
the strain USDA 123 dominated 92% of nodules due to the high
affinity between the host and the symbiont. This dominance was
consistent and not changed materially either by inoculation practice
or by introducing new strainan. The interrelationship between the
genotype Williams and serogroup 122 & 138 was found very weak
although the cell density of the strain in the rhizosphere area was
equal. On the other hand, the nodule occupancy of genotypes 671 and
166 with rhizobia serogroup 123 was almost diminished to zero. .
The data further exhibited that the genotypes P1 671 and P1 166 have
high affinity to colonize with strains 122 and 138 whereas Williams
was highly promiscuous to strain 123.
Abstract: Phrases has a long history in information retrieval, particularly in commercial systems. Implicit semantic relationship between words in a form of BaseNP have shown significant improvement in term of precision in many IR studies. Our research focuses on linguistic phrases which is language dependent. Our results show that using BaseNP can improve performance although above 62% of words formation in Malay Language based on derivational affixes and suffixes.
Abstract: The purpose of the present study is the investigation
of the relationship between knowledge management and enabling
managers based on achieving proper function. This research is
descriptive and investigative. The sample includes all male and
female high school managers of first and second regions of Urmia
including 98 school and accordingly 98 managers. The instrument
applied was a questionnaire. To sum up, there is a statistically
significant relationship between knowledge management and
empowering managers. In the end, several suggestions are provided.
Abstract: In the present work we investigate both the elastic and
electric properties of a chiral material. We consider a composite
structure made from a polymer matrix and anisotropic inclusions of
GaAs taking into account piezoelectric and dielectric properties of
the composite material. The principal task of the work is the
estimation of the functional properties of the composite material.
Abstract: Stair climbing is one of critical issues for field robots to
widen applicable areas. This paper presents optimal design on
kinematic parameters of a new robotic platform for stair climbing. The
robotic platform climbs various stairs by body flip locomotion with
caterpillar type main platform. Kinematic parameters such as platform
length, platform height, and caterpillar rotation speed are optimized to
maximize stair climbing stability. Three types of stairs are used to
simulate typical user conditions. The optimal design process is
conducted based on Taguchi methodology, and resulting parameters
with optimized objective function are presented. In near future, a
prototype is assembled for real environment testing.
Abstract: In this paper is shown that the probability-statistic methods application, especially at the early stage of the aviation gas turbine engine (GTE) technical condition diagnosing, when the flight information has property of the fuzzy, limitation and uncertainty is unfounded. Hence is considered the efficiency of application of new technology Soft Computing at these diagnosing stages with the using of the Fuzzy Logic and Neural Networks methods. Training with high accuracy of fuzzy multiple linear and non-linear models (fuzzy regression equations) which received on the statistical fuzzy data basis is made. Thus for GTE technical condition more adequate model making are analysed dynamics of skewness and kurtosis coefficients' changes. Researches of skewness and kurtosis coefficients values- changes show that, distributions of GTE work parameters have fuzzy character. Hence consideration of fuzzy skewness and kurtosis coefficients is expedient. Investigation of the basic characteristics changes- dynamics of GTE work parameters allows to draw conclusion on necessity of the Fuzzy Statistical Analysis at preliminary identification of the engines' technical condition. Researches of correlation coefficients values- changes shows also on their fuzzy character. Therefore for models choice the application of the Fuzzy Correlation Analysis results is offered. For checking of models adequacy is considered the Fuzzy Multiple Correlation Coefficient of Fuzzy Multiple Regression. At the information sufficiency is offered to use recurrent algorithm of aviation GTE technical condition identification (Hard Computing technology is used) on measurements of input and output parameters of the multiple linear and non-linear generalised models at presence of noise measured (the new recursive Least Squares Method (LSM)). The developed GTE condition monitoring system provides stage-bystage estimation of engine technical conditions. As application of the given technique the estimation of the new operating aviation engine temperature condition was made.
Abstract: Web applications have become complex and crucial for many firms, especially when combined with areas such as CRM (Customer Relationship Management) and BPR (Business Process Reengineering). The scientific community has focused attention to Web application design, development, analysis, testing, by studying and proposing methodologies and tools. Static and dynamic techniques may be used to analyze existing Web applications. The use of traditional static source code analysis may be very difficult, for the presence of dynamically generated code, and for the multi-language nature of the Web. Dynamic analysis may be useful, but it has an intrinsic limitation, the low number of program executions used to extract information. Our reverse engineering analysis, used into our WAAT (Web Applications Analysis and Testing) project, applies mutational techniques in order to exploit server side execution engines to accomplish part of the dynamic analysis. This paper studies the effects of mutation source code analysis applied to Web software to build application models. Mutation-based generated models may contain more information then necessary, so we need a pruning mechanism.
Abstract: This paper presents a critical study about the
application of Neural Networks to ion-exchange process. Ionexchange
is a complex non-linear process involving many factors
influencing the ions uptake mechanisms from the pregnant solution.
The following step includes the elution. Published data presents
empirical isotherm equations with definite shortcomings resulting in
unreliable predictions. Although Neural Network simulation
technique encounters a number of disadvantages including its “black
box", and a limited ability to explicitly identify possible causal
relationships, it has the advantage to implicitly handle complex
nonlinear relationships between dependent and independent
variables. In the present paper, the Neural Network model based on
the back-propagation algorithm Levenberg-Marquardt was developed
using a three layer approach with a tangent sigmoid transfer function
(tansig) at hidden layer with 11 neurons and linear transfer function
(purelin) at out layer. The above mentioned approach has been used
to test the effectiveness in simulating ion exchange processes. The
modeling results showed that there is an excellent agreement between
the experimental data and the predicted values of copper ions
removed from aqueous solutions.
Abstract: This study aims to screen out and to optimize the
major nutrients for maximum carotenoid production and
antioxidation characteristics by Rhodotorula rubra. It was found that
supplementary of 10 g/l glucose as carbon source, 1 g/l ammonium
sulfate as nitrogen source and 1 g/l yeast extract as growth factor in
the medium provided the better yield of carotenoid content of 30.39
μg/g cell dry weight the amount of antioxidation of Rhodotorula
rubra by DPPH, ABTS and MDA method were 1.463%, 34.21% and
34.09 μmol/l, respectively.
Abstract: Environmental awareness and the recent
environmental policies have forced many electric utilities to
restructure their operational practices to account for their emission
impacts. One way to accomplish this is by reformulating the
traditional economic dispatch problem such that emission effects are
included in the mathematical model. This paper presents a Particle
Swarm Optimization (PSO) algorithm to solve the Economic-
Emission Dispatch problem (EED) which gained recent attention due
to the deregulation of the power industry and strict environmental
regulations. The problem is formulated as a multi-objective one with
two competing functions, namely economic cost and emission
functions, subject to different constraints. The inequality constraints
considered are the generating unit capacity limits while the equality
constraint is generation-demand balance. A novel equality constraint
handling mechanism is proposed in this paper. PSO algorithm is
tested on a 30-bus standard test system. Results obtained show that
PSO algorithm has a great potential in handling multi-objective
optimization problems and is capable of capturing Pareto optimal
solution set under different loading conditions.