Abstract: Lateral Geniculate Nucleus (LGN) is the relay center
in the visual pathway as it receives most of the input information
from retinal ganglion cells (RGC) and sends to visual cortex. Low
threshold calcium currents (IT) at the membrane are the unique
indicator to characterize this firing functionality of the LGN neurons
gained by the RGC input. According to the LGN functional
requirements such as functional mapping of RGC to LGN, the
morphologies of the LGN neurons were developed. During the
neurological disorders like glaucoma, the mapping between RGC and
LGN is disconnected and hence stimulating LGN electrically using
deep brain electrodes can restore the functionalities of LGN. A
computational model was developed for simulating the LGN neurons
with three predominant morphologies each representing different
functional mapping of RGC to LGN. The firings of action potentials
at LGN neuron due to IT were characterized by varying the
stimulation parameters, morphological parameters and orientation. A
wide range of stimulation parameters (stimulus amplitude, duration
and frequency) represents the various strengths of the electrical
stimulation with different morphological parameters (soma size,
dendrites size and structure). The orientation (0-1800) of LGN
neuron with respect to the stimulating electrode represents the angle
at which the extracellular deep brain stimulation towards LGN
neuron is performed. A reduced dendrite structure was used in the
model using Bush–Sejnowski algorithm to decrease the
computational time while conserving its input resistance and total
surface area. The major finding is that an input potential of 0.4 V is
required to produce the action potential in the LGN neuron which is
placed at 100 μm distance from the electrode. From this study, it can
be concluded that the neuroprostheses under design would need to
consider the capability of inducing at least 0.4V to produce action
potentials in LGN.
Abstract: To explore how the brain may recognise objects in its
general,accurate and energy-efficient manner, this paper proposes the
use of a neuromorphic hardware system formed from a Dynamic
Video Sensor (DVS) silicon retina in concert with the SpiNNaker
real-time Spiking Neural Network (SNN) simulator. As a first step
in the exploration on this platform a recognition system for dynamic
hand postures is developed, enabling the study of the methods used
in the visual pathways of the brain. Inspired by the behaviours of
the primary visual cortex, Convolutional Neural Networks (CNNs)
are modelled using both linear perceptrons and spiking Leaky
Integrate-and-Fire (LIF) neurons.
In this study’s largest configuration using these approaches, a
network of 74,210 neurons and 15,216,512 synapses is created and
operated in real-time using 290 SpiNNaker processor cores in parallel
and with 93.0% accuracy. A smaller network using only 1/10th of the
resources is also created, again operating in real-time, and it is able
to recognise the postures with an accuracy of around 86.4% - only
6.6% lower than the much larger system. The recognition rate of the
smaller network developed on this neuromorphic system is sufficient
for a successful hand posture recognition system, and demonstrates
a much improved cost to performance trade-off in its approach.
Abstract: Fabric textures are very common in our daily life.
However, the representation of fabric textures has never been explored
from neuroscience view. Theoretical studies suggest that primary
visual cortex (V1) uses a sparse code to efficiently represent natural
images. However, how the simple cells in V1 encode the artificial
textures is still a mystery. So, here we will take fabric texture as
stimulus to study the response of independent component analysis that
is established to model the receptive field of simple cells in V1. We
choose 140 types of fabrics to get the classical fabric textures as
materials. Experiment results indicate that the receptive fields of
simple cells have obvious selectivity in orientation, frequency and
phase when drifting gratings are used to determine their tuning
properties. Additionally, the distribution of optimal orientation and
frequency shows that the patch size selected from each original fabric
image has a significant effect on the frequency selectivity.
Abstract: Functional Magnetic Resonance Imaging(fMRI) is a
noninvasive imaging technique that measures the hemodynamic
response related to neural activity in the human brain. Event-related
functional magnetic resonance imaging (efMRI) is a form of
functional Magnetic Resonance Imaging (fMRI) in which a series of
fMRI images are time-locked to a stimulus presentation and averaged
together over many trials. Again an event related potential (ERP) is a
measured brain response that is directly the result of a thought or
perception. Here the neuronal response of human visual cortex in
normal healthy patients have been studied. The patients were asked
to perform a visual three choice reaction task; from the relative
response of each patient corresponding neuronal activity in visual
cortex was imaged. The average number of neurons in the adult
human primary visual cortex, in each hemisphere has been estimated
at around 140 million. Statistical analysis of this experiment was
done with SPM5(Statistical Parametric Mapping version 5) software.
The result shows a robust design of imaging the neuronal activity of
human visual cortex.