Abstract: Human amniotic membrane (HAM) is a useful
biological material for the reconstruction of damaged ocular surface.
The processing and preservation of HAM is critical to prevent the
patients undergoing amniotic membrane transplant (AMT) from cross
infections. For HAM preparation human placenta is obtained after an
elective cesarean delivery. Before collection, the donor is screened
for seronegativity of HCV, Hbs Ag, HIV and Syphilis. After
collection, placenta is washed in balanced salt solution (BSS) in
sterile environment. Amniotic membrane is then separated from the
placenta as well as chorion while keeping the preparation in BSS.
Scrapping of HAM is then carried out manually until all the debris is
removed and clear transparent membrane is acquired. Nitrocellulose
membrane filters are then placed on the stromal side of HAM, cut
around the edges with little membrane folded towards other side
making it easy to separate during surgery. HAM is finally stored in
solution of glycerine and Dulbecco-s Modified Eagle Medium
(DMEM) in 1:1 ratio containing antibiotics. The capped borosil vials
containing HAM are kept at -80°C until use. This vial is thawed to
room temperature and opened under sterile operation theatre
conditions at the time of surgery.
Abstract: Interactive web-based computer simulations are
needed by the medical community to replicate the experience of
surgical procedures as closely and realistically as possible without
the need to practice on corpses, animals and/or plastic models. In this
paper, we offer a review on current state of the research on
simulations of surgical threads, identify future needs and present our
proposed plans to meet them. Our goal is to create a physics-based
simulator, which will predict the behavior of surgical thread when
subjected to conditions commonly encountered during surgery. To
that end, we will i) develop three dimensional finite element models
based on the Cosserat theory of elasticity ii) test and feedback results
with the medical community and iii) develop a web-based user
interface to run/command our simulator and visualize the results. The
impacts of our research are that i) it will contribute to the
development of a new generation of training for medical school
students and ii) the simulator will be useful to expert surgeons in
developing new, better and less risky procedures.
Abstract: This paper presents design and characterization of a
microaccelerometer designated for integration into cataract surgical
probe to detect hardness of different eye tissues during cataract
surgery. Soft posterior lens capsule of eye can be easily damaged in
comparison with hard opaque lens since the surgeon can not see
directly behind cutting needle during the surgery. Presence of
microsensor helps the surgeon to avoid rupturing posterior lens
capsule which if occurs leads to severe complications such as
glaucoma, infection, or even blindness. The microsensor having
overall dimensions of 480 μm x 395 μm is able to deliver significant
capacitance variations during encountered vibration situations which
makes it capable to distinguish between different types of tissue.
Integration of electronic components on chip ensures high level of
reliability and noise immunity while minimizes space and power
requirements. Physical characteristics and results on performance
testing, proves integration of microsensor as an effective tool to aid
the surgeon during this procedure.
Abstract: A new and cost effective robotic device was designed
for remote tele surgery using dual tone multi frequency technology
(DTMF). Tele system with Dual Tone Multiple Frequency has a large
capability in sending and receiving of data in hardware and software.
The robot consists of DC motors for arm movements and it is
controlled manually through a mobile phone through DTMF
Technology. The system enables the surgeon from base station to
send commands through mobile phone to the patient’s robotic system
which includes two robotic arms that translate the input into actual
instrument manipulation. A mobile phone attached to the
microcontroller 8051 which can activate robot through relays. The
Remote robot-assisted tele surgery eliminates geographic constraints
for getting surgical expertise where it is needed and allows an expert
surgeon to teach or proctor the performance of surgical technique by
real-time intervention.
Abstract: Magnesium is used implant material potentially for
non-toxicity to the human body. Due to the excellent
bio-compatibility, Mg alloys is applied to implants avoiding removal
second surgery. However, it is found commercial magnesium alloys
including aluminum has low corrosion resistance, resulting
subcutaneous gas bubbles and consequently the approach as
permanent bio-materials. Generally, Aluminum is known to pollution
substance, and it raises toxicity to nervous system. Therefore
especially Mg-35Zn-3Ca alloy is prepared for new biodegradable
materials in this study. And the pulsed power is used in
constant-current mode of DC power kinds of anodization. Based on
the aforementioned study, it examines corrosion resistance and
biocompatibility by effect of current and frequency variation. The
surface properties and thickness were compared using scanning
electronic microscopy. Corrosion resistance was assessed via
potentiodynamic polarization and the effect of oxide layer on the body
was assessed cell viability. Anodized Mg-35Zn-3Ca alloy has good
biocompatibility in vitro by current and frequency variation.
Abstract: Deaths from cardiovascular diseases have decreased substantially over the past two decades, largely as a result of advances in acute care and cardiac surgery. These developments have produced a growing population of patients who have survived a myocardial infarction. These patients need to be continuously monitored so that the initiation of treatment can be given within the crucial golden hour. The available conventional methods of monitoring mostly perform offline analysis and restrict the mobility of these patients within a hospital or room. Hence the aim of this paper is to design a Portable Cardiac Telemedicine System to aid the patients to regain their independence and return to an active work schedule, there by improving the psychological well being. The portable telemedicine system consists of a Wearable ECG Transmitter (WET) and a slightly modified mobile phone, which has an inbuilt ECG analyzer. The WET is placed on the body of the patient that continuously acquires the ECG signals from the high-risk cardiac patients who can move around anywhere. This WET transmits the ECG to the patient-s Bluetooth enabled mobile phone using blue tooth technology. The ECG analyzer inbuilt in the mobile phone continuously analyzes the heartbeats derived from the received ECG signals. In case of any panic condition, the mobile phone alerts the patients care taker by an SMS and initiates the transmission of a sample ECG signal to the doctor, via the mobile network.
Abstract: In the present study, changes of morphology and
mechanical characteristics in the lumbar vertebrae of the
ovariectomised (OVX) rat were investigated. In previous researches,
there were many studies about morphology like volume fraction and
trabecular thickness based on Micro - Computed Tomography (Micro
- CT). However, detecting and tracking long-term changes in the
trabecular bone of the lumbar vertebrae for the OVX rat were few. For
this study, one female Sprague-Dawley rat was used: an OVX rat. The
4th Lumbar of the OVX rat was subjected to in-vivo micro-CT.
Detecting and tracking long-term changes could be investigated in the
trabecular bone of the lumbar vertebrae for an OVX rat using in-vivo
micro-CT. An OVX rat was scanned at week 0 (just before surgery), at
week 4, at week 8, week 16, week 22 and week 56 after surgery. Finite
element (FE) analysis was used to investigate mechanical
characteristics of the lumbar vertebrae for an OVX rat. When the OVX
rat (at week 56) was compared with the OVX rat (at week 0), volume
fraction was decreased by 80% and effective modulus was decreased
by 75%.
Abstract: The use of machine vision to inspect the outcome of
surgical tasks is investigated, with the aim of incorporating this
approach in robotic surgery systems. Machine vision is a non-contact
form of inspection i.e. no part of the vision system is in direct contact
with the patient, and is therefore well suited for surgery where
sterility is an important consideration,. As a proof-of-concept, three
primary surgical tasks for a common neurosurgical procedure were
inspected using machine vision. Experiments were performed on
cadaveric pig heads to simulate the two possible outcomes i.e.
satisfactory or unsatisfactory, for tasks involved in making a burr
hole, namely incision, retraction, and drilling. We identify low level
image features to distinguish the two outcomes, as well as report on
results that validate our proposed approach. The potential of using
machine vision in a surgical environment, and the challenges that
must be addressed, are identified and discussed.
Abstract: This paper presents the design of a ring-shaped tri-axial fore sensor that can be incorporated into the tip of a guidewire for use in minimally invasive surgery (MIS). The designed sensor comprises a ring-shaped structure located at the center of four cantilever beams. The ringdesign allows surgical tools to be easily passed through which largely simplified the integration process. Silicon nanowires (SiNWs) are used aspiezoresistive sensing elementsembeddedon the four cantilevers of the sensor to detect the resistance change caused by the applied load.An integration scheme with new designed guidewire tip structure having two coils at the distal end is presented. Finite element modeling has been employed in the sensor design to find the maximum stress location in order to put the SiNWs at the high stress regions to obtain maximum output. A maximum applicable force of 5 mN is found from modeling. The interaction mechanism between the designed sensor and a steel wire has been modeled by FEM. A linear relationship between the applied load on the steel wire and the induced stress on the SiNWs were observed.
Abstract: Sensorized instruments that accurately measure the interaction forces (between biological tissue and instrument endeffector) during surgical procedures offer surgeons a greater sense of immersion during minimally invasive robotic surgery. Although there is ongoing research into force measurement involving surgical graspers little corresponding effort has been carried out on the measurement of forces between scissor blades and tissue. This paper presents the design and development of a force measurement test apparatus, which will serve as a sensor characterization and evaluation platform. The primary aim of the experiments is to ascertain whether the system can differentiate between tissue samples with differing mechanical properties in a reliable, repeatable manner. Force-angular displacement curves highlight trends in the cutting process as well the forces generated along the blade during a cutting procedure. Future applications of the test equipment will involve the assessment of new direct force sensing technologies for telerobotic surgery.