Abstract: The progress of concentrations of particular heavy metals was assessed in chosen localities in region Moravia, the Czech Republic, from 2007 to 2009. Particular metals were observed in localities with various types and characterization of zone. Pb, Ni, As and Cd were emphasized as a result of their toxicity and potential adverse health effect to the exposed population. The progress of metal concentrations and their health effects in the most polluted localities were examined. According to the results, the air pollution limit values were not exceeded. Based on the health risk assessment, the probability of developing tumorous diseases is acceptable, except for the increased probability of cancer risk from long-term exposure to As.
Abstract: To estimate the risks of dam failure phenomenon, it is necessary to understand this phenomenon and the involved governing factors. Overtopping and piping are the two main reasons of earthdam failures. In the piping context, the piping is determined as a phenomenon which is occurred between two phases, the water liquid and the solid soil. In this investigation, the onset of piping and its development, as well as the movement of water in soil, are numerically approached. In this regard, a one-dimensional numerical model based on the mass-conserving finite-volume method is developed and applied in order to simulate the piping phenomenon in a continuous circular tunnel of given initial length and radius, located between upstream and downstream. The simulation result includes the time-variations of radius along the tunnel until the radius value reaches its critical and the piping phenomenon converts to overtopping.
Abstract:
Innovation is becoming more and more important in
modern society. There are a lot of researches on different kinds of
innovation but marketing innovation is one kind of innovation that
has not been studied frequently before. Marketing innovation is
defined as a new way in which companies can market themselves to
potential or existing customers.
The study shows some key elements for marketing innovation that
are worth paying attention to when implementing marketing
innovation projects. Examples of such key elements are: paying
attention to the neglected market, suitable market segmentatio
reliable market information, public relationship, increased customer
value, combination of market factors, explore different marketing
channels and the use of technology in combination with what? Beside
the key elements for marketing innovation, we also present some
risks that may occur, such as cost, market uncertainty, information
leakage, imitation and overdependence on experience.
By proposing a set of indicators to measure marketing innovation,
the article offers solutions for marketing innovation implementation
so that any organization can achieve optimal results.
Abstract: In recent years, copulas have become very popular in
financial research and actuarial science as they are more flexible in
modelling the co-movements and relationships of risk factors as compared
to the conventional linear correlation coefficient by Pearson.
However, a precise estimation of the copula parameters is vital in
order to correctly capture the (possibly nonlinear) dependence structure
and joint tail events. In this study, we employ two optimization
heuristics, namely Differential Evolution and Threshold Accepting to
tackle the parameter estimation of multivariate t distribution models
in the EML approach. Since the evolutionary optimizer does not rely
on gradient search, the EML approach can be applied to estimation of
more complicated copula models such as high-dimensional copulas.
Our experimental study shows that the proposed method provides
more robust and more accurate estimates as compared to the IFM
approach.
Abstract: Hazardous Material transportation by road is coupled
with inherent risk of accidents causing loss of lives, grievous injuries,
property losses and environmental damages. The most common type
of hazmat road accident happens to be the releases (78%) of
hazardous substances, followed by fires (28%), explosions (14%) and
vapour/ gas clouds (6 %.).
The paper is discussing initially the probable 'Impact Zones'
likely to be caused by one flammable (LPG) and one toxic (ethylene
oxide) chemicals being transported through a sizable segment of a
State Highway connecting three notified Industrial zones in Surat
district in Western India housing 26 MAH industrial units. Three
'hotspots' were identified along the highway segment depending on
the particular chemical traffic and the population distribution within
500 meters on either sides. The thermal radiation and explosion
overpressure have been calculated for LPG / Ethylene Oxide BLEVE
scenarios along with toxic release scenario for ethylene oxide.
Besides, the dispersion calculations for ethylene oxide toxic release
have been made for each 'hotspot' location and the impact zones
have been mapped for the LOC concentrations. Subsequently, the
maximum Initial Isolation and the protective zones were calculated
based on ERPG-3 and ERPG-2 values of ethylene oxide respectively
which are estimated taking the worst case scenario under worst
weather conditions. The data analysis will be helpful to the local
administration in capacity building with respect to rescue /
evacuation and medical preparedness and quantitative inputs to
augment the District Offsite Emergency Plan document.
Abstract: Support Vector Machine (SVM) is a statistical learning tool that was initially developed by Vapnik in 1979 and later developed to a more complex concept of structural risk minimization (SRM). SVM is playing an increasing role in applications to detection problems in various engineering problems, notably in statistical signal processing, pattern recognition, image analysis, and communication systems. In this paper, SVM was applied to the detection of medical ultrasound images in the presence of partially developed speckle noise. The simulation was done for single look and multi-look speckle models to give a complete overlook and insight to the new proposed model of the SVM-based detector. The structure of the SVM was derived and applied to clinical ultrasound images and its performance in terms of the mean square error (MSE) metric was calculated. We showed that the SVM-detected ultrasound images have a very low MSE and are of good quality. The quality of the processed speckled images improved for the multi-look model. Furthermore, the contrast of the SVM detected images was higher than that of the original non-noisy images, indicating that the SVM approach increased the distance between the pixel reflectivity levels (detection hypotheses) in the original images.
Abstract: Gas hydrates can agglomerate and block multiphase oil and gas pipelines when water is present at hydrate forming conditions. Using "Cold Flow Technology", the aim is to condition gas hydrates so that they can be transported as a slurry mixture without a risk of agglomeration. During the pipeline shut down however, hydrate particles may settle in bends and build hydrate plugs. An experimental setup has been designed and constructed to study the flow of such plugs at start up operations. Experiments have been performed using model fluid and model hydrate particles. The propagations of initial plugs in a bend were recorded with impedance probes along the pipe. The experimental results show a dispersion of the plug front. A peak in pressure drop was also recorded when the plugs were passing the bend. The evolutions of the plugs have been simulated by numerical integration of the incompressible mass balance equations, with an imposed mixture velocity. The slip between particles and carrier fluid has been calculated using a drag relation together with a particle-fluid force balance.
Abstract: Construction of tunnels is connected with high
uncertainty in the field of costs, construction period, safety and
impact on surroundings. Risk management became therefore a
common part of tunnel projects, especially after a set of fatal
collapses occurred in 1990's. Such collapses are caused usually by
combination of factors that can be divided into three main groups, i.e.
unfavourable geological conditions, failures in the design and
planning or failures in the execution.
This paper suggests a procedure enabling quantification of the
excavation risk related to extraordinary accidents using FTA and
ETA tools. It will elaborate on a common process of risk analysis and
enable the transfer of information and experience between particular
tunnel construction projects. Further, it gives a guide for designers,
management and other participants, how to deal with risk of such
accidents and how to make qualified decisions based on a
probabilistic approach.
Abstract: Commercial nanocomposite food packaging type nano-silver containers were characterised using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX). The presence of nanoparticles consistent with the incorporation of 1% nano-silver (Ag) and 0.1% titanium dioxide (TiO2) nanoparticle into polymeric materials formed into food containers was confirmed. Both nanomaterials used in this type of packaging appear to be embedded in a layered configuration within the bulk polymer. The dimensions of the incorporated nanoparticles were investigated using X-ray diffraction (XRD) and determined by calculation using the Scherrer Formula; these were consistent with Ag and TiO2 nanoparticles in the size range 20-70nm both were spherical shape nanoparticles. Antimicrobial assessment of the nanocomposite container has also been performed and the results confirm the antimicrobial activity of Ag and TiO2 nanoparticles in food packaging containers. Migration assessments were performed in a wide range of food matrices to determine the migration of nanoparticles from the packages. The analysis was based upon the relevant European safety Directives and involved the application of inductively coupled plasma mass spectrometry (ICP-MS) to identify the range of migration risk. The data pertain to insignificance levels of migration of Ag and TiO2 nanoparticles into the selected food matrices.
Abstract: Planning community has been long discussing emerging paradigms within the planning theory in the face of the changing conditions of the world order. The paradigm shift concept was introduced by Thomas Kuhn, in 1960, who claimed the necessity of shifting within scientific knowledge boundaries; and following him in 1970 Imre Loktas also gave priority to the emergence of multi-paradigm societies [24]. Multi-paradigm is changing our predetermined lifeworld through uncertainties. Those uncertainties are reflected in two sides, the first one is uncertainty as a concept of possibility and creativity in public sphere and the second one is uncertainty as a risk. Therefore, it is necessary to apply a resilience planning approach to be more dynamic in controlling uncertainties which have the potential to transfigure present time and space definitions. In this way, stability of system can be achieved. Uncertainty is not only an outcome of worldwide changes but also a place-specific issue, i.e. it changes from continent to continent, a country to country; a region to region. Therefore, applying strategic spatial planning with respect to resilience principle contributes to: control, grasp and internalize uncertainties through place-specific strategies. In today-s fast changing world, planning system should follow strategic spatial projects to control multi-paradigm societies with adaptability capacities. Here, we have selected two alternatives to demonstrate; these are; 1.Tehran (Iran) from the Middle East 2.Bath (United Kingdom) from Europe. The study elaborates uncertainties and particularities in their strategic spatial planning processes in a comparative manner. Through the comparison, the study aims at assessing place-specific priorities in strategic planning. The approach is to a two-way stream, where the case cities from the extreme end of the spectrum can learn from each other. The structure of this paper is to firstly compare semi-periphery (Tehran) and coreperiphery (Bath) cities, with the focus to reveal how they equip to face with uncertainties according to their geographical locations and local particularities. Secondly, the key message to address is “Each locality requires its own strategic planning approach to be resilient.--
Abstract: A 7-step method (with 25 sub-steps) to assess risk of
air pollutants is introduced. These steps are: pre-considerations,
sampling, statistical analysis, exposure matrix and likelihood, doseresponse
matrix and likelihood, total risk evaluation, and discussion
of findings. All mentioned words and expressions are wellunderstood;
however, almost all steps have been modified, improved,
and coupled in such a way that a comprehensive method has been
prepared. Accordingly, the SADRA (Statistical Analysis-Driven Risk
Assessment) emphasizes extensive and ongoing application of
analytical statistics in traditional risk assessment models. A Sulfur
Dioxide case study validates the claim and provides a good
illustration for this method.
Abstract: Safety of bus journey is a fundamental concern. Risk of injuries and fatalities is severe when bus superstructure fails during rollover accident. Adequate design and sufficient strength of bus superstructure can reduce the number of injuries and fatalities. This paper deals with structural analysis of bus superstructure undergoes rollover event. Several value of mass will be varied in multiple simulations. The purpose of this work is to analyze structural response of bus superstructure in terms of deformation, stress and strain under several loading and constraining conditions. A complete bus superstructure with forty four passenger-s capability was developed using finite element analysis software. Simulations have been conducted to observe the effect of total mass of bus on the strength of superstructure. These simulations are following United Nation Economic Commission of Europe regulation 66 which focuses on strength of large vehicle superstructure. Validation process had been done using simple box model experiment and results obtained are comparing with simulation results. Inputs data from validation process had been used in full scale simulation. Analyses suggested that, the failure of bus superstructure during rollover situation is basically dependent on the total mass of bus and on the strength of bus superstructure.
Abstract: It is believed that DNA damaging toxic metabolites contributes to the development of different pathological conditions. To prevent harmful influence of toxic agents, cells developed number of protecting mechanisms, such as enzymatic reaction of detoxification of reactive metabolites and repair of DNA damage. The aim of the study was to examine the association between polymorphism of GSTT1/GSTM1 and XRCC1/3 genes and coronary artery disease (CAD) incidence. To examine a polymorphism of these genes in CAD susceptibility in patients and controls, PCR based genotyping assay was performed. For GST genes, frequency of GSTM1 null genotype among CAD affected group was significantly increased than in control group (P0.1). We found that neither XRCC1 Arg399Gln nor XRCC3 Thr241Met were associated with CAD risk. Obtained data suggests that GSTM1 null genotype carriers are more susceptible to CAD development.
Abstract: Housebuilders in England have been the target of numerous government policies in recent years promoting increased productivity and affordability. As a result, the housebuilding industry is currently faced with objectives to improve the affordability and sustainability of new homes whilst also increasing production rates to 240,000 per year by 2016.Yet amidst a faltering economic climate, the UK Government is forging ahead with the 'Code for Sustainable Homes', which includes stringent sustainable standards for all new homes and sets ambitious targets for the housebuilding industry, the culmination of which is the production of zero carbon homes by 2016.Great uncertainty exists amongst housebuilders as to the costs, benefits and risks of building zero carbon homes. This paper examines the key barriers to zero carbon homes from housebuilders- perspective. A comprehensive opinion on the challenges to deliver zero carbon homes is gathered through a questionnaire survey issued to the major housing developers in England. The study found that a number of cultural, legislative, and financial barriers stand in the way of the widespread construction of zero carbon homes. The study concludes with several recommendations to both the Government and the housebuilding industry to address the barriers that hinder a successful delivery of zero carbon homes in England.
Abstract: While the form of crises may change, their essence
remains the same (such as a cycle of abundant liquidity, rapid credit
growth, and a low-inflation environment followed by an asset-price
bubble). The current market turbulence began in mid-2000s when the
US economy shifted to imbalanced both internal and external
macroeconomic positions. We see two key causes of these problems
– loose US monetary policy in early 2000s and US government
guarantees issued on the securities by government-sponsored
enterprises what was further fueled by financial innovations such as
structured credit products. We have discovered both negative and
positive lessons deriving from this crisis and divided the negative
lessons into three groups: financial products and valuation, processes
and business models, and strategic issues. Moreover, we address key
risk management lessons and exit strategies derived from the current
crisis and recommend policies that should help diminish the negative
impact of future potential crises.
Abstract: Reducing the risk of information leaks is one of
the most important functions of identity management systems. To
achieve this purpose, Dey et al. have already proposed an account
management method for a federated login system using a blind
signature scheme. In order to ensure account anonymity for the
authentication provider, referred to as an IDP (identity provider),
a blind signature scheme is utilized to generate an authentication
token on an authentication service and the token is sent to an IDP.
However, there is a problem with the proposed system. Malicious
users can establish multiple accounts on an IDP by requesting such
accounts. As a measure to solve this problem, in this paper, the
authors propose an account checking method that is performed before
account generation.
Abstract: The p53 tumor suppressor gene plays two important
roles in genomic stability: blocking cell proliferation after DNA
damage until it has been repaired, and starting apoptosis if the
damage is too critical. Codon 72 exon4 polymorphism (Arg72Pro) of
the P53 gene has been implicated in cancer risk. Various studies have
been done to investigate the status of p53 at codon 72 for arginine
(Arg) and proline (Pro) alleles in different populations and also the
association of this codon 72 polymorphism with various tumors. Our
objective was to investigate the possible association between P53
Arg72Pro polymorphism and susceptibility to colorectal cancer
among Isfahan and Chaharmahal Va Bakhtiari (a part of south west
of Iran) population. We investigated the status of p53 at codon 72 for
Arg/Arg, Arg/Pro and Pro/Pro allele polymorphisms in blood
samples from 145 colorectal cancer patients and 140 controls by
Nested-PCR of p53 exon 4 and digestion with BstUI restriction
enzyme and the DNA fragments were then resolved by
electrophoresis in 2% agarose gel. The Pro allele was 279 bp, while
the Arg allele was restricted into two fragments of 160 and 119 bp.
Among the 145 colorectal cancer cases 49 cases (33.79%) were
homozygous for the Arg72 allele (Arg/Arg), 18 cases (12.41%) were
homozygous for the Pro72 allele (Pro/Pro) and 78 cases (53.8%)
found in heterozygous (Arg/Pro).
In conclusion, it can be said that p53Arg/Arg genotype may be
correlated with possible increased risk of this kind of cancers in south
west of Iran.
Abstract: The contamination of 15 ground water resources
of a selected region earmarked for the emergency supply
of population has been monitored. The resources have been selected
on the basis of previous assessment of natural conditions
and the exploitation of territory in their surroundings and infiltration
area. Two resources out of 15 have been excluded from further
exploitation, because they have not met some of the 72 assessed
hygienic indicators of extended analysis. The remaining 13 resources
have been the subject of health risk analysis in relation
to the contamination by arsenic, lead, cadmium, mercury, nickel and
manganese. The risk analysis proved that all 13 resources meet
health standards with regard to the above mentioned purposefully
selected elements and may thus be included into crisis plans. Water
quality of ground resources may be assessed in the same way
with regard to other contaminants.
Abstract: This study proposes a materials procurement contracts
model to which the zero-cost collar option is applied for heading price
fluctuation risks in construction.The material contract model based on
the collar option that consists of the call option striking zone of the
construction company(the buyer) following the materials price
increase andthe put option striking zone of the material vendor(the
supplier) following a materials price decrease. This study first
determined the call option strike price Xc of the construction company
by a simple approach: it uses the predicted profit at the project starting
point and then determines the strike price of put option Xp that has an
identical option value, which completes the zero-cost material
contract.The analysis results indicate that the cost saving of the
construction company increased as Xc decreased. This was because the
critical level of the steel materials price increasewas set at a low level.
However, as Xc decreased, Xpof a put option that had an identical
option value gradually increased. Cost saving increased as Xc
decreased. However, as Xp gradually increased, the risk of loss from a
construction company increased as the steel materials price decreased.
Meanwhile, cost saving did not occur for the construction company,
because of volatility. This result originated in the zero-cost features of
the two-way contract of the collar option. In the case of the regular
one-way option, the transaction cost had to be subtracted from the cost
saving. The transaction cost originated from an option value that
fluctuated with the volatility. That is, the cost saving of the one-way
option was affected by the volatility. Meanwhile, even though the
collar option with zero transaction cost cut the connection between
volatility and cost saving, there was a risk of exercising the put option.
Abstract: In this paper, we propose a hardware and software
design method for automotive Electronic Control Units (ECU)
considering the functional safety. The proposed ECU is considered for
the application to Electro-Mechanical Actuator systems and the
validity of the design method is shown by the application to the
Electro-Mechanical Brake (EMB) control system which is used as a
brake actuator in Brake-By-Wire (BBW) systems. The importance of a
functional safety-based design approach to EMB ECU design has been
emphasized because of its safety-critical functions, which are executed
with the aid of many electric actuators, sensors, and application
software. Based on hazard analysis and risk assessment according to
ISO26262, the EMB system should be ASIL-D-compliant, the highest
ASIL level. To this end, an external signature watchdog and an
Infineon 32-bit microcontroller TriCore are used to reduce risks
considering common-cause hardware failure. Moreover, a software
design method is introduced for implementing functional
safety-oriented monitoring functions based on an asymmetric dual
core architecture considering redundancy and diversity. The validity
of the proposed ECU design approach is verified by using the EMB
Hardware-In-the-Loop (HILS) system, which consists of the EMB
assembly, actuator ECU, a host PC, and a few debugging devices.
Furthermore, it is shown that the existing sensor fault tolerant control
system can be used more effectively for mitigating the effects of
hardware and software faults by applying the proposed ECU design
method.