Abstract: Primary progressive aphasia (PPA) is a neurodegenerative disease similar to frontotemporal and semantic dementia, while having a different clinical image and anatomic pathology topography. Nonetheless, they are often included under an umbrella term: frontotemporal lobar degeneration (FTLD). In the study, examples of diagnosing PPA are presented through the multidisciplinary lens of specialists from different fields (neurologists, psychiatrists, clinical speech therapists, clinical neuropsychologists and others) using a variety of diagnostic tools such as MR, PET/CT, genetic screening and neuropsychological and logopedic methods. Thanks to that, specialists can get a better and clearer understanding of PPA diagnosis. The study summarizes the concrete procedures and results of different specialists while diagnosing PPA in a patient of younger middle age and illustrates the importance of multidisciplinary approach to differential diagnosis of PPA.
Abstract: Modeling dam-break flows over non-flat beds requires
an accurate representation of the topography which is the main
source of uncertainty in the model. Therefore, developing robust
and accurate techniques for reconstructing topography in this class
of problems would reduce the uncertainty in the flow system. In
many hydraulic applications, experimental techniques have been
widely used to measure the bed topography. In practice, experimental
work in hydraulics may be very demanding in both time and cost.
Meanwhile, computational hydraulics have served as an alternative
for laboratory and field experiments. Unlike the forward problem,
the inverse problem is used to identify the bed parameters from the
given experimental data. In this case, the shallow water equations
used for modeling the hydraulics need to be rearranged in a way
that the model parameters can be evaluated from measured data.
However, this approach is not always possible and it suffers from
stability restrictions. In the present work, we propose an adaptive
optimal control technique to numerically identify the underlying bed
topography from a given set of free-surface observation data. In this
approach, a minimization function is defined to iteratively determine
the model parameters. The proposed technique can be interpreted
as a fractional-stage scheme. In the first stage, the forward problem
is solved to determine the measurable parameters from known data.
In the second stage, the adaptive control Ensemble Kalman Filter is
implemented to combine the optimality of observation data in order to
obtain the accurate estimation of the topography. The main features
of this method are on one hand, the ability to solve for different
complex geometries with no need for any rearrangements in the
original model to rewrite it in an explicit form. On the other hand, its
achievement of strong stability for simulations of flows in different
regimes containing shocks or discontinuities over any geometry.
Numerical results are presented for a dam-break flow problem over
non-flat bed using different solvers for the shallow water equations.
The robustness of the proposed method is investigated using different
numbers of loops, sensitivity parameters, initial samples and location
of observations. The obtained results demonstrate high reliability and
accuracy of the proposed techniques.
Abstract: Raindrops and overland flow both are erosive parameters but they do not act by the same way. The overland flow alone tends to shear the soil horizontally and concentrates into rills. In the presence of rain, the soil particles are removed from the soil surface in the form of a uniform sheet layer. In addition to this, raindrops falling on the flow roughen the water and soil surface depending on the flow depth, and retard the velocity, therefore influence shear velocity and Manning’s factor. To investigate this part, agricultural sandy soil, rainfall simulator and a laboratory soil tray of 0.2x1x3 m were the base of this work. Five overland flow depths of 0; 3.28; 4.28; 5.16; 5.60; 5.80 mm were generated under a rainfall intensity of 217.2 mm/h. Sediment concentration control is based on the proportionality of depth/microtopography. The soil loose is directly related to the presence of rain splash on thin sheet flow. The effect of shear velocity on sediment concentration is limited by the value of 5.28 cm/s. In addition to this, the rain splash reduces the soil roughness by breaking the soil crests. The rainfall intensity is the major factor influencing depth and soil erosion. In the presence of rainfall, the shear velocity of the flow is due to two simultaneous effects. The first, which is horizontal, comes from the flow and the second, vertical, is due to the raindrops.
Abstract: Urban flooding resulting from a sudden release of
water due to dam-break or excessive rainfall is a serious threatening
environment hazard, which causes loss of human life and large
economic losses. Anticipating floods before they occur could
minimize human and economic losses through the implementation
of appropriate protection, provision, and rescue plans. This work
reports on the numerical modelling of flash flood propagation
in urban areas after an excessive rainfall event or dam-break.
A two-dimensional (2D) depth-averaged shallow water model is
used with a refined unstructured grid of triangles for representing
the urban area topography. The 2D shallow water equations are
solved using a second-order well-balanced discontinuous Galerkin
scheme. Theoretical test case and three flood events are described
to demonstrate the potential benefits of the scheme: (i) wetting and
drying in a parabolic basin (ii) flash flood over a physical model of
the urbanized Toce River valley in Italy; (iii) wave propagation on
the Reyran river valley in consequence of the Malpasset dam-break
in 1959 (France); and (iv) dam-break flood in October 1982 at the
town of Sumacarcel (Spain). The capability of the scheme is also
verified against alternative models. Computational results compare
well with recorded data and show that the scheme is at least as
efficient as comparable second-order finite volume schemes, with
notable efficiency speedup due to parallelization.
Abstract: The paper will focus on the strategic development
deriving from the evolution of the traditional courtyard spatial
organization towards a new, contemporary sustainable way of living.
New sustainable approaches that engulf the social issues, the notion
of place, the understanding of weather architecture blended together
with the bioclimatic behavior will be seen through a series of
experimental case studies in the island of Cyprus, inspired and
originated from its traditional wisdom, ranging from small scale of
living to urban interventions. Weather and nature will be seen as co-architectural authors with
architects. Furthermore, the building will be seen not as an object but
rather as a vessel of human activities. This will further enhance the
notion of merging the material and immaterial, the built and unbuilt,
subject-human, and the object-building. This eventually will enable
to generate the discussion of the understanding of the building in
relation to the place and its inhabitants, where the human topography
is more important than the material topography. The specificities of
the divided island and the dealing with sites that are in vicinity with
the diving Green Line will further trigger explorations dealing with
the regeneration issues and the social sustainability offering
unprecedented opportunities for innovative sustainable ways of
living. Opening up a discourse with premises of weather-nature, materialimmaterial,
human-material topographies in relation to the contested
sites of the borders will lead us to develop innovative strategies for a
profound, both technical and social sustainability, which fruitfully
yields to innovative living built environments, responding to the ever
changing environmental and social needs. As a starting point, a case study in Kaimakli in Nicosia, a
refurbishment with an extension of a traditional house, already
engulfs all the traditional/ vernacular wisdom of the bioclimatic
architecture. The project focusses on the direct and quite obvious
bioclimatic features such as south orientation and cross ventilation.
Furthermore, it tries to reinvent the adaptation of these parameters in
order to turn the whole house to a contemporary living environment.
In order to succeed this, evolutions of traditional architectural
elements and spatial conditions are integrated in a way that does not
only respond to some certain weather conditions, but they integrate
and blend the weather within the built environment. A series of
innovations aiming at maximum flexibility is proposed. The house
can finally be transformed into a winter enclosure, while for the most
part of the year it turns into a ‘camping’ living environment. Parallel to experimental interventions in existing traditional units,
we will proceed examining the implementation of the same
developed methodology in designing living units and complexes.
Malleable courtyard organizations that attempt to blend the
traditional wisdom with the contemporary needs for living, the
weather and nature with the built environment will be seen tested in
both horizontal and vertical developments. Social activities are seen as directly affected and forged by the
weather conditions thus generating a new social identity of people where people are directly involved and interacting with the weather.
The human actions and interaction with the built, material
environment in order to respond to weather will be seen as the result
of balancing the social with the technological sustainability, the
immaterial, and the material aspects of the living environment.
Abstract: Nowadays spinal deformities are very frequent
problems among teenagers. Scheuermann disease is a one
dimensional deformity of the spine, but it has prevalence over 11% of
the children. A traditional technology, the moiré method was used by
us for screening and diagnosing this type of spinal deformity. A
LabVIEW program has been developed to evaluate the moiré pictures
of patients with Scheuermann disease. Two different solutions were
tested in this computer program, the extreme and the inflexion point
calculation methods. Effects using these methods were compared and
according to the results both solutions seemed to be appropriate.
Statistical results showed better efficiency in case of the extreme
search method where the average difference was only 6,09⁰.
Abstract: A well balanced numerical scheme based on
stationary waves for shallow water flows with arbitrary topography
has been introduced by Thanh et al. [18]. The scheme was
constructed so that it maintains equilibrium states and tests indicate
that it is stable and fast. Applying the well-balanced scheme for the
one-dimensional shallow water equations, we study the early shock
waves propagation towards the Phuket coast in Southern Thailand
during a hypothetical tsunami. The initial tsunami wave is generated
in the deep ocean with the strength that of Indonesian tsunami of
2004.
Abstract: This paper describes the optimization of a complex
dairy farm simulation model using two quite different methods of
optimization, the Genetic algorithm (GA) and the Lipschitz
Branch-and-Bound (LBB) algorithm. These techniques have been
used to improve an agricultural system model developed by Dexcel
Limited, New Zealand, which describes a detailed representation of
pastoral dairying scenarios and contains an 8-dimensional parameter
space. The model incorporates the sub-models of pasture growth and
animal metabolism, which are themselves complex in many cases.
Each evaluation of the objective function, a composite 'Farm
Performance Index (FPI)', requires simulation of at least a one-year
period of farm operation with a daily time-step, and is therefore
computationally expensive. The problem of visualization of the
objective function (response surface) in high-dimensional spaces is
also considered in the context of the farm optimization problem.
Adaptations of the sammon mapping and parallel coordinates
visualization are described which help visualize some important
properties of the model-s output topography. From this study, it is
found that GA requires fewer function evaluations in optimization
than the LBB algorithm.
Abstract: This study investigated the seasonal prevalence of
Aedes aegypti and Ae. albopictus larvae in three topographical areas
(i.e. mangrove, rice paddy and mountainous areas). Samples were
collected from 300 households in both wet and dry seasons in nine
districts in Nakhon Si Thammarat province. Ae. aegypti and Ae.
albopictus were found in 21 out of 29 types of water containers in
mangrove, rice paddy and mountainous areas. Ae. aegypti and Ae.
albopictus laid eggs in different container types depending on season
and topographical areas. Ae. aegypti larvae were found most in metal
box in mangrove and mountainous areas in wet season. Ae.
albopictus larvae were also found most in metal box in mangrove and
mountainous areas in both wet and dry seasons. All Ae. albopictus
larval indices were higher than Ae. aegypti larval indices in all three
topographical areas and both seasons. HI and BI did not differ in
three topographical areas but differed between Aedes sp. HI for both
Ae. aegypti and Ae. albopictus in all three topographical areas in both
seasons were greater than 10 %, except Aedes aegypti in rice paddy
area in wet season. This indicated high risks of DHF transmission in
these areas.