Abstract: Matrix metalloproteinase-3 (MMP3) is key member
of the MMP family, and is known to be present in coronary
atherosclerotic. Several studies have demonstrated that MMP-3
5A/6A polymorphism modify each transcriptional activity in allele
specific manner. We hypothesized that this polymorphism may play
a role as risk factor for development of coronary stenosis. The aim of
our study was to estimate MMP-3 (5A/6A) gene polymorphism on
interindividual variability in risk for coronary stenosis in an Iranian
population.DNA was extracted from white blood cells and genotypes
were obtained from coronary stenosis cases (n=95) and controls
(n=100) by PCR (polymerase chain reaction) and restriction
fragment length polymorphism techniques. Significant differences
between cases and controls were observed for MMP3 genotype
frequencies (X2=199.305, p< 0.001); the 6A allele was less
frequently seen in the control group, compared to the disease group
(85.79 vs. 78%, 6A/6A+5A/6A vs. 5A/5A, P≤0.001). These data
imply the involvement of -1612 5A/6A polymorphism in coronary
stenosis, and suggest that probably the 6A/6A MMP-3 genotype is a
genetic susceptibility factor for coronary stenosis.
Abstract: In single trial analysis, when using Principal
Component Analysis (PCA) to extract Visual Evoked Potential
(VEP) signals, the selection of principal components (PCs) is an
important issue. We propose a new method here that selects only
the appropriate PCs. We denote the method as selective eigen-rate
(SER). In the method, the VEP is reconstructed based on the rate
of the eigen-values of the PCs. When this technique is applied on
emulated VEP signals added with background
electroencephalogram (EEG), with a focus on extracting the
evoked P3 parameter, it is found to be feasible. The improvement
in signal to noise ratio (SNR) is superior to two other existing
methods of PC selection: Kaiser (KSR) and Residual Power (RP).
Though another PC selection method, Spectral Power Ratio (SPR)
gives a comparable SNR with high noise factors (i.e. EEGs), SER
give more impressive results in such cases. Next, we applied SER
method to real VEP signals to analyse the P3 responses for
matched and non-matched stimuli. The P3 parameters extracted
through our proposed SER method showed higher P3 response for
matched stimulus, which confirms to the existing neuroscience
knowledge. Single trial PCA using KSR and RP methods failed to
indicate any difference for the stimuli.
Abstract: An active RC filters with a 880 / 1760 MHz dual bandwidth tuning ability is present for 60 GHz unlicensed band applications. A third order Butterworth low-pass filter utilizes two Cherry-Hooper amplifiers to satisfy the very high bandwidth requirements of an amplifier. The low-pass filter is fabricated in 90nm standard CMOS process. Drawing 6.7 mW from 1.2 V power supply, the low frequency gains of the filter are -2.5 and -4.1 dB, and the output third order intercept points (OIP3) are +2.2 and +1.9 dBm for the single channel and channel bonding conditions, respectively.
Abstract: Champs Bourcin black grape originated from
Aquitaine, France and planted in Sapa, Lao cai provice, exhibited
high total acidity (11.72 g/L). After 9 days of alcoholic fermentation
at 25oC using Saccharomyces cerevisiae UP3OY5 strain, the ethanol
concentration of wine was 11.5% v/v, however the sharp sour taste of
wine has been found. The malolactic fermentation (MLF) was carried
out by Oenococcus oeni ATCCBAA-1163 strain which had been preadapted
to acid (pH 3-4) and ethanol (8-12%v/v) conditions. We
obtained the highest vivability (83.2%) upon malolactic fermentation
after 5 days at 22oC with early stationary phase O. oeni cells preadapted
to pH 3.5 and 8% v/v ethanol in MRS medium. The malic
acid content in wine was decreased from 5.82 g/L to 0.02 g/L after
MLF (21 days at 22oC). The sensory quality of wine was
significantly improved.
Abstract: In this study, a synthetic pathway was created by
assembling genes from Clostridium butyricum and Escherichia coli
in different combinations. Among the genes were dhaB1 and dhaB2
from C. butyricum VPI1718 coding for glycerol dehydratase (GDHt)
and its activator (GDHtAc), respectively, involved in the conversion
of glycerol to 3-hydroxypropionaldehyde (3-HPA). The yqhD gene
from E.coli BL21 was also included which codes for an NADPHdependent
1,3-propanediol oxidoreductase isoenzyme (PDORI)
reducing 3-HPA to 1,3-propanediol (1,3-PD). Molecular modeling
analysis indicated that the conformation of fusion protein of YQHD
and DHAB1 was favorable for direct molecular channeling of the
intermediate 3-HPA. According to the simulation results, the yqhD
and dhaB1 gene were assembled in the upstream of dhaB2 to express
a fusion protein, yielding the recombinant strain E. coliBL21
(DE3)//pET22b+::yqhD-dhaB1_dhaB2 (strain BP41Y3). Strain
BP41Y3 gave 10-fold higher 1,3-PD concentration than E. coliBL21
(DE3)//pET22b+::yqhD-dhaB1_dhaB2 (strain BP31Y2) expressing
the recombinant enzymes simultaneously but in a non-fusion mode.
This is the first report using a gene fusion approach to enhance the
biological conversion of glycerol to the value added compound 1,3-
PD.
Abstract: This paper aims to develop an algorithm of finite
capacity material requirement planning (FCMRP) system for a multistage
assembly flow shop. The developed FCMRP system has two
main stages. The first stage is to allocate operations to the first and
second priority work centers and also determine the sequence of the
operations on each work center. The second stage is to determine the
optimal start time of each operation by using a linear programming
model. Real data from a factory is used to analyze and evaluate the
effectiveness of the proposed FCMRP system and also to guarantee a
practical solution to the user. There are five performance measures,
namely, the total tardiness, the number of tardy orders, the total
earliness, the number of early orders, and the average flow-time. The
proposed FCMRP system offers an adjustable solution which is a
compromised solution among the conflicting performance measures.
The user can adjust the weight of each performance measure to
obtain the desired performance. The result shows that the combination
of FCMRP NP3 and EDD outperforms other combinations
in term of overall performance index. The calculation time for the
proposed FCMRP system is about 10 minutes which is practical for
the planners of the factory.
Abstract: The nickel and gold nanoclusters as supported
catalysts were analyzed by XAS, XRD and XPS in order to
determine their local, global and electronic structure. The present
study has pointed out a strong deformation of the local structure of
the metal, due to its interaction with oxide supports. The average
particle size, the mean squares of the microstrain, the particle size
distribution and microstrain functions of the supported Ni and Au
catalysts were determined by XRD method using Generalized Fermi
Function for the X-ray line profiles approximation. Based on EXAFS
analysis we consider that the local structure of the investigated
systems is strongly distorted concerning the atomic number pairs.
Metal-support interaction is confirmed by the shape changes of the
probability densities of electron transitions: Ni K edge (1s →
continuum and 2p), Au LIII-edge (2p3/2 → continuum, 6s, 6d5/2 and
6d3/2). XPS investigations confirm the metal-support interaction at
their interface.
Abstract: In this work, we present for the first time in our perception an efficient digital watermarking scheme for mpeg audio layer 3 files that operates directly in the compressed data domain, while manipulating the time and subband/channel domain. In addition, it does not need the original signal to detect the watermark. Our scheme was implemented taking special care for the efficient usage of the two limited resources of computer systems: time and space. It offers to the industrial user the capability of watermark embedding and detection in time immediately comparable to the real music time of the original audio file that depends on the mpeg compression, while the end user/audience does not face any artifacts or delays hearing the watermarked audio file. Furthermore, it overcomes the disadvantage of algorithms operating in the PCMData domain to be vulnerable to compression/recompression attacks, as it places the watermark in the scale factors domain and not in the digitized sound audio data. The strength of our scheme, that allows it to be used with success in both authentication and copyright protection, relies on the fact that it gives to the users the enhanced capability their ownership of the audio file not to be accomplished simply by detecting the bit pattern that comprises the watermark itself, but by showing that the legal owner knows a hard to compute property of the watermark.
Abstract: This work describes the aerodynamic characteristic for
aircraft wing model with and without bird feather like winglet. The
aerofoil used to construct the whole structure is NACA 653-218
Rectangular wing and this aerofoil has been used to compare the
result with previous research using winglet. The model of the
rectangular wing with bird feather like winglet has been fabricated
using polystyrene before design using CATIA P3 V5R13 software
and finally fabricated in wood. The experimental analysis for the
aerodynamic characteristic for rectangular wing without winglet,
wing with horizontal winglet and wing with 60 degree inclination
winglet for Reynolds number 1.66×105, 2.08×105 and 2.50×105 have
been carried out in open loop low speed wind tunnel at the
Aerodynamics laboratory in Universiti Putra Malaysia. The
experimental result shows 25-30 % reduction in drag coefficient and
10-20 % increase in lift coefficient by using bird feather like winglet
for angle of attack of 8 degree.
Abstract: In this paper, a double balanced radio frequency multiplier
is presented which is customized for transmitted reference
ultra wideband (UWB) receivers. The multiplier uses 90nm model
parameters and exploits compensating transistors to provide controllable
gain for a Gilbert core. After performing periodic and quasiperiodic
non linear analyses the RF mixer (multiplier) achieves a
voltage conversion gain of 16 dB and a DSB noise figure of 8.253
dB with very low power consumption. A high degree of LO to RF
isolation (in the range of -94dB), RF to IF isolation (in the range of
-95dB) and LO to IF isolation (in the range of -143dB) is expected
for this design with an input-referred IP3 point of -1.93 dBm and an
input referred 1 dB compression point of -10.67dBm. The amount of
noise at the output is 7.7 nV/√Hz when the LO input is driven by
a 10dBm signal. The mixer manifests better results when compared
with other reported multiplier circuits and its Zero-IF performance
ensures its applicability as TR-UWB multipliers.
Abstract: In this paper, the Lennard -Jones potential is applied
to molecules of liquid argon as well as its vapor and platinum as solid
surface in order to perform a non-equilibrium molecular dynamics
simulation to study the microscopic aspects of liquid-vapor-solid
interactions. The channel is periodic in x and y directions and along z
direction it is bounded by atomic walls. It was found that density of
the liquids near the solid walls fluctuated greatly and that the
structure was more like a solid than a liquid. This indicates that the
interactions of solid and liquid molecules are very strong. The
resultant surface tension, liquid density and vapor density are found
to be well predicted when compared with the experimental data for
argon. Liquid and vapor densities were found to depend on the cutoff
radius which induces the use of P3M (particle-particle particle-mesh)
method which was implemented for evaluation of force and surface
tension.
Abstract: A 2.4GHz (RF) down conversion Gilbert Cell mixer,
implemented in a 0.18-μm CMOS technology with a 1.8V supply, is
presented. Current bleeding (charge injection) technique has been
used to increase the conversion gain and the linearity of the mixer.
The proposed mixer provides 10.75 dB conversion gain ( C G ) with
14.3mw total power consumption. The IIP3 and 1-dB compression
point of the mixer are 8dbm and -4.6dbm respectively, at 300 MHz
IF frequencies. Comparing the current design against the
conventional mixer design, demonstrates better performance in the
conversion gain, linearity, noise figure and port-to-port isolation.
Abstract: In this paper, a new robust audio fingerprinting
algorithm in MP3 compressed domain is proposed with high
robustness to time scale modification (TSM). Instead of simply
employing short-term information of the MP3 stream, the new
algorithm extracts the long-term features in MP3 compressed domain
by using the modulation frequency analysis. Our experiment has
demonstrated that the proposed method can achieve a hit rate of
above 95% in audio retrieval and resist the attack of 20% TSM. It has
lower bit error rate (BER) performance compared to the other
algorithms. The proposed algorithm can also be used in other
compressed domains, such as AAC.
Abstract: This paper presented the technique of robot control by event-related potentials (ERPs) of brain waves. Based on the proposed technique, severe physical disabilities can free browse outside world. A specific component of ERPs, N2P3, was found and used to control the movement of robot and the view of camera on the designed brain-computer interface (BCI). Users only required watching the stimuli of attended button on the BCI, the evoked potentials of brain waves of the target button, N2P3, had the greatest amplitude among all control buttons. An experimental scene had been constructed that the robot required walking to a specific position and move the view of camera to see the instruction of the mission, and then completed the task. Twelve volunteers participated in this experiment, and experimental results showed that the correct rate of BCI control achieved 80% and the average of execution time was 353 seconds for completing the mission. Four main contributions included in this research: (1) find an efficient component of ERPs, N2P3, for BCI control, (2) embed robot's viewpoint image into user interface for robot control, (3) design an experimental scene and conduct the experiment, and (4) evaluate the performance of the proposed system for assessing the practicability.
Abstract: A design flow of multi-standard down-conversion
CMOS mixers for three modern standards: Global System Mobile,
Digital Enhanced Cordless Telephone and Universal Mobile
Telecommunication Systems is presented. Three active mixer-s
structures are studied. The first is based on the Gilbert cell which
gives a tolerable noise figure and linearity with a low conversion
gain. The second and third structures use the current bleeding and
charge injection techniques in order to increase the conversion gain.
An improvement of about 2 dB of the conversion gain is achieved
without a considerable degradation of the other characteristics. The
models used for noise figure, conversion gain and IIP3 used are
studied. This study describes the nature of trade-offs inherent in such
structures and gives insights that help in identifying which structure
is better for given conditions.
Abstract: In this paper, we propose a new approach to query-by-humming, focusing on MP3 songs database. Since MP3 songs are much more difficult in melody representation than symbolic performance data, we adopt to extract feature descriptors from the vocal sounds part of the songs. Our approach is based on signal filtering, sub-band spectral processing, MDCT coefficients analysis and peak energy detection by ignorance of the background music as much as possible. Finally, we apply dual dynamic programming algorithm for feature similarity matching. Experiments will show us its online performance in precision and efficiency.