Abstract: Chikungunya virus (CHICKV) is an arboviruses belonging to family Tagoviridae and is transmitted to human through by mosquito (Aedes aegypti and Aedes albopictus) bite. A large outbreak of chikungunya has been reported in India between 2006 and 2007, along with several other countries from South-East Asia and for the first time in Europe. It was for the first time that the CHICKV outbreak has been reported with mortality from Reunion Island and increased mortality from Asian countries. CHICKV affects all age groups, and currently there are no specific drugs or vaccine to cure the disease. The need of antiviral agents for the treatment of CHICKV infection and the success of virtual screening against many therapeutically valuable targets led us to carry out the structure based drug design against Chikungunya nSP2 protease (PDB: 3TRK). Highthroughput virtual screening of publicly available databases, ZINC12 and BindingDB, has been carried out using the Openeye tools and Schrodinger LLC software packages. Openeye Filter program has been used to filter the database and the filtered outputs were docked using HTVS protocol implemented in GLIDE package of Schrodinger LLC. The top HITS were further used for enriching the similar molecules from the database through vROCS; a shape based screening protocol implemented in Openeye. The approach adopted has provided different scaffolds as HITS against CHICKV protease. Three scaffolds: Indole, Pyrazole and Sulphone derivatives were selected based on the docking score and synthetic feasibility. Derivatives of Pyrazole were synthesized and submitted for antiviral screening against CHICKV.
Abstract: Recent financial international scandals around the world have led to a number of investigations into the effectiveness of corporate governance practices and audit quality. Although evidence of corporate governance practices and audit quality exists from developed economies, very scanty studies have been conducted in Egypt where corporate governance is just evolving. Therefore, this study provides evidence on the effectiveness of corporate governance practices and audit quality from a developing country. The data for analysis are gathered from the top 50 most active companies in the Egyptian Stock Exchange, covering the three year period 2007-2009. Logistic regression was used in investigating the questions that were raised in the study. Findings from the study show that board independence; CEO duality and audit committees significantly have relationship with audit quality. The results also, indicate that institutional investor and managerial ownership have no significantly relationship with audit quality. Evidence also exist that size of the company; complexity and business leverage are important factors in audit quality for companies quoted on the Egypt Stock Exchange.
Abstract: The present disposal routes of sewage sludge represent a critical environmental issue in Egypt. Recently, there has been an increasing concern about sewage sludge management due to the environmental risks, which resulted from the fast expansion of wastewater treatment plants without equal attention in dealing with the produced sludge. This paper discusses the current situation of sewage sludge management in Egypt presenting a brief overview of the existing wastewater treatment plants, sludge production and characteristics as well as options of beneficial use and potential demand of sewage sludge under Egyptian conditions. The characteristics of sewage sludge are discussed considering the results of own sampling and analysis as well as previous studies. Furthermore, alternative treatment scenarios for sewage sludge, which have been recently developed in Egypt, are discussed and perspectives for a sustainable agricultural use are outlined.
Abstract: To make use of the limited amounts of water in arid
region, the Iranians developed man-made underground water
channels called qanats (kanats) .In fact, qanats may be considered as
the first long-distance water transfer system. Qanats are an ancient
water transfer system found in arid regions wherein groundwater
from mountainous areas, aquifers and sometimes from rivers, was
brought to points of re-emergence such as an oasis, through one or
more underground tunnels. The tunnels, many of which were
kilometers in length, had designed for slopes to provide gravitational
flow. The tunnels allowed water to drain out to the surface by gravity
to supply water to lower and flatter agricultural land.
Qanats have been an ancient, sustainable system facilitating the
harvesting of water for centuries in Iran, and more than 35 additional
countries of the world such as India, Arabia, Egypt, North Africa,
Spain and even to New world.
There are about 22000 qanats in Iran with 274000 kilometers of
underground conduits all built by manual labor. The amount of
water of the usable qanats of Iran produce is altogether 750 to
1000 cubic meter per second. The longest chain of qanat is
situated in Gonabad region in Khorasan province. It is 70
kilometers long. Qanats are renewable water supply systems that
have sustained agricultural settlement on the Iranian plateau for
millennia. The great advantages of Qanats are no evaporation
during transit, little seepage , no raising of the water- table and no
pollution in the area surrounding the conduits. Qanat systems
have a profound influence on the lives of the water users in Iran, and
conform to Iran-s climate. Qanat allows those living in a desert
environment adjacent to a mountain watershed to create a large oasis
in an otherwise stark environment.
This paper explains qanats structure designs, their history,
objectives causing their creation, construction materials, locations
and their importance in different times, as well as their present
sustainable role in Iran.
Abstract: The Egyptian Bacillus thuringiensis isolate (M5) produce crystal proteins that is toxic against insects was irradiated with UV light to induce mutants. Upon testing 10 of the resulting mutants for their toxicity against cotton leafworm larvae, the three mutants 62, 64 and 85 proved to be the most toxic ones. Upon testing these mutants along with their parental isolate by SDS-PAGE analysis of spores-crystals proteins as well as vegetative cells proteins, new induced bands appeared in the three mutants by UV radiation and also they showed disappearance of some other bands as compared with the wild type isolate. Multiplex PCR technique, with five sets of specific primers, was used to detect the three types of cryI genes cryIAa, cryIAb and cryIAc. Results showed that these three genes exist, as distinctive bands, in the wild type isolate (M5) as well as in mutants 62 and 85, while the mutant 64 had two distinctive bands of cryIAb and cryIAc genes, and a faint band of cryI Aa gene. Finally, these results revealed that mutant 62 is considered as the promising mutant since it is UV resistant, highly toxic against Spodoptera littoralis and active against a wide range of Lepidopteran insects.
Abstract: The potential of entomopathogenic nematodes in suppressing T. squalida population on cauliflower from transplanting to harvest was evaluated. Significant reductions in plant infestation percentage and population density (/m2) were recorded throughout the plantation seasons, 2011 and 2012 before and after spraying the plants. The percent reduction in numbers/m2 was the highest in March for the treatments with Heterorhabditis indica Behera and Heterorhabditis bacteriophora Giza during the plantation season 2011, while at the plantation season 2012, the reduction in population density was the highest in January for Heterorhabditis Indica Behera and in February for H . bacteriophora Giza treatments. In a comparison test with conventional insecticides Hostathion and Lannate, there were no significant differences in control measures resulting from treatments with H. indica Behera, H. bacteriophora Giza and Lannate. At the plantation season is 2012. Also, the treatments reduced the economic threshold of T. squalida on cauliflower in this experiment as compared with before and after spraying with both the two entomopathogenic nematodes at both seasons 2011 and 2012. This means an increase in the marketability of heads harvested as a consequence of monthly treatments.
Abstract: Temperature is one of the most principle factors affects aquaculture system. It can cause stress and mortality or superior environment for growth and reproduction. This paper presents the control of pond water temperature using artificial intelligence technique. The water temperature is very important parameter for shrimp growth. The required temperature for optimal growth is 34oC, if temperature increase up to 38oC it cause death of the shrimp, so it is important to control water temperature. Solar thermal water heating system is designed to supply an aquaculture pond with the required hot water in Mersa Matruh in Egypt. Neural networks are massively parallel processors that have the ability to learn patterns through a training experience. Because of this feature, they are often well suited for modeling complex and non-linear processes such as those commonly found in the heating system. Artificial neural network is proposed to control water temperature due to Artificial intelligence (AI) techniques are becoming useful as alternate approaches to conventional techniques. They have been used to solve complicated practical problems. Moreover this paper introduces a complete mathematical modeling and MATLAB SIMULINK model for the aquaculture system. The simulation results indicate that, the control unit success in keeping water temperature constant at the desired temperature by controlling the hot water flow rate.
Abstract: Bentonitic material from South Aswan, Egypt was evaluated in terms of mineral-ogy and chemical composition as bleaching clay in refining of transformer oil before and after acid activation and thermal treatment followed by acid leaching using HCl and H2SO4 for different contact times. Structural modification and refining power of bento-nite were investigated during modification by means of X-ray diffraction and infrared spectroscopy. The results revealed that the activated bentonite could be used for refining of transformer oil. The oil parameters such as; dielectric strength, viscosity and flash point had been improved. The dielectric breakdown strength of used oil increased from 29 kV for used oil treated with unactivated bentonite to 74 kV after treatment with activated bentonite. Kinematic Viscosity changed from 19 to 11 mm2 /s after treatment with activated bentonite. However, flash point achieved 149 ºC.
Abstract: The improvement of irrigation systems in the Nile
Delta is one of the most important attempts in Egypt to implement
more effective irrigation technology by improving the existing
irrigation networks. Demand delivery system in the existing irrigation
network is using of mechanical gates structures to automatically
divert water from one portion of an agricultural field to another in the
desired amount and sequence. This paper discusses evaluating main
irrigation networks system under the government managed before
and after improvement systems in the Nile Delta. The overall results
indicate that policy of using the demand delivery concept through
irrigation networks is successful by improving water delivery
performance among them than the rotation delivery concept that used
before. It is provided fair share of water delivery among irrigation
districts and available water in the end of irrigation network,
although this system located in an end of irrigation networks in the
Nile Delta.
Abstract: Two Amphiphilic catalysts, iron (III) dodecylbenzene
sulfonate and nickel (II) dodecylbenzene sulfonate, were synthesized
and used in the catalytic aquathermolysis of heavy crude oil to reduce
its viscosity. The prepared catalysts exhibited good performance in
the aquathermolysis and the viscosity is reduced by ~ 78.9 % for
Egyptian heavy crude oil. The chemical and physical properties of
heavy oil both before and after reaction were investigated by FT-IR,
dynamic viscosity, molecular weight and SARA analysis. The results
indicated that the content of resin, asphaltene, average molecular
weight and sulfur content of heavy oil is reduced after the catalytic
aquathermolysis.
Abstract: The main objective of this paper is to estimate the cost of road traffic accidents in Egypt. The Human Capital (HC) approach, specifically the Gross-Loss-of-Output methodology, is adopted for estimation. Moreover, cost values obtained by previous national literature are updated using the inflation rates. The results indicate an estimated cost of road traffic accidents in Egypt of approximately 10 billion Egyptian Pounds (about $US 1.8 billion) for the year 2008. In addition, it is expected that this cost will rise in 2009 to 11.8 billion Egyptian Pounds (about $US 2.1 billion).
Abstract: Power Factor (PF) is one of the most important parameters in the electrical systems, especially in the water pumping station. The low power factor value of the water pumping stations causes penalty for the electrical bill. There are many methods use for power factor improvement. Each one of them uses a capacitor on the electrical power network. The position of the capacitors is varied depends on many factors such as; voltage level and capacitors rating. Adding capacitors on the motor terminals increase the supply power factor from 0.8 to more than 0.9 but these capacitors cause some problems for the electrical grid network, such as increasing the harmonic contents of the grid line voltage. In this paper the effects of using capacitors in the water pumping stations to improve the power factor value on the harmonic contents of the electrical grid network are studied. One of large water pumping stations in Kafr El-Shikh Governorate in Egypt was used, as a case study. The effect of capacitors on the line voltage harmonic contents is measured. The station uses capacitors to improve the PF values at the 1 lkv grid network. The power supply harmonics values are measured by a power quality analyzer at different loading conditions. The results showed that; the capacitors improved the power factor value of the feeder and its value increased than 0.9. But the THD values are increased by adding these capacitors. The harmonic analysis showed that; the 13th, 17th, and 19th harmonics orders are increased also by adding the capacitors.
Abstract: Where renewable energy sources, solar, hydro, wind are available the remote communities and businesses can be provided with the most reliable and affordable source of electrical energy. This paper presents a model of safari rest contains all the necessary services for the interested tourists who visit the safari Sinai desert. The PV energy system provides the rural energy needs of remote communities. A photovoltaic renewable energy system is designed to feed the global Ac and Dc electrical required load of this safari rest . The benefits of photovoltaic renewable energy at rural applications are its versatility and convenience. This model of safari rest must be taken in consideration by Egyptian Government as it will provide the tourism plane by new interested tourism field which put a big spot on Red sea area: El Ghordaka.
Abstract: Fuel cells have become one of the major areas of
research in the academia and the industry. The goal of most fish
farmers is to maximize production and profits while holding labor
and management efforts to the minimum. Risk of fish kills, disease
outbreaks, poor water quality in most pond culture operations,
aeration offers the most immediate and practical solution to water
quality problems encountered at higher stocking and feeding rates.
Many units of aeration system are electrical units so using a
continuous, high reliability, affordable, and environmentally friendly
power sources is necessary. Aeration of water by using PEM fuel cell
power is not only a new application of the renewable energy, but
also, it provides an affordable method to promote biodiversity in
stagnant ponds and lakes. This paper presents a new design and
control of PEM fuel cell powered a diffused air aeration system for a
shrimp farm in Mersa Matruh in Egypt. Also Artificial intelligence
(AI) techniques control is used to control the fuel cell output power
by control input gases flow rate. Moreover the mathematical
modeling and simulation of PEM fuel cell is introduced. A
comparison study is applied between the performance of fuzzy logic
control (FLC) and neural network control (NNC). The results show
the effectiveness of NNC over FLC.
Abstract: Desert regions around the Nile valley in Upper Egypt
contain great extent of swelling soil. Many different comment
procedures of treatment of the swelling soils for construction such as
pre-swelling, load balance OR soil replacement. One of the measure
factors which affect the level of the aggressiveness of the swelling
soil is the direction of the infiltration water directions within the
swelling soils. In this paper a physical model was installed to
measure the effect of water on the swelling soil with replacement
using fatty acid distillation residuals (FADR) mixed with sand as
thick sand-FADR mixture to prevent the water pathway arrive to the
swelling soil. Testing program have been conducted on different
artificial samples with different sand to FADR contents ratios (4%,
6%, and 9%) to get the optimum value fulfilling the impermeable
replacement. The tests show that a FADR content of 9% is sufficient
to produce impermeable replacement.
Abstract: Seasonal survey of freshwater snails in different water
courses in Egypt during two successive years included 13 snail
species. They represented by Biomphalaria alexandrina, Bulinus
truncatus, Physa acuta, Helisoma duryi, Lymnaea natalensis,
Planorbis pantries, Cleopatra bulimoides, Lanistes carinatus,
Bellamya unicolor, Melanoides tuberculata, Theodoxus niloticus,
Succinia cleopatra and Valvata nilotica. B. alexandrina was most
abundant during autumn and spring represented by 26and14
snails/site, respectively. B. truncatus was most abundant during
winter (7.7and3.6snails/site) of the two years, respectively. L.
natalensis was represented by 7snails/site in summer. The tolerance
of different snail species to the chemical elements was determined
seasonally and correlated to their abundance. In spring, autumn and
winter, B. alexandrina was significantly found to live under the
highest level of Pb, Cd,Cu, Na, K and Ca concentrations than the
other species (p
Abstract: “Dengue" is an African word meaning “bone
breaking" because it causes severe joint and muscle pain that feels
like bones are breaking. It is an infectious disease mainly transmitted
by female mosquito, Aedes aegypti, and causes four serotypes of
dengue viruses. In recent years, a dramatic increase in the dengue
fever confirmed cases around the equator-s belt has been reported.
Several conventional indices have been designed so far to monitor the
transmitting vector populations known as House Index (HI),
Container Index (CI), Breteau Index (BI). However, none of them
describes the adult mosquito population size which is important to
direct and guide comprehensive control strategy operations since
number of infected people has a direct relationship with the vector
density. Therefore, it is crucial to know the population size of the
transmitting vector in order to design a suitable and effective control
program. In this context, a study is carried out to report a new
statistical index, ABURAS Index, using Poisson distribution based
on the collection of vector population in Jeddah Governorate, Saudi Arabia.
Abstract: With the beginning of the new century, man still faces
many challenges in how to form and develop his urban environment. To meet these challenges, many cities have tried to develop its visual
image. This is by transforming their urban environment into a branded visual image; this is at the level of squares, the main roads, the borders, and the landmarks.
In this realm, the paper aims at activating the role of branded urban spaces as an approach for the development of visual image of cities, especially in Egypt. It concludes the need to recognize the importance of developing the visual image in Egypt, through directing the urban planners to the important role of such spaces in achieving sustainability.
Abstract: The problem of wastewater treatment in Egypt is a two-fold problem; the first part concerning the existing rural areas, the second one dealing with new industrial/domestic areas. In Egypt several agricultural projects have been initiated by the government and the private sector as well, in order to change its infrastructure. As a reliable energy source, photovoltaic pumping systems have contributed to supply water for local rural communities worldwide; they can also be implemented to solve the problem “wastewater environment pollution". The solution of this problem can be categorised as recycle process. In addition, because of regional conditions past technologies are being reexamined to select a smallscale treatment system requiring low construction and maintenance costs. This paper gives the design guidelines of a Photovoltaic Small- Scale Wastewater Treatment Plant (PVSSWTP) based on technologies that can be transferred.
Abstract: Public parks are placed high on the research agenda, with many studies addressing their social, economic and environment influences in different countries around the world. They have been recognized as contributors to the physical quality of urban environments. Recently, a broader view of public parks has emerged. This view goes well beyond the traditional value of parks as places for more recreation and visual delight, to depict them as valuable contributors to broader strategic objectives, such as property values, place attractiveness, job opportunities, social belonging, public health, tourist development, and improving the overall quality of life. This research examines the role of public parks in enhancing the quality of human life in Egyptian environment. It measures 'quality of life' in terms of 'human needs' and 'well-being'. This should open ways for policymakers, practitioners, researchers and the public to realize the potentials of public parks towards improving the quality of life.