Abstract: This paper describes the design of new method of
propagation delay measurement in micro and nanostructures during
characterization of ASIC standard library cell. Providing more
accuracy timing information about library cell to the design team we
can improve a quality of timing analysis inside of ASIC design flow
process. Also, this information could be very useful for semiconductor
foundry team to make correction in technology process. By
comparison of the propagation delay in the CMOS element and result
of analog SPICE simulation. It was implemented as digital IP core for
semiconductor manufacturing process. Specialized method helps to
observe the propagation time delay in one element of the standard-cell
library with up-to picoseconds accuracy and less. Thus, the special
useful solutions for VLSI schematic to parameters extraction, basic
cell layout verification, design simulation and verification are
announced.
Abstract: Offset mismatch, gain mismatch, and time-skew error between time-interleaved channels limit the performance of time-interleaved analog-to-digital converters (TIADC). This paper focused on the time-skew error. A new technique for calibrating time-skew error in M-channels TIADC is described, and simulation results are also presented.
Abstract: RFID system, in which we give identification number to each item and detect it with radio frequency, supports more variable service than barcode system can do. For example, a refrigerator with RFID reader and internet connection will automatically notify expiration of food validity to us. But, in spite of its convenience, RFID system has some security threats, because anybody can get ID information of item easily. One of most critical threats is privacy invasion. Existing privacy protection schemes or systems have been proposed, and these schemes or systems defend normal users from attempts that any attacker tries to get information using RFID tag value. But, these systems still have weakness that attacker can get information using analogous value instead of original tag value. In this paper, we mention this type of attack more precisely and suggest 'Tag Broker Model', which can defend it. Tag broker in this model translates original tag value to random value, and user can only get random value. Attacker can not use analogous tag value, because he/she is not able to know original one from it.
Abstract: We present a preliminary x-ray study on human-hair
microstructures for a health-state indicator, in particular a cancer
case. As an uncomplicated and low-cost method of x-ray technique,
the human-hair microstructure was analyzed by wide-angle x-ray
diffractions (XRD) and small-angle x-ray scattering (SAXS). The
XRD measurements exhibited the simply reflections at the d-spacing
of 28 Å, 9.4 Å and 4.4 Å representing to the periodic distance of the
protein matrix of the human-hair macrofibrous and the diameter and
the repeated spacing of the polypeptide alpha helixes of the
photofibrils of the human-hair microfibrous, respectively. When
compared to the normal cases, the unhealthy cases including to the
breast- and ovarian-cancer cases obtained higher normalized ratios of
the x-ray diffracting peaks of 9.4 Å and 4.4 Å. This likely resulted
from the varied distributions of microstructures by a molecular
alteration. As an elemental analysis by x-ray fluorescence (XRF), the
normalized quantitative ratios of zinc(Zn)/calcium(Ca) and
iron(Fe)/calcium(Ca) were determined. Analogously, both Zn/Ca and
Fe/Ca ratios of the unhealthy cases were obtained higher than both of
the normal cases were. Combining the structural analysis by XRD
measurements and the elemental analysis by XRF measurements
exhibited that the modified fibrous microstructures of hair samples
were in relation to their altered elemental compositions. Therefore,
these microstructural and elemental analyses of hair samples will be
benefit to associate with a diagnosis of cancer and genetic diseases.
This functional method would lower a risk of such diseases by the
early diagnosis. However, the high-intensity x-ray source, the highresolution
x-ray detector, and more hair samples are necessarily
desired to develop this x-ray technique and the efficiency would be
enhanced by including the skin and fingernail samples with the
human-hair analysis.
Abstract: Descriptive statistics was performed with the aim to achieve research objective of to investigate lecturers- usage of the mobile technology for teaching. A representative sample of 20 lecturers from the Faculty of Industrial Art & Design Technology of Universiti Industri Selangor (UNISEL), Malaysia was selected as the respondents. The result attested that lecturers fully accept the concept of mobility in learning and game play is appealing concept to support classroom learning. Subsequently, analogous experience on small size of keypad, screen resolution, and navigation could be the major problematic factors to students and affect their mobile learning process. Recommendation for future research is also presented.
Abstract: In this paper, a delayed competitive system with the effect of toxic substances is investigated. With the aid of differential equations with piecewise constant arguments, a discrete analogue of continuous non-autonomous delayed competitive system with the effect of toxic substances is proposed. By using Gaines and Mawhin,s continuation theorem of coincidence degree theory, a easily verifiable sufficient condition for the existence of positive solutions of difference equations is obtained.
Abstract: Severe acute respiratory syndrome (SARS) is a respiratory disease in humans which is caused by the SARS coronavirus. The treatment of coronavirus-associated SARS has been evolving and so far there is no consensus on an optimal regimen. The mainstream therapeutic interventions for SARS involve broad-spectrum antibiotics and supportive care, as well as antiviral agents and immunomodulatory therapy. The Protein- Ligand interaction plays a significant role in structural based drug designing. In the present work we have taken the receptor Angiotensin converting enzyme 2 and identified the drugs that are commonly used against SARS. They are Lopinavir, Ritonavir, Ribavirin, and Oseltamivir. The receptor Angiotensin converting enzyme 2 (ACE-2) was docked with above said drugs and the energy value obtained are as follows, Lopinavir (-292.3), Ritonavir (-325.6), Oseltamivir (- 229.1), Ribavirin (-208.8). Depending on the least energy value we have chosen the best two drugs out of the four conventional drugs. We tried to improve the binding efficiency and steric compatibility of the two drugs namely Ritonavir and Lopinavir. Several modifications were made to the probable functional groups (phenylic, ketonic groups in case of Ritonavir and carboxylic groups in case of Lopinavir respectively) which were interacting with the receptor molecule. Analogs were prepared by Marvin Sketch software and were docked using HEX docking software. Lopinavir analog 8 and Ritonavir analog 11 were detected with significant energy values and are probable lead molecule. It infers that some of the modified drugs are better than the original drugs. Further work can be carried out to improve the steric compatibility of the drug based upon the work done above for a more energy efficient binding of the drugs to the receptor.
Abstract: The Internet and the ever growing applications enable
communities to share and collaborate through common platforms.
However, this growing pattern is not witnessed yet even for elearning.
This paper is based on a doctoral research which aimed at
researching the ways students interact in an online campus and the
supports that they look for and require. Content analysis, based on the
Panchoo/Jaillet methodology, was done on four synchronous
meetings between a tutor and his ten students. The UNIV-Rct ecampus,
analogical to a physical campus, was found to be user
friendly and the students enrolled in a master-s course faced no
difficulties in using it. In addition to the environmental aspects, the
pedagogical implementation of the course has driven the students to
interact and collaborate significantly and this has contributed to
overcome the problems faced by the distance learners. This
completely online model was found to be fruitful in helping distant
learners fight their loneliness and brave their difficulties in a socioconstructivism
approach.
Abstract: Camptothecin (CPT) is a cytotoxic quinoline alkaloid,
which inhibits the DNA enzyme topoisomerase I (topo I). It was
discovered in 1966 by M. E. Wall and M. C. Wani in systematic
screening of natural products for anticancer drugs. It was isolated
from the bark and stem of Camptotheca acuminata (Camptotheca,
Happy tree), a tree native in China. CPT showed remarkable
anticancer activity in preliminary clinical trials but also low
solubility and (high) adverse drug reaction. Because of these
disadvantages synthetic and medicinal chemists have developed
numerous syntheses of Camptothecine [1][2][3] and various
derivatives to increase the benefits of the chemical, with good results.
In our method CPT analogues has be six steps starting from available
material DL Malic acid.
Abstract: In this paper, we use Generalized Hamiltonian systems approach to synchronize a modified sixth-order Chua's circuit, which generates hyperchaotic dynamics. Synchronization is obtained between the master and slave dynamics with the slave being given by an observer. We apply this approach to transmit private information (analog and binary), while the encoding remains potentially secure.
Abstract: Adenylate kinase (AK) catalyse the phosphotransferase
reaction plays an important role in cellular energy homeostasis. The
inhibitors of bacterial AK are useful in the treatment of several
bacterial infections. To the novel inhibitors of AK, docking studies
performed by using the 3D structure of Bacillus stearothermophilus
adenylate kinase from protein data bank (IZIP). 46 Quinoxaline
analogues were docked in 1ZIP and selected the highly interacting
compounds based on their binding energies, for further studies
Abstract: Today, design requirements are extending more and
more from electronic (analogue and digital) to multidiscipline design.
These current needs imply implementation of methodologies to make
the CAD product reliable in order to improve time to market, study
costs, reusability and reliability of the design process.
This paper proposes a high level design approach applied for the
characterization and the optimization of Switched-Current Sigma-
Delta Modulators. It uses the new hardware description language
VHDL-AMS to help the designers to optimize the characteristics of
the modulator at a high level with a considerably reduced CPU time
before passing to a transistor level characterization.
Abstract: Creativity is often based on an unorthodox
recombination of knowledge; in fact: 80% of all innovations use
given knowledge and put it into a new combination. Cross-industry
innovations follow this way of thinking and bring together problems
and solution ideas from different industries. Therefore analogies and
search strategies have to be developed. Taking this path, the
questions where to search, what to search and how to search have to
be answered. Afterwards, the gathered information can be used
within a planned search process. Identified solution ideas have to be
assessed and analyzed in detail for the success promising adaption
planning.
Abstract: Genetic Algorithm has been used to solve wide range of optimization problems. Some researches conduct on applying Genetic Algorithm to analog circuit design automation. These researches show a better performance due to the nature of Genetic Algorithm. In this paper a modified Genetic Algorithm is applied for analog circuit design automation. The modifications are made to the topology of the circuit. These modifications will lead to a more computationally efficient algorithm.
Abstract: The significance of psychology in studying politics
is embedded in philosophical issues as well as behavioural
pursuits. For the former is often associated with Sigmund Freud
and his followers. The latter is inspired by the writings of Harold
Lasswell. Political psychology or psychopolitics has its own
impression on political thought ever since it deciphers the concept
of human nature and political propaganda. More importantly,
psychoanalysis views political thought as a textual content which
needs to explore the latent from the manifest content. In other
words, it reads the text symptomatically and interprets the hidden
truth. This paper explains the paradigm of dream interpretation
applied by Freud. The dream work is a process which has four
successive activities: condensation, displacement, representation
and secondary revision. The texts dealing with political though can
also be interpreted on these principles. Freud's method of dream
interpretation draws its source after the hermeneutic model of
philological research. It provides theoretical perspective and
technical rules for the interpretation of symbolic structures. The
task of interpretation remains a discovery of equivalence of
symbols and actions through perpetual analogies. Psychoanalysis
can help in studying political thought in two ways: to study the text
distortion, Freud's dream interpretation is used as a paradigm
exploring the latent text from its manifest text; and to apply Freud's
psychoanalytic concepts and theories ranging from individual mind
to civilization, religion, war and politics.
Abstract: Bio-electrical responses obtained from freshwater
sediments by employing microbial fuel cell (MFC) technology were
investigated in this experimental study. During the electricity
generation, organic matter in the sediment was microbially oxidized
under anaerobic conditions with an electrode serving as a terminal
electron acceptor. It was found that the sediment organic matter
(SOM) associated with electrochemically-active electrodes became
more humified, aromatic, and polydispersed, and had a higher average
molecular weight, together with the decrease in the quantity of SOM.
The alteration of characteristics of the SOM was analogous to that
commonly observed in the early stage of SOM diagenetic process (i.e.,
humification). These findings including an elevation of the sediment
redox potential present a possibility of the MFC technology as a new
soil/sediment remediation technique based on its potential benefits:
non-destructive electricity generation and bioremediation.
Abstract: In many ways, biomedical analysis is analogous to possibilistic reasoning. In spite of that, there are hardly any applications of possibility theory in biology or medicine. The aim of this work is to demonstrate the use of possibility theory in an epidemiological study. In the paper, we build the possibility distribution for the controlled bloodstream concentrations of any physiologically active substance through few approximate considerations. This possibility distribution is tested later against the empirical histograms obtained from the panel study of the eight different physiologically active substances in 417 individuals.
Abstract: This article discusses the problem of estimating the
orientation of inclined ground on which a human subject stands based
on information provided by the vestibular system consisting of the
otolith and semicircular canals. It is assumed that body segments are
not necessarily aligned and thus forming an open kinematic chain.
The semicircular canals analogues to a technical gyrometer provide a
measure of the angular velocity whereas the otolith analogues to a
technical accelerometer provide a measure of the translational
acceleration. Two solutions are proposed and discussed. The first is
based on a stand-alone Kalman filter that optimally fuses the two
measurements based on their dynamic characteristics and their noise
properties. In this case, no body dynamic model is needed. In the
second solution, a central extended disturbance observer that
incorporates a body dynamic model (internal model) is employed.
The merits of both solutions are discussed and demonstrated by
experimental and simulation results.
Abstract: Harmonic pollution and low power factor in power
systems caused by power converters have been of great concern. To
overcome these problems several converter topologies using
advanced semiconductor devices and control schemes have been
proposed. This investigation is to identify a low cost, small size,
efficient and reliable ac to dc converter to meet the input performance
index of UPS. The performance of single phase and three phase ac to
dc converter along with various control techniques are studied and
compared. The half bridge converter topology with linear current
control is identified as most suitable. It is simple, energy efficient
because of single switch power loss and transformer-less operation of
UPS. The results are validated practically using a prototype built
using IGBT and analog controller. The performance for both single
and three-phase system is verified. Digital implementation of closed
loop control achieves higher reliability. Its cost largely depends on
chosen bit precision. The minimal bit precision for optimum
converter performance is identified as 16-bit with fixed-point
operation. From the investigation and practical implementation it is
concluded that half bridge ac – dc converter along with digital linear
controller meets the performance index of UPS for single and three
phase systems.
Abstract: In Geographic Information System, one of the sources
of obtaining needed geographic data is digitizing analog maps and
evaluation of aerial and satellite photos. In this study, a method will
be discussed which can be used to extract vectorial features and
creating vectorized drawing files for aerial photos. At the same time
a software developed for these purpose. Converting from raster to
vector is also known as vectorization and it is the most important step
when creating vectorized drawing files. In the developed algorithm,
first of all preprocessing on the aerial photo is done. These are;
converting to grayscale if necessary, reducing noise, applying some
filters and determining the edge of the objects etc. After these steps,
every pixel which constitutes the photo are followed from upper left
to right bottom by examining its neighborhood relationship and one
pixel wide lines or polylines obtained. The obtained lines have to be
erased for preventing confusion while continuing vectorization
because if not erased they can be perceived as new line, but if erased
it can cause discontinuity in vector drawing so the image converted
from 2 bit to 8 bit and the detected pixels are expressed as a different
bit. In conclusion, the aerial photo can be converted to vector form
which includes lines and polylines and can be opened in any CAD
application.