Abstract: This paper proposes a low power SRAM based on
five transistor SRAM cell. Proposed SRAM uses novel word-line
decoding such that, during read/write operation, only selected cell
connected to bit-line whereas, in conventional SRAM (CV-SRAM),
all cells in selected row connected to their bit-lines, which in turn
develops differential voltages across all bit-lines, and this makes
energy consumption on unselected bit-lines. In proposed SRAM
memory array divided into two halves and this causes data-line
capacitance to reduce. Also proposed SRAM uses one bit-line and
thus has lower bit-line leakage compared to CV-SRAM.
Furthermore, the proposed SRAM incurs no area overhead, and has
comparable read/write performance versus the CV-SRAM.
Simulation results in standard 0.25μm CMOS technology shows in
worst case proposed SRAM has 80% smaller dynamic energy
consumption in each cycle compared to CV-SRAM. Besides, energy
consumption in each cycle of proposed SRAM and CV-SRAM
investigated analytically, the results of which are in good agreement
with the simulation results.
Abstract: The problem of exponential stability and periodicity for a class of cellular neural networks (DCNNs) with time-varying delays is investigated. By dividing the network state variables into subgroups according to the characters of the neural networks, some sufficient conditions for exponential stability and periodicity are derived via the methods of variation parameters and inequality techniques. These conditions are represented by some blocks of the interconnection matrices. Compared with some previous methods, the method used in this paper does not resort to any Lyapunov function, and the results derived in this paper improve and generalize some earlier criteria established in the literature cited therein. Two examples are discussed to illustrate the main results.
Abstract: In this paper we present a general formalism for the
establishment of the family of selective regressor affine projection
algorithms (SR-APA). The SR-APA, the SR regularized APA (SR-RAPA),
the SR partial rank algorithm (SR-PRA), the SR binormalized
data reusing least mean squares (SR-BNDR-LMS), and the SR normalized
LMS with orthogonal correction factors (SR-NLMS-OCF)
algorithms are established by this general formalism. We demonstrate
the performance of the presented algorithms through simulations in
acoustic echo cancellation scenario.
Abstract: Cancer becomes one of the leading cause of death in
many countries over the world. Fourier-transform infrared (FTIR)
spectra of human lung cancer cells (A549) treated with PMF (natural
product extracted from PM 701) for different time intervals were
examined. Second derivative and difference method were taken in
comparison studies. Cesium (Cs) and Rubidium (Rb) nanoparticles in
PMF were detected by Energy Dispersive X-ray attached to Scanning
Electron Microscope SEM-EDX. Characteristic changes in protein
secondary structure, lipid profile and changes in the intensities of
DNA bands were identified in treated A549 cells spectra. A
characteristic internucleosomal ladder of DNA fragmentation was
also observed after 30 min of treatment. Moreover, the pH values
were significantly increases upon treatment due to the presence of Cs
and Rb nanoparticles in the PMF fraction. These results support the
previous findings that PMF is selective anticancer agent and can
produce apoptosis to A549 cells.
Abstract: Software developed for a specific customer under contract
typically undergoes a period of testing by the customer before
acceptance. This is known as user acceptance testing and the process
can reveal both defects in the system and requests for changes to
the product. This paper uses nonhomogeneous Poisson processes to
model a real user acceptance data set from a recently developed
system. In particular a split Poisson process is shown to provide an
excellent fit to the data. The paper explains how this model can be
used to aid the allocation of resources through the accurate prediction
of occurrences both during the acceptance testing phase and before
this activity begins.
Abstract: Cerium-doped lanthanum bromide LaBr3:Ce(5%)
crystals are considered to be one of the most advanced scintillator
materials used in PET scanning, combining a high light yield, fast
decay time and excellent energy resolution. Apart from the correct
choice of scintillator, it is also important to optimise the detector
geometry, not least in terms of source-to-detector distance in order to
obtain reliable measurements and efficiency. In this study a
commercially available 25 mm x 25 mm BrilLanCeTM 380 LaBr3: Ce
(5%) detector was characterised in terms of its efficiency at varying
source-to-detector distances. Gamma-ray spectra of 22Na, 60Co, and
137Cs were separately acquired at distances of 5, 10, 15, and 20cm. As
a result of the change in solid angle subtended by the detector, the
geometric efficiency reduced in efficiency with increasing distance.
High efficiencies at low distances can cause pulse pile-up when
subsequent photons are detected before previously detected events
have decayed. To reduce this systematic error the source-to-detector
distance should be balanced between efficiency and pulse pile-up
suppression as otherwise pile-up corrections would need to be
necessary at short distances. In addition to the experimental
measurements Monte Carlo simulations have been carried out for the
same setup, allowing a comparison of results. The advantages and
disadvantages of each approach have been highlighted.
Abstract: An efficient architecture for low jitter All Digital
Phase Locked Loop (ADPLL) suitable for high speed SoC
applications is presented in this paper. The ADPLL is designed using
standard cells and described by Hardware Description Language
(HDL). The ADPLL implemented in a 90 nm CMOS process can
operate from 10 to 200 MHz and achieve worst case frequency
acquisition in 14 reference clock cycles. The simulation result shows
that PLL has cycle to cycle jitter of 164 ps and period jitter of 100 ps
at 100MHz. Since the digitally controlled oscillator (DCO) can
achieve both high resolution and wide frequency range, it can meet
the demands of system-level integration. The proposed ADPLL can
easily be ported to different processes in a short time. Thus, it can
reduce the design time and design complexity of the ADPLL, making
it very suitable for System-on-Chip (SoC) applications.
Abstract: There are two common methodologies to verify
signatures: the functional approach and the parametric approach. This
paper presents a new approach for dynamic handwritten signature
verification (HSV) using the Neural Network with verification by the
Conjugate Gradient Neural Network (NN). It is yet another avenue in
the approach to HSV that is found to produce excellent results when
compared with other methods of dynamic. Experimental results show
the system is insensitive to the order of base-classifiers and gets a
high verification ratio.
Abstract: Bones are dynamic and responsive organs, they
regulate their strength and mass according to the loads which they are subjected. Because, the Wnt/β-catenin pathway has profound
effects on the regulation of bone mass, we hypothesized that mechanical loading of bone cells stimulates Wnt/β-catenin signaling, which results in the generation of new bone mass.
Mechanical loading triggers the secretion of the Wnt molecule, which after binding to transmembrane proteins, causes GSK-3β (Glycogen synthase kinase 3 beta) to cease the phosphorylation of β-catenin. β-catenin accumulation in the cytoplasm, followed by its
transport into the nucleus, binding to transcription factors (TCF/LEF)
that initiate transcription of genes related to bone formation. To test this hypothesis, we used TOPGAL (Tcf Optimal Promoter
β-galactosidase) mice in an experiment in which cyclic loads were
applied to the forearm. TOPGAL mice are reporters for cells effected
by the Wnt/β-catenin signaling pathway. TOPGAL mice are genetically engineered mice in which transcriptional activation of β-
catenin, results in the production of an enzyme, β-galactosidase. The
presence of this enzyme allows us to localize transcriptional
activation of β-catenin to individual cells, thereby, allowing us to quantify the effects that mechanical loading has on the Wnt/β-catenin pathway and new bone formation. The ulnae of loaded TOPGAL
mice were excised and transverse slices along different parts of the
ulnar shaft were assayed for the presence of β-galactosidase.
Our results indicate that loading increases β-catenin transcriptional
activity in regions where this pathway is already primed (i.e. where basal activity is already higher) in a load magnitude dependent
manner. Further experiments are needed to determine the temporal and spatial activation of this signaling in relation to bone formation.
Abstract: The possibility of using cassava residue containing
49.66% starch, 21.47% cellulose, 12.97% hemicellulose, and 21.86%
lignin as a raw material to produce glucose using enzymatic
hydrolysis was investigated. In the experiment, each reactor
contained the cassava residue, bacteria cells, and production medium.
The effects of particles size (40 mesh and 60 mesh) and strains of
bacteria (A002 and M015) isolated from Thai higher termites,
Microcerotermes sp., on the glucose concentration at 37°C were
focused. High performance liquid chromatography (HPLC) with a
refractive index detector was used to determine the quantity of
glucose. The maximum glucose concentration obtained at 37°C using
strain A002 and 60 mesh of the cassava residue was 1.51 g/L at 10 h.
Abstract: The study in this paper underlines the importance of
correct joint selection of the spreading codes for uplink of multicarrier
code division multiple access (MC-CDMA) at the transmitter
side and detector at the receiver side in the presence of nonlinear
distortion due to high power amplifier (HPA). The bit error rate
(BER) of system for different spreading sequences (Walsh code, Gold
code, orthogonal Gold code, Golay code and Zadoff-Chu code) and
different kinds of receivers (minimum mean-square error receiver
(MMSE-MUD) and microstatistic multi-user receiver (MSF-MUD))
is compared by means of simulations for MC-CDMA transmission
system. Finally, the results of analysis will show, that the application
of MSF-MUD in combination with Golay codes can outperform
significantly the other tested spreading codes and receivers for all
mostly used models of HPA.
Abstract: This work consists of three parts. First, the alias-free
condition for the conventional two-channel quadrature mirror filter
bank is analyzed using complex arithmetic. Second, the approach
developed in the first part is applied to the complex quadrature mirror
filter bank. Accordingly, the structure is simplified and the theory is
easier to follow. Finally, a new class of complex quadrature mirror
filter banks is proposed. Interesting properties of this new structure
are also discussed.
Abstract: In this paper, we have proposed a Haar wavelet quasilinearization
method to solve the well known Blasius equation. The
method is based on the uniform Haar wavelet operational matrix
defined over the interval [0, 1]. In this method, we have proposed the
transformation for converting the problem on a fixed computational
domain. The Blasius equation arises in the various boundary layer
problems of hydrodynamics and in fluid mechanics of laminar
viscous flows. Quasi-linearization is iterative process but our
proposed technique gives excellent numerical results with quasilinearization
for solving nonlinear differential equations without any
iteration on selecting collocation points by Haar wavelets. We have
solved Blasius equation for 1≤α ≤ 2 and the numerical results are
compared with the available results in literature. Finally, we
conclude that proposed method is a promising tool for solving the
well known nonlinear Blasius equation.
Abstract: This paper presents the use of anti-sway angle control
approaches for a two-dimensional gantry crane with disturbances
effect in the dynamic system. Delayed feedback signal (DFS) and
proportional-derivative (PD)-type fuzzy logic controller are the
techniques used in this investigation to actively control the sway
angle of the rope of gantry crane system. A nonlinear overhead
gantry crane system is considered and the dynamic model of the
system is derived using the Euler-Lagrange formulation. A complete
analysis of simulation results for each technique is presented in time
domain and frequency domain respectively. Performances of both
controllers are examined in terms of sway angle suppression and
disturbances cancellation. Finally, a comparative assessment of the
impact of each controller on the system performance is presented and
discussed.
Abstract: In the past years, the world has witnessed significant work in the field of Manufacturing. Special efforts have been made in the implementation of new technologies, management and control systems, among many others which have all evolved the field. Closely following all this, due to the scope of new projects and the need of turning the existing flexible ideas into more autonomous and intelligent ones, i.e.: moving toward a more intelligent manufacturing, the present paper emerges with the main aim of contributing to the analysis and a few customization issues of a new iCIM 3000 system at the IPSAM. In this process, special emphasis in made on the material flow problem. For this, besides offering a description and analysis of the system and its main parts, also some tips on how to define other possible alternative material flow scenarios and a partial analysis of the combinatorial nature of the problem are offered as well. All this is done with the intentions of relating it with the use of simulation tools, for which these have been briefly addressed with a special focus on the Witness simulation package. For a better comprehension, the previous elements are supported by a few figures and expressions which would help obtaining necessary data. Such data and others will be used in the future, when simulating the scenarios in the search of the best material flow configurations.
Abstract: Lately, significant work in the area of Intelligent
Manufacturing has become public and mainly applied within the
frame of industrial purposes. Special efforts have been made in the
implementation of new technologies, management and control
systems, among many others which have all evolved the field. Aware
of all this and due to the scope of new projects and the need of
turning the existing flexible ideas into more autonomous and
intelligent ones, i.e.: Intelligent Manufacturing, the present paper
emerges with the main aim of contributing to the design and analysis
of the material flow in either systems, cells or work stations under
this new “intelligent" denomination. For this, besides offering a
conceptual basis in some of the key points to be taken into account
and some general principles to consider in the design and analysis of
the material flow, also some tips on how to define other possible
alternative material flow scenarios and a classification of the states a
system, cell or workstation are offered as well. All this is done with
the intentions of relating it with the use of simulation tools, for which
these have been briefly addressed with a special focus on the Witness
simulation package. For a better comprehension, the previous
elements are supported by a detailed layout, other figures and a few
expressions which could help obtaining necessary data. Such data and
others will be used in the future, when simulating the scenarios in the
search of the best material flow configurations.
Abstract: The objective of this research is to study of microbial lipid production by locally photosynthetic microalgae and oleaginous yeast via integrated cultivation technique using CO2 emissions from yeast fermentation. A maximum specific growth rate of Chlorella sp. KKU-S2 of 0.284 (1/d) was obtained under an integrated cultivation and a maximum lipid yield of 1.339g/L was found after cultivation for 5 days, while 0.969g/L of lipid yield was obtained after day 6 of cultivation time by using CO2 from air. A high value of volumetric lipid production rate (QP, 0.223 g/L/d), specific product yield (YP/X, 0.194), volumetric cell mass production rate (QX, 1.153 g/L/d) were found by using ambient air CO2 coupled with CO2 emissions from yeast fermentation. Overall lipid yield of 8.33 g/L was obtained (1.339 g/L of Chlorella sp. KKU-S2 and 7.06g/L of T. maleeae Y30) while low lipid yield of 0.969g/L was found using non-integrated cultivation technique. To our knowledge this is the unique report about the lipid production from locally microalgae Chlorella sp. KKU-S2 and yeast T. maleeae Y30 in an integrated technique to improve the biomass and lipid yield by using CO2 emissions from yeast fermentation.
Abstract: In this paper, we consider the problem of logic simplification for a special class of logic functions, namely complementary Boolean functions (CBF), targeting low power implementation using static CMOS logic style. The functions are uniquely characterized by the presence of terms, where for a canonical binary 2-tuple, D(mj) ∪ D(mk) = { } and therefore, we have | D(mj) ∪ D(mk) | = 0 [19]. Similarly, D(Mj) ∪ D(Mk) = { } and hence | D(Mj) ∪ D(Mk) | = 0. Here, 'mk' and 'Mk' represent a minterm and maxterm respectively. We compare the circuits minimized with our proposed method with those corresponding to factored Reed-Muller (f-RM) form, factored Pseudo Kronecker Reed-Muller (f-PKRM) form, and factored Generalized Reed-Muller (f-GRM) form. We have opted for algebraic factorization of the Reed-Muller (RM) form and its different variants, using the factorization rules of [1], as it is simple and requires much less CPU execution time compared to Boolean factorization operations. This technique has enabled us to greatly reduce the literal count as well as the gate count needed for such RM realizations, which are generally prone to consuming more cells and subsequently more power consumption. However, this leads to a drawback in terms of the design-for-test attribute associated with the various RM forms. Though we still preserve the definition of those forms viz. realizing such functionality with only select types of logic gates (AND gate and XOR gate), the structural integrity of the logic levels is not preserved. This would consequently alter the testability properties of such circuits i.e. it may increase/decrease/maintain the same number of test input vectors needed for their exhaustive testability, subsequently affecting their generalized test vector computation. We do not consider the issue of design-for-testability here, but, instead focus on the power consumption of the final logic implementation, after realization with a conventional CMOS process technology (0.35 micron TSMC process). The quality of the resulting circuits evaluated on the basis of an established cost metric viz., power consumption, demonstrate average savings by 26.79% for the samples considered in this work, besides reduction in number of gates and input literals by 39.66% and 12.98% respectively, in comparison with other factored RM forms.
Abstract: In the present work we report a gram negative
bacterial isolate, from soil of a dye industry, with promising
biorefining and bioremediation potential. This isolate (GBS.5) could
utilize carbazole (nitrogen containing polycyclic aromatic
hydrocarbon) as the sole source of nitrogen and carbon and utilize
almost 98% of 3mM carbazole in 100 hours. The specific activity of
our GBS.5 isolate for carbazole degradation at 30°C and pH 7.0 was
found to be 11.36 μmol/min/g dry cell weight as compared to 10.4
μmol/min/g dry cell weight, the highest reported specific activity till
date. The presence of car genes (the genes involved in
denitrogenation of carbazole) was confirmed through PCR
amplification.
Abstract: This study determines the effect of naked and heparinbased
super-paramagnetic iron oxide nanoparticles on the human
cancer cell lines of A2780. Doxorubicin was used as the anticancer
drug, entrapped in the SPIO-NPs. This study aimed to decorate
nanoparticles with heparin, a molecular ligand for 'active' targeting
of cancerous cells and the application of modified-nanoparticles in
cancer treatment. The nanoparticles containing the anticancer drug
DOX were prepared by a solvent evaporation and emulsification
cross-linking method. The physicochemical properties of the
nanoparticles were characterized by various techniques, and uniform
nanoparticles with an average particle size of 110±15 nm with high
encapsulation efficiencies (EE) were obtained. Additionally, a
sustained release of DOX from the SPIO-NPs was successful.
Cytotoxicity tests showed that the SPIO-DOX-HP had higher cell
toxicity than the individual HP and confocal microscopy analysis
confirmed excellent cellular uptake efficiency. These results indicate
that HP based SPIO-NPs have potential uses as anticancer drug
carriers and also have an enhanced anticancer effect.