Abstract: Tumour suppressors are key participants in the
prevention of cancer. Regulation of their expression through
miRNAs is important for comprehensive translation inhibition of
tumour suppressors and elucidation of carcinogenesis mechanisms.
We studies the possibility of 1521 miRNAs to bind with 873 mRNAs
of human tumour suppressors using RNAHybrid 2.1 and ERNAhybrid
programmes. Only 978 miRNAs were found to be
translational regulators of 812 mRNAs, and 61 mRNAs did not have
any miRNA binding sites. Additionally, 45.9% of all miRNA binding
sites were located in coding sequences (CDSs), 33.8% were located
in 3' untranslated region (UTR), and 20.3% were located in the
5'UTR. MiRNAs binding with more than 50 target mRNAs and
mRNAs binding with several miRNAs were selected. Hsa-miR-5096
had 15 perfectly complementary binding sites with mRNAs of 14
tumour suppressors. These newly indentified miRNA binding sites
can be used in the development of medicines (anti-sense therapies)
for cancer treatment.
Abstract: By using Mawhin-s continuation theorem of coincidence degree theory, we establish the existence of 2n positive periodic solutions for n species non-autonomous Lotka-Volterra competition systems with harvesting terms. An example is given to illustrate the effectiveness of our results.
Abstract: This paper describes the challenges on the requirements engineering for developing an enterprise applications in higher
education environment. The development activities include software implementation, maintenance, and enhancement and support for online
transaction processing and overnight batch processing.
Generally, an enterprise application for higher education environment
may include Student Information System (SIS), HR/Payroll system,
Financial Systems etc. By the way, there are so many challenges in
requirement engineering phases in order to provide two distinctive
services that are production processing support and systems
development.
Abstract: An actual power plant, which is the power plant of Iron and Steel Factory at Misurata city in Libya , has been modeled using Matlab in order to compare its results to the actual results of the actual cycle. This paper concentrates on two factors:
a- The comparison between exergy losses in the actual cycle and the modeled cycle.
b- The effect of extracting pressure on temperature water at boiler inlet.
Closed heat exchangers used in this plant have been substituted by open heat exchangers in the current study of the modeled power plant and the required changes in the pressure have been considered. In the following investigation the two points mentioned above are taken in consideration.
Abstract: Since large power transformers are the most
expensive and strategically important components of any power
generator and transmission system, their reliability is crucially
important for the energy system operation. Also, Circuit breakers are
very important elements in the power transmission line so monitoring
the events gives a knowledgebase to determine time to the next
maintenance. This paper deals with the introduction of the
comparative method of the state estimation of transformers and
Circuit breakers using continuous monitoring of voltage, current.
This paper gives details a new method based on wavelet to apparatus
insulation monitoring. In this paper to insulation monitoring of
transformer, a new method based on wavelet transformation and
neutral point analysis is proposed. Using the EMTP tools, fault in
transformer winding and the detailed transformer winding model
were simulated. The current of neutral point of winding was analyzed
by wavelet transformation. It is shown that the neutral current of the
transformer winding has useful information about fault in insulation
of the transformer.
Abstract: Fuzzy linear programming is an application of fuzzy set theory in linear decision making problems and most of these problems are related to linear programming with fuzzy variables. A convenient method for solving these problems is based on using of auxiliary problem. In this paper a new method for solving fuzzy variable linear programming problems directly using linear ranking functions is proposed. This method uses simplex tableau which is used for solving linear programming problems in crisp environment before.
Abstract: Intradiscal and intervertebral pressure transducers
were developed. They were used to map the pressures in the nucleus
and within the annulus of the human spinal segments. Their stressrelaxation
were recorded over a period of time for nucleus
pressure, applied load, and peripherial strain against time. The
results show that for normal discs, pressures in the nucleus are
viscoelastic in nature with the applied compressive load.
Mechanical strains which develop around the periphery of the
vertebral body are also viscoelastic with the applied compressive
load. Applied compressive load against time also shows viscoelastic
behavior. However, annulus does not respond viscoelastically with
the applied load. It showed a linear response to compressive loading.
Abstract: The Informational Infrastructures of small and medium-sized manufacturing enterprises are relatively poor, there are serious shortages of capitals which can be invested in informatization construction, computer hardware and software resources, and human resources. To address the informatization issue in small and medium-sized manufacturing enterprises, and enable them to the application of advanced management thinking and enhance their competitiveness, the paper establish a manufacturing-oriented small and medium-sized enterprises informatization platform based on the ASP business intelligence technology, which effectively improves the scientificity of enterprises decision and management informatization.
Abstract: A novel concept to balance and tradeoff between
make-to-stock and make-to-order has been hybrid MTS/MTO production context. One of the most important decisions involved in
the hybrid MTS/MTO environment is determining whether a product
is manufactured to stock, to order, or hybrid MTS/MTO strategy. In this paper, a model based on analytic network process is developed to tackle the addressed decision. Since the regarded decision deals with
the uncertainty and ambiguity of data as well as experts- and
managers- linguistic judgments, the proposed model is equipped with
fuzzy sets theory. An important attribute of the model is its generality due to diverse decision factors which are elicited from the
literature and developed by the authors. Finally, the model is validated by applying to a real case study to reveal how the proposed
model can actually be implemented.
Abstract: A spanning tree of a connected graph is a tree which
consists the set of vertices and some or perhaps all of the edges from
the connected graph. In this paper, a model for spanning tree
transformation of connected graphs into single-row networks, namely
Spanning Tree of Connected Graph Modeling (STCGM) will be
introduced. Path-Growing Tree-Forming algorithm applied with
Vertex-Prioritized is contained in the model to produce the spanning
tree from the connected graph. Paths are produced by Path-Growing
and they are combined into a spanning tree by Tree-Forming. The
spanning tree that is produced from the connected graph is then
transformed into single-row network using Tree Sequence Modeling
(TSM). Finally, the single-row routing problem is solved using a
method called Enhanced Simulated Annealing for Single-Row
Routing (ESSR).
Abstract: Among all geo-hydrological relationships, rainfallrunoff
relationship is of utmost importance in any hydrological
investigation and water resource planning. Spatial variation, lag time
involved in obtaining areal estimates for the basin as a whole can
affect the parameterization in design stage as well as in planning
stage. In conventional hydrological processing of data, spatial aspect
is either ignored or interpolated at sub-basin level. Temporal
variation when analysed for different stages can provide clues for its
spatial effectiveness. The interplay of space-time variation at pixel
level can provide better understanding of basin parameters.
Sustenance of design structures for different return periods and their
spatial auto-correlations should be studied at different geographical
scales for better management and planning of water resources.
In order to understand the relative effect of spatio-temporal
variation in hydrological data network, a detailed geo-hydrological
analysis of Betwa river catchment falling in Lower Yamuna Basin is
presented in this paper. Moreover, the exact estimates about the
availability of water in the Betwa river catchment, especially in the
wake of recent Betwa-Ken linkage project, need thorough scientific
investigation for better planning. Therefore, an attempt in this
direction is made here to analyse the existing hydrological and
meteorological data with the help of SPSS, GIS and MS-EXCEL
software. A comparison of spatial and temporal correlations at subcatchment
level in case of upper Betwa reaches has been made to
demonstrate the representativeness of rain gauges. First, flows at
different locations are used to derive correlation and regression
coefficients. Then, long-term normal water yield estimates based on
pixel-wise regression coefficients of rainfall-runoff relationship have
been mapped. The areal values obtained from these maps can
definitely improve upon estimates based on point-based
extrapolations or areal interpolations.
Abstract: A new observer based fault detection and diagnosis
scheme for predicting induction motors- faults is proposed in this
paper. Prediction of incipient faults, using different variants of
Kalman filter and their relative performance are evaluated. Only soft
faults are considered for this work. The data generation, filter
convergence issues, hypothesis testing and residue estimates are
addressed. Simulink model is used for data generation and various
types of faults are considered. A comparative assessment of the
estimates of different observers associated with these faults is
included.
Abstract: The higher compounded growth rates coupled with
favourable demographics in emerging markets portend abundant
opportunities for multinational organizations. With many
organizations competing for talent in these growing markets, their
ability to succeed will depend on their understanding of local
workforce needs and aspirations. Using data from the Towers Watson
2010 Global Workforce Study, this paper highlights differences in
employee engagement, turnover risks, and attraction and retention
drivers between the two markets. Apart from looking at the
traditional drivers of employee engagement, the study also explores
the value placed by employees on elements like a strong senior
leadership, managerial capabilities and career advancement
opportunities. Results reveal that emerging markets employees seem
to be more engaged and value the non-traditional elements more
highly than the developed markets employees.
Abstract: Heavy rainfall greatly affects the aerodynamic performance of the aircraft. There are many accidents of aircraft caused by aerodynamic efficiency degradation by heavy rain.
In this Paper we have studied the heavy rain effects on the aerodynamic efficiency of cambered NACA 64-210 and symmetric
NACA 0012 airfoils. Our results show significant increase in drag and decrease in lift. We used preprocessing software gridgen for creation of geometry and mesh, used fluent as solver and techplot as postprocessor. Discrete phase modeling called DPM is used to model the rain particles using two phase flow approach. The rain particles are assumed to be inert.
Both airfoils showed significant decrease in lift and increase in drag in simulated rain environment. The most significant difference between these two airfoils was the NACA 64-210 more sensitivity than NACA 0012 to liquid water content (LWC). We believe that the results showed in this paper will be useful for the designer of the commercial aircrafts and UAVs, and will be helpful for training of the pilots to control the airplanes in heavy rain.
Abstract: The Kowsar dam supply water for different usages
such as drinking, industrial, agricultural and aquaculture farms
usages and located next to the city of Dehdashat in Kohgiluye and
Boyerahmad province in southern Iran. There are some towns and
villages on the Kowsar dam watersheds, which Dehdasht and Choram
are the most important and populated cities in this area. The study
was undertaken to assess the status of water quality in the urban areas
of the Kowsar dam. A total of 28 water samples were collected from
6 stations on surface water and 1 station from groundwater on the
watershed of the Kowsar dam. All the samples were analyzed for Ni
concentration using standard procedures. The results were compared
with other national and international standards. Among the analyzed
samples, as the maximum value of Nickel (0.01 mg/L) was observed
on the station 2 at the autumn 2010, all the samples analyzed were
within the maximum admissible limits by the United States
Environmental Protection Agency, EU, WHO and the Iranian. In
general results of the present study have shown that a Ni mean value
of station No. 2 with 0.006 mg/L is higher than the other stations. Ni
level of all samples and stations have had normal values and this is an
indication of pollution potential and hazards because of human
activity and waste water of towns in the areas, which can effect on
human health implications in future. This research, therefore,
recommends the government and other responsible authorities to take
suitable improving measures in the Kowsar dam watersheds.
Abstract: The article examines an opportunity of corruption
restriction exercised by international business community in Russia.
Integration of Russian economy into the international business does
not reduce corruption inside the country. Foreign actors investing in
Russia under the condition of obtaining their required rates of returns
will be reluctant to harm their investments by involving into anticorruption
activities. Furthermore, many Russian firms- competitive
advantage could be directly related to their corruption connections. In
this case, foreign investments would only accentuate corrupt
companies- success by supporting them financially
Abstract: Nano MgO has been synthesized by hydration and
dehydration method by modifies the commercial MgO. The prepared
MgO had been investigated as a heterogeneous base catalyst for
transesterification process for biodiesel production using palm oil.
TGA, FT-IR and XRD results obtained from this study lie each other
and proved in the formation of nano MgO from decomposition of
Mg(OH)2. This study proved that the prepared nano MgO was a
better base transesterification catalyst compared to commercial MgO.
The nano MgO calcined at 600ºC had gives the highest conversion of
51.3% of palm oil to biodiesel.
Abstract: In a state-of-the-art industrial production line of
photovoltaic products the handling and automation processes are of
particular importance and implication. While processing a fully
functional crystalline solar cell an as-cut photovoltaic wafer is subject
to numerous repeated handling steps. With respect to stronger
requirements in productivity and decreasing rejections due to defects
the mechanical stress on the thin wafers has to be reduced to a
minimum as the fragility increases by decreasing wafer thicknesses.
In relation to the increasing wafer fragility, researches at the
Fraunhofer Institutes IPA and CSP showed a negative correlation
between multiple handling processes and the wafer integrity. Recent
work therefore focused on the analysis and optimization of the dry
wafer stack separation process with compressed air. The achievement
of a wafer sensitive process capability and a high production
throughput rate is the basic motivation in this research.
Abstract: Methanol-to-olefins (MTO) coupled with
transformation of coal or natural gas to methanol gives an interesting
and promising way to produce ethylene and propylene. To investigate
solid concentration in gas-solid fluidized bed for methanol-to-olefins
process catalyzed by SAPO-34, a cold model experiment system is
established in this paper. The system comprises a gas distributor in a
300mm internal diameter and 5000mm height acrylic column, the
fiber optic probe system and series of cyclones. The experiments are
carried out at ambient conditions and under different superficial gas
velocity ranging from 0.3930m/s to 0.7860m/s and different initial bed
height ranging from 600mm to 1200mm. The effects of radial
distance, axial distance, superficial gas velocity, initial bed height on
solid concentration in the bed are discussed. The effects of distributor
shape and porosity on solid concentration are also discussed. The
time-averaged solid concentration profiles under different conditions
are obtained.
Abstract: In aerospace applications, interactions of airflow with
aircraft structures can result in undesirable structural deformations.
This structural deformation in turn, can be predicted if the natural
modes of the structure are known. This can be achieved through
conventional modal testing that requires a known excitation force in
order to extract these dynamic properties. This technique can be
experimentally complex because of the need for artificial excitation
and it is also does not represent actual operational condition. The
current work presents part of research work that address the practical
implementation of operational modal analysis (OMA) applied to a
cantilevered hybrid composite plate employing single contactless
sensing system via laser vibrometer. OMA technique extracts the
modal parameters based only on the measurements of the dynamic
response. The OMA results were verified with impact hammer modal
testing and good agreement was obtained.