Abstract: Shadoo protein (Sho) was described in 2003 as the newest member of Prion protein superfamily [1]. Sho has similar structural motifs like prion protein (PrP) that is known for its central role in transmissible spongiform enchephalopathies. Although a great number of functions have been proposed, the exact physiological function of PrP is not known yet. Investigation of the function and localization of Sho may help us to understand the function of the Prion protein superfamily. Analyzing the subcellular localization of YFP-tagged forms of Sho, we detected the protein in the plasma membrane and in the nucleus of various cell lines. To reveal the localization of the endogenous protein we generated antibodies against Shadoo as well as employed commercially available anti-Shadoo antibodies: i) EG62 anti-mouse Shadoo antibody generated by Eurogentec Ltd.; ii) S-12 anti-human Shadoo antibody by Santa Cruz Biotechnology Inc.; iii) R-12 anti-mouse Shadoo antibody by Santa Cruz Biotechnology Inc.; iv) SPRN antibody against human Shadoo by Abgent Inc. We carried out immunocytochemistry on non-transfected HeLa, Zpl 2-1, Zw 3-5, GT1-1, GT1-7 and SHSY5Y cells as well as on YFP-Sho, Sho-YFP, and YFP-GPI transfected HeLa cells. Their specificity (in antibody-peptide competition assay) and co-localization (with the YFP signal) were assessed.
Abstract: Along with the advances in medicine, providing medical information to individual patient is becoming more important. In Japan such information via Braille is hardly provided to blind and partially sighted people. Thus we are researching and developing a Web-based automatic translation program “eBraille" to translate Japanese text into Japanese Braille. First we analyzed the Japanese transcription rules to implement them on our program. We then added medical words to the dictionary of the program to improve its translation accuracy for medical text. Finally we examined the efficacy of statistical learning models (SLMs) for further increase of word segmentation accuracy in braille translation. As a result, eBraille had the highest translation accuracy in the comparison with other translation programs, improved the accuracy for medical text and is utilized to make hospital brochures in braille for outpatients and inpatients.
Abstract: Previous studies have shown that there are arguments
regarding the reliability and validity of the Ashworth and Modified
Ashworth Scale towards evaluating patients diagnosed with upper
limb disorders. These evaluations depended on the raters’ experiences.
This initiated us to develop an upper limb disorder part-task trainer
that is able to simulate consistent upper limb disorders, such as
spasticity and rigidity signs, based on the Modified Ashworth Scale to
improve the variability occurring between raters and intra-raters
themselves. By providing consistent signs, novice therapists would be
able to increase training frequency and exposure towards various
levels of signs. A total of 22 physiotherapists and occupational
therapists participated in the study. The majority of the therapists
agreed that with current therapy education, they still face problems
with inter-raters and intra-raters variability (strongly agree 54%; n =
12/22, agree 27%; n = 6/22) in evaluating patients’ conditions. The
therapists strongly agreed (72%; n = 16/22) that therapy trainees
needed to increase their frequency of training; therefore believe that
our initiative to develop an upper limb disorder training tool will help
in improving the clinical education field (strongly agree and agree
63%; n = 14/22).
Abstract: Compare to western cultures, women who smoke in Korea are not tolerated. Korean people are prejudiced against women smoking. In spite of the relative prevalence of sexual equality in South Korea, women too often feel obliged to confine their smoking to only a few public spaces, such as designated smoking rooms, coffee shops or pubs. Korean Confucianism classifies people according to gender and social status. According to Confucian culture, cigarettes convey clear social meanings as well as reinforcing status, age and gender, beyond personal preferences. For these reasons, the significant of people smoking in Korea varies according to their gender. This study will determine reasons for the ongoing sexual discrimination against female Korean smokers thorough analyzing Korean films. Since film is a medium reflects social phenomenon. Roland Barthes- Mythology Theory will be used to analyze films.
Abstract: This paper investigated the impact of ceiling height and window head heights variation on daylighting inside architectural teaching studio with a full width window. In architectural education, using the studio is more than normal classroom in most credit hours. Therefore, window position, size and dimension of studio have direct influence on level of daylighting. Daylighting design is a critical factor that improves student learning, concentration and behavior, in addition to these, it also reduces energy consumption. The methodology of analysis involves using Radiance in IES software under overcast and cloudy sky in Malaysia. It has been established that presentation of daylighting of architecture studio can be enhanced by changing the ceiling heights and window level, because, different ceiling heights and window head heights can contribute to different range of daylight levels.
Abstract: Graph coloring is an important problem in computer
science and many algorithms are known for obtaining reasonably
good solutions in polynomial time. One method of comparing
different algorithms is to test them on a set of standard graphs where
the optimal solution is already known. This investigation analyzes a
set of 50 well known graph coloring instances according to a set of
complexity measures. These instances come from a variety of
sources some representing actual applications of graph coloring
(register allocation) and others (mycieleski and leighton graphs) that
are theoretically designed to be difficult to solve. The size of the
graphs ranged from ranged from a low of 11 variables to a high of
864 variables. The method used to solve the coloring problem was
the square of the adjacency (i.e., correlation) matrix. The results
show that the most difficult graphs to solve were the leighton and the
queen graphs. Complexity measures such as density, mobility,
deviation from uniform color class size and number of block
diagonal zeros are calculated for each graph. The results showed that
the most difficult problems have low mobility (in the range of .2-.5)
and relatively little deviation from uniform color class size.
Abstract: This research was to evaluate a technical feasibility of
making single-layer experimental particleboard panels from bamboo
waste (Dendrocalamus asper Backer) by converting bamboo into
strips, which are used to make laminated bamboo furniture. Variable
factors were density (600, 700 and 800 kg/m3) and temperature of
condition (25, 40 and 55 °C). The experimental panels were tested for
their physical and mechanical properties including modulus of
elasticity (MOE), modulus of rupture (MOR), internal bonding
strength (IB), screw holding strength (SH) and thickness swelling
values according to the procedures defined by Japanese Industrial
Standard (JIS). The test result of mechanical properties showed that
the MOR, MOE and IB values were not in the set criteria, except the
MOR values at the density of 700 kg/m3 at 25 °C and at the density
of 800 kg/m3 at 25 and 40 °C, the IB values at the density of 600
kg/m3, at 40 °C, and at the density of 800 kg/m3 at 55 °C. The SH
values had the test result according to the set standard, except with
the density of 600 kg/m3, at 40 and 55 °C. Conclusively, a valuable
renewable biomass, bamboo waste could be used to manufacture
boards.
Abstract: IEEE has designed 802.11i protocol to address the
security issues in wireless local area networks. Formal analysis is
important to ensure that the protocols work properly without having
to resort to tedious testing and debugging which can only show the
presence of errors, never their absence. In this paper, we present
the formal verification of an abstract protocol model of 802.11i.
We translate the 802.11i protocol into the Strand Space Model and
then prove the authentication property of the resulting model using
the Strand Space formalism. The intruder in our model is imbued
with powerful capabilities and repercussions to possible attacks are
evaluated. Our analysis proves that the authentication of 802.11i is
not compromised in the presented model. We further demonstrate
how changes in our model will yield a successful man-in-the-middle
attack.
Abstract: Lately, an interest has grown greatly in the usages of
RFID in an un-presidential applications. It is shown in the adaptation
of major software companies such as Microsoft, IBM, and Oracle
the RFID capabilities in their major software products. For example
Microsoft SharePoints 2010 workflow is now fully compatible with
RFID platform. In addition, Microsoft BizTalk server is also capable
of all RFID sensors data acquisition. This will lead to applications
that required high bit rate, long range and a multimedia content in
nature. Higher frequencies of operation have been designated for
RFID tags, among them are the 2.45 and 5.8 GHz. The higher the
frequency means higher range, and higher bit rate, but the drawback
is the greater cost. In this paper we present a single layer, low
profile patch antenna operates at 5.8 GHz with pure resistive input
impedance of 50 and close to directive radiation. Also, we propose
a modification to the design in order to improve the operation band
width from 8.7 to 13.8
Abstract: The study investigated the practices of organisations in Gulf Cooperation Council (GCC) countries with regards to G2C egovernment maturity. It reveals that e-government G2C initiatives in the surveyed countries in particular, and arguably around the world in general, are progressing slowly because of the lack of a trusted and secure medium to authenticate the identities of online users. The authors conclude that national ID schemes will play a major role in helping governments reap the benefits of e-government if the three advanced technologies of smart card, biometrics and public key infrastructure (PKI) are utilised to provide a reliable and trusted authentication medium for e-government services.
Abstract: This paper deals with wireless relay communication
systems in which multiple sources transmit information to the
destination node by the help of multiple relays. We consider a
signal forwarding technique based on the minimum mean-square
error (MMSE) approach with multiple antennas for each relay. A
source-relay-destination joint design strategy is proposed with power
constraints at the destination and the source nodes. Simulation results
confirm that the proposed joint design method improves the average
MSE performance compared with that of conventional MMSE relaying
schemes.
Abstract: The paper depicts air velocity values, reproduced by laser Doppler anemometer (LDA) and ultrasonic anemometer (UA), relations with calculated ones from flow rate measurements using the gas meter which calibration uncertainty is ± (0.15 – 0.30) %. Investigation had been performed in channel installed in aerodynamical facility used as a part of national standard of air velocity. Relations defined in a research let us confirm the LDA and UA for air velocity reproduction to be the most advantageous measures. The results affirm ultrasonic anemometer to be reliable and favourable instrument for measurement of mean velocity or control of velocity stability in the velocity range of 0.05 m/s – 10 (15) m/s when the LDA used. The main aim of this research is to investigate low velocity regularities, starting from 0.05 m/s, including region of turbulent, laminar and transitional air flows. Theoretical and experimental results and brief analysis of it are given in the paper. Maximum and mean velocity relations for transitional air flow having unique distribution are represented. Transitional flow having distinctive and different from laminar and turbulent flow characteristics experimentally have not yet been analysed.
Abstract: Hemorrhage Disease of Grass Carp (HDGC) is a kind
of commonly occurring illnesses in summer, and the extremely high
death rate result in colossal losses to aquaculture. As the complex
connections among each factor which influences aquiculture diseases,
there-s no quit reasonable mathematical model to solve the problem at
present.A BP neural network which with excellent nonlinear mapping
coherence was adopted to establish mathematical model;
Environmental factor, which can easily detected, such as breeding
density, water temperature, pH and light intensity was set as the main
analyzing object. 25 groups of experimental data were used for
training and test, and the accuracy of using the model to predict the
trend of HDGC was above 80%. It is demonstrated that BP neural
network for predicating diseases in HDGC has a particularly
objectivity and practicality, thus it can be spread to other aquiculture
disease.
Abstract: In this paper we develop an efficient numerical method for the finite-element model updating of damped gyroscopic systems based on incomplete complex modal measured data. It is assumed that the analytical mass and stiffness matrices are correct and only the damping and gyroscopic matrices need to be updated. By solving a constrained optimization problem, the optimal corrected symmetric damping matrix and skew-symmetric gyroscopic matrix complied with the required eigenvalue equation are found under a weighted Frobenius norm sense.
Abstract: This experiment was carried out to study the effect of
AMF, drought stress and phosphorus on physiological growth indices of basil at Iran using by a split-plot design with three replications.
The main-plot factor included: two levels of irrigation regimes (control=no drought stress and irrigation after 80 evaporation=
drought stress condition) while the sub-plot factors included
phosphorus (0, 35 and 70 kg/ha) and application and non-application of Glomus fasciculatum. The results showed that total dry matter
(TDM), life area index (LAI), relative growth rate (RGR) and crop growth rate (CGR) were all highly significantly different among the
phosphorus, whereas drought stress had effect of practical
significance on TDM, LAI, RGR and CGR. The results also showed that the highest TDM, LAI, RGR and CGR were obtained from
application of Glomus fasciculatum under no-drought condition.
Abstract: There have been various methods created based on the regression ideas to resolve the problem of data set containing censored observations, i.e. the Buckley-James method, Miller-s method, Cox method, and Koul-Susarla-Van Ryzin estimators. Even though comparison studies show the Buckley-James method performs better than some other methods, it is still rarely used by researchers mainly because of the limited diagnostics analysis developed for the Buckley-James method thus far. Therefore, a diagnostic tool for the Buckley-James method is proposed in this paper. It is called the renovated Cook-s Distance, (RD* i ) and has been developed based on the Cook-s idea. The renovated Cook-s Distance (RD* i ) has advantages (depending on the analyst demand) over (i) the change in the fitted value for a single case, DFIT* i as it measures the influence of case i on all n fitted values Yˆ∗ (not just the fitted value for case i as DFIT* i) (ii) the change in the estimate of the coefficient when the ith case is deleted, DBETA* i since DBETA* i corresponds to the number of variables p so it is usually easier to look at a diagnostic measure such as RD* i since information from p variables can be considered simultaneously. Finally, an example using Stanford Heart Transplant data is provided to illustrate the proposed diagnostic tool.
Abstract: In this study, the effects of machining parameters on
specific energy during surface grinding of 6061Al-SiC35P
composites are investigated. Vol% of SiC, feed and depth of cut were
chosen as process variables. The power needed for the calculation of
the specific energy is measured from the two watt meter method.
Experiments are conducted using standard RSM design called Central
composite design (CCD). A second order response surface model was
developed for specific energy. The results identify the significant
influence factors to minimize the specific energy. The confirmation
results demonstrate the practicability and effectiveness of the
proposed approach.
Abstract: This paper proposes an effective adaptation learning
algorithm based on artificial neural networks for speed control of an
induction motor assumed to operate in a high-performance drives
environment. The structure scheme consists of a neural network
controller and an algorithm for changing the NN weights in order that
the motor speed can accurately track of the reference command. This
paper also makes uses a very realistic and practical scheme to
estimate and adaptively learn the noise content in the speed load
torque characteristic of the motor. The availability of the proposed
controller is verified by through a laboratory implementation and
under computation simulations with Matlab-software. The process is
also tested for the tracking property using different types of reference
signals. The performance and robustness of the proposed control
scheme have evaluated under a variety of operating conditions of the
induction motor drives. The obtained results demonstrate the
effectiveness of the proposed control scheme system performances,
both in steady state error in speed and dynamic conditions, was found
to be excellent and those is not overshoot.
Abstract: In modern agriculture, polymeric hydrogels are
known as a component able to hold an amount of water due to their
3-dimensional network structure and their tendency to absorb water
in humid environments. In addition, these hydrogels are able to
controllably release the fertilisers and pesticides loaded in them.
Therefore, they deliver these materials to the plants' roots and help
them with growing. These hydrogels also reduce the pollution of
underground water sources by preventing the active components
from leaching. In this study, sIPN acrylamide based hydrogels are
synthesised by using acrylamide free radical, potassium acrylate, and
linear polyvinyl alcohol. Ammonium nitrate is loaded in the hydrogel
as the fertiliser. The effect of various amounts of monomers and
linear polymer, measured in molar ratio, on the swelling rate,
equilibrium swelling, and release of ammonium nitrate is studied.
Abstract: In the present article, a new method has been developed to enhance the application of equipment monitoring, which in turn results in improving condition-based maintenance economic impact in an automobile parts manufacturing factory. This study also describes how an effective software with a simple database can be utilized to achieve cost-effective improvements in maintenance performance. The most important results of this project are indicated here: 1. 63% reduction in direct and indirect maintenance costs. 2. Creating a proper database to analyse failures. 3. Creating a method to control system performance and develop it to similar systems. 4. Designing a software to analyse database and consequently create technical knowledge to face unusual condition of the system. Moreover, the results of this study have shown that the concept and philosophy of maintenance has not been understood in most Iranian industries. Thus, more investment is strongly required to improve maintenance conditions.