Abstract: Transcription factor p53 has a powerful tumor
suppressing function that is associated with many cancers. However,
p53 of the molecular weight was higher make the limitation across to
skin or cell membrane. Thymidine dinucleotide (pTT), an
oligonucleotide, can activate the p53 transcription factor. pTT is a
hydrophilic and negative charge oligonucleotide, which delivery in to
cell membrane need an appropriate carrier. The aim of this study was
to improve the bioavailability of the nucleotide fragment, thymidine
dinucleotide (pTT), using elasic liposome carriers to deliver the drug
into the skin. The study demonstrate that dioleoylphosphocholine
(DOPC) incorporated with sodium cholate at molar ratio 1:1 can
archived the particle size about 220 nm. This elastic liposome could
penetration through skin from stratum corneum to whole epidermis by
confocal laser scanning microscopy (CLSM). Moreover, we observed
the the slight increase in generation of p53 by western blot.
Abstract: This article describes Uruk, the virtual museum of
Iraq that we developed for visual exploration and retrieval of image
collections. The system largely exploits the loosely-structured
hierarchy of XML documents that provides a useful representation
method to store semi-structured or unstructured data, which does not
easily fit into existing database. The system offers users the
capability to mine and manage the XML-based image collections
through a web-based Graphical User Interface (GUI). Typically, at an
interactive session with the system, the user can browse a visual
structural summary of the XML database in order to select interesting
elements. Using this intermediate result, queries combining structure
and textual references can be composed and presented to the system.
After query evaluation, the full set of answers is presented in a visual
and structured way.
Abstract: The purpose of this paper is to detect human in images.
This paper proposes a method for extracting human body feature descriptors consisting of projected edge component series. The feature descriptor can express appearances and shapes of human with local
and global distribution of edges. Our method evaluated with a linear SVM classifier on Daimler-Chrysler pedestrian dataset, and test with
various sub-region size. The result shows that the accuracy level of
proposed method similar to Histogram of Oriented Gradients(HOG)
feature descriptor and feature extraction process is simple and faster than existing methods.
Abstract: The study of the Andaman Sea can be studied by
using the oceanic model; therefore the grid covering the study area
should be generated. This research aims to generate grid covering
the Andaman Sea, situated between longitudes 90◦E to 101◦E and
latitudes 1◦N to 18◦N. A horizontal grid is an orthogonal curvilinear
with 87 × 217 grid points. The methods used in this study are
cubic spline and bilinear interpolations. The boundary grid points
are generated by spline interpolation while the interior grid points
have to be specified by bilinear interpolation method. A vertical grid
is sigma coordinate with 15 layers of water column.
Abstract: In this paper, we develop an accurate and efficient Haar wavelet method for well-known FitzHugh-Nagumo equation. The proposed scheme can be used to a wide class of nonlinear reaction-diffusion equations. The power of this manageable method is confirmed. Moreover the use of Haar wavelets is found to be accurate, simple, fast, flexible, convenient, small computation costs and computationally attractive.
Abstract: Improvement in CAE methods has an important role for shortening of the vehicle product development time. It is provided that validation of the design and improvements in terms of durability can be done without hardware prototype production. In recent years, several different methods have been developed in order to investigate fatigue damage of the vehicle. The intended goal among these methods is prediction of fatigue damage in a short time with reduced costs. This study developed a new fatigue damage prediction method in the automotive sector using power spectrum densities of accelerations. This study also confirmed that the weak region in vehicle can be easily detected with the method developed in this study which results were compared with conventional method.
Abstract: Recently the use of data mining to scientific bibliographic data bases has been implemented to analyze the pathways of the knowledge or the core scientific relevances of a laureated novel or a country. This specific case of data mining has been named citation mining, and it is the integration of citation bibliometrics and text mining. In this paper we present an improved WEB implementation of statistical physics algorithms to perform the text mining component of citation mining. In particular we use an entropic like distance between the compression of text as an indicator of the similarity between them. Finally, we have included the recently proposed index h to characterize the scientific production. We have used this web implementation to identify users, applications and impact of the Mexican scientific institutions located in the State of Morelos.
Abstract: User-based Collaborative filtering (CF), one of the
most prevailing and efficient recommendation techniques, provides
personalized recommendations to users based on the opinions of other
users. Although the CF technique has been successfully applied in
various applications, it suffers from serious sparsity problems. The
cloud-model approach addresses the sparsity problems by
constructing the user-s global preference represented by a cloud
eigenvector. The user-based CF approach works well with dense
datasets while the cloud-model CF approach has a greater
performance when the dataset is sparse. In this paper, we present a
hybrid approach that integrates the predictions from both the
user-based CF and the cloud-model CF approaches. The experimental
results show that the proposed hybrid approach can ameliorate the
sparsity problem and provide an improved prediction quality.
Abstract: The Spiral development model has been used
successfully in many commercial systems and in a good number of
defense systems. This is due to the fact that cost-effective
incremental commitment of funds, via an analogy of the spiral model
to stud poker and also can be used to develop hardware or integrate
software, hardware, and systems. To support adaptive, semantic
collaboration between domain experts and knowledge engineers, a
new knowledge engineering process, called Spiral_OWL is proposed.
This model is based on the idea of iterative refinement, annotation
and structuring of knowledge base. The Spiral_OWL model is
generated base on spiral model and knowledge engineering
methodology. A central paradigm for Spiral_OWL model is the
concentration on risk-driven determination of knowledge engineering
process. The collaboration aspect comes into play during knowledge
acquisition and knowledge validation phase. Design rationales for the
Spiral_OWL model are to be easy-to-implement, well-organized, and
iterative development cycle as an expanding spiral.
Abstract: This paper describes an automatic algorithm to restore
the shape of three-dimensional (3D) left ventricle (LV) models created
from magnetic resonance imaging (MRI) data using a geometry-driven
optimization approach. Our basic premise is to restore the LV shape
such that the LV epicardial surface is smooth after the restoration. A
geometrical measure known as the Minimum Principle Curvature (κ2)
is used to assess the smoothness of the LV. This measure is used to
construct the objective function of a two-step optimization process.
The objective of the optimization is to achieve a smooth epicardial
shape by iterative in-plane translation of the MRI slices.
Quantitatively, this yields a minimum sum in terms of the magnitude
of κ
2, when κ2 is negative. A limited memory quasi-Newton algorithm,
L-BFGS-B, is used to solve the optimization problem. We tested our
algorithm on an in vitro theoretical LV model and 10 in vivo
patient-specific models which contain significant motion artifacts. The
results show that our method is able to automatically restore the shape
of LV models back to smoothness without altering the general shape of
the model. The magnitudes of in-plane translations are also consistent
with existing registration techniques and experimental findings.
Abstract: In this paper, we will generate the wreath product
11 12 M wrM using only two permutations. Also, we will show the
structure of some groups containing the wreath product 11 12 M wrM .
The structure of the groups founded is determined in terms of wreath
product k (M wrM ) wrC 11 12 . Some related cases are also included.
Also, we will show that 132K+1 S and 132K+1 A can be generated
using the wreath product k (M wrM ) wrC 11 12 and a transposition in
132K+1 S and an element of order 3 in 132K+1 A . We will also show
that 132K+1 S and 132K+1 A can be generated using the wreath
product 11 12 M wrM and an element of order k +1.
Abstract: In order to develop forest management strategies in
tropical forest in Malaysia, surveying the forest resources and
monitoring the forest area affected by logging activities is essential.
There are tremendous effort has been done in classification of land
cover related to forest resource management in this country as it is a
priority in all aspects of forest mapping using remote sensing and
related technology such as GIS. In fact classification process is a
compulsory step in any remote sensing research. Therefore, the main
objective of this paper is to assess classification accuracy of
classified forest map on Landsat TM data from difference number of
reference data (200 and 388 reference data). This comparison was
made through observation (200 reference data), and interpretation
and observation approaches (388 reference data). Five land cover
classes namely primary forest, logged over forest, water bodies, bare
land and agricultural crop/mixed horticultural can be identified by
the differences in spectral wavelength. Result showed that an overall
accuracy from 200 reference data was 83.5 % (kappa value
0.7502459; kappa variance 0.002871), which was considered
acceptable or good for optical data. However, when 200 reference
data was increased to 388 in the confusion matrix, the accuracy
slightly improved from 83.5% to 89.17%, with Kappa statistic
increased from 0.7502459 to 0.8026135, respectively. The accuracy
in this classification suggested that this strategy for the selection of
training area, interpretation approaches and number of reference data
used were importance to perform better classification result.
Abstract: This paper proposes the use of Bayesian belief
networks (BBN) as a higher level of health risk assessment for a
dumping site of lead battery smelter factory. On the basis of the
epidemiological studies, the actual hospital attendance records and
expert experiences, the BBN is capable of capturing the probabilistic
relationships between the hazardous substances and their adverse
health effects, and accordingly inferring the morbidity of the adverse
health effects. The provision of the morbidity rates of the related
diseases is more informative and can alleviate the drawbacks of
conventional methods.
Abstract: In this paper, we propose a fully-utilized, block-based 2D DWT (discrete wavelet transform) architecture, which consists of four 1D DWT filters with two-channel QMF lattice structure. The proposed architecture requires about 2MN-3N registers to save the intermediate results for higher level decomposition, where M and N stand for the filter length and the row width of the image respectively. Furthermore, the proposed 2D DWT processes in horizontal and vertical directions simultaneously without an idle period, so that it computes the DWT for an N×N image in a period of N2(1-2-2J)/3. Compared to the existing approaches, the proposed architecture shows 100% of hardware utilization and high throughput rates. To mitigate the long critical path delay due to the cascaded lattices, we can apply the pipeline technique with four stages, while retaining 100% of hardware utilization. The proposed architecture can be applied in real-time video signal processing.
Abstract: Flow movement in unsaturated soil can be expressed
by a partial differential equation, named Richards equation. The
objective of this study is the finding of an appropriate implicit
numerical solution for head based Richards equation. Some of the
well known finite difference schemes (fully implicit, Crank Nicolson
and Runge-Kutta) have been utilized in this study. In addition, the
effects of different approximations of moisture capacity function,
convergence criteria and time stepping methods were evaluated. Two
different infiltration problems were solved to investigate the
performance of different schemes. These problems include of vertical
water flow in a wet and very dry soils. The numerical solutions of
two problems were compared using four evaluation criteria and the
results of comparisons showed that fully implicit scheme is better
than the other schemes. In addition, utilizing of standard chord slope
method for approximation of moisture capacity function, automatic
time stepping method and difference between two successive
iterations as convergence criterion in the fully implicit scheme can
lead to better and more reliable results for simulation of fluid
movement in different unsaturated soils.
Abstract: The sensitivity of orifice plate metering to disturbed
flow (either asymmetric or swirling) is a subject of great concern to
flow meter users and manufacturers. The distortions caused by pipe
fittings and pipe installations upstream of the orifice plate are major
sources of this type of non-standard flows. These distortions can alter
the accuracy of metering to an unacceptable degree. In this work, a
multi-scale object known as metal foam has been used to generate a
predetermined turbulent flow upstream of the orifice plate. The
experimental results showed that the combination of an orifice plate
and metal foam flow conditioner is broadly insensitive to upstream
disturbances. This metal foam demonstrated a good performance in
terms of removing swirl and producing a repeatable flow profile
within a short distance downstream of the device. The results of using
a combination of a metal foam flow conditioner and orifice plate for
non-standard flow conditions including swirling flow and asymmetric
flow show this package can preserve the accuracy of metering up to
the level required in the standards.
Abstract: The competitive learning is an adaptive process in
which the neurons in a neural network gradually become sensitive to
different input pattern clusters. The basic idea behind the Kohonen-s
Self-Organizing Feature Maps (SOFM) is competitive learning.
SOFM can generate mappings from high-dimensional signal spaces
to lower dimensional topological structures. The main features of this
kind of mappings are topology preserving, feature mappings and
probability distribution approximation of input patterns. To overcome
some limitations of SOFM, e.g., a fixed number of neural units and a
topology of fixed dimensionality, Growing Self-Organizing Neural
Network (GSONN) can be used. GSONN can change its topological
structure during learning. It grows by learning and shrinks by
forgetting. To speed up the training and convergence, a new variant
of GSONN, twin growing cell structures (TGCS) is presented here.
This paper first gives an introduction to competitive learning, SOFM
and its variants. Then, we discuss some GSONN with fixed
dimensionality, which include growing cell structures, its variants
and the author-s model: TGCS. It is ended with some testing results
comparison and conclusions.
Abstract: The development of entrepreneurial competences of
farmers has been pointed out as a necessary condition for the
modernization of land in facing the phenomenon of globalization.
However, the educational processes involved in such a development
have been studied little, especially in emerging economies. This
research aims to enlighten some of the critical issues behind the early
stages of the transformation of farmers into entrepreneurs, through in
depth interviews with farmers, entrepreneurial promoters and public
officials participating in a public pilot project in Mexico. Although
major impacts were expected only in the long run, important positive
changes in the mind set of farmers and other participants were found
in early stages of the intervention. Apparently, the farmers started a
process of becoming more conscious about the importance of
preserving the aquiferous resources, as well as more market and
entrepreneurial oriented.
Abstract: The condition of lightning surge causes the traveling waves and the temporary increase in voltage in the transmission line system. Lightning is the most harmful for destroying the transmission line and setting devices so it is necessary to study and analyze the temporary increase in voltage for designing and setting the surge arrester. This analysis describes the figure of the lightning wave in transmission line with 115 kV voltage level in Thailand by using ATP/EMTP program to create the model of the transmission line and lightning surge. Because of the limit of this program, it must be calculated for the geometry of the transmission line and surge parameter and calculation in the manual book for the closest value of the parameter. On the other hand, for the effects on surge protector when the lightning comes, the surge arrester model must be right and standardized as metropolitan electrical authority's standard. The candidate compared the real information to the result from calculation, also. The results of the analysis show that the temporary increase in voltage value will be rise to 326.59 kV at the line which is done by lightning when the surge arrester is not set in the system. On the other hand, the temporary increase in voltage value will be 182.83 kV at the line which is done by lightning when the surge arrester is set in the system and the period of the traveling wave is reduced, also. The distance for setting the surge arrester must be as near to the transformer as possible. Moreover, it is necessary to know the right distance for setting the surge arrester and the size of the surge arrester for preventing the temporary increase in voltage, effectively.
Abstract: Metallic micro parts are playing an important role in micro-fabrication industry. Recently, we have demonstrated a new deformation mechanism for micro-formability of polycrystalline materials. Different depressed micro-features smaller than the grain size have been successfully fabricated on 6061 aluminum alloy (AA6061) substrates with good fidelity. To further verify this proposed deformation mechanism that grain size is not a limiting factor, we demonstrate here that in addition of depressed features, protruded micro-features on a polycrystalline substrate can similarly be fabricated.